Roles of 1,25(OH) 2 D 3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4 + T Cells and the PKCδ/ERK Signaling Pathway

Cellular Physiology and Biochemistry

Volumn 40, Issue 3-4, 2016, Pages 743-756

  He, Xiao Jie ^a,b   Ding, Yan ^c   Xiang, Wei ^c   Dang, Xi Qiang ^a,b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c Hainan Provincial Maternal Hospital   (China)

Author keywords

1,25(OH)2D3; CD4+ T cells; Extracellular signal regulated kinase; Protein kinase C ; Rheumatoid arthritis; Systemic lupus erythematosus; Vitamin D receptor

Indexed keywords

CALCITRIOL; CD40 LIGAND; CD70 ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE C DELTA; SMALL INTERFERING RNA; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR; LEUKOCYTE ANTIGEN; VDR PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CELL SELECTION; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DNA METHYLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ANALYSIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; VITAMIN BLOOD LEVEL; WESTERN BLOTTING; YOUNG ADULT; BLOOD; CASE CONTROL STUDY; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM;

ADULT; ANTIGENS, CD; ARTHRITIS, RHEUMATOID; CALCITRIOL; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; GENETIC VECTORS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MAP KINASE SIGNALING SYSTEM; PROTEIN KINASE C-DELTA; RECEPTORS, CALCITRIOL; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 85001555501     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000453135     Document Type: Article

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