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Volumn 135, Issue 7, 2015, Pages 1781-1789

Topical mineralocorticoid receptor blockade limits glucocorticoid-induced epidermal atrophy in human skin

(20)  Maubec, Eve a,b   Laouénan, Cédric a,b,c   Deschamps, Lydia a   Nguyen, Van Tuan d,e   Scheer Senyarich, Isabelle a   Wackenheim Jacobs, Anne Catherine a   Steff, Maud a,b   Duhamel, Stéphanie e,f   Tubiana, Sarah a,b,c   Brahimi, Nesrine a   Leclerc Mercier, Stéphanie g   Crickx, Béatrice a,b   Perret, Claudine e,f   Aractingi, Selim b,h   Escoubet, Brigitte a,b,f   Duval, Xavier a,b,c   Arnaud, Philippe a,b,i,j   Jaisser, Frederic e,f   Mentré, France a,b,c   Farman, Nicolette e,f  

i CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CANRENOIC ACID; CLOBETASOL; EPITHELIAL SODIUM CHANNEL; MINERALOCORTICOID RECEPTOR; PHENAMIL; PLACEBO; SPIRONOLACTONE; GLUCOCORTICOID; MINERALOCORTICOID ANTAGONIST;

EID: 84931063566     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.44     Document Type: Article
Times cited : (43)

References (47)
  • 1
    • 84873027749 scopus 로고    scopus 로고
    • Mineralocorticoid receptormediated vascular insulin resistance: An early contributor to diabetesrelated vascular disease?
    • Bender SB, McGraw AP, Jaffe IZ, et al. (2013) Mineralocorticoid receptormediated vascular insulin resistance: an early contributor to diabetesrelated vascular disease?. Diabetes 62:313-9
    • (2013) Diabetes , vol.62 , pp. 313-319
    • Bender, S.B.1    McGraw, A.P.2    Jaffe, I.Z.3
  • 2
    • 0032704935 scopus 로고    scopus 로고
    • Epithelial sodium channel in human epidermal keratinocytes: Expression of its subunits and relation to sodium transport and differentiation
    • Brouard M, Casado M, Djelidi S, et al. (1999) Epithelial sodium channel in human epidermal keratinocytes: expression of its subunits and relation to sodium transport and differentiation. J Cell Sci 112: 3343-52
    • (1999) J Cell Sci , vol.112 , pp. 3343-3352
    • Brouard, M.1    Casado, M.2    Djelidi, S.3
  • 3
    • 33748448077 scopus 로고    scopus 로고
    • Evaluation of the atrophogenic potential of different glucocorticoids using optical coherence tomography, 20-MHz ultrasound and profilometry; A double-blind, placebo-controlled trial
    • Cossmann M, Welzel J. (2006) Evaluation of the atrophogenic potential of different glucocorticoids using optical coherence tomography, 20-MHz ultrasound and profilometry; a double-blind, placebo-controlled trial. Br J Dermatol 155:700-6
    • (2006) Br J Dermatol , vol.155 , pp. 700-706
    • Cossmann, M.1    Welzel, J.2
  • 4
    • 77955274594 scopus 로고    scopus 로고
    • Targeting inflammation using selective glucocorticoid receptor modulators
    • De Bosscher K, Haegeman G, Elewaut D. (2010) Targeting inflammation using selective glucocorticoid receptor modulators. Curr Opin Pharmacol 10: 497-504
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 497-504
    • De Bosscher, K.1    Haegeman, G.2    Elewaut, D.3
  • 5
    • 77956909015 scopus 로고    scopus 로고
    • A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule
    • Fagart J, Hillisch A, Huyet J, et al. (2010) A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule. J Biol Chem 285:29932-40
    • (2010) J Biol Chem , vol.285 , pp. 29932-29940
    • Fagart, J.1    Hillisch, A.2    Huyet, J.3
  • 6
    • 74949094864 scopus 로고    scopus 로고
    • The mineralocorticoid receptor as a novel player in skin biology: Beyond the renal horizon?
    • Farman N, Maubec E, Poeggeler B, et al. (2010) The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?. Exp Dermatol 19:100-7
    • (2010) Exp Dermatol , vol.19 , pp. 100-107
    • Farman, N.1    Maubec, E.2    Poeggeler, B.3
  • 8
    • 32644432179 scopus 로고    scopus 로고
    • Development of a panel of monoclonal antibodies against the mineralocorticoid receptor
    • Gomez-Sanchez CE, de Rodriguez AF, Romero DG, et al. (2006) Development of a panel of monoclonal antibodies against the mineralocorticoid receptor. Endocrinology 147:1343-8
    • (2006) Endocrinology , vol.147 , pp. 1343-1348
    • Gomez-Sanchez, C.E.1    De Rodriguez, A.F.2    Romero, D.G.3
  • 9
    • 53849143575 scopus 로고    scopus 로고
    • Tissue-specific glucocorticoid action: A family affair
    • Gross KL, Cidlowski JA. (2008) Tissue-specific glucocorticoid action: a family affair. Trends Endocrinol Metab 19:331-9
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 331-339
    • Gross, K.L.1    Cidlowski, J.A.2
  • 10
    • 34247203651 scopus 로고    scopus 로고
    • Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure
    • Guder G, Bauersachs J, Frantz S, et al. (2007) Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure. Circulation 115:1754-61
    • (2007) Circulation , vol.115 , pp. 1754-1761
    • Guder, G.1    Bauersachs, J.2    Frantz, S.3
  • 11
    • 2342519384 scopus 로고    scopus 로고
    • A nonconventional look at ionic fluxes in the skin: Lessons from genetically modified mice
    • Guitard M, Leyvraz C, Hummler E. (2004) A nonconventional look at ionic fluxes in the skin: lessons from genetically modified mice. News Physiol Sci 19:75-9
    • (2004) News Physiol Sci , vol.19 , pp. 75-79
    • Guitard, M.1    Leyvraz, C.2    Hummler, E.3
  • 12
    • 33751236177 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus
    • Guo C, Martinez-Vasquez D, Mendez GP, et al. (2006) Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology 147:5363-73
    • (2006) Endocrinology , vol.147 , pp. 5363-5373
    • Guo, C.1    Martinez-Vasquez, D.2    Mendez, G.P.3
  • 13
    • 23444462244 scopus 로고    scopus 로고
    • Human hair follicles display a functional equivalent of the hypothalamic-pituitary-Adrenal axis and synthesize cortisol
    • Ito N, Ito T, Kromminga A, et al. (2005) Human hair follicles display a functional equivalent of the hypothalamic-pituitary-Adrenal axis and synthesize cortisol. FASEB J 19:1332-4
    • (2005) FASEB J , vol.19 , pp. 1332-1334
    • Ito, N.1    Ito, T.2    Kromminga, A.3
  • 14
    • 0028153108 scopus 로고
    • Human skin as target for aldosterone: Coexpression of mineralocorticoid receptors and 11 betahydroxysteroid dehydrogenase
    • Kenouch S, Lombes M, Delahaye F, et al. (1994) Human skin as target for aldosterone: coexpression of mineralocorticoid receptors and 11 betahydroxysteroid dehydrogenase. J Clin Endocrinol Metab 79:1334-41
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1334-1341
    • Kenouch, S.1    Lombes, M.2    Delahaye, F.3
  • 15
    • 84856337738 scopus 로고    scopus 로고
    • Molecular pharmacology of the mineralocorticoid receptor: Prospects for novel therapeutics
    • Kolkhof P, Borden SA. (2012) Molecular pharmacology of the mineralocorticoid receptor: prospects for novel therapeutics. Mol Cell Endocrinol 350:310-7
    • (2012) Mol Cell Endocrinol , vol.350 , pp. 310-317
    • Kolkhof, P.1    Borden, S.A.2
  • 16
    • 80155151956 scopus 로고    scopus 로고
    • Aldosterone, mineralocorticoid receptor activation, and cardiovascular remodeling
    • Leopold JA. (2011) Aldosterone, mineralocorticoid receptor activation, and cardiovascular remodeling. Circulation 124:e466-8
    • (2011) Circulation , vol.124 , pp. e466-e468
    • Leopold, J.A.1
  • 17
    • 77649106201 scopus 로고    scopus 로고
    • Aldosterone receptor antagonists: Effective but often forgotten
    • Maron BA, Leopold JA. (2010) Aldosterone receptor antagonists: effective but often forgotten. Circulation 121:934-9
    • (2010) Circulation , vol.121 , pp. 934-939
    • Maron, B.A.1    Leopold, J.A.2
  • 18
    • 0036231566 scopus 로고    scopus 로고
    • The ENaC channel is required for normal epidermal differentiation
    • Mauro T, Guitard M, Behne M, et al. (2002) The ENaC channel is required for normal epidermal differentiation. J Invest Dermatol 118:589-94
    • (2002) J Invest Dermatol , vol.118 , pp. 589-594
    • Mauro, T.1    Guitard, M.2    Behne, M.3
  • 19
    • 73349119698 scopus 로고    scopus 로고
    • Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction
    • Mihailidou AS, Loan Le TY, Mardini M, et al. (2009) Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction. Hypertension 54:1306-12
    • (2009) Hypertension , vol.54 , pp. 1306-1312
    • Mihailidou, A.S.1    Loan Le, T.Y.2    Mardini, M.3
  • 20
    • 38149020049 scopus 로고    scopus 로고
    • Enhanced expression of mineralocorticoid receptors in the heart after the myocardial infarct in rats
    • Milik E, Szczepanska-Sadowska E, Maslinski W, et al. (2007) Enhanced expression of mineralocorticoid receptors in the heart after the myocardial infarct in rats. J Physiol Pharmacol 58:745-55
    • (2007) J Physiol Pharmacol , vol.58 , pp. 745-755
    • Milik, E.1    Szczepanska-Sadowska, E.2    Maslinski, W.3
  • 21
    • 77956883402 scopus 로고    scopus 로고
    • Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin
    • Mitts TF, Bunda S, Wang Y, et al. (2010) Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin. J Invest Dermatol 130:2396-406
    • (2010) J Invest Dermatol , vol.130 , pp. 2396-2406
    • Mitts, T.F.1    Bunda, S.2    Wang, Y.3
  • 22
    • 84872595536 scopus 로고    scopus 로고
    • Aging-like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling
    • Nagase T, Akase T, Sanada H, et al. (2013) Aging-like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling. Aging Cell 12:50-7
    • (2013) Aging Cell , vol.12 , pp. 50-57
    • Nagase, T.1    Akase, T.2    Sanada, H.3
  • 24
    • 80054041991 scopus 로고    scopus 로고
    • Glucocorticoid receptors, epidermal homeostasis and hair follicle differentiation
    • Perez P. (2011) Glucocorticoid receptors, epidermal homeostasis and hair follicle differentiation. Dermatoendocrinol 3:166-74
    • (2011) Dermatoendocrinol , vol.3 , pp. 166-174
    • Perez, P.1
  • 25
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B, Remme W, Zannad F, et al. (2003) Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 348:1309-21
    • (2003) N Engl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3
  • 26
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, et al. (1999) The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341:709-17
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 27
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids-new mechanisms for old drugs
    • Rhen T, Cidlowski JA. (2005) Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 353:1711-23
    • (2005) N Engl J Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 28
    • 34548844449 scopus 로고    scopus 로고
    • Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia
    • Sainte Marie Y, Toulon A, Paus R, et al. (2007) Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia. Am J Pathol 171:846-60
    • (2007) Am J Pathol , vol.171 , pp. 846-860
    • Sainte Marie, Y.1    Toulon, A.2    Paus, R.3
  • 29
    • 34547887674 scopus 로고    scopus 로고
    • Selective glucocorticoid receptor agonists (SEGRAs): Novel ligands with an improved therapeutic index
    • Schacke H, Berger M, Rehwinkel H, et al. (2007) Selective glucocorticoid receptor agonists (SEGRAs): novel ligands with an improved therapeutic index. Mol Cell Endocrinol 275:109-17
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 109-117
    • Schacke, H.1    Berger, M.2    Rehwinkel, H.3
  • 30
    • 0347719371 scopus 로고    scopus 로고
    • Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
    • Schacke H, Schottelius A, Docke WD, et al. (2004) Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects. Proc Natl Acad Sci USA 101:227-32
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 227-232
    • Schacke, H.1    Schottelius, A.2    Docke, W.D.3
  • 31
    • 33646531178 scopus 로고    scopus 로고
    • Glucocorticoid therapy-induced skin atrophy
    • Schoepe S, Schacke H, May E, et al. (2006) Glucocorticoid therapy-induced skin atrophy. Exp Dermatol 15:406-20
    • (2006) Exp Dermatol , vol.15 , pp. 406-420
    • Schoepe, S.1    Schacke, H.2    May, E.3
  • 32
    • 84860367978 scopus 로고    scopus 로고
    • Aldosterone blockade and the mineralocorticoid receptor in the management of chronic kidney disease: Current concepts and emerging treatment paradigms
    • Shavit L, Lifschitz MD, Epstein M. (2012) Aldosterone blockade and the mineralocorticoid receptor in the management of chronic kidney disease: current concepts and emerging treatment paradigms. Kidney Int 81:955-68
    • (2012) Kidney Int , vol.81 , pp. 955-968
    • Shavit, L.1    Lifschitz, M.D.2    Epstein, M.3
  • 33
    • 0029941924 scopus 로고    scopus 로고
    • ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin
    • Slominski A, Ermak G, Mihm M. (1996) ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. J Clin Endocrinol Metab 81:2746-9
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2746-2749
    • Slominski, A.1    Ermak, G.2    Mihm, M.3
  • 34
    • 0032782128 scopus 로고    scopus 로고
    • Metabolism of progesterone to DOC, corticosterone and 18OHDOC in cultured human melanoma cells
    • Slominski A, Gomez-Sanchez CE, Foecking MF, et al. (1999) Metabolism of progesterone to DOC, corticosterone and 18OHDOC in cultured human melanoma cells. FEBS Lett 455:364-6
    • (1999) FEBS Lett , vol.455 , pp. 364-366
    • Slominski, A.1    Gomez-Sanchez, C.E.2    Foecking, M.F.3
  • 35
    • 84886601180 scopus 로고    scopus 로고
    • Steroidogenesis in the skin: Implications for local immune functions
    • Slominski A, Zbytek B, Nikolakis G, et al. (2013a) Steroidogenesis in the skin: implications for local immune functions. J Steroid Biochem Mol Biol 137: 107-23
    • (2013) J Steroid Biochem Mol Biol , vol.137 , pp. 107-123
    • Slominski, A.1    Zbytek, B.2    Nikolakis, G.3
  • 36
    • 17044374014 scopus 로고    scopus 로고
    • CRH stimulates POMC activity and corticosterone production in dermal fibroblasts
    • Slominski A, Zbytek B, Semak I, et al. (2005a) CRH stimulates POMC activity and corticosterone production in dermal fibroblasts. J Neuroimmunol 162: 97-102
    • (2005) J Neuroimmunol , vol.162 , pp. 97-102
    • Slominski, A.1    Zbytek, B.2    Semak, I.3
  • 37
    • 15444364708 scopus 로고    scopus 로고
    • CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH
    • Slominski A, Zbytek B, Szczesniewski A, et al. (2005b) CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH. Am J Physiol Endocrinol Metab 288:E701-6
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E701-e706
    • Slominski, A.1    Zbytek, B.2    Szczesniewski, A.3
  • 38
    • 33646141864 scopus 로고    scopus 로고
    • Cultured human dermal fibroblasts do produce cortisol
    • Slominski A, Zbytek B, Szczesniewski A, et al. (2006) Cultured human dermal fibroblasts do produce cortisol. J Invest Dermatol 126:1177-8
    • (2006) J Invest Dermatol , vol.126 , pp. 1177-1178
    • Slominski, A.1    Zbytek, B.2    Szczesniewski, A.3
  • 39
    • 8644251210 scopus 로고    scopus 로고
    • A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin
    • Slominski A, Zjawiony J, Wortsman J, et al. (2004) A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin. Eur J Biochem 271:4178-88
    • (2004) Eur J Biochem , vol.271 , pp. 4178-4188
    • Slominski, A.1    Zjawiony, J.2    Wortsman, J.3
  • 40
    • 84901490008 scopus 로고    scopus 로고
    • Cutaneous glucocorticosteroidogenesis: Securing local homeostasis and the skin integrity
    • Slominski AT, Manna PR, Tuckey RC. (2014) Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity. Exp Dermatol 23:369-74
    • (2014) Exp Dermatol , vol.23 , pp. 369-374
    • Slominski, A.T.1    Manna, P.R.2    Tuckey, R.C.3
  • 41
    • 84887829127 scopus 로고    scopus 로고
    • Key role of CRF in the skin stress response system
    • Slominski AT, Zmijewski MA, Zbytek B, et al. (2013b) Key role of CRF in the skin stress response system. Endocr Rev 34:827-84
    • (2013) Endocr Rev , vol.34 , pp. 827-884
    • Slominski, A.T.1    Zmijewski, M.A.2    Zbytek, B.3
  • 42
    • 77957258311 scopus 로고    scopus 로고
    • Role of epithelial sodium channels and their regulators in hypertension
    • Soundararajan R, Pearce D, Hughey RP, et al. (2010) Role of epithelial sodium channels and their regulators in hypertension. J Biol Chem 285:30363-9
    • (2010) J Biol Chem , vol.285 , pp. 30363-30369
    • Soundararajan, R.1    Pearce, D.2    Hughey, R.P.3
  • 43
    • 34250742595 scopus 로고    scopus 로고
    • Spironolactone modulates expressions of cardiac mineralocorticoid receptor and 11betahydroxysteroid dehydrogenase 2 and prevents ventricular remodeling in post-infarct rat hearts
    • Takeda M, Tatsumi T, Matsunaga S, et al. (2007) Spironolactone modulates expressions of cardiac mineralocorticoid receptor and 11betahydroxysteroid dehydrogenase 2 and prevents ventricular remodeling in post-infarct rat hearts. Hypertens Res 30:427-37
    • (2007) Hypertens Res , vol.30 , pp. 427-437
    • Takeda, M.1    Tatsumi, T.2    Matsunaga, S.3
  • 44
    • 0022577787 scopus 로고
    • Lack of effect of topical spironolactone on sebum excretion
    • Walton S, Cunliffe WJ, Lookingbill P, et al. (1986) Lack of effect of topical spironolactone on sebum excretion. Br J Dermatol 114:261-4
    • (1986) Br J Dermatol , vol.114 , pp. 261-264
    • Walton, S.1    Cunliffe, W.J.2    Lookingbill, P.3
  • 45
    • 72149099639 scopus 로고    scopus 로고
    • Mineralocorticoid receptors in the metabolic syndrome
    • Zennaro MC, Caprio M, Feve B (2009) Mineralocorticoid receptors in the metabolic syndrome. Trends Endocrinol Metab 20:444-51
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 444-451
    • Zennaro, M.C.1    Caprio, M.2    Feve, B.3
  • 46
    • 84863548606 scopus 로고    scopus 로고
    • Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy
    • Zhao M, Celerier I, Bousquet E, et al. (2012) Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy. J Clin Invest 122: 2672-9
    • (2012) J Clin Invest , vol.122 , pp. 2672-2679
    • Zhao, M.1    Celerier, I.2    Bousquet, E.3
  • 47
    • 40049084368 scopus 로고    scopus 로고
    • Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-Thickness skin model
    • Zoller NN, Kippenberger S, Thaci D, et al. (2008) Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-Thickness skin model. Toxicol In Vitro 22:747-59
    • (2008) Toxicol in Vitro , vol.22 , pp. 747-759
    • Zoller, N.N.1    Kippenberger, S.2    Thaci, D.3


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