Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

Science Translational Medicine

Volumn 8, Issue 357, 2016, Pages

  Romee, Rizwan ^a   Rosario, Maximillian ^a   Berrien Elliott, Melissa M ^a   Wagner, Julia A ^a   Jewell, Brea A ^a   Schappe, Timothy ^a   Leong, Jeffrey W ^a   Abdel Latif, Sara ^a   Schneider, Stephanie E ^a   Willey, Sarah ^a   Neal, Carly C ^a   Yu, Liyang ^a   Oh, Stephen T ^a   Lee, Yi Shan ^a   Mulder, Arend ^b   Claas, Frans ^b   Cooper, Megan A ^a   Fehniger, Todd A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; CYCLOPHOSPHAMIDE; CYTOKINE RECEPTOR; FLUDARABINE; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 18; INTERLEUKIN 2 RECEPTOR ALPHA; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; L SELECTIN; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3; NATURAL KILLER CELL RECEPTOR NKG2A; RECOMBINANT INTERLEUKIN 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; CYTOKINE; LIGAND; NATURAL KILLER CELL RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADOPTIVE IMMUNOTHERAPY; ADOPTIVE TRANSFER; ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLAST CELL; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL MEDIATED CYTOTOXICITY; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; DRUG DOSE ESCALATION; FEMALE; FLOW CYTOMETRY; GRAFT VERSUS HOST REACTION; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC CELL; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOPHENOTYPING; IN VIVO STUDY; INTERFERON PRODUCTION; LEUKAPHERESIS; LEUKEMIA REMISSION; LOW DRUG DOSE; MALE; MASS SPECTROMETRY; MEMORY CELL; NATURAL KILLER CELL; NONHUMAN; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; SEPTIC SHOCK; ACUTE MYELOID LEUKEMIA; ANIMAL; CLINICAL TRIAL; DRUG EFFECTS; DRUG SCREENING; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MOUSE; PATHOLOGY; PHASE 1 CLINICAL TRIAL; REMISSION;

ADOPTIVE TRANSFER; AGED; ANIMALS; CELL PROLIFERATION; CYTOKINES; FEMALE; HUMANS; IMMUNOLOGIC MEMORY; KILLER CELLS, NATURAL; LEUKEMIA, MYELOID, ACUTE; LIGANDS; MALE; MICE; MIDDLE AGED; RECEPTORS, NATURAL KILLER CELL; REMISSION INDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84988876317     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaf2341     Document Type: Article

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