-
3
-
-
79959947008
-
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
-
Goetz JG, Minguet S, Navarro-Lerida I, Lazcano JJ, Samaniego R, Calvo E et al. Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. Cell 2011; 146: 148-163.
-
(2011)
Cell
, vol.146
, pp. 148-163
-
-
Goetz, J.G.1
Minguet, S.2
Navarro-Lerida, I.3
Lazcano, J.J.4
Samaniego, R.5
Calvo, E.6
-
4
-
-
53449094862
-
Stromal myofibroblasts are drivers of invasive cancer growth
-
De Wever O, Demetter P, Mareel M, Bracke M. Stromal myofibroblasts are drivers of invasive cancer growth. Int J Cancer 2008; 23: 2229-2238.
-
(2008)
Int J Cancer
, vol.23
, pp. 2229-2238
-
-
De Wever, O.1
Demetter, P.2
Mareel, M.3
Bracke, M.4
-
5
-
-
79952340427
-
Remodeling and homeostasis of the extracellular matrix: Implications for fibrotic diseases and cancer
-
Cox TR, Erler JT. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech 2011; 4: 165-178.
-
(2011)
Dis Model Mech
, vol.4
, pp. 165-178
-
-
Cox, T.R.1
Erler, J.T.2
-
6
-
-
33846782878
-
Collagen reorganization at the tumor-stromal interface facilitates local invasion
-
Provenzano PP, Eliceiri KW, Campbell JM, Inman DR, White JG, Keely PJ. Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med 2006; 4: 38.
-
(2006)
BMC Med
, vol.4
, pp. 38
-
-
Provenzano, P.P.1
Eliceiri, K.W.2
Campbell, J.M.3
Inman, D.R.4
White, J.G.5
Keely, P.J.6
-
7
-
-
80755173295
-
Mammographic density and breast cancer risk: Current understanding and future prospects
-
Boyd NF, Martin LJ, Yaffe M J, Minkin S. Mammographic density and breast cancer risk: current understanding and future prospects. Breast Cancer Res 2011; 13: 223.
-
(2011)
Breast Cancer Res
, vol.13
, pp. 223
-
-
Boyd, N.F.1
Martin, L.J.2
Yaffe, M.J.3
Minkin, S.4
-
8
-
-
44149123099
-
Collagen density promotes mammary tumor initiation and progression
-
Provenzano PP, Inman DR, Eliceiri KW, Knittel JG, Yan L, Reuden CT et al. Collagen density promotes mammary tumor initiation and progression. BMC Med 2008; 6: 11.
-
(2008)
BMC Med
, vol.6
, pp. 11
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Knittel, J.G.4
Yan, L.5
Reuden, C.T.6
-
9
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing Integrin Signaling
-
Levental KR, Yu H, Lakins JN, Egeblad M, Erler JT, Fong SF et al. Matrix crosslinking forces tumor progression by enhancing Integrin Signaling. Cell 2009; 139: 891-906.
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Lakins, J.N.3
Egeblad, M.4
Erler, J.T.5
Fong, S.F.6
-
11
-
-
0033060357
-
Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin
-
Thomas SM, Hagel M, Turner CE. Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin. J Cell Science 1999; 112: 181-190.
-
(1999)
J Cell Science
, vol.112
, pp. 181-190
-
-
Thomas, S.M.1
Hagel, M.2
Turner, C.E.3
-
12
-
-
51749095919
-
Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop
-
Dabiri G, Tumbarello DA, Turner CE, Van de Water L. Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop. J Invest Dermatol 2008; 128: 2518-2525.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2518-2525
-
-
Dabiri, G.1
Tumbarello, D.A.2
Turner, C.E.3
Van De Water, L.4
-
13
-
-
79551657030
-
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis
-
Deakin NO, Turner CE. Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell 2011; 22: 327-341.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 327-341
-
-
Deakin, N.O.1
Turner, C.E.2
-
14
-
-
84861325758
-
Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA
-
Deakin NO, Ballestrem C, Turner CE. Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA. PLoS One 2012; 7: e37990.
-
(2012)
PLoS One
, vol.7
, pp. e37990
-
-
Deakin, N.O.1
Ballestrem, C.2
Turner, C.E.3
-
15
-
-
0036142219
-
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
-
Hagel M, George EL, Klim A, Tamimi R, Opitz SL, Turner CE et al. The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Mol Cell Biol 2002; 22: 901-915.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 901-915
-
-
Hagel, M.1
George, E.L.2
Klim, A.3
Tamimi, R.4
Opitz, S.L.5
Turner, C.E.6
-
16
-
-
84865742470
-
Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles
-
Tchou J, Kossenkov AV, Chang L, Satija C, Herlyn M, Showe LC et al. Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles. BMC Med Genomics 2012; 5: 39.
-
(2012)
BMC Med Genomics
, vol.5
, pp. 39
-
-
Tchou, J.1
Kossenkov, A.V.2
Chang, L.3
Satija, C.4
Herlyn, M.5
Showe, L.C.6
-
17
-
-
34247637641
-
Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA / ROCK-dependent pathway
-
Tumbarello DA, Turner CE. Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA / ROCK-dependent pathway. J Cell Physiol 2007; 211: 736-748.
-
(2007)
J Cell Physiol
, vol.211
, pp. 736-748
-
-
Tumbarello, D.A.1
Turner, C.E.2
-
18
-
-
84862629472
-
Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition
-
Pignatelli J, Tumbarello DA, Schmidt RP, Turner CE. Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition. J Cell Biol 2012; 197: 421-437.
-
(2012)
J Cell Biol
, vol.197
, pp. 421-437
-
-
Pignatelli, J.1
Tumbarello, D.A.2
Schmidt, R.P.3
Turner, C.E.4
-
19
-
-
0142244181
-
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
-
Lin EY, Jones JG, Li P, Zhu L, Whitney KD, Muller WJ et al. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol 2003; 163: 2113-2126.
-
(2003)
Am J Pathol
, vol.163
, pp. 2113-2126
-
-
Lin, E.Y.1
Jones, J.G.2
Li, P.3
Zhu, L.4
Whitney, K.D.5
Muller, W.J.6
-
20
-
-
47749139256
-
Cancer as an overhealing wound: An old hypothesis revisited
-
Schäfer M, Werner S. Cancer as an overhealing wound: an old hypothesis revisited. Nat Rev Mol Cell Biol 2008; 9: 628-638.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 628-638
-
-
Schäfer, M.1
Werner, S.2
-
21
-
-
0030934532
-
Wound healing - Aiming for perfect skin regeneration
-
Martin P. Wound healing - aiming for perfect skin regeneration. Science 1997; 276: 75-81.
-
(1997)
Science
, vol.276
, pp. 75-81
-
-
Martin, P.1
-
22
-
-
33847084614
-
Formation and function of the myofibroblast during tissue repair
-
Hinz B. Formation and function of the myofibroblast during tissue repair. J Invest Dermatol 2007; 127: 526-537.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 526-537
-
-
Hinz, B.1
-
23
-
-
84859073207
-
Recent developments in myofibroblast biology: Paradigms for connective tissue remodeling
-
Hinz B, Phan SH, Thannickal VJ, Prunotto M, Desmouliere A, Varga J et al. Recent developments in myofibroblast biology: Paradigms for connective tissue remodeling. Am J Pathol 2012; 180: 1340-1355.
-
(2012)
Am J Pathol
, vol.180
, pp. 1340-1355
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Prunotto, M.4
Desmouliere, A.5
Varga, J.6
-
24
-
-
84961219361
-
Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent, MRTF-A nuclear accumulation
-
Varney SD, Betts CB, Zheng R, Wu L, Hinz B, Zhou J et al. Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent, MRTF-A nuclear accumulation. J Cell Sci 2016; 129: 774-787.
-
(2016)
J Cell Sci
, vol.129
, pp. 774-787
-
-
Varney, S.D.1
Betts, C.B.2
Zheng, R.3
Wu, L.4
Hinz, B.5
Zhou, J.6
-
25
-
-
16844374657
-
Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo
-
Kim-Kaneyama JR, Suzuki W, Ichikawa K, Ohki T, Kohno Y, Sata M et al. Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo. J Cell Sci 2005; 118: 937-949.
-
(2005)
J Cell Sci
, vol.118
, pp. 937-949
-
-
Kim-Kaneyama, J.R.1
Suzuki, W.2
Ichikawa, K.3
Ohki, T.4
Kohno, Y.5
Sata, M.6
-
26
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121: 335-348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
-
27
-
-
72049098196
-
Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage
-
Provenzano PP, Inman DR, Eliceiri KW, Keely PJ. Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage. Oncogene 2009; 28: 4326-4343.
-
(2009)
Oncogene
, vol.28
, pp. 4326-4343
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Keely, P.J.4
-
28
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek MJ, Zahir N, Johnson KR, Latkins JN, Rozenberg GI, Gefen A et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005; 8: 241-254.
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
Zahir, N.2
Johnson, K.R.3
Latkins, J.N.4
Rozenberg, G.I.5
Gefen, A.6
-
30
-
-
84883551968
-
Regulation of cell adhesion and migration by cell-derived matrices
-
Kutys ML, Doyle AD, Yamada KM. Regulation of cell adhesion and migration by cell-derived matrices. Exp Cell Res 2013; 319: 2434-2439.
-
(2013)
Exp Cell Res
, vol.319
, pp. 2434-2439
-
-
Kutys, M.L.1
Doyle, A.D.2
Yamada, K.M.3
-
31
-
-
24644466511
-
Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts
-
Amatangelo MD, Bassi DE, Klein-Szanto AJ, Cukierman E. Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts. Am J Pathol 2005; 167: 475-488.
-
(2005)
Am J Pathol
, vol.167
, pp. 475-488
-
-
Amatangelo, M.D.1
Bassi, D.E.2
Klein-Szanto, A.J.3
Cukierman, E.4
-
32
-
-
81855169565
-
Cancer invasion and the microenvironment: Plasticity and reciprocity
-
Friedl P, Alexander S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell 2011; 147: 992-1009.
-
(2011)
Cell
, vol.147
, pp. 992-1009
-
-
Friedl, P.1
Alexander, S.2
-
33
-
-
75749146306
-
Plasticity of cell migration: A multiscale tuning model
-
Friedl P, Wolf K. Plasticity of cell migration: a multiscale tuning model. J Cell Biol 2010; 188: 11-19.
-
(2010)
J Cell Biol
, vol.188
, pp. 11-19
-
-
Friedl, P.1
Wolf, K.2
-
34
-
-
84915763166
-
The extracellular matrix modulates the hallmarks of cancer
-
Pickup MW, Mouw JK, Weaver VM. The extracellular matrix modulates the hallmarks of cancer. EMBO Rep 2014; 15: 1243-1253.
-
(2014)
EMBO Rep
, vol.15
, pp. 1243-1253
-
-
Pickup, M.W.1
Mouw, J.K.2
Weaver, V.M.3
-
35
-
-
84894581126
-
Collective invasion in breast cancer requires a conserved basal epithelial program
-
Cheung KJ, Gabrielson E, Werb Z, Ewald AJ. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell 2013; 155: 1639-1651.
-
(2013)
Cell
, vol.155
, pp. 1639-1651
-
-
Cheung, K.J.1
Gabrielson, E.2
Werb, Z.3
Ewald, A.J.4
-
36
-
-
33745515023
-
Tumor microenvironment: TGFβ: The molecular jekyll and hyde of cancer
-
Bierie B, Moses HL. Tumor Microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer 2006; 6: 506-520.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
37
-
-
56649106486
-
Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55
-
Wang H, Song K, Krebs TL, Yang J, Danielpour D. Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55. Oncogene 2008; 27: 6791-6805.
-
(2008)
Oncogene
, vol.27
, pp. 6791-6805
-
-
Wang, H.1
Song, K.2
Krebs, T.L.3
Yang, J.4
Danielpour, D.5
-
38
-
-
84861416458
-
Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8
-
Shola DT, Wang H, Wahdan-Alaswad R, Danielpour D. Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8. Oncogene 2012; 31: 2480-2490.
-
(2012)
Oncogene
, vol.31
, pp. 2480-2490
-
-
Shola, D.T.1
Wang, H.2
Wahdan-Alaswad, R.3
Danielpour, D.4
-
39
-
-
59449090107
-
TGF-β-induced epithelial to mesenchymal transition
-
Xu J, Lamouille S, Derynck R. TGF-β-induced epithelial to mesenchymal transition. Cell Res 2009; 19: 156-172.
-
(2009)
Cell Res
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
40
-
-
84879468139
-
Mechanotransduction at focal adhesions: Integrating cytoskeletal mechanics in migrating cells
-
Kuo JC. Mechanotransduction at focal adhesions: integrating cytoskeletal mechanics in migrating cells. J Cell Mol Med 2013; 17: 704-712.
-
(2013)
J Cell Mol Med
, vol.17
, pp. 704-712
-
-
Kuo, J.C.1
-
41
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K et al. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007; 9: 1392-1400.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
-
42
-
-
84857640591
-
Cancer associated fibroblasts: The dark side of the coin
-
Cirri P, Chiarugi P. Cancer associated fibroblasts: the dark side of the coin. Am J Cancer Res 2011; 1: 482-497.
-
(2011)
Am J Cancer Res
, vol.1
, pp. 482-497
-
-
Cirri, P.1
Chiarugi, P.2
-
43
-
-
84859949610
-
The extracellular matrix: A dynamic niche in cancer progression
-
Lu P, Weaver VM, Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 2012; 196: 395-406.
-
(2012)
J Cell Biol
, vol.196
, pp. 395-406
-
-
Lu, P.1
Weaver, V.M.2
Werb, Z.3
-
44
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002; 2: 161-174.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
45
-
-
84939461863
-
Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms
-
Lei XF, Kim-Kaneyama JR, Arita-Okubo S, Offermanns S, Itabe H, Miyazaki T et al. Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms. J Am Heart Assoc 2014; 3: e000747.
-
(2014)
J Am Heart Assoc
, vol.3
, pp. e000747
-
-
Lei, X.F.1
Kim-Kaneyama, J.R.2
Arita-Okubo, S.3
Offermanns, S.4
Itabe, H.5
Miyazaki, T.6
-
46
-
-
84964344000
-
Focal adhesions, stress fibers and mechanical tension
-
Burridge K, Guilluy C. Focal adhesions, stress fibers and mechanical tension. Exp Cell Res 2016; 343: 14-20.
-
(2016)
Exp Cell Res
, vol.343
, pp. 14-20
-
-
Burridge, K.1
Guilluy, C.2
-
47
-
-
0034940161
-
Hic-5-reduced cell spreading on fibronectin: Competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase
-
Nishiya N, Tachibana K, Shibanuma M, Mashimo JI, Nose K. Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase. Mol Cell Biol 2001; 21: 5332-5345.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5332-5345
-
-
Nishiya, N.1
Tachibana, K.2
Shibanuma, M.3
Mashimo, J.I.4
Nose, K.5
-
49
-
-
84979920428
-
Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation
-
e-pub ahead of print 17 June
-
Ouderkirk-Pecone JL, Goreczny GJ, Chase SE, Tatum AH, Turner CE, Krendel M. Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation. Oncotarget; e-pub ahead of print 17 June 2016; doi:10.18632/oncotarget.10139.
-
(2016)
Oncotarget
-
-
Ouderkirk-Pecone, J.L.1
Goreczny, G.J.2
Chase, S.E.3
Tatum, A.H.4
Turner, C.E.5
Krendel, M.6
-
50
-
-
80355131580
-
Evaluation of mammary gland development and function in mouse models
-
Plante I, Stewart MK, Laird DW. Evaluation of mammary gland development and function in mouse models. JoVE 2011; 53: pii: 2828.
-
(2011)
JoVE
, vol.53
-
-
Plante, I.1
Stewart, M.K.2
Laird, D.W.3
-
51
-
-
84921859100
-
3D culture assays of murine mammary branching morphogenesis and epithelial invasion
-
Nguyen-Ngoc KV, Shamir ER, Huebner RJ, Beck JN, Cheung KJ, Ewald AJ. 3D culture assays of murine mammary branching morphogenesis and epithelial invasion. Methods Mol Biol 2015; 1189: 135-162.
-
(2015)
Methods Mol Biol
, vol.1189
, pp. 135-162
-
-
Nguyen-Ngoc, K.V.1
Shamir, E.R.2
Huebner, R.J.3
Beck, J.N.4
Cheung, K.J.5
Ewald, A.J.6
-
52
-
-
84861095232
-
Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy
-
Rezakhaniha R, Agianniotis A, Schrauwen JT, Griffa A, Sage D, Bouten CV et al. Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy. Biomech Model Mechanobiol 2012; 11: 461-473.
-
(2012)
Biomech Model Mechanobiol
, vol.11
, pp. 461-473
-
-
Rezakhaniha, R.1
Agianniotis, A.2
Schrauwen, J.T.3
Griffa, A.4
Sage, D.5
Bouten, C.V.6
|