Macrophage polarization modulates development of systemic lupus erythematosus

Cellular Physiology and Biochemistry

Volumn 37, Issue 4, 2015, Pages 1279-1288

  Li, Feng ^a   Yang, Yongsheng ^a   Zhu, Xiaohua ^a   Huang, Lan ^a   Xu, Jinhua ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Adoptive transplantation; ALD DNA; Clodronate; M1 macrophage; M2 macrophage; Macrophage polarization; Systemic lupus erythematosus (SLE)

Indexed keywords

ARGINASE; CD163 ANTIGEN; CLODRONIC ACID; DOUBLE STRANDED DNA ANTIBODY; ANTINUCLEAR ANTIBODY; DNA; GAMMA INTERFERON;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL DIFFERENTIATION; CELL ISOLATION; CELL POLARITY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; IN VITRO STUDY; LUPUS ERYTHEMATOSUS NEPHRITIS; MACROPHAGE ACTIVATION; MONOCYTE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEINURIA; SYSTEMIC LUPUS ERYTHEMATOSUS; ALLOTRANSPLANTATION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; BONE MARROW CELL; CELL CULTURE; CYTOLOGY; DOWN REGULATION; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGE; METABOLISM; PATHOLOGY; TRANSPLANTATION;

ANIMALS; ANTIBODIES, ANTINUCLEAR; BONE MARROW CELLS; CELL POLARITY; CELLS, CULTURED; CLODRONIC ACID; DNA; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTERFERON-GAMMA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; PROTEINURIA; TRANSPLANTATION, HOMOLOGOUS;

EID: 84943241115     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430251     Document Type: Article

References (29)

1. Agmon-Levin N, Blank M, Paz Z, Shoenfeld Y. Molecular mimicry in systemic lupus erythematosus. Lupus 2009;18:1181-1185.
2. Crispin JC, Tsokos GC. Novel molecular targets in the treatment of systemic lupus erythematosus. Autoimmun Rev 2008;7:256-261.
3. Crispin JC, Kyttaris V, Juang YT, Tsokos GC. Systemic lupus erythematosus: New molecular targets. Ann Rheum Dis 2007;66:Suppl iii65-69.
4. Vilaiyuk S, Sirachainan N, Wanitkun S, Pirojsakul K, Vaewpanich J. Recurrent macrophage activation syndrome as the primary manifestation in systemic lupus erythematosus and the benefit of serial ferritin measurements: A case-based review. Clin Rheumatol 2013;32:899-904.
5. Orme J, Mohan C. Macrophage subpopulations in systemic lupus erythematosus. Discov Med 2012;13:151-158.
6. Li Y, Lee PY, Reeves WH. Monocyte and macrophage abnormalities in systemic lupus erythematosus. Arch Immunol Ther Exp (Warsz) 2010;58:355-364.
7. Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3:23-35.
8. Gordon S, Martinez FO. Alternative activation of macrophages: Mechanism and functions. Immunity 2010;32:593-604.
9. Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science 2010;327:656-661.
10. Ricardo SD, van Goor H, Eddy AA. Macrophage diversity in renal injury and repair. J Clin Invest 2008;118:3522-3530.
11. Xiao X, Gaffar I, Guo P, Wiersch J, Fischbach S, Peirish L, Song Z, El-Gohary Y, Prasadan K, Shiota C, Gittes GK. M2 macrophages promote beta-cell proliferation by up-regulation of smad7. Proc Natl Acad Sci U S A 2014;111:E1211-1220.
12. Mills CD. M1 and m2 macrophages: Oracles of health and disease. Crit Rev Immunol 2012;32:463-488.
13. Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM. M-1/m-2 macrophages and the th1/th2 paradigm. J Immunol 2000;164:6166-6173.
14. Claassen E, Van Rooijen N. The effect of elimination of macrophages on the tissue distribution of liposomes containing [3h]methotrexate. Biochim Biophys Acta 1984;802:428-434.
15. van Rooijen N, van Nieuwmegen R. Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study. Cell Tissue Res 1984;238:355-358.
16. Plosker GL, Goa KL. Clodronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease. Drugs 1994;47:945-982.
17. Atkins CD. Clodronate in metastatic breast cancer. N Engl J Med 1998;339:1941.
18. Diel IJ, Solomayer EF, Costa SD, Gollan C, Goerner R, Wallwiener D, Kaufmann M, Bastert G. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998;339:357-363.
19. Meli M, Rausa L. Clodronate in metastatic breast cancer. N Engl J Med 1998;339:1940; author reply 1941.
20. Panasci LC, Sandor V, Melnychuk D. Clodronate in metastatic breast cancer. N Engl J Med 1998;339:1940-1941; author reply 1941.
21. Saad F. Should patients with prostate cancer without bone metastases receive sodium clodronate? Nature clinical practice Urology 2007;4:584-585.
22. Richards PJ, Williams AS, Goodfellow RM, Williams BD. Liposomal clodronate eliminates synovial macrophages, reduces inflammation and ameliorates joint destruction in antigen-induced arthritis. Rheumatology (Oxford) 1999;38:818-825.
23. Pan B, Liu G, Jiang Z, Zheng D. Regulation of renal fibrosis by macrophage polarization. Cell Physiol Biochem 2015;35:1062-1069.
24. Shen B, Liu X, Fan Y, Qiu J. Macrophages regulate renal fibrosis through modulating TGFbeta superfamily signaling. Inflammation 2014;37:2076-2084.
25. Zhang W, Xu W, Xiong S. Macrophage differentiation and polarization via phosphatidylinositol 3-kinase/akt-erk signaling pathway conferred by serum amyloid p component. J Immunol 2011;187:1764-1777.
26. Wen ZK, Xu W, Xu L, Cao QH, Wang Y, Chu YW, Xiong SD. DNA hypomethylation is crucial for apoptotic DNA to induce systemic lupus erythematosus-like autoimmune disease in sle-non-susceptible mice. Rheumatology (Oxford) 2007;46:1796-1803.
27. Qiao B, Wu J, Chu YW, Wang Y, Wang DP, Wu HS, Xiong SD. Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA. Rheumatology (Oxford) 2005;44:1108-1114.
28. Weischenfeldt J, Porse B. Bone marrow-derived macrophages (BMM): Isolation and applications. CSH Protocols 2008;2008:pdb prot5080.
29. Davis BK. Isolation, culture, and functional evaluation of bone marrow-derived macrophages. Methods Mol Biol 2013;1031:27-35.