Do statins prevent age-related macular degeneration?

American Journal of Ophthalmology

Volumn 137, Issue 4, 2004, Pages 747-749

  Klein, Ronald ^a,b   Klein, Barbara E K ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTILIPEMIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

AGE DETERMINATION; AGED; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; CONFIDENCE INTERVAL; DISEASE COURSE; EDITORIAL; ENDOTHELIUM INJURY; FOLLOW UP; HUMAN; LASER COAGULATION; MAJOR CLINICAL STUDY; OXIDATIVE STRESS; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; RISK ASSESSMENT; SEX DIFFERENCE; SMOKING; STATISTICAL SIGNIFICANCE;

ASPIRIN; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MACULAR DEGENERATION;

EID: 1842556545     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2004.01.037     Document Type: Editorial

References (17)

1. Tielsch JM. Vision problems in the U.S. A report on blindness and vision impairment in adults age 40 and older. Schaumburg, IL: Prevent Blindness America, 1995:1-20
2. Klein R., Wang Q., Klein B.E.K., Moss S.E., Meuer S.M. The relationship of age-related maculopathy, cataract, and glaucoma to visual acuity. Invest Ophthalmol Vis Sci. 36:1995;182-191.
3. Bressler N.M., Bressler S.B., Fine S.L. Age-related macular degeneration. Surv Ophthalmol. 32:1988;375-413.
4. Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization. Arch Ophthalmol 1993;111:1189-1199
5. Bressler N.M. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin two-year results of 2 randomized clinical trials-TAP report 2. Arch Ophthalmol. 119:2001;198-207.
6. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age- related macular degeneration and vision loss. AREDS Report No. 8. Arch Ophthalmol. 119:2001;1417-1436.
7. Wilson HL, Schwartz DM, Bhatt HRF, McCulloch CE, Duncan JL. Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among age-related macular degeneration patients. Am J Ophthalmol 2004;137:615-624
8. Hall N.F., Gale C.R., Syddall H., Phillips D.I.W., Martyn C.N. Risk of macular degeneration in users of statins cross sectional study. BMJ. 323:2001;375-376.
9. McCarty C.A., Mukesh B.N., Guymer R.H., Baird P.N., Taylor H.R. Cholesterol-lowering medications reduce the risk of age-related maculopathy progression. Let Med J Aust. 175:2001;340.
10. McGwin G. Jr., Owsley C., Curcio C.A., Crain R.J. The association between statin use and age related maculopathy. Br J Ophthalmol. 87:2003;1121-1125.
11. van Leeuwen R., Vingerling J.R., Hofman A., de Jong P.T.V.M., Stricker B.H.C. Cholesterol lowering drugs and risk of age related maculopathy prospective cohort study with cumulative exposure measurement. BMJ. 326:2003;255-256.
12. Klein R., Klein B.E.K., Tomany S.C., Danforth L.G., Cruickshanks K.J. Relation of statin use to the 5-year incidence and progression of age-related maculopathy. Arch Ophthalmol. 121:2003;1151-1155.
13. Delcourt C., Michel F., Colvez A., Lacroux A., Delage M., Vernet M.H. Associations of cardiovascular disease and its risk factors with age-related macular degeneration the POLA study. Ophthal Epidemiol. 8:2001;237-249.
14. van Leeuwen R, Tomany SC, Wang JJ, et al. Is medication use associated with the incidence of early age-related maculopathy? Pooled findings from three continents. Ophthalmology. Forthcoming
15. Tomany SC, Wang JJ, van Leeuwen, Klein R et al. Risk factors for incident age-related macular degeneration: pooled findings from three continents. Ophthalmology. Forthcoming
16. Klein R., Klein B.E.K., Jensen S.C., Cruickshanks J.K., et al. Medication use and the 5-year incidence of early age-related maculopathy The Beaver Dam Eye Study. Arch Ophthalmol. 119:2001;1354-1359.
17. Christen W.G., Glynn R.J., Ajani U.A., et al. Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians. Arch Ophthalmol. 119:2001;1143-1149.