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Volumn 136, Issue 12, 2016, Pages 2417-2426

Epidermal Mineralocorticoid Receptor Plays Beneficial and Adverse Effects in Skin and Mediates Glucocorticoid Responses

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MINERALOCORTICOID RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; GLUCOCORTICOID RECEPTOR;

EID: 84997254240     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1016/j.jid.2016.07.018     Document Type: Article
Times cited : (30)

References (47)
  • 1
    • 84921599010 scopus 로고    scopus 로고
    • Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases
    • Bauersachs, J., Jaisser, F., Toto, R., Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases. Hypertension 65 (2015), 257–263.
    • (2015) Hypertension , vol.65 , pp. 257-263
    • Bauersachs, J.1    Jaisser, F.2    Toto, R.3
  • 2
    • 0033628284 scopus 로고    scopus 로고
    • Glucocorticoid-regulated gene expression during cutaneous wound repair
    • Beer, H.D., Fässler, R., Werner, S., Glucocorticoid-regulated gene expression during cutaneous wound repair. Vitam Horm 59 (2000), 217–239.
    • (2000) Vitam Horm , vol.59 , pp. 217-239
    • Beer, H.D.1    Fässler, R.2    Werner, S.3
  • 5
    • 74949137472 scopus 로고    scopus 로고
    • Aldosterone abrogates nuclear factor kappaB-mediated tumor necrosis factor alpha production in human neutrophils via the mineralocorticoid receptor
    • Bergmann, A., Eulenberg, C., Wellner, M., Rolle, S., Luft, F., Kettritz, R., Aldosterone abrogates nuclear factor kappaB-mediated tumor necrosis factor alpha production in human neutrophils via the mineralocorticoid receptor. Hypertension 55 (2010), 370–379.
    • (2010) Hypertension , vol.55 , pp. 370-379
    • Bergmann, A.1    Eulenberg, C.2    Wellner, M.3    Rolle, S.4    Luft, F.5    Kettritz, R.6
  • 6
    • 84953910769 scopus 로고    scopus 로고
    • The mineralocorticoid receptor plays a transient role in mouse skin development
    • Boix, J., Carceller, E., Sevilla, L.M., Marcos-Garcés, V., Pérez, P., The mineralocorticoid receptor plays a transient role in mouse skin development. Exp Dermatol 25 (2015), 69–71.
    • (2015) Exp Dermatol , vol.25 , pp. 69-71
    • Boix, J.1    Carceller, E.2    Sevilla, L.M.3    Marcos-Garcés, V.4    Pérez, P.5
  • 7
    • 84880922018 scopus 로고    scopus 로고
    • Contribution of aldosterone to cardiovascular and renal inflammation and fibrosis
    • Brown, N., Contribution of aldosterone to cardiovascular and renal inflammation and fibrosis. Nat Rev Nephrol 9 (2013), 459–469.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 459-469
    • Brown, N.1
  • 8
    • 84875237427 scopus 로고    scopus 로고
    • The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore
    • Busillo, J.M., Cidlowski, J.A., The five Rs of glucocorticoid action during inflammation: ready, reinforce, repress, resolve, and restore. Trends Endocrinol Metab 24 (2013), 109–119.
    • (2013) Trends Endocrinol Metab , vol.24 , pp. 109-119
    • Busillo, J.M.1    Cidlowski, J.A.2
  • 9
    • 18844446729 scopus 로고    scopus 로고
    • Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia
    • Cascallana, J.L., Bravo, A., Donet, E., Leis, H., Lara, M.F., Paramio, J.M., et al. Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia. Endocrinology 146 (2005), 2629–2638.
    • (2005) Endocrinology , vol.146 , pp. 2629-2638
    • Cascallana, J.L.1    Bravo, A.2    Donet, E.3    Leis, H.4    Lara, M.F.5    Paramio, J.M.6
  • 10
    • 8844234951 scopus 로고    scopus 로고
    • The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy
    • Cato, A.C., Schäcke, H., Sterry, W., Asadullah, K., The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy. Curr Drug Targets Inflamm Allergy 3 (2004), 347–355.
    • (2004) Curr Drug Targets Inflamm Allergy , vol.3 , pp. 347-355
    • Cato, A.C.1    Schäcke, H.2    Sterry, W.3    Asadullah, K.4
  • 11
    • 74949094864 scopus 로고    scopus 로고
    • The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?
    • Farman, N., Maubec, E., Poeggeler, B., Klatte, J.E., Jaisser, F., Paus, R., The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?. Exp Dermatol 19 (2010), 100–107.
    • (2010) Exp Dermatol , vol.19 , pp. 100-107
    • Farman, N.1    Maubec, E.2    Poeggeler, B.3    Klatte, J.E.4    Jaisser, F.5    Paus, R.6
  • 12
    • 84953897659 scopus 로고    scopus 로고
    • A novel actor in skin biology: the mineralocorticoid receptor
    • Farman, N., Nguyen, V.T., A novel actor in skin biology: the mineralocorticoid receptor. Exp Dermatol 25 (2015), 24–25.
    • (2015) Exp Dermatol , vol.25 , pp. 24-25
    • Farman, N.1    Nguyen, V.T.2
  • 13
    • 78049492323 scopus 로고    scopus 로고
    • Minireview: aldosterone and mineralocorticoid receptors: past, present, and future
    • Funder, J.W., Minireview: aldosterone and mineralocorticoid receptors: past, present, and future. Endocrinology 151 (2010), 5098–5102.
    • (2010) Endocrinology , vol.151 , pp. 5098-5102
    • Funder, J.W.1
  • 14
    • 84908695226 scopus 로고    scopus 로고
    • The multifaceted mineralocorticoid receptor
    • Gomez-Sanchez, E., Gomez-Sanchez, C.E., The multifaceted mineralocorticoid receptor. Compr Physiol 4 (2014), 965–994.
    • (2014) Compr Physiol , vol.4 , pp. 965-994
    • Gomez-Sanchez, E.1    Gomez-Sanchez, C.E.2
  • 15
    • 84954233101 scopus 로고    scopus 로고
    • Third-generation mineralocorticoid receptor antagonists: why do we need a fourth?
    • Gomez-Sanchez, E.P., Third-generation mineralocorticoid receptor antagonists: why do we need a fourth?. J Cardiovasc Pharmacol 67 (2016), 26–38.
    • (2016) J Cardiovasc Pharmacol , vol.67 , pp. 26-38
    • Gomez-Sanchez, E.P.1
  • 16
    • 0018865014 scopus 로고
    • Calcium regulation of growth and differentiation of mouse epidermal cells in culture
    • Hennings, H., Michael, D., Cheng, C., Steinert, P., Holbrook, K., Yuspa, S.H., Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19 (1980), 245–254.
    • (1980) Cell , vol.19 , pp. 245-254
    • Hennings, H.1    Michael, D.2    Cheng, C.3    Steinert, P.4    Holbrook, K.5    Yuspa, S.H.6
  • 17
    • 84955055595 scopus 로고    scopus 로고
    • Emerging roles of the mineralocorticoid receptor in pathology: toward new paradigms in clinical pharmacology
    • Jaisser, F., Farman, N., Emerging roles of the mineralocorticoid receptor in pathology: toward new paradigms in clinical pharmacology. Pharmacol Rev 68 (2016), 49–75.
    • (2016) Pharmacol Rev , vol.68 , pp. 49-75
    • Jaisser, F.1    Farman, N.2
  • 18
    • 0028153108 scopus 로고
    • Human skin as target for aldosterone: coexpression of mineralocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase
    • Kenouch, S., Lombes, M., Delahaye, F., Eugene, E., Bonvalet, J.P., Farman, N., Human skin as target for aldosterone: coexpression of mineralocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase. J Clin Endocrinol Metab 79 (1994), 1334–1341.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1334-1341
    • Kenouch, S.1    Lombes, M.2    Delahaye, F.3    Eugene, E.4    Bonvalet, J.P.5    Farman, N.6
  • 20
    • 84887819122 scopus 로고    scopus 로고
    • Selective ablation of glucocorticoid receptor in mouse keratinocytes increases susceptibility to skin tumorigenesis
    • Latorre, V., Sevilla, L.M., Sanchis, A., Pérez, P., Selective ablation of glucocorticoid receptor in mouse keratinocytes increases susceptibility to skin tumorigenesis. J Invest Dermatol 133 (2013), 2771–2779.
    • (2013) J Invest Dermatol , vol.133 , pp. 2771-2779
    • Latorre, V.1    Sevilla, L.M.2    Sanchis, A.3    Pérez, P.4
  • 21
    • 84888113464 scopus 로고    scopus 로고
    • Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRg activation
    • Leung, W.H., Vong, Q.P., Lin, W., Janke, L., Chen, T., Leung, W., Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRg activation. J Exp Med 210 (2013), 2675–2692.
    • (2013) J Exp Med , vol.210 , pp. 2675-2692
    • Leung, W.H.1    Vong, Q.P.2    Lin, W.3    Janke, L.4    Chen, T.5    Leung, W.6
  • 22
    • 84872823274 scopus 로고    scopus 로고
    • The mineralocorticoid signaling pathway throughout development: expression, regulation and pathophysiological implications
    • Martinerie, L., Munier, M., Menuet, D.L., Meduri, G., Viengchareun, S., Lombès, M., The mineralocorticoid signaling pathway throughout development: expression, regulation and pathophysiological implications. Biochimie 95 (2013), 148–157.
    • (2013) Biochimie , vol.95 , pp. 148-157
    • Martinerie, L.1    Munier, M.2    Menuet, D.L.3    Meduri, G.4    Viengchareun, S.5    Lombès, M.6
  • 24
    • 68549109739 scopus 로고    scopus 로고
    • Cardiac aldosterone overexpression prevents harmful effects of diabetes in the mouse heart by preserving capillary density
    • Messaoudi, S., Milliez, P., Samuel, J.L., Delcayre, C., Cardiac aldosterone overexpression prevents harmful effects of diabetes in the mouse heart by preserving capillary density. FASEB J 23 (2009), 2176–2185.
    • (2009) FASEB J , vol.23 , pp. 2176-2185
    • Messaoudi, S.1    Milliez, P.2    Samuel, J.L.3    Delcayre, C.4
  • 25
    • 77956883402 scopus 로고    scopus 로고
    • Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin
    • Mitts, T.F., Bunda, S., Wang, Y., Hinek, A., Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin. J Invest Dermatol 130 (2010), 2396–2406.
    • (2010) J Invest Dermatol , vol.130 , pp. 2396-2406
    • Mitts, T.F.1    Bunda, S.2    Wang, Y.3    Hinek, A.4
  • 26
    • 84872595536 scopus 로고    scopus 로고
    • Aging-like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling
    • Nagase, T., Akase, T., Sanada, H., Minematsu, T., Ibuki, A., Huang, L., et al. Aging-like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling. Aging Cell 12 (2013), 50–57.
    • (2013) Aging Cell , vol.12 , pp. 50-57
    • Nagase, T.1    Akase, T.2    Sanada, H.3    Minematsu, T.4    Ibuki, A.5    Huang, L.6
  • 27
    • 84887016715 scopus 로고    scopus 로고
    • The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease
    • Oakley, R.H., Cidlowski, J.A., The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease. J Allergy Clin Immunol 132 (2013), 1033–1044.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 1033-1044
    • Oakley, R.H.1    Cidlowski, J.A.2
  • 28
    • 84941261196 scopus 로고    scopus 로고
    • Glucocorticoid signaling in the heart: a cardiomyocyte perspective
    • Oakley, R.H., Cidlowski, J.A., Glucocorticoid signaling in the heart: a cardiomyocyte perspective. J Steroid Biochem Mol Biol 153 (2015), 27–34.
    • (2015) J Steroid Biochem Mol Biol , vol.153 , pp. 27-34
    • Oakley, R.H.1    Cidlowski, J.A.2
  • 29
    • 58549091475 scopus 로고    scopus 로고
    • Mineralocorticoid receptors: emerging complexity and functional diversity
    • Odermatt, A., Atanasov, A.G., Mineralocorticoid receptors: emerging complexity and functional diversity. Steroids 74 (2009), 163–171.
    • (2009) Steroids , vol.74 , pp. 163-171
    • Odermatt, A.1    Atanasov, A.G.2
  • 31
    • 0035464779 scopus 로고    scopus 로고
    • Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor
    • Pérez, P., Page, A., Bravo, A., del Río, M., Gimenez-Conti, I., Budunova, I., et al. Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor. FASEB J 15 (2001), 2030–2036.
    • (2001) FASEB J , vol.15 , pp. 2030-2036
    • Pérez, P.1    Page, A.2    Bravo, A.3    del Río, M.4    Gimenez-Conti, I.5    Budunova, I.6
  • 32
    • 80054041991 scopus 로고    scopus 로고
    • Glucocorticoid receptors, epidermal homeostasis and hair follicle differentiation
    • Pérez, P., Glucocorticoid receptors, epidermal homeostasis and hair follicle differentiation. Dermatoendocrinology 3 (2011), 1–9.
    • (2011) Dermatoendocrinology , vol.3 , pp. 1-9
    • Pérez, P.1
  • 33
    • 0034086224 scopus 로고    scopus 로고
    • Novel mechanism of steroid action in skin through glucocorticoid receptor monomers
    • Radoja, N., Komine, M., Jho, S.H., Blumenberg, M., Tomic-Canic, M., Novel mechanism of steroid action in skin through glucocorticoid receptor monomers. Mol Cell Biol 20 (2000), 4328–4339.
    • (2000) Mol Cell Biol , vol.20 , pp. 4328-4339
    • Radoja, N.1    Komine, M.2    Jho, S.H.3    Blumenberg, M.4    Tomic-Canic, M.5
  • 34
    • 2942582215 scopus 로고    scopus 로고
    • A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination
    • Ramírez, A., Page, A., Gandarillas, A., Zanet, J., Pibre, S., Vidal, M., et al. A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination. Genesis 39 (2004), 52–57.
    • (2004) Genesis , vol.39 , pp. 52-57
    • Ramírez, A.1    Page, A.2    Gandarillas, A.3    Zanet, J.4    Pibre, S.5    Vidal, M.6
  • 35
    • 84949754523 scopus 로고    scopus 로고
    • GILZ as a mediator of the anti-inflammatory effects of glucocorticoids
    • Ronchetti, S., Migliorati, G., Riccardi, C., GILZ as a mediator of the anti-inflammatory effects of glucocorticoids. Front Endocrinol, 6, 2015, 170.
    • (2015) Front Endocrinol , vol.6 , pp. 170
    • Ronchetti, S.1    Migliorati, G.2    Riccardi, C.3
  • 36
    • 34548844449 scopus 로고    scopus 로고
    • Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia
    • Sainte Marie, Y., Toulon, A., Paus, R., Maubec, E., Cherfa, A., Grossin, M., et al. Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia. Am J Pathol 171 (2007), 846–860.
    • (2007) Am J Pathol , vol.171 , pp. 846-860
    • Sainte Marie, Y.1    Toulon, A.2    Paus, R.3    Maubec, E.4    Cherfa, A.5    Grossin, M.6
  • 37
    • 84855374132 scopus 로고    scopus 로고
    • Keratinocyte-targeted overexpression of the glucocorticoid receptor delays cutaneous wound healing
    • Sanchis, A., Alba, L., Latorre, V., Sevilla, L.M., Pérez, P., Keratinocyte-targeted overexpression of the glucocorticoid receptor delays cutaneous wound healing. PLoS One, 7, 2012, e29701.
    • (2012) PLoS One , vol.7 , pp. e29701
    • Sanchis, A.1    Alba, L.2    Latorre, V.3    Sevilla, L.M.4    Pérez, P.5
  • 38
    • 0036810356 scopus 로고    scopus 로고
    • Mechanisms involved in the side effects of glucocorticoids
    • Schäcke, H., Döcke, W.D., Asadullah, K., Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 96 (2002), 23–43.
    • (2002) Pharmacol Ther , vol.96 , pp. 23-43
    • Schäcke, H.1    Döcke, W.D.2    Asadullah, K.3
  • 39
    • 84939469252 scopus 로고    scopus 로고
    • Glucocorticoid receptor and klf4 co-regulate anti-inflammatory genes in keratinocytes
    • Sevilla, L.M., Latorre, V., Carceller, E., Boix, J., Vodak, D., Mills, I.G., et al. Glucocorticoid receptor and klf4 co-regulate anti-inflammatory genes in keratinocytes. Mol Cell Endocrinol 412 (2015), 281–289.
    • (2015) Mol Cell Endocrinol , vol.412 , pp. 281-289
    • Sevilla, L.M.1    Latorre, V.2    Carceller, E.3    Boix, J.4    Vodak, D.5    Mills, I.G.6
  • 40
    • 84872605849 scopus 로고    scopus 로고
    • Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation
    • Sevilla, L.M., Latorre, V., Sanchis, A., Pérez, P., Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation. J Invest Dermatol 33 (2013), 361–370.
    • (2013) J Invest Dermatol , vol.33 , pp. 361-370
    • Sevilla, L.M.1    Latorre, V.2    Sanchis, A.3    Pérez, P.4
  • 41
    • 84901490008 scopus 로고    scopus 로고
    • Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity
    • Slominski, A.T., Manna, P.R., Tuckey, R.C., Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity. Exp Dermatol 23 (2014), 369–374.
    • (2014) Exp Dermatol , vol.23 , pp. 369-374
    • Slominski, A.T.1    Manna, P.R.2    Tuckey, R.C.3
  • 42
    • 21244437594 scopus 로고    scopus 로고
    • Molecular pathogenesis of chronic wounds: the role of beta-catenin and c-myc in the inhibition of epithelialization and wound healing
    • Stojadinovic, O., Brem, H., Vouthounis, C., Lee, B., Fallon, J., Stallcup, M., et al. Molecular pathogenesis of chronic wounds: the role of beta-catenin and c-myc in the inhibition of epithelialization and wound healing. Am J Pathol 167 (2005), 59–69.
    • (2005) Am J Pathol , vol.167 , pp. 59-69
    • Stojadinovic, O.1    Brem, H.2    Vouthounis, C.3    Lee, B.4    Fallon, J.5    Stallcup, M.6
  • 43
    • 84879638689 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects
    • Tiganescu, A., Tahrani, A.A., Morgan, S.A., Otranto, M., Desmoulière, A., Abrahams, L., et al. 11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects. J Clin Invest 123 (2013), 3051–3060.
    • (2013) J Clin Invest , vol.123 , pp. 3051-3060
    • Tiganescu, A.1    Tahrani, A.A.2    Morgan, S.A.3    Otranto, M.4    Desmoulière, A.5    Abrahams, L.6
  • 44
    • 84874585409 scopus 로고    scopus 로고
    • New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation
    • Vandevyver, S., Dejager, L., Tuckermann, J., Libert, C., New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation. Endocrinology 154 (2013), 993–1007.
    • (2013) Endocrinology , vol.154 , pp. 993-1007
    • Vandevyver, S.1    Dejager, L.2    Tuckermann, J.3    Libert, C.4
  • 47
    • 84883490770 scopus 로고    scopus 로고
    • Local blockade of glucocorticoid activation reverses stress- and glucocorticoid-induced delays in cutaneous wound healing
    • Youm, J.K., Park, K., Uchida, Y., Chan, A., Mauro, T.M., Holleran, W.M., et al. Local blockade of glucocorticoid activation reverses stress- and glucocorticoid-induced delays in cutaneous wound healing. Wound Repair Regen 21 (2013), 715–722.
    • (2013) Wound Repair Regen , vol.21 , pp. 715-722
    • Youm, J.K.1    Park, K.2    Uchida, Y.3    Chan, A.4    Mauro, T.M.5    Holleran, W.M.6


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