The role of sarcopenia with and without fracture

Injury

Volumn 47, Issue , 2016, Pages S3-S10

  Tarantino, Umberto ^a   Baldi, Jacopo ^a   Scimeca, Manuel ^b,c   Piccirilli, Eleonora ^a   Piccioli, Andrea ^d   Bonanno, Elena ^b   Gasbarra, Elena ^a  

^a TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c ITALIAN SPACE AGENCY   (Italy)

^d POLICLINICO UMBERTO I   (Italy)

Author keywords

Aging; BMP2; Hip fracture; Muscle fibre atrophy; Myostatin; Osteoarthritis; Osteoporosis; Risk of falling; Sarcopenia; Satellite cells

Indexed keywords

AGED; AGING; ARTICLE; BODY MASS; BONE ATROPHY; BONE DENSITY; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FRACTURE; FUNCTIONAL DISEASE; HIP FRACTURE; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MUSCLE BIOPSY; MUSCLE FUNCTION; OSTEOARTHRITIS; OSTEOPOROSIS; PHYSICAL ACTIVITY; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; SARCOPENIA; TOTAL HIP PROSTHESIS; TRANSMISSION ELECTRON MICROSCOPY; VASTUS LATERALIS MUSCLE; COMPLICATION; FRAGILITY FRACTURE; HIP REPLACEMENT; ITALY; PATHOPHYSIOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AGING; ARTHROPLASTY, REPLACEMENT, HIP; BONE DENSITY; FEMALE; HIP FRACTURES; HUMANS; IMMUNOHISTOCHEMISTRY; ITALY; OSTEOARTHRITIS; OSTEOPOROSIS; OSTEOPOROTIC FRACTURES; SARCOPENIA;

EID: 84997173180     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2016.07.057     Document Type: Article

References (46)

1. [1] Rosenberg, I.H., Summary comments: epidemiological and methodological problems in determining nutritional status of older persons. Am J Clin Nutr 50 (1989), 1231–1233.
2. [2] Rosenberg, I.H., Sarcopenia: origins and clinical relevance. J Nutr 127:Suppl. 5 (1997), 990S–991S.
3. [3] Morley, J.E., Baumgartner, R.N., Roubenoff, R., Mayer, J., Nair, K.S., Sarcopenia. J Lab Clin Med 137:4 (2001), 231–243.
4. [4] Lang, T., Streeper, T., Cawthon, P., Baldwin, K., Taaffe, D.R., Harris, T.B., Sarcopenia: etiology, clinical consequences, intervention, and assessment. Osteoporos Int 21:4 (2010), 543–559.
5. [5] Marzetti, E., Calvani, R., Cesari, M., Buford, T.W., Lorenzi, M., Behnke, B.J., Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials. Int J Biochem Cell Biol 45 (2013), 2288–2301.
6. [6] Vasilaki, A., Jackson, M.J., Role of reactive oxygen species in the defective regeneration seen in aging muscle. Free Radic Biol Med 65 (2013), 317–323.
7. [7] Burks, T.N., Cohn, R.D., Role of TGF-β signaling in inherited and acquired myopathies. Skeletal Muscle, 1, 2011, 19.
8. [8] Hamrick, M.W., A role for myokines in muscle-bone interactions. Exerc Sport Sci Rev 39 (2011), 43–47.
9. [9] Hamrick, M.W., The skeletal muscle secretome: an emerging player in muscle-bone crosstalk. Bone Key Rep, 1, 2012, 60.
10. [10] Piccirilli, E., Gasbarra, E., Baldi, J., Pistillo, P., Tarantino, U., Can muscular impairment be the key for femoral fracture?. J Gerontol Geriatr Res, 3, 2014, 183.
11. [11] Cerocchi, I., Ghera, S., Gasbarra, E., Scialdoni, A., Tarantino, U., Fragility fractures: the clinical pathway. Aging Clin Exp Res 25 (2013), S43–5.
12. [12] Celi, M., Rao, C., Scialdoni, A., Tempesta, V., Gasbarra, E., Pistillo, P., Bone mineral density evaluation in osteoporosis: why yes and why not?. Aging Clin Exp Res 25 (2013), S47–9.
13. [13] Fox, C.H., Johnson, F.B., Whiting, J., Roller, P.P., Formaldehyde fixation. J Histochem Cytochem 33 (1985), 845–853.
14. [14] Brooke, M.H., Engel, W.K., The histographic analysis of human muscle biopsies with regard to fiber types: 2: Diseases of the upper and lower motor neuron. Neurology 19 (1969), 378–393.
15. [15] Dubowitz, V., Sewry, C.A., Muscle biopsy: a practical approach. 2007, Elsevier, New York.
16. [16] Scimeca, M., Giannini, E., Antonacci, C., Pistolese, C.A., Spagnoli, L.G., Bonanno, E., Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics. BMC Cancer, 14, 2014, 286.
17. [17] Scimeca, M., Orlandi, A., Terrenato, I., Bischetti, S., Bonanno, E., Assessment of metal contaminants in non-small cell lung cancer by EDX microanalysis. Eur J Histochem, 58, 2014, 2403.
18. [18] Reynolds, E.S., The use of lead citrate at high pH as an electron opaque stain based on metal chelation. J Cell Biol 17 (1963), 208–212.
19. [19] Heidari, B., Hosseini, R., Javadian, Y., Bijani, A., Sateri, M.H., Nouroddini, H.G., Factors affecting bone mineral density in postmenopausal women. Arch Osteoporos, 10, 2015, 217.
20. [20] Lloyd, J.T., Alley, D.E., Hawkes, W.G., Hochberg, M.C., Waldstein, S.R., Orwig, D.L., Body mass index is positively associated with bone mineral density in US older adults. Arch Osteoporos, 9, 2014, 175.
21. [21] Tarantino, U., Baldi, J., Celi, M., Rao, C., Liuni, F.M., Iundusi, R., Osteoporosis and sarcopenia: the connections. Aging Clin Exp Res 25 (2013), S93–5.
22. [22] Biolo, G., Cederholm, T., Muscaritoli, M., Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia. Clin Nutr 33 (2014), 737–748.
23. [23] Sartori, R., Sandri, M., Bone and morphogenetic protein signalling and muscle mass. Curr Opin Clin Nutr Metab Care 18 (2015), 215–220.
24. [24] Sartori, R., Gregorevic, P., Sandri, M., TGFb and BMP signaling in skeletal muscle: potential significance for muscle-related disease. Trends Endocrinol Metab 25 (2014), 464–471.
25. [25] Huang, H.Y., Zhang, W.T., Jiang, W.Y., RhoGDIb inhibits bone morphogenetic protein 4 (BMP4)-induced adipocyte lineage commitment and favors smooth muscle-like cell differentiation. J Biol Chem 290 (2015), 11119–11129.
26. [26] Vandervoort, A.A., Aging of the human neuromuscular system. Muscle Nerve 25 (2002), 17–25.
27. [27] Cheng, A., Morsch, M., Murata, Y., Ghazanfari, N., Reddel, S.W., Phillips, W.D., Sequence of age-associated changes to the mouse neuromuscular junction and the protective effects of voluntary exercise. PLoS One, 8, 2013, e67970.
28. [28] Purves-Smith, F.M., Sgarioto, N., Hepple, R.T., Fiber typing in aging muscle. Exerc Sport Sci Rev 42 (2014), 45–52.
29. [29] Pedersen, B.K., Muscles and their myokines. J Exp Biol 214 (2011), 337–346.
30. [30] Hamrick, M.W., McNeil, P.L., Patterson, S.L., Role of muscle-derived growth factors in bone formation. J Musculoskelet Neuronal Interact 10 (2010), 64–70.
31. [31] Johnson, R.W., White, J.D., Walker, E.C., Martin, T.J., Sims, N.A., Myokines (muscle-derived cytokines and chemokines) including ciliary neurotrophic factor (CNTF) inhibit osteoblast differentiation. Bone 64 (2014), 47–56.
32. [32] Raschke, S., Eckardt, K., Bjorklund Holven, K., Jensen, J., Eckel, J., Identification and validation of novel contraction-regulated myokines released from primary human skeletal muscle cells. PLoS One, 8, 2013, e62008.
33. [33] Scheler, M., Irmler, M., Lehr, S., Hartwig, S., Staiger, H., Al-Hasani, H., Cytokine response of primary human myotubes in an in vitro exercise model. Am J Physiol Cell Physiol 305 (2013), C877–86.
34. [34] Adams, G.R., Haddad, F., Bodell, P.W., Tran, P.D., Baldwin, K.M., Combined isometric, concentric, and eccentric resistance exercise prevents unloading-induced muscle atrophy in rats. J Appl Physiol 103 (2007), 1644–1654.
35. [35] Rojas Vega, S., Knicker, A., Hollmann, W., Bloch, W., Struder, H.K., Effect of resistance exercise on serum levels of growth factors in humans. Horm Metab Res 42 (2010), 982–986.
36. [36] Fry, C.S., Drummond, M.J., Glynn, E.L., Dickinson, J.M., Gundermann, D.M., Timmerman, K.L., Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis. Skelet Muscle, 1, 2011, 11.
37. [37] Alsharidah, M., Lazarus, N.R., George, T.E., Agley, C.C., Velloso, C.P., Harridge, S.D., Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture. Aging Cell 12 (2013), 333–344.
38. [38] Rosen, C.J., Bouxsein, M.L., Mechanisms of disease: is osteoporosis the obesity of bone?. Nature Clin Practice Rheumatol 2 (2006), 35–43.
39. [39] Mayhew, P.M., Thomas, C.D., Clement, J.G., Loveridge, N., Beck, T.J., Bonfield, W., Relation between age, femoral neck cortical stability, and hip fracture risk. Lancet 366 (2005), 129–135.
40. [40] Poole, K.E., Mayhew, P.M., Rose, C.M., Brown, J.K., Bearcroft, P.J., Loveridge, N., Changing structure of the femoral neck across the adult female lifespan. J Bone Miner Res 25 (2010), 482–491.
41. [41] Johannesdottir, F., Aspelund, T., Reeve, J., Poole, K.E., Sigurdsson, S., Harris, T.B., Similarities and differences between sexes in regional loss of cortical and trabecular bone in the mid-femoral neck: the AGES-Reykjavik Longitudinal Study. J Bone Miner Res 28 (2013), 2165–2176.
42. [42] Mayhew, P.M., Ross, C.M., Brown, K., Bearcroft, P., Loveridge, N., Reeve, J., et al. Asymmetric femoral neck trabecular bone loss with ageing: relative preservation of the inferior region. J Bone Joint Surg Br, 93(Suppl. 1), 2011, 69.
43. [43] Thomas, C.D., Mayhew, P.M., Power, J., Poole, K.E., Loveridge, N., Clement, J.G., Femoral neck trabecular bone: loss with aging and role in preventing fracture. J Bone Miner Res 24 (2009), 1808–1818.
44. [44] Martelli, S., Kersh, M.E., Schache, A.G., Pandy, M.G., Strain energy in the femoral neck during exercise. J Biomech 47 (2014), 1784–1791.
45. [45] Jarvinen, T.L., Kannus, P., Sievanen, H., Have DXA-based exercise studies seriously underestimated the effects of mechanical loading on bone?. J Bone Miner Res 14 (1999), 1634–1635.
46. [46] Halvarsson, A., Franzén, E., Sta°hle, A., Balance training with multi-task exercises improves fall-related self-efficacy, gait, balance performance and physical function in older adults with osteoporosis: a randomized controlled trial. Clin Rehabil 29:4 (2015), 365–370.