메뉴 건너뛰기




Volumn 14, Issue 6, 2016, Pages 5385-5394

Antihypertensive therapy improves insulin resistance and serum levels of interleukin-6 and-10 in spontaneously hypertensive rats with steatohepatitis

Author keywords

Hypertension; Insulin resistance; Interleukin 10; Interleukin 6; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Regulatory T cell

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; AMINO ACID; AMLODIPINE; CD4 ANTIGEN; CD68 ANTIGEN; CHOLESTEROL; CHOLINE; GLUCOSE; HYDRALAZINE; INSULIN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR FOXP3; TRIACYLGLYCEROL; ANTIHYPERTENSIVE AGENT; BIOLOGICAL MARKER; CD68 ANTIGEN, HUMAN; DIFFERENTIATION ANTIGEN; GLUCOSE BLOOD LEVEL; LEUKOCYTE ANTIGEN;

EID: 84999115042     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.5875     Document Type: Article
Times cited : (11)

References (47)
  • 1
    • 84922998556 scopus 로고    scopus 로고
    • Clinical features of hepatocellular carcinoma associated with nonalcoholic fatty liver disease: A review of human studies
    • Oda K, Uto H, Mawatari S and Ido A: Clinical features of hepatocellular carcinoma associated with nonalcoholic fatty liver disease: A review of human studies. Clin J Gastroenterol 8: 1-9, 2015.
    • (2015) Clin J Gastroenterol , vol.8 , pp. 1-9
    • Oda, K.1    Uto, H.2    Mawatari, S.3    Ido, A.4
  • 3
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology and the American Gastroenterological Association
    • Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, Charlton M and Sanyal AJ: The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology and the American Gastroenterological Association. Hepatology 55: 2005-2023, 2012.
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6    Charlton, M.7    Sanyal, A.J.8
  • 4
    • 75449102165 scopus 로고    scopus 로고
    • Long-term mortality in nonalcoholic fatty liver disease: Is liver histology of any prognostic significance?
    • Angulo P: Long-term mortality in nonalcoholic fatty liver disease: Is liver histology of any prognostic significance? Hepatology 51: 373-375, 2010.
    • (2010) Hepatology , vol.51 , pp. 373-375
    • Angulo, P.1
  • 6
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
    • Tilg H and Moschen AR: Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis. Hepatology 52: 1836-1846, 2010.
    • (2010) Hepatology , vol.52 , pp. 1836-1846
    • Tilg, H.1    Moschen, A.R.2
  • 7
    • 84922622191 scopus 로고    scopus 로고
    • A concise review of non-alcoholic fatty liver disease
    • Than NN and Newsome PN: A concise review of non-alcoholic fatty liver disease. Atherosclerosis 239: 192-202, 2015.
    • (2015) Atherosclerosis , vol.239 , pp. 192-202
    • Than, N.N.1    Newsome, P.N.2
  • 8
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies
    • Prospective Studies Collaboration
    • Lewington S, Clarke R, Qizilbash N, Peto R and Collins R; Prospective Studies Collaboration: Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360: 1903-1913, 2002.
    • (2002) Lancet , vol.360 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 9
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
    • INTERHEART Study Investigators
    • Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J and Lisheng L; INTERHEART Study Investigators: Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet 364: 937-952, 2004.
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Dans, T.4    Avezum, A.5    Lanas, F.6    McQueen, M.7    Budaj, A.8    Pais, P.9    Varigos, J.10    Lisheng, L.11
  • 10
    • 77955014011 scopus 로고    scopus 로고
    • Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study
    • INTERSTROKE investigators
    • O'Donnell MJ, Xavier D, Liu L, Zhang H, Chin SL, Rao-Melacini P, Rangarajan S, Islam S, Pais P, McQueen MJ, et al; INTERSTROKE investigators: Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study. Lancet 376: 112-123, 2010.
    • (2010) Lancet , vol.376 , pp. 112-123
    • O'Donnell, M.J.1    Xavier, D.2    Liu, L.3    Zhang, H.4    Chin, S.L.5    Rao-Melacini, P.6    Rangarajan, S.7    Islam, S.8    Pais, P.9    McQueen, M.J.10
  • 13
    • 84881478224 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and cardiovascular risk
    • Brea A and Puzo J: Non-alcoholic fatty liver disease and cardiovascular risk. Int J Cardiol 167: 1109-1117, 2013.
    • (2013) Int J Cardiol , vol.167 , pp. 1109-1117
    • Brea, A.1    Puzo, J.2
  • 14
    • 3042521502 scopus 로고    scopus 로고
    • Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: Role of insulin resistance
    • Donati G, Stagni B, Piscaglia F, Venturoli N, Morselli-Labate AM, Rasciti L and Bolondi L: Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: Role of insulin resistance. Gut 53: 1020-1023, 2004.
    • (2004) Gut , vol.53 , pp. 1020-1023
    • Donati, G.1    Stagni, B.2    Piscaglia, F.3    Venturoli, N.4    Morselli-Labate, A.M.5    Rasciti, L.6    Bolondi, L.7
  • 25
    • 34047212750 scopus 로고    scopus 로고
    • Human T and natural killer cells possess a functional renin-angiotensin system: Further mechanisms of angiotensin II-induced inflammation
    • Jurewicz M, McDermott DH, Sechler JM, Tinckam K, Takakura A, Carpenter CB, Milford E and Abdi R: Human T and natural killer cells possess a functional renin-angiotensin system: Further mechanisms of angiotensin II-induced inflammation. J Am Soc Nephrol 18: 1093-1102, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1093-1102
    • Jurewicz, M.1    McDermott, D.H.2    Sechler, J.M.3    Tinckam, K.4    Takakura, A.5    Carpenter, C.B.6    Milford, E.7    Abdi, R.8
  • 26
    • 84916897951 scopus 로고    scopus 로고
    • Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension
    • González GE, Rhaleb NE, D'Ambrosio MA, Nakagawa P, Liu Y, Leung P, Dai X, Yang XP, Peterson EL and Carretero OA: Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension. J Hypertens 33: 144-152, 2015.
    • (2015) J Hypertens , vol.33 , pp. 144-152
    • González, G.E.1    Rhaleb, N.E.2    D'Ambrosio, M.A.3    Nakagawa, P.4    Liu, Y.5    Leung, P.6    Dai, X.7    Yang, X.P.8    Peterson, E.L.9    Carretero, O.A.10
  • 27
    • 3242772924 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein: Clinical importance
    • Bassuk SS, Rifai N and Ridker PM: High-sensitivity C-reactive protein: Clinical importance. Curr Probl Cardiol 29: 439-493, 2004.
    • (2004) Curr Probl Cardiol , vol.29 , pp. 439-493
    • Bassuk, S.S.1    Rifai, N.2    Ridker, P.M.3
  • 28
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE and Rifai N: C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342: 836-843, 2000.
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 29
    • 79251645456 scopus 로고    scopus 로고
    • Interleukin-6 as an independent predictor of future cardiovascular events in high-risk Japanese patients: Comparison with C-reactive protein
    • Nishida H, Horio T, Suzuki Y, Iwashima Y, Tokudome T, Yoshihara F, Nakamura S and Kawano Y: Interleukin-6 as an independent predictor of future cardiovascular events in high-risk Japanese patients: Comparison with C-reactive protein. Cytokine 53: 342-346, 2011.
    • (2011) Cytokine , vol.53 , pp. 342-346
    • Nishida, H.1    Horio, T.2    Suzuki, Y.3    Iwashima, Y.4    Tokudome, T.5    Yoshihara, F.6    Nakamura, S.7    Kawano, Y.8
  • 30
    • 0032754882 scopus 로고    scopus 로고
    • Inflammatory markers in men with angiographically documented coronary heart disease
    • Rifai N, Joubran R, Yu H, Asmi M and Jouma M: Inflammatory markers in men with angiographically documented coronary heart disease. Clin Chem 45: 1967-1973, 1999.
    • (1999) Clin Chem , vol.45 , pp. 1967-1973
    • Rifai, N.1    Joubran, R.2    Yu, H.3    Asmi, M.4    Jouma, M.5
  • 32
    • 12144274058 scopus 로고    scopus 로고
    • Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats
    • Rotter Sopasakis V, Larsson BM, Johansson A, Holmäng A and Smith U: Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats. Diabetologia 47: 1879-1887, 2004.
    • (2004) Diabetologia , vol.47 , pp. 1879-1887
    • Rotter Sopasakis, V.1    Larsson, B.M.2    Johansson, A.3    Holmäng, A.4    Smith, U.5
  • 33
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
    • Rotter V, Nagaev I and Smith U: Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278: 45777-45784, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 34
    • 0242299763 scopus 로고    scopus 로고
    • Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: Prevention by rosiglitazone
    • Lagathu C, Bastard JP, Auclair M, Maachi M, Capeau J and Caron M: Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: Prevention by rosiglitazone. Biochem Biophys Res Commun 311: 372-379, 2003.
    • (2003) Biochem Biophys Res Commun , vol.311 , pp. 372-379
    • Lagathu, C.1    Bastard, J.P.2    Auclair, M.3    Maachi, M.4    Capeau, J.5    Caron, M.6
  • 35
    • 23044468612 scopus 로고    scopus 로고
    • Interleukin-6 depletion selectively improves hepatic insulin action in obesity
    • Klover PJ, Clementi AH and Mooney RA: Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology 146: 3417-3427, 2005.
    • (2005) Endocrinology , vol.146 , pp. 3417-3427
    • Klover, P.J.1    Clementi, A.H.2    Mooney, R.A.3
  • 36
    • 0242268894 scopus 로고    scopus 로고
    • Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
    • Klover PJ, Zimmers TA, Koniaris LG and Mooney RA: Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 52: 2784-2789, 2003.
    • (2003) Diabetes , vol.52 , pp. 2784-2789
    • Klover, P.J.1    Zimmers, T.A.2    Koniaris, L.G.3    Mooney, R.A.4
  • 37
    • 84999258625 scopus 로고    scopus 로고
    • The impact of cytokines and chemokines on non-alcoholic fatty liver disease (NAFLD)
    • Meda C: The impact of cytokines and chemokines on non-alcoholic fatty liver disease (NAFLD). Biotech Mol Biol Nanomed 2: 15-16, 2014.
    • (2014) Biotech Mol Biol Nanomed , vol.2 , pp. 15-16
    • Meda, C.1
  • 44
    • 77951146612 scopus 로고    scopus 로고
    • C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
    • Obstfeld AE, Sugaru E, Thearle M, Francisco AM, Gayet C, Ginsberg HN, Ables EV and Ferrante AW Jr: C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis. Diabetes 59: 916-925, 2010.
    • (2010) Diabetes , vol.59 , pp. 916-925
    • Obstfeld, A.E.1    Sugaru, E.2    Thearle, M.3    Francisco, A.M.4    Gayet, C.5    Ginsberg, H.N.6    Ables, E.V.7    Ferrante, A.W.8
  • 45
    • 78649681353 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet
    • Kassel KM, Guo GL, Tawfik O and Luyendyk JP: Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet. Lab Invest 90: 1794-1804, 2010.
    • (2010) Lab Invest , vol.90 , pp. 1794-1804
    • Kassel, K.M.1    Guo, G.L.2    Tawfik, O.3    Luyendyk, J.P.4
  • 46
    • 84906535982 scopus 로고    scopus 로고
    • Roles for chemokines in liver disease
    • Marra F and Tacke F: Roles for chemokines in liver disease. Gastroenterology 147: 577-594, 2014.
    • (2014) Gastroenterology , vol.147 , pp. 577-594
    • Marra, F.1    Tacke, F.2
  • 47
    • 84888795580 scopus 로고    scopus 로고
    • Morphological and functional characterization of non-alcoholic fatty liver disease induced by a methionine-choline-deficient diet in C57BL/6 mice
    • Itagaki H, Shimizu K, Morikawa S, Ogawa K and Ezaki T: Morphological and functional characterization of non-alcoholic fatty liver disease induced by a methionine-choline-deficient diet in C57BL/6 mice. Int J Clin Exp Pathol 6: 2683-2696, 2013.
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 2683-2696
    • Itagaki, H.1    Shimizu, K.2    Morikawa, S.3    Ogawa, K.4    Ezaki, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.