Vps35-dependent recycling of Trem2 regulates microglial function

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Volumn 17, Issue 12, 2016, Pages 1286-1296

  Yin, Jie ^a,b   Liu, Xiaocui ^c   He, Qing ^a,b   Zhou, Lujun ^a,b   Yuan, Zengqiang ^a,d   Zhao, Siqi ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SHANDONG MENTAL HEALTH CENTER   (China)

^d BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

Author keywords

Alzheimer's disease; microglia; receptor recycling; retromer; Trem2; Vps35

Indexed keywords

CELL MEMBRANE PROTEIN; CLATHRIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG; VACUOLAR PROTEIN SORTING 35; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN-6, MOUSE; MEMBRANE PROTEIN; NOS2 PROTEIN, MOUSE; TREM2 PROTEIN, MOUSE; VESICULAR TRANSPORT PROTEIN; VPS35 PROTEIN, MOUSE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOCYTOSIS; INFLAMMATION; INTERNALIZATION; INTRACELLULAR TRANSPORT; LYSOSOME; MICROGLIA; MOUSE; MUTATION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; WILD TYPE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL MEMBRANE; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ALZHEIMER DISEASE; ANIMALS; CELL MEMBRANE; ENDOCYTOSIS; HEK293 CELLS; HELA CELLS; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LYSOSOMES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICROGLIA; MUTATION; NITRIC OXIDE SYNTHASE TYPE II; PHAGOCYTOSIS; PROTEIN TRANSPORT; RECEPTORS, IMMUNOLOGIC; VESICULAR TRANSPORT PROTEINS;

EID: 84996956254     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12451     Document Type: Article

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