A role for myokines in muscle-bone interactions

Exercise and Sport Sciences Reviews

Volumn 39, Issue 1, 2011, Pages 43-47

  Hamrick, Mark W ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

FGF 2; IGF 1; muscle injury; myostatin; periosteum

Indexed keywords

CYTOKINE; SIGNAL PEPTIDE;

ANIMAL; ARTICLE; BONE; HUMAN; MUSCLE; PARACRINE SIGNALING; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; BONE AND BONES; CYTOKINES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLES; PARACRINE COMMUNICATION; SIGNAL TRANSDUCTION;

EID: 78651383185     PISSN: 00916331     EISSN: None     Source Type: Journal    
DOI: 10.1097/JES.0b013e318201f601     Document Type: Article

References (35)

1. Bortoluzzi S, Scanapieco P, Castaro A, Danieli G, Schiaffino S. Computational reconstruction of the human skeletal muscle secretome. Proteins. 2006; 62:776-92.
2. Cairns DM, Lee P, Uchimura T, Seufert CR, Kwon H, Zeng L. The role of muscle cells in regulating cartilage matrix production. J. Orthop. Res. 2010; 28:529-36.
3. Chan X, McDermott J, Siu K. Identification of secreted proteins during skeletal muscle development. J. Proteome Res. 2007; 6:698-710.
4. Clarke M, Khakee R, McNeil PL. Loss of cytoplasmic basic fibroblast growth factor from physiologically wounded myofibers of normal and dystrophic muscle. J. Cell. Sci. 1993; 106:121-33.
5. D'Amore PA, Brown R, Ku P, et al. Elevated basic fibroblast growth factor in the serum of patients with Duchenne muscular dystrophy. Ann. Neurol. 1994; 35:362-5.
6. Elkasrawy M, Hamrick MW. Myostatin (GDF-8) as a key factor linking muscle mass and bone structure. J. Musculoskelet. Neuronal Interact. 2010; 10:56-63.
7. Giston H, Schakman O, Combaret L, et al. Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy. Endrocrinology. 2007; 148:452-60.
8. Gross T, Poliachik S, Prasad J, Bain SD. The effect of muscle dysfunction on bone mass and morphology. J. Musculoskelet. Neuronal Interact. 2010; 10:25-34.
9. Hamrick MW, Samaddar T, Pennington C, McCormick J. Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise. J. Bone Miner. Res. 2006; 21:477-83.
10. Hamrick MW, Shi X, Zhang W, et al. Loss of myostatin function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading. Bone. 2007; 40:1544-53.
11. Hamrick MW, Ferrari SL. Leptin and the sympathetic connection of fat to bone. Osteoporos. Intl. 2008; 19:905-12.
12. Hamrick MW, Della-Fera MA, Baile CA, Pollock NK, Lewis RD. Body fat as a regulator of bone mass: experimental evidence from animal models. Clin. Rev. Bone Miner. Metab. 2009; 7:224-9.
13. Hamrick MW, McNeil PL, Patterson SL. Role of muscle-derived growth factors in bone formation. J. Musculoskelet. Neuronal Interact. 2010; 10:64-70.
14. Harry L, Sandison A, Paleolog E, Hansen U, Pearse M, Nanchanal J. Comparison of the healing of open tibial fractures covered with either muscle or fasciocutaneous tissue in a murine model. J. Orthop. Res. 2008; 26:1238-44.
15. Haugk K, Roeder R, Garber M, Schelling G. Regulation of muscle cell proliferation by extracts from crushed muscle. J. Anim. Sci. 1995; 73:1972-81.
16. Hittel DS, Berggren J, Shearer J, Boyle K, Houmard J. Increased secretion and expression of myostatin in skeletal muscle from extremely obese women. Diabetes. 2009; 58:30-8.
17. Hittel DS, Axelson M, Sarna N, Shearer J, Huffman KM, Kraus WE. Myostatin decreases with aerobic exercise and associates with insulin resistance. Med. Sci. Sports Exerc. 2010; 42:2023-9.
18. Judex S, Rubin C. Is bone formation induced by high-frequency mechanical signals modulated by muscle activity? J. Musculoskelet. Neuronal Interact. 2010; 10:3-11.
19. Kaufman H, Reznick A, Stein H, Barak M, Maor G. The biological basis of the bone-muscle inter-relationship in the algorithm of fracture healing. Orthopedics. 2008; 31:751.
20. Kellum E, Starr H, Immel D, et al. Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume. Bone. 2009; 44:17-23.
21. Lang CH, Silvis C, Nystrom G, Frost AR. Regulation of myostatin by glucocorticoids after thermal injury. FASEB J. 2001; 15:1807-9.
22. Lee NK, Sowa H, Hinoi E, et al. Endocrine regulation of energy metabolism by the skeleton. Cell. 2007; 130:456-69.
23. Lee SJ. Regulation of muscle mass by myostatin. Ann. Rev. Cell Dev. Biol. 2004; 20:61-86.
24. Liang H, Pun S, Wronski TJ. Bone anabolic effects of basic fibro-blast growth factor in ovariectomized rats. Endocrinology. 1999; 140: 5780-8.
25. Lorentzon M, Landin K, Mellstrom D, Ohlsson C. Leptin is a negative independent predictor of areal BMD and cortical bone size in young adult Swedish men. J. Bone Miner. Res. 2006; 21:1871-8.
26. Ma K, Mallidis C, Bhasin S, et al. Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression. Am. J. Physiol. Endocrinol. Metab. 2003; 285:E363-71.
27. Miyake K, McNeil PL. Mechanical injury and repair of cells. Crit. Care Med. 2003: 31:S496-501.
28. Pedersen B. Muscle as an endocrine organ: IL-6 and other myokines. J. Appl. Physiol. 2009; 107:1006-14.
29. Pollock N, Laing E, Baile C, Hamrick MW, Hall DB, Lewis R. Is adiposity advantageous for bone strength? A peripheral and quantitative computed tomography study in late adolescent females. Am. J. Clin. Nutr. 2007; 86:1530-8.
30. Reid IR. Relationships between fat and bone. Osteoporos. Int. 2008; 19:595-606.
31. Stein H, Perren SM, Cordey J, Kenwright J, Mosheiff R, Francis MJ. The muscle bed V a crucial factor in fracture healing: a physiological concept. Orthopedics. 2002; 25:1379-83.
32. Turner JD, Rotwein P, Novakofski J, Bechtel P. Induction of mRNA for IGF-1 and IGF-II during growth-hormone stimulated muscle hypertrophy. Am. J. Physiol. 1988; 255:E513-7.
33. Vogt P, Boorboor P, Vaske B, Topsakal E, Schneider M, Muehlberger T. Significant angiogenic potential is present in the microenvironment of muscle flaps in humans. J. Reconstr. Microsurg. 2005; 21:517-23.
34. Walsh K. Adipokines, myokines, and cardiovascular disease. Circ. J. 2009; 73:13-8.
35. Yakar S, Rosen CJ, Beamer WG, et al. Circulating levels of IGF-1 directly regulate bone growth and density. J. Clin. Invest. 2002; 110:771-81.