메뉴 건너뛰기




Volumn 37, Issue 12, 2016, Pages 877-888

Harnessing NK Cell Memory for Cancer Immunotherapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ACTIVITY; CANCER IMMUNOTHERAPY; DIFFERENTIATION; HUMAN; MEMORY; NATURAL KILLER CELL; ADOPTIVE IMMUNOTHERAPY; ANIMAL; CELL DIFFERENTIATION; CYTOMEGALOVIRUS; CYTOTOXICITY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; METABOLISM; MOUSE; NEOPLASMS; PROCEDURES; TRANSPLANTATION;

EID: 84999663822     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2016.09.005     Document Type: Review
Times cited : (87)

References (69)
  • 1
    • 84887315668 scopus 로고    scopus 로고
    • Natural killer cells
    • W. Paul Lippincott Williams & Wilkins
    • 1 Yokoyama, W.M., Natural killer cells. Paul, W., (eds.) Fundamental Immunology, 2013, Lippincott Williams & Wilkins, 395–430.
    • (2013) Fundamental Immunology , pp. 395-430
    • Yokoyama, W.M.1
  • 2
    • 78650970845 scopus 로고    scopus 로고
    • Innate or adaptive immunity? The example of natural killer cells
    • 2 Vivier, E., et al. Innate or adaptive immunity? The example of natural killer cells. Science 331 (2011), 44–49.
    • (2011) Science , vol.331 , pp. 44-49
    • Vivier, E.1
  • 3
    • 33645989497 scopus 로고    scopus 로고
    • T cell- and B cell-independent adaptive immunity mediated by natural killer cells
    • 3 O'Leary, J.G., et al. T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat. Immunol. 7 (2006), 507–516.
    • (2006) Nat. Immunol. , vol.7 , pp. 507-516
    • O'Leary, J.G.1
  • 4
    • 60549091350 scopus 로고    scopus 로고
    • Cytokine-induced memory-like natural killer cells
    • 4 Cooper, M.A., et al. Cytokine-induced memory-like natural killer cells. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 1915–1919.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 1915-1919
    • Cooper, M.A.1
  • 5
    • 59049094662 scopus 로고    scopus 로고
    • Adaptive immune features of natural killer cells
    • 5 Sun, J.C., et al. Adaptive immune features of natural killer cells. Nature 457 (2009), 557–561.
    • (2009) Nature , vol.457 , pp. 557-561
    • Sun, J.C.1
  • 6
    • 84897965451 scopus 로고    scopus 로고
    • Clinical utility of natural killer cells in cancer therapy and transplantation
    • 6 Knorr, D.A., et al. Clinical utility of natural killer cells in cancer therapy and transplantation. Semin. Immunol. 26 (2014), 161–172.
    • (2014) Semin. Immunol. , vol.26 , pp. 161-172
    • Knorr, D.A.1
  • 7
    • 84947129611 scopus 로고    scopus 로고
    • Improving natural killer cell cancer immunotherapy
    • 7 Berrien-Elliott, M.M., et al. Improving natural killer cell cancer immunotherapy. Curr. Opin. Organ Transplant. 20 (2015), 671–680.
    • (2015) Curr. Opin. Organ Transplant. , vol.20 , pp. 671-680
    • Berrien-Elliott, M.M.1
  • 8
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • 8 Ruggeri, L., et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295 (2002), 2097–2100.
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1
  • 9
    • 77951684782 scopus 로고    scopus 로고
    • Memory-like responses of natural killer cells
    • 9 Cooper, M.A., Yokoyama, W.M., Memory-like responses of natural killer cells. Immunol. Rev. 235 (2010), 297–305.
    • (2010) Immunol. Rev. , vol.235 , pp. 297-305
    • Cooper, M.A.1    Yokoyama, W.M.2
  • 10
    • 78449275107 scopus 로고    scopus 로고
    • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses
    • 10 Paust, S., et al. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat. Immunol. 11 (2010), 1127–1135.
    • (2010) Nat. Immunol. , vol.11 , pp. 1127-1135
    • Paust, S.1
  • 11
    • 84875862176 scopus 로고    scopus 로고
    • Liver-resident NK cells confer adaptive immunity in skin-contact inflammation
    • 11 Peng, H., et al. Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J. Clin. Invest. 123 (2013), 1444–1456.
    • (2013) J. Clin. Invest. , vol.123 , pp. 1444-1456
    • Peng, H.1
  • 12
    • 77951685718 scopus 로고    scopus 로고
    • Adaptive immune responses mediated by natural killer cells
    • 12 Paust, S., et al. Adaptive immune responses mediated by natural killer cells. Immunol. Rev. 235 (2010), 286–296.
    • (2010) Immunol. Rev. , vol.235 , pp. 286-296
    • Paust, S.1
  • 13
    • 84883244942 scopus 로고    scopus 로고
    • Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-alpha, interferon-gamma and interleukin-12
    • 13 Majewska-Szczepanik, M., et al. Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-alpha, interferon-gamma and interleukin-12. Immunology 140 (2013), 98–110.
    • (2013) Immunology , vol.140 , pp. 98-110
    • Majewska-Szczepanik, M.1
  • 14
    • 84973541067 scopus 로고    scopus 로고
    • Inflammasome-dependent induction of adaptive NK cell memory
    • 14 van den Boorn, J.G., et al. Inflammasome-dependent induction of adaptive NK cell memory. Immunity 44 (2016), 1406–1421.
    • (2016) Immunity , vol.44 , pp. 1406-1421
    • van den Boorn, J.G.1
  • 15
    • 79960914933 scopus 로고    scopus 로고
    • Unifying concepts of MHC-dependent natural killer cell education
    • 15 Elliott, J.M., Yokoyama, W.M., Unifying concepts of MHC-dependent natural killer cell education. Trends Immunol. 32 (2011), 364–372.
    • (2011) Trends Immunol. , vol.32 , pp. 364-372
    • Elliott, J.M.1    Yokoyama, W.M.2
  • 16
    • 84939652785 scopus 로고    scopus 로고
    • Antigen-specific NK cell memory in rhesus macaques
    • 16 Reeves, R.K., et al. Antigen-specific NK cell memory in rhesus macaques. Nat. Immunol. 16 (2015), 927–932.
    • (2015) Nat. Immunol. , vol.16 , pp. 927-932
    • Reeves, R.K.1
  • 17
    • 0024315206 scopus 로고
    • Severe herpesvirus infections in an adolescent without natural killer cells
    • 17 Biron, C.A., et al. Severe herpesvirus infections in an adolescent without natural killer cells. N. Engl. J. Med. 320 (1989), 1731–1735.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1731-1735
    • Biron, C.A.1
  • 18
    • 50949100398 scopus 로고    scopus 로고
    • Human NK cells can control CMV infection in the absence of T cells
    • 18 Kuijpers, T.W., et al. Human NK cells can control CMV infection in the absence of T cells. Blood 112 (2008), 914–915.
    • (2008) Blood , vol.112 , pp. 914-915
    • Kuijpers, T.W.1
  • 19
    • 0034774942 scopus 로고    scopus 로고
    • Specific and nonspecific NK cell activation during virus infection
    • 19 Dokun, A.O., et al. Specific and nonspecific NK cell activation during virus infection. Nat. Immunol. 2 (2001), 951–956.
    • (2001) Nat. Immunol. , vol.2 , pp. 951-956
    • Dokun, A.O.1
  • 20
    • 0037172968 scopus 로고    scopus 로고
    • Recognition of a virus-encoded ligand by a natural killer cell activation receptor
    • 20 Smith, H.R., et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc. Natl. Acad. Sci. U. S. A. 99 (2002), 8826–8831.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 8826-8831
    • Smith, H.R.1
  • 21
    • 0037123607 scopus 로고    scopus 로고
    • Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors
    • 21 Arase, H., et al. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 296 (2002), 1323–1326.
    • (2002) Science , vol.296 , pp. 1323-1326
    • Arase, H.1
  • 22
    • 51249086859 scopus 로고    scopus 로고
    • Ly49h is necessary for genetic resistance to murine cytomegalovirus
    • 22 Cheng, T.P., et al. Ly49h is necessary for genetic resistance to murine cytomegalovirus. Immunogenetics 60 (2008), 565–573.
    • (2008) Immunogenetics , vol.60 , pp. 565-573
    • Cheng, T.P.1
  • 23
    • 84863804916 scopus 로고    scopus 로고
    • Proinflammatory cytokine signaling required for the generation of natural killer cell memory
    • 23 Sun, J.C., et al. Proinflammatory cytokine signaling required for the generation of natural killer cell memory. J. Exp. Med. 209 (2012), 947–954.
    • (2012) J. Exp. Med. , vol.209 , pp. 947-954
    • Sun, J.C.1
  • 24
    • 84894261203 scopus 로고    scopus 로고
    • Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection
    • 24 Nabekura, T., et al. Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection. Immunity 40 (2014), 225–234.
    • (2014) Immunity , vol.40 , pp. 225-234
    • Nabekura, T.1
  • 25
    • 84944676758 scopus 로고    scopus 로고
    • Natural killer cell memory
    • 25 O'Sullivan, T.E., et al. Natural killer cell memory. Immunity 43 (2015), 634–645.
    • (2015) Immunity , vol.43 , pp. 634-645
    • O'Sullivan, T.E.1
  • 26
    • 84901057914 scopus 로고    scopus 로고
    • The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection
    • 26 Beaulieu, A.M., et al. The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection. Nat. Immunol. 15 (2014), 546–553.
    • (2014) Nat. Immunol. , vol.15 , pp. 546-553
    • Beaulieu, A.M.1
  • 27
    • 84940978095 scopus 로고    scopus 로고
    • BNIP3- and BNIP3L-mediated mitophagy promotes the generation of natural killer cell memory
    • 27 O'Sullivan, T.E., et al. BNIP3- and BNIP3L-mediated mitophagy promotes the generation of natural killer cell memory. Immunity 43 (2015), 331–342.
    • (2015) Immunity , vol.43 , pp. 331-342
    • O'Sullivan, T.E.1
  • 28
    • 84903780487 scopus 로고    scopus 로고
    • Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection
    • 28 Min-Oo, G., et al. Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection. J. Exp. Med. 211 (2014), 1289–1296.
    • (2014) J. Exp. Med. , vol.211 , pp. 1289-1296
    • Min-Oo, G.1
  • 29
    • 9444273448 scopus 로고    scopus 로고
    • Imprint of human cytomegalovirus infection on the NK cell receptor repertoire
    • 29 Guma, M., et al. Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood 104 (2004), 3664–3671.
    • (2004) Blood , vol.104 , pp. 3664-3671
    • Guma, M.1
  • 30
    • 84959559396 scopus 로고    scopus 로고
    • Immune adaptation to environmental influence: the case of NK cells and HCMV
    • 30 Rolle, A., Brodin, P., Immune adaptation to environmental influence: the case of NK cells and HCMV. Trends Immunol. 37 (2016), 233–243.
    • (2016) Trends Immunol. , vol.37 , pp. 233-243
    • Rolle, A.1    Brodin, P.2
  • 31
    • 80052602721 scopus 로고    scopus 로고
    • hi natural killer cell subset during acute human cytomegalovirus infection
    • hi natural killer cell subset during acute human cytomegalovirus infection. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 14725–14732.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 14725-14732
    • Lopez-Verges, S.1
  • 32
    • 84863338121 scopus 로고    scopus 로고
    • + natural killer cells with potent function
    • + natural killer cells with potent function. Blood 119 (2012), 2665–2674.
    • (2012) Blood , vol.119 , pp. 2665-2674
    • Foley, B.1
  • 33
    • 84871282021 scopus 로고    scopus 로고
    • Spotlight on NKG2C and the human NK-cell response to CMV infection
    • 33 Malmberg, K.J., et al. Spotlight on NKG2C and the human NK-cell response to CMV infection. Eur. J. Immunol. 42 (2012), 3141–3145.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 3141-3145
    • Malmberg, K.J.1
  • 34
  • 35
    • 84924984567 scopus 로고    scopus 로고
    • Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function
    • 35 Schlums, H., et al. Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function. Immunity 42 (2015), 443–456.
    • (2015) Immunity , vol.42 , pp. 443-456
    • Schlums, H.1
  • 36
    • 84924955835 scopus 로고    scopus 로고
    • Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals
    • 36 Lee, J., et al. Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals. Immunity 42 (2015), 431–442.
    • (2015) Immunity , vol.42 , pp. 431-442
    • Lee, J.1
  • 37
    • 84870369284 scopus 로고    scopus 로고
    • Identification of human NK cells that are deficient for signaling adaptor FcRγ and specialized for antibody-dependent immune functions
    • 37 Hwang, I., et al. Identification of human NK cells that are deficient for signaling adaptor FcRγ and specialized for antibody-dependent immune functions. Int. Immunol. 24 (2012), 793–802.
    • (2012) Int. Immunol. , vol.24 , pp. 793-802
    • Hwang, I.1
  • 38
    • 84873565353 scopus 로고    scopus 로고
    • Cutting edge: antibody-dependent memory-like NK cells distinguished by FcRγ deficiency
    • 38 Zhang, T., et al. Cutting edge: antibody-dependent memory-like NK cells distinguished by FcRγ deficiency. J. Immunol. 190 (2013), 1402–1406.
    • (2013) J. Immunol. , vol.190 , pp. 1402-1406
    • Zhang, T.1
  • 39
    • 84896716290 scopus 로고    scopus 로고
    • −/− umbilical cord blood
    • −/− umbilical cord blood. J. Immunol. 192 (2014), 1471–1479.
    • (2014) J. Immunol. , vol.192 , pp. 1471-1479
    • Della Chiesa, M.1
  • 40
    • 84963954943 scopus 로고    scopus 로고
    • Critical role of CD2 co-stimulation in adaptive natural killer cell responses revealed in NKG2C-deficient humans
    • 40 Liu, L.L., et al. Critical role of CD2 co-stimulation in adaptive natural killer cell responses revealed in NKG2C-deficient humans. Cell Rep. 15 (2016), 1088–1099.
    • (2016) Cell Rep. , vol.15 , pp. 1088-1099
    • Liu, L.L.1
  • 41
    • 84876796202 scopus 로고    scopus 로고
    • Murine NK cell intrinsic cytokine-induced memory-like responses are maintained following homeostatic proliferation
    • 41 Keppel, M.P., et al. Murine NK cell intrinsic cytokine-induced memory-like responses are maintained following homeostatic proliferation. J. Immunol. 190 (2013), 4754–4762.
    • (2013) J. Immunol. , vol.190 , pp. 4754-4762
    • Keppel, M.P.1
  • 42
    • 84870736330 scopus 로고    scopus 로고
    • Cytokine activation induces human memory-like NK cells
    • 42 Romee, R., et al. Cytokine activation induces human memory-like NK cells. Blood 120 (2012), 4751–4760.
    • (2012) Blood , vol.120 , pp. 4751-4760
    • Romee, R.1
  • 43
    • 84895832116 scopus 로고    scopus 로고
    • Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells
    • 43 Leong, J.W., et al. Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells. Biol. Blood Marrow Transplant. 20 (2014), 463–473.
    • (2014) Biol. Blood Marrow Transplant. , vol.20 , pp. 463-473
    • Leong, J.W.1
  • 44
    • 84959322789 scopus 로고    scopus 로고
    • + NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT
    • + NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT. Leukemia 30 (2016), 456–463.
    • (2016) Leukemia , vol.30 , pp. 456-463
    • Cichocki, F.1
  • 45
    • 84978819065 scopus 로고    scopus 로고
    • + NK cells in healthy humans
    • + NK cells in healthy humans. Clin. Exp. Immunol. 185 (2016), 239–251.
    • (2016) Clin. Exp. Immunol. , vol.185 , pp. 239-251
    • Bigley, A.B.1
  • 46
    • 80051560743 scopus 로고    scopus 로고
    • Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patients
    • 46 Elmaagacli, A.H., et al. Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patients. Blood 118 (2011), 1402–1412.
    • (2011) Blood , vol.118 , pp. 1402-1412
    • Elmaagacli, A.H.1
  • 47
    • 84885584038 scopus 로고    scopus 로고
    • CMV reactivation is associated with a lower incidence of relapse after allo-SCT for CML
    • 47 Ito, S., et al. CMV reactivation is associated with a lower incidence of relapse after allo-SCT for CML. Bone Marrow Transplant. 48 (2013), 1313–1316.
    • (2013) Bone Marrow Transplant. , vol.48 , pp. 1313-1316
    • Ito, S.1
  • 48
    • 84887151263 scopus 로고    scopus 로고
    • CMV reactivation after allogeneic HCT and relapse risk: evidence for early protection in acute myeloid leukemia
    • 48 Green, M.L., et al. CMV reactivation after allogeneic HCT and relapse risk: evidence for early protection in acute myeloid leukemia. Blood 122 (2013), 1316–1324.
    • (2013) Blood , vol.122 , pp. 1316-1324
    • Green, M.L.1
  • 49
    • 84957609686 scopus 로고    scopus 로고
    • Naive donor NK cell repertoires associated with less leukemia relapse after allogeneic hematopoietic stem cell transplantation
    • 49 Björklund, A.T., et al. Naive donor NK cell repertoires associated with less leukemia relapse after allogeneic hematopoietic stem cell transplantation. J. Immunol. 196 (2016), 1400–1411.
    • (2016) J. Immunol. , vol.196 , pp. 1400-1411
    • Björklund, A.T.1
  • 50
    • 84872225254 scopus 로고    scopus 로고
    • Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors
    • 50 Ni, J., et al. Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J. Exp. Med. 209 (2012), 2351–2365.
    • (2012) J. Exp. Med. , vol.209 , pp. 2351-2365
    • Ni, J.1
  • 51
    • 84988409805 scopus 로고    scopus 로고
    • + T cell help
    • Published online August 5, 2016
    • + T cell help. Oncoimmunology, 2016, 10.1080/2162402X.2016.1219009 Published online August 5, 2016.
    • (2016) Oncoimmunology
    • Ni, J.1
  • 52
    • 84988876317 scopus 로고    scopus 로고
    • Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
    • 52 Romee, R., et al. Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia. Sci. Transl. Med., 8, 2016, 357ra123.
    • (2016) Sci. Transl. Med. , vol.8 , pp. 357ra123
    • Romee, R.1
  • 54
    • 84902682889 scopus 로고    scopus 로고
    • Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
    • 54 Bachanova, V., et al. Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein. Blood 123 (2014), 3855–3863.
    • (2014) Blood , vol.123 , pp. 3855-3863
    • Bachanova, V.1
  • 55
    • 80053208226 scopus 로고    scopus 로고
    • Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients
    • 55 Curti, A., et al. Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients. Blood 118 (2011), 3273–3279.
    • (2011) Blood , vol.118 , pp. 3273-3279
    • Curti, A.1
  • 56
    • 84899744468 scopus 로고    scopus 로고
    • + tumor cells
    • + tumor cells. mAbs 6 (2014), 728–739.
    • (2014) mAbs , vol.6 , pp. 728-739
    • Reusch, U.1
  • 57
    • 84903215048 scopus 로고    scopus 로고
    • + targets
    • + targets. Blood 123 (2014), 3016–3026.
    • (2014) Blood , vol.123 , pp. 3016-3026
    • Gleason, M.K.1
  • 58
    • 84933505755 scopus 로고    scopus 로고
    • A Phase 1 study of the bispecific anti-CD30/CD16A antibody construct AFM13 in patients with relapsed or refractory Hodgkin lymphoma
    • 58 Rothe, A., et al. A Phase 1 study of the bispecific anti-CD30/CD16A antibody construct AFM13 in patients with relapsed or refractory Hodgkin lymphoma. Blood 125 (2015), 4024–4031.
    • (2015) Blood , vol.125 , pp. 4024-4031
    • Rothe, A.1
  • 59
    • 84982103393 scopus 로고    scopus 로고
    • Enhanced ADCC and NK cell activation of an anticarcinoma bispecific antibody by genetic insertion of a modified IL-15 cross-linker
    • 59 Schmohl, J.U., et al. Enhanced ADCC and NK cell activation of an anticarcinoma bispecific antibody by genetic insertion of a modified IL-15 cross-linker. Mol. Ther. 24 (2016), 1312–1322.
    • (2016) Mol. Ther. , vol.24 , pp. 1312-1322
    • Schmohl, J.U.1
  • 60
    • 84898461706 scopus 로고    scopus 로고
    • CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
    • 60 Chu, J., et al. CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma. Leukemia 28 (2014), 917–927.
    • (2014) Leukemia , vol.28 , pp. 917-927
    • Chu, J.1
  • 61
    • 84934297331 scopus 로고    scopus 로고
    • Utilizing chimeric antigen receptors to direct natural killer cell activity
    • 61 Hermanson, D.L., Kaufman, D.S., Utilizing chimeric antigen receptors to direct natural killer cell activity. Front. Immunol., 6, 2015, 195.
    • (2015) Front. Immunol. , vol.6 , pp. 195
    • Hermanson, D.L.1    Kaufman, D.S.2
  • 62
    • 84989961356 scopus 로고    scopus 로고
    • Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells
    • Published online August 8, 2016
    • 62 Sarhan, D., et al. Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells. Cancer Res., 2016, 10.1158/0008-5472.CAN-16-0839 Published online August 8, 2016.
    • (2016) Cancer Res.
    • Sarhan, D.1
  • 63
    • 0037460058 scopus 로고    scopus 로고
    • Interleukin (IL)-15Rα-deficient natural killer cells survive in normal but not IL-15Rα-deficient mice
    • 63 Koka, R., et al. Interleukin (IL)-15Rα-deficient natural killer cells survive in normal but not IL-15Rα-deficient mice. J. Exp. Med. 197 (2003), 977–984.
    • (2003) J. Exp. Med. , vol.197 , pp. 977-984
    • Koka, R.1
  • 64
    • 1642577125 scopus 로고    scopus 로고
    • Turnover and proliferation of NK cells in steady state and lymphopenic conditions
    • 64 Jamieson, A.M., et al. Turnover and proliferation of NK cells in steady state and lymphopenic conditions. J. Immunol. 172 (2004), 864–870.
    • (2004) J. Immunol. , vol.172 , pp. 864-870
    • Jamieson, A.M.1
  • 65
    • 84961554501 scopus 로고    scopus 로고
    • The shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapy
    • 65 Waldmann, T.A., The shared and contrasting roles of IL2 and IL15 in the life and death of normal and neoplastic lymphocytes: implications for cancer therapy. Cancer Immunol. Res. 3 (2015), 219–227.
    • (2015) Cancer Immunol. Res. , vol.3 , pp. 219-227
    • Waldmann, T.A.1
  • 66
    • 84920828341 scopus 로고    scopus 로고
    • Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer
    • 66 Romee, R., et al. Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer. Scientifica (Cairo), 2014, 2014, 205796.
    • (2014) Scientifica (Cairo) , vol.2014 , pp. 205796
    • Romee, R.1
  • 67
    • 78651492046 scopus 로고    scopus 로고
    • Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus
    • 67 Björkstrom, N.K., et al. Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. J. Exp. Med. 208 (2011), 13–21.
    • (2011) J. Exp. Med. , vol.208 , pp. 13-21
    • Björkstrom, N.K.1
  • 68
    • 80053440812 scopus 로고    scopus 로고
    • Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity
    • 68 Petitdemange, C., et al. Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity. PLoS Pathog., 7, 2011, e1002268.
    • (2011) PLoS Pathog. , vol.7 , pp. e1002268
    • Petitdemange, C.1
  • 69
    • 84922590130 scopus 로고    scopus 로고
    • Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection
    • 69 Min-Oo, G., Lanier, L.L., Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection. J. Exp. Med. 211 (2014), 2669–2680.
    • (2014) J. Exp. Med. , vol.211 , pp. 2669-2680
    • Min-Oo, G.1    Lanier, L.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.