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Volumn 8, Issue 12, 2016, Pages 1366-1379

Gut microbiota influences pathological angiogenesis in obesity-driven choroidal neovascularization

Author keywords

age related macular degeneration; angiogenesis; gut microbiota; inflammaging; obesity

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; VASCULOTROPIN A; CYTOKINE;

EID: 84999651985     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201606531     Document Type: Article
Times cited : (145)

References (69)
  • 2
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
    • Age-Related Eye Disease Study Research Group (2001) A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 119: 1417–1436
    • (2001) Arch Ophthalmol , vol.119 , pp. 1417-1436
  • 3
    • 84877734641 scopus 로고    scopus 로고
    • Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial
    • Age-Related Eye Disease Study 2 Research Group (2013) Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. J Am Med Assoc 309: 2005–2015
    • (2013) J Am Med Assoc , vol.309 , pp. 2005-2015
  • 5
    • 0038708118 scopus 로고    scopus 로고
    • Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies
    • Ambati J, Ambati B, Yoo S, Ianchulev S, Adamis A (2003a) Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies. Surv Ophthalmol 48: 257–293
    • (2003) Surv Ophthalmol , vol.48 , pp. 257-293
    • Ambati, J.1    Ambati, B.2    Yoo, S.3    Ianchulev, S.4    Adamis, A.5
  • 7
    • 84878214672 scopus 로고    scopus 로고
    • Immunology of age-related macular degeneration
    • Ambati J, Atkinson J, Gelfand B (2013) Immunology of age-related macular degeneration. Nat Rev Immunol 13: 438–451
    • (2013) Nat Rev Immunol , vol.13 , pp. 438-451
    • Ambati, J.1    Atkinson, J.2    Gelfand, B.3
  • 10
    • 84962374584 scopus 로고    scopus 로고
    • Age-related macular degeneration: genome-wide association studies to translation
    • Black JR, Clark SJ (2016) Age-related macular degeneration: genome-wide association studies to translation. Genet Med 18: 283–289
    • (2016) Genet Med , vol.18 , pp. 283-289
    • Black, J.R.1    Clark, S.J.2
  • 12
    • 84943454450 scopus 로고    scopus 로고
    • Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
    • Caesar R, Tremaroli V, Kovatcheva-Datchary P, Cani PD, Backhed F (2015) Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling. Cell Metab 22: 658–668
    • (2015) Cell Metab , vol.22 , pp. 658-668
    • Caesar, R.1    Tremaroli, V.2    Kovatcheva-Datchary, P.3    Cani, P.D.4    Backhed, F.5
  • 14
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani P, Bibiloni R, Knauf C, Waget A, Neyrinck A, Delzenne N, Burcelin R (2008) Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57: 1470–1481
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.5    Delzenne, N.6    Burcelin, R.7
  • 15
    • 77957236209 scopus 로고    scopus 로고
    • The immune system and the gut microbiota: friends or foes?
    • Cerf-Bensussan N, Gaboriau-Routhiau V (2010) The immune system and the gut microbiota: friends or foes? Nat Rev Immunol 10: 735–744
    • (2010) Nat Rev Immunol , vol.10 , pp. 735-744
    • Cerf-Bensussan, N.1    Gaboriau-Routhiau, V.2
  • 16
    • 84892691172 scopus 로고    scopus 로고
    • Gut microbiota, low-grade inflammation, and metabolic syndrome
    • Chassaing B, Gewirtz AT (2014) Gut microbiota, low-grade inflammation, and metabolic syndrome. Toxicol Pathol 42: 49–53
    • (2014) Toxicol Pathol , vol.42 , pp. 49-53
    • Chassaing, B.1    Gewirtz, A.T.2
  • 17
    • 84944103518 scopus 로고    scopus 로고
    • Parainflammation, chronic inflammation, and age-related macular degeneration
    • Chen M, Xu H (2015) Parainflammation, chronic inflammation, and age-related macular degeneration. J Leukoc Biol 98: 713–725
    • (2015) J Leukoc Biol , vol.98 , pp. 713-725
    • Chen, M.1    Xu, H.2
  • 21
    • 84871640601 scopus 로고    scopus 로고
    • Impact of the Gut Microbiota on the Development of Obesity: Current Concepts
    • DiBaise JK, Frank DN, Mathur R (2012) Impact of the Gut Microbiota on the Development of Obesity: Current Concepts. Am J Gastroenterol Suppl 1: 22–27
    • (2012) Am J Gastroenterol Suppl , vol.1 , pp. 22-27
    • DiBaise, J.K.1    Frank, D.N.2    Mathur, R.3
  • 22
    • 84902657623 scopus 로고    scopus 로고
    • Finding the missing links among metabolites, microbes, and the host
    • Dorrestein PC, Mazmanian SK, Knight R (2014) Finding the missing links among metabolites, microbes, and the host. Immunity 40: 824–832
    • (2014) Immunity , vol.40 , pp. 824-832
    • Dorrestein, P.C.1    Mazmanian, S.K.2    Knight, R.3
  • 26
    • 84900988267 scopus 로고    scopus 로고
    • Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
    • Franceschi C, Campisi J (2014) Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci 69(Suppl 1): S4–S9
    • (2014) J Gerontol A Biol Sci Med Sci , vol.69 , pp. S4-S9
    • Franceschi, C.1    Campisi, J.2
  • 30
    • 79955839320 scopus 로고    scopus 로고
    • Increased intestinal permeability in inflammatory bowel diseases assessed by iohexol test
    • Gerova VA, Stoynov SG, Katsarov DS, Svinarov DA (2011) Increased intestinal permeability in inflammatory bowel diseases assessed by iohexol test. World J Gastroenterol 17: 2211–2215
    • (2011) World J Gastroenterol , vol.17 , pp. 2211-2215
    • Gerova, V.A.1    Stoynov, S.G.2    Katsarov, D.S.3    Svinarov, D.A.4
  • 34
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch UK, Kettenmann H (2007) Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10: 1387–1394
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 37
    • 84925011456 scopus 로고    scopus 로고
    • 7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration
    • Indaram M, Ma W, Zhao L, Fariss R, Rodriguez I, Wong W (2015) 7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration. Sci Rep 5: 9144
    • (2015) Sci Rep , vol.5 , pp. 9144
    • Indaram, M.1    Ma, W.2    Zhao, L.3    Fariss, R.4    Rodriguez, I.5    Wong, W.6
  • 38
    • 1842556545 scopus 로고    scopus 로고
    • Do statins prevent age-related macular degeneration?
    • Klein R, Klein BEK (2004) Do statins prevent age-related macular degeneration? Am J Ophthalmol 137: 747–749
    • (2004) Am J Ophthalmol , vol.137 , pp. 747-749
    • Klein, R.1    Klein, B.E.K.2
  • 40
    • 53149137799 scopus 로고    scopus 로고
    • Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis
    • et, al
    • Klein R, Knudtson M, Klein BEK, Wong T, Cotch M, Liu K, Cheng C, Burke G, Saad M, Jacobs D et al (2008) Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis. Ophthalmology 115: 1742–1749
    • (2008) Ophthalmology , vol.115 , pp. 1742-1749
    • Klein, R.1    Knudtson, M.2    Klein, B.E.K.3    Wong, T.4    Cotch, M.5    Liu, K.6    Cheng, C.7    Burke, G.8    Saad, M.9    Jacobs, D.10
  • 41
    • 84898639156 scopus 로고    scopus 로고
    • Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study
    • Klein R, Myers C, Cruickshanks K, Gangnon R, Danforth L, Sivakumaran T, Iyengar S, Tsai M, Klein BEK (2014) Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study. JAMA Ophthalmol 132: 446–455
    • (2014) JAMA Ophthalmol , vol.132 , pp. 446-455
    • Klein, R.1    Myers, C.2    Cruickshanks, K.3    Gangnon, R.4    Danforth, L.5    Sivakumaran, T.6    Iyengar, S.7    Tsai, M.8    Klein, B.E.K.9
  • 43
    • 34249744612 scopus 로고    scopus 로고
    • Microglia activation in retinal degeneration
    • Langmann T (2007) Microglia activation in retinal degeneration. J Leukoc Biol 81: 1345–1351
    • (2007) J Leukoc Biol , vol.81 , pp. 1345-1351
    • Langmann, T.1
  • 44
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R, Turnbaugh P, Klein S, Gordon J (2006) Microbial ecology: human gut microbes associated with obesity. Nature 444: 1022–1023
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.1    Turnbaugh, P.2    Klein, S.3    Gordon, J.4
  • 45
    • 84881590982 scopus 로고    scopus 로고
    • Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice
    • et, al
    • Liu J, Copland D, Horie S, Wu W-K, Chen M, Xu Y, Paul Morgan B, Mack M, Xu H, Nicholson L et al (2013) Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice. PLoS One 8: e72935
    • (2013) PLoS One , vol.8
    • Liu, J.1    Copland, D.2    Horie, S.3    Wu, W.-K.4    Chen, M.5    Xu, Y.6    Paul Morgan, B.7    Mack, M.8    Xu, H.9    Nicholson, L.10
  • 46
    • 84964703061 scopus 로고    scopus 로고
    • Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization
    • Luckoff A, Caramoy A, Scholz R, Prinz M, Kalinke U, Langmann T (2016) Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization. EMBO Mol Med 8: 670–678
    • (2016) EMBO Mol Med , vol.8 , pp. 670-678
    • Luckoff, A.1    Caramoy, A.2    Scholz, R.3    Prinz, M.4    Kalinke, U.5    Langmann, T.6
  • 48
    • 78650465542 scopus 로고    scopus 로고
    • Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk
    • Manco M, Putignani L, Bottazzo GF (2010) Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk. Endocr Rev 31: 817–844
    • (2010) Endocr Rev , vol.31 , pp. 817-844
    • Manco, M.1    Putignani, L.2    Bottazzo, G.F.3
  • 49
    • 84887318014 scopus 로고    scopus 로고
    • The Gordian Knot of dysbiosis, obesity and NAFLD
    • Mehal WZ (2013) The Gordian Knot of dysbiosis, obesity and NAFLD. Nat Rev Gastroenterol Hepatol 10: 637–644
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 637-644
    • Mehal, W.Z.1
  • 52
    • 84857985148 scopus 로고    scopus 로고
    • The cellular and signaling networks linking the immune system and metabolism in disease
    • Osborn O, Olefsky JM (2012) The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 18: 363–374
    • (2012) Nat Med , vol.18 , pp. 363-374
    • Osborn, O.1    Olefsky, J.M.2
  • 53
    • 84948992933 scopus 로고    scopus 로고
    • Gut microbiota and aging
    • O'Toole PW, Jeffery IB (2015) Gut microbiota and aging. Science 350: 1214–1215
    • (2015) Science , vol.350 , pp. 1214-1215
    • O'Toole, P.W.1    Jeffery, I.B.2
  • 54
    • 84906317107 scopus 로고    scopus 로고
    • Microglia: unique and common features with other tissue macrophages
    • Prinz M, Tay TL, Wolf Y, Jung S (2014) Microglia: unique and common features with other tissue macrophages. Acta Neuropathol 128: 319–331
    • (2014) Acta Neuropathol , vol.128 , pp. 319-331
    • Prinz, M.1    Tay, T.L.2    Wolf, Y.3    Jung, S.4
  • 55
    • 84880169545 scopus 로고    scopus 로고
    • Age-related macular degeneration-clinical review and genetics update
    • Ratnapriya R, Chew EY (2013) Age-related macular degeneration-clinical review and genetics update. Clin Genet 84: 160–166
    • (2013) Clin Genet , vol.84 , pp. 160-166
    • Ratnapriya, R.1    Chew, E.Y.2
  • 57
    • 0038010714 scopus 로고    scopus 로고
    • Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio
    • Seddon J, Cote J, Davis N, Rosner B (2003) Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio. Arch Ophthalmol 121: 785–792
    • (2003) Arch Ophthalmol , vol.121 , pp. 785-792
    • Seddon, J.1    Cote, J.2    Davis, N.3    Rosner, B.4
  • 59
    • 84887096324 scopus 로고    scopus 로고
    • CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice
    • et, al
    • Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, Hu SJ, Dominguez E, Camelo S, Levy O, Guyon E et al (2013) CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. EMBO Mol Med 5: 1775–1793
    • (2013) EMBO Mol Med , vol.5 , pp. 1775-1793
    • Sennlaub, F.1    Auvynet, C.2    Calippe, B.3    Lavalette, S.4    Poupel, L.5    Hu, S.J.6    Dominguez, E.7    Camelo, S.8    Levy, O.9    Guyon, E.10
  • 60
    • 84899081985 scopus 로고    scopus 로고
    • Nature and nurture- genes and environment- predict onset and progression of macular degeneration
    • Sobrin L, Seddon J (2014) Nature and nurture- genes and environment- predict onset and progression of macular degeneration. Prog Retin Eye Res 40: 1–15
    • (2014) Prog Retin Eye Res , vol.40 , pp. 1-15
    • Sobrin, L.1    Seddon, J.2
  • 62
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V, Backhed F (2012) Functional interactions between the gut microbiota and host metabolism. Nature 489: 242–249
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 64
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P, Ley R, Mahowald M, Magrini V, Mardis E, Gordon J (2006) An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444: 1027–1031
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.1    Ley, R.2    Mahowald, M.3    Magrini, V.4    Mardis, E.5    Gordon, J.6
  • 65
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh P, Ridaura V, Faith J, Rey F, Knight R, Gordon J (2009) The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 1: 6ra14
    • (2009) Sci Transl Med , vol.1 , pp. 6ra14
    • Turnbaugh, P.1    Ridaura, V.2    Faith, J.3    Rey, F.4    Knight, R.5    Gordon, J.6
  • 66
    • 84892965801 scopus 로고    scopus 로고
    • Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
    • Wong WL, Su X, Li X, Cheung CM, Klein R, Cheng CY, Wong TY (2014) Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob Health 2: e106–e116
    • (2014) Lancet Glob Health , vol.2 , pp. e106-e116
    • Wong, W.L.1    Su, X.2    Li, X.3    Cheung, C.M.4    Klein, R.5    Cheng, C.Y.6    Wong, T.Y.7


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