-
1
-
-
33751566645
-
DUSP meet immunology dual specificity MAPK phosphatases in control of the inflammatory response
-
Lang, R., Hammer, M. & Mages, J. DUSP meet immunology dual specificity MAPK phosphatases in control of the inflammatory response. J. Immunol. 177, 7497-7504 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 7497-7504
-
-
Lang, R.1
Hammer, M.2
Mages, J.3
-
2
-
-
34248210189
-
Targeting dual-specificity phosphatases manipulating MAP kinase signalling and immune responses
-
Jeffrey, K. L., Camps, M., Rommel, C. & Mackay, C. R. Targeting dual-specificity phosphatases manipulating MAP kinase signalling and immune responses. Nat. Rev. Drug. Discov. 6, 391-403 (2007).
-
(2007)
Nat. Rev. Drug. Discov
, vol.6
, pp. 391-403
-
-
Jeffrey, K.L.1
Camps, M.2
Rommel, C.3
Mackay, C.R.4
-
3
-
-
33846472047
-
Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development
-
Li, C., Scott, D. A., Hatch, E., Tian, X. & Mansour, S. L. Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development. Development 134, 167-176 (2007).
-
(2007)
Development
, vol.134
, pp. 167-176
-
-
Li, C.1
Scott, D.A.2
Hatch, E.3
Tian, X.4
Mansour, S.L.5
-
4
-
-
57649198454
-
DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility
-
Maillet, M. et al. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility. J. Biol. Chem. 283, 31246-31255 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 31246-31255
-
-
Maillet, M.1
-
5
-
-
84903385943
-
FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice
-
Feng, B., He, Q. & Xu, H. FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice. Mol. Cell. Endocrinol. 393, 46-55 (2014).
-
(2014)
Mol. Cell. Endocrinol
, vol.393
, pp. 46-55
-
-
Feng, B.1
He, Q.2
Xu, H.3
-
6
-
-
84906699251
-
Mitogen-activated protein kinase phosphatase 3 (MKP-3)-deficient mice are resistant to diet-induced obesity
-
Feng, B. et al. Mitogen-activated protein kinase phosphatase 3 (MKP-3)-deficient mice are resistant to diet-induced obesity. Diabetes 63, 2924-2934 (2014).
-
(2014)
Diabetes
, vol.63
, pp. 2924-2934
-
-
Feng, B.1
-
7
-
-
79957902145
-
Gut microbiome, obesity, and metabolic dysfunction
-
Tilg, H. & Kaser, A. Gut microbiome, obesity, and metabolic dysfunction. J. Clin. Invest. 121, 2126-2132 (2011).
-
(2011)
J. Clin. Invest
, vol.121
, pp. 2126-2132
-
-
Tilg, H.1
Kaser, A.2
-
8
-
-
84921626523
-
Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity
-
Everard, A. et al. Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity. ISME J. 8, 2116-2130 (2014).
-
(2014)
ISME J
, vol.8
, pp. 2116-2130
-
-
Everard, A.1
-
9
-
-
84908348194
-
Meta-analyses of human gut microbes associated with obesity and IBD
-
Walters, W. A., Xu, Z. & Knight, R. Meta-analyses of human gut microbes associated with obesity and IBD. FEBS Lett. 588, 4223-4233 (2014).
-
(2014)
FEBS Lett
, vol.588
, pp. 4223-4233
-
-
Walters, W.A.1
Xu, Z.2
Knight, R.3
-
10
-
-
84872156123
-
Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice
-
Parks, B. W. et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metab. 17, 141-152 (2013).
-
(2013)
Cell Metab
, vol.17
, pp. 141-152
-
-
Parks, B.W.1
-
11
-
-
33947269742
-
Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities
-
Lozupone, C. A., Hamady, M., Kelley, S. T. & Knight, R. Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities. Appl. Environ. Microbiol. 73, 1576-1585 (2007).
-
(2007)
Appl. Environ. Microbiol
, vol.73
, pp. 1576-1585
-
-
Lozupone, C.A.1
Hamady, M.2
Kelley, S.T.3
Knight, R.4
-
12
-
-
78751575501
-
UniFrac: An effective distance metric for microbial community comparison
-
Lozupone, C., Lladser, M. E., Knights, D., Stombaugh, J. & Knight, R. UniFrac: an effective distance metric for microbial community comparison. ISME J. 5, 169-172 (2011).
-
(2011)
ISME J
, vol.5
, pp. 169-172
-
-
Lozupone, C.1
Lladser, M.E.2
Knights, D.3
Stombaugh, J.4
Knight, R.5
-
13
-
-
33845901507
-
Microbial ecology human gut microbes associated with obesity
-
Ley, R. E., Turnbaugh, P. J., Klein, S. & Gordon, J. I. Microbial ecology human gut microbes associated with obesity. Nature 444, 1022-1023 (2006).
-
(2006)
Nature
, vol.444
, pp. 1022-1023
-
-
Ley, R.E.1
Turnbaugh, P.J.2
Klein, S.3
Gordon, J.I.4
-
14
-
-
79958248593
-
Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides/Prevotella in diet-induced obese mice
-
Neyrinck, A. M. et al. Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides/Prevotella in diet-induced obese mice. PLoS ONE 6, e20944 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Neyrinck, A.M.1
-
15
-
-
80055045344
-
Obesity and the gut microbiota: Does up-regulating colonic fermentation protect against obesity and metabolic disease?
-
Conterno, L., Fava, F., Viola, R. & Tuohy, K. M. Obesity and the gut microbiota: does up-regulating colonic fermentation protect against obesity and metabolic disease? Genes Nutr. 6, 241-260 (2011).
-
(2011)
Genes Nutr
, vol.6
, pp. 241-260
-
-
Conterno, L.1
Fava, F.2
Viola, R.3
Tuohy, K.M.4
-
16
-
-
60549086580
-
Human gut microbiota in obesity and after gastric bypass
-
Zhang, H. et al. Human gut microbiota in obesity and after gastric bypass. Proc. Natl Acad. Sci. USA 106, 2365-2370 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 2365-2370
-
-
Zhang, H.1
-
17
-
-
84878465280
-
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
-
Everard, A. et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc. Natl Acad. Sci. USA 110, 9066-9071 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 9066-9071
-
-
Everard, A.1
-
18
-
-
84888258892
-
Ten quick tips for using the gene ontology
-
Blake, J. A. Ten quick tips for using the gene ontology. PLoS Comput. Biol. 9, e1003343 (2013).
-
(2013)
PLoS Comput. Biol
, vol.9
-
-
Blake, J.A.1
-
19
-
-
84912080990
-
Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms
-
Citalan-Madrid, A. F., Garcia-Ponce, A., Vargas-Robles, H., Betanzos, A. & Schnoor, M. Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms. Tissue Barriers 1, e26938 (2013).
-
(2013)
Tissue Barriers
, vol.1
-
-
Citalan-Madrid, A.F.1
Garcia-Ponce, A.2
Vargas-Robles, H.3
Betanzos, A.4
Schnoor, M.5
-
20
-
-
0029145667
-
Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians
-
Norman, R. A., Bogardus, C. & Ravussin, E. Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians. J. Clin. Invest. 96, 158-162 (1995).
-
(1995)
J. Clin. Invest
, vol.96
, pp. 158-162
-
-
Norman, R.A.1
Bogardus, C.2
Ravussin, E.3
-
21
-
-
77954562818
-
Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians
-
Mahajan, A. et al. Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians. J. Mol. Med. 88, 515-522 (2010).
-
(2010)
J. Mol. Med
, vol.88
, pp. 515-522
-
-
Mahajan, A.1
-
22
-
-
84866547629
-
Lymphotoxin regulates commensal responses to enable diet-induced obesity
-
Upadhyay, V. et al. Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nat. Immunol. 13, 947-953 (2012).
-
(2012)
Nat. Immunol
, vol.13
, pp. 947-953
-
-
Upadhyay, V.1
-
23
-
-
84925358255
-
ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation
-
Tornavaca, O. et al. ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. J. Cell Biol. 208, 821-838 (2015).
-
(2015)
J. Cell Biol
, vol.208
, pp. 821-838
-
-
Tornavaca, O.1
-
24
-
-
48249125862
-
Changes in gut microbiota control metabolic endotoxemiainduced inflammation in high-fat diet-induced obesity and diabetes in mice
-
Cani, P. D. et al. Changes in gut microbiota control metabolic endotoxemiainduced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57, 1470-1481 (2008).
-
(2008)
Diabetes
, vol.57
, pp. 1470-1481
-
-
Cani, P.D.1
-
25
-
-
74049122536
-
Enteric defensins are essential regulators of intestinal microbial ecology
-
Salzman, N. H. et al. Enteric defensins are essential regulators of intestinal microbial ecology. Nat. Immunol. 11, 76-83 (2010).
-
(2010)
Nat. Immunol
, vol.11
, pp. 76-83
-
-
Salzman, N.H.1
-
26
-
-
84896851032
-
Intestinal epithelial cells regulators of barrier function and immune homeostasis
-
Peterson, L. W. & Artis, D. Intestinal epithelial cells regulators of barrier function and immune homeostasis. Nat. Rev. Immunol. 14, 141-153 (2014).
-
(2014)
Nat. Rev. Immunol
, vol.14
, pp. 141-153
-
-
Peterson, L.W.1
Artis, D.2
-
27
-
-
75649147911
-
TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice
-
Gonzalez-Navajas, J. M. et al. TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice. J. Clin. Invest. 120, 570-581 (2010).
-
(2010)
J. Clin. Invest
, vol.120
, pp. 570-581
-
-
Gonzalez-Navajas, J.M.1
-
28
-
-
84928890449
-
Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice
-
Bertin, S. et al. Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice. Mucosal Immunol. 8, 505-515 (2015).
-
(2015)
Mucosal Immunol
, vol.8
, pp. 505-515
-
-
Bertin, S.1
-
29
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva, M. & O'Garra, A. The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 10, 170-181 (2010).
-
(2010)
Nat. Rev. Immunol
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
30
-
-
84880470281
-
Altered enteric microbiota ecology in interleukin 10-deficient mice during development and progression of intestinal inflammation
-
Maharshak, N. et al. Altered enteric microbiota ecology in interleukin 10-deficient mice during development and progression of intestinal inflammation. Gut Microbes 4, 316-324 (2013).
-
(2013)
Gut Microbes
, vol.4
, pp. 316-324
-
-
Maharshak, N.1
-
31
-
-
84881247044
-
Intestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticus-induced colitis
-
Yang, I. et al. Intestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticus-induced colitis. PLoS ONE 8, e70783 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Yang, I.1
-
32
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger, J. & Moller, D. E. The mechanisms of action of PPARs. Annu. Rev. Med. 53, 409-435 (2002).
-
(2002)
Annu. Rev. Med
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
33
-
-
42749103304
-
PPARs obesity, and inflammation
-
Stienstra, R., Duval, C., Muller, M. & Kersten, S. PPARs, obesity, and inflammation. PPAR Res. 2007, 95974 (2007).
-
(2007)
PPAR Res 2007
-
-
Stienstra, R.1
Duval, C.2
Muller, M.3
Kersten, S.4
-
34
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver, P. et al. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839 (1998).
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
-
35
-
-
78049448761
-
MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice
-
Wu, Z. et al. MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice. J. Clin. Invest. 120, 3901-3911 (2010).
-
(2010)
J. Clin. Invest
, vol.120
, pp. 3901-3911
-
-
Wu, Z.1
-
36
-
-
84943664277
-
MAP kinase phosphatase 3 inhibits brown adipocyte differentiation via regulation of Erk phosphorylation
-
Kim, W. K. et al. MAP kinase phosphatase 3 inhibits brown adipocyte differentiation via regulation of Erk phosphorylation. Mol. Cell Endocrinol. 416, 70-76 (2015).
-
(2015)
Mol. Cell Endocrinol
, vol.416
, pp. 70-76
-
-
Kim, W.K.1
-
37
-
-
84911884131
-
The gut microbiota influences blood-brain barrier permeability in mice
-
Braniste, V. et al. The gut microbiota influences blood-brain barrier permeability in mice. Sci. Transl. Med. 6, 263ra158 (2014).
-
(2014)
Sci. Transl. Med
, vol.6
-
-
Braniste, V.1
-
38
-
-
77952243141
-
QIIME allows analysis of high-throughput community sequencing data
-
Caporaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nat. Methods 7, 335-336 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 335-336
-
-
Caporaso, J.G.1
-
39
-
-
77957244650
-
Search and clustering orders of magnitude faster than BLAST
-
Edgar, R. C. Search and clustering orders of magnitude faster than BLAST. Bioinformatics 26, 2460-2461 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2460-2461
-
-
Edgar, R.C.1
-
40
-
-
84857122937
-
An improved greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea
-
McDonald, D. et al. An improved greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea. ISME J. 6, 610-618 (2012).
-
(2012)
ISME J
, vol.6
, pp. 610-618
-
-
McDonald, D.1
-
41
-
-
34548293679
-
Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy
-
Wang, Q., Garrity, G. M., Tiedje, J. M. & Cole, J. R. Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. Appl. Environ. Microbiol. 73, 5261-5267 (2007).
-
(2007)
Appl. Environ. Microbiol
, vol.73
, pp. 5261-5267
-
-
Wang, Q.1
Garrity, G.M.2
Tiedje, J.M.3
Cole, J.R.4
-
42
-
-
29144464937
-
UniFrac: A new phylogenetic method for comparing microbial communities
-
Lozupone, C. & Knight, R. UniFrac: a new phylogenetic method for comparing microbial communities. Appl. Environ. Microbiol. 71, 8228-8235 (2005).
-
(2005)
Appl. Environ. Microbiol
, vol.71
, pp. 8228-8235
-
-
Lozupone, C.1
Knight, R.2
-
43
-
-
84871809302
-
STAR ultrafast universal RNA-seq aligner
-
Dobin, A. et al. STAR ultrafast universal RNA-seq aligner. Bioinformatics 29, 15-21 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 15-21
-
-
Dobin, A.1
-
44
-
-
84924629414
-
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
-
Love, M. I., Huber, W. & Anders, S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15, 550 (2014).
-
(2014)
Genome Biol
, vol.15
, pp. 550
-
-
Love, M.I.1
Huber, W.2
Anders, S.3
-
45
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang, D. W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57 (2009).
-
(2009)
Nat. Protoc
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
46
-
-
58549112996
-
Bioinformatics enrichment tools paths toward the comprehensive functional analysis of large gene lists
-
Huang, D. W., Sherman, B. T. & Lempicki, R. A. Bioinformatics enrichment tools paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 37, 1-13 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1-13
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
47
-
-
84855171722
-
Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers
-
Chen, E. Y. et al. Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers. Bioinformatics 28, 105-111 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 105-111
-
-
Chen, E.Y.1
-
48
-
-
0242490780
-
Cytoscape a software environment for integrated models of biomolecular interaction networks
-
Shannon, P. et al. Cytoscape a software environment for integrated models of biomolecular interaction networks. Genome Res. 13, 2498-2504 (2003).
-
(2003)
Genome Res
, vol.13
, pp. 2498-2504
-
-
Shannon, P.1
-
49
-
-
84862655609
-
Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling
-
Liao, Y. C. et al. Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling. Oncogene 31, 3086-3097 (2012).
-
(2012)
Oncogene
, vol.31
, pp. 3086-3097
-
-
Liao, Y.C.1
-
50
-
-
79952714142
-
Cell growing density affects the structural and functional properties of Caco-2 differentiated monolayer
-
Natoli, M. et al. Cell growing density affects the structural and functional properties of Caco-2 differentiated monolayer. J. Cell Physiol. 226, 1531-1543 (2011).
-
(2011)
J. Cell Physiol
, vol.226
, pp. 1531-1543
-
-
Natoli, M.1
|