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Volumn 2, Issue 8, 2015, Pages 810-820

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease

(18)  Tosto, Giuseppe a,b   Fu, Hongjun a   Vardarajan, Badri N a,b   Lee, Joseph H a,b   Cheng, Rong a,b   Reyes Dumeyer, Dolly a,b   Lantigua, Rafael c   Medrano, Martin d   Jimenez Velazquez, Ivonne Z e   Elkind, Mitchell S V b,f   Wright, Clinton B g   Sacco, Ralph L g   Pericak Vance, Margaret g   Farrer, Lindsay h   Rogaeva, Ekaterina i   St George Hyslop, Peter i,j   Reitz, Christiane a,b,f   Mayeux, Richard a,b,f  


Author keywords

[No Author keywords available]

Indexed keywords

F BOX PROTEIN; LEUCINE RICH REPEAT KINASE 7; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 84996777256     PISSN: None     EISSN: 23289503     Source Type: Journal    
DOI: 10.1002/acn3.223     Document Type: Article
Times cited : (52)

References (44)
  • 1
    • 84875354777 scopus 로고    scopus 로고
    • 2013 Alzheimer's disease facts and figures
    • Thies W, Bleiler L. 2013 Alzheimer's disease facts and figures. Alzheimers Dement 2013;9:208-245.
    • (2013) Alzheimers Dement , vol.9 , pp. 208-245
    • Thies, W.1    Bleiler, L.2
  • 2
    • 0031839545 scopus 로고    scopus 로고
    • Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study
    • Slooter AJ, Cruts M, Kalmijn S, et al. Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study. Arch Neurol 1998;55:964-968.
    • (1998) Arch Neurol , vol.55 , pp. 964-968
    • Slooter, A.J.1    Cruts, M.2    Kalmijn, S.3
  • 3
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study indentifies variants at CLU and CR1 associated with Alzheimer's disease
    • Lambert J-C, Heath S, Even G, et al. Genome-wide association study indentifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 2009;41:1094-1099.
    • (2009) Nat Genet , vol.41 , pp. 1094-1099
    • Lambert, J.-C.1    Heath, S.2    Even, G.3
  • 4
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • Harold D, Abraham R, Hollingworth P, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 2009;41:1088-1093.
    • (2009) Nat Genet , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3
  • 5
    • 84888317489 scopus 로고    scopus 로고
    • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
    • Lambert JC, Ibrahim-Verbaas CA, Harold D, et al. Meta-analysis of 74, 046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet 2013;45:1452-1458.
    • (2013) Nat Genet , vol.45 , pp. 1452-1458
    • Lambert, J.C.1    Ibrahim-Verbaas, C.A.2    Harold, D.3
  • 6
    • 84884813914 scopus 로고    scopus 로고
    • Genome-wide association studies in Alzheimer's disease: a review
    • Tosto G, Reitz C. Genome-wide association studies in Alzheimer's disease: a review. Curr Neurol Neurosci Rep 2013;13:1-7.
    • (2013) Curr Neurol Neurosci Rep , vol.13 , pp. 1-7
    • Tosto, G.1    Reitz, C.2
  • 7
    • 0035830436 scopus 로고    scopus 로고
    • Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan
    • Tang M-X, Cross P, Andrews H, et al. Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology 2001;56:49-56.
    • (2001) Neurology , vol.56 , pp. 49-56
    • Tang, M.-X.1    Cross, P.2    Andrews, H.3
  • 8
    • 84875922261 scopus 로고    scopus 로고
    • Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ε(lunate)4, and the risk of late-onsheimer disease in African Americans
    • Reitz C, Jun G, Naj A, et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ε(lunate)4, and the risk of late-onset Alzheimer disease in African Americans. JAMA 2013;309:1483-1492.
    • (2013) JAMA , vol.309 , pp. 1483-1492
    • Reitz, C.1    Jun, G.2    Naj, A.3
  • 9
    • 84938678855 scopus 로고    scopus 로고
    • Inbreeding among Caribbean Hispanics from the Dominican Republic and its effects on risk of Alzheimer disease
    • Vardarajan BN, Schaid DJ, Reitz C, et al. Inbreeding among Caribbean Hispanics from the Dominican Republic and its effects on risk of Alzheimer disease. Genet Med 2014;doi:10.1038/gim.2014.161.
    • (2014) Genet Med
    • Vardarajan, B.N.1    Schaid, D.J.2    Reitz, C.3
  • 10
    • 84896759904 scopus 로고    scopus 로고
    • Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onsheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA)
    • Vardarajan BN, Faber KM, Bird TD, et al. Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA). JAMA Neurol 2014;71:315-323.
    • (2014) JAMA Neurol , vol.71 , pp. 315-323
    • Vardarajan, B.N.1    Faber, K.M.2    Bird, T.D.3
  • 11
    • 0032507032 scopus 로고    scopus 로고
    • The APOE-e(open)4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics
    • Tang M-X, Stern Y, Marder K, et al. The APOE-e(open)4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics. JAMA 1998;279:751-755.
    • (1998) JAMA , vol.279 , pp. 751-755
    • Tang, M.-X.1    Stern, Y.2    Marder, K.3
  • 12
    • 79952592605 scopus 로고    scopus 로고
    • Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals
    • Lee JH, Cheng R, Barral S, et al. Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals. Arch Neurol 2011;68:320-328.
    • (2011) Arch Neurol , vol.68 , pp. 320-328
    • Lee, J.H.1    Cheng, R.2    Barral, S.3
  • 13
    • 4744346011 scopus 로고    scopus 로고
    • Homocysteine and the risk of ischemic stroke in a triethnic cohort the Northern Manhattan Study
    • Sacco RL, Anand K, Lee H-S, et al. Homocysteine and the risk of ischemic stroke in a triethnic cohort the Northern Manhattan Study. Stroke 2004;35:2263-2269.
    • (2004) Stroke , vol.35 , pp. 2263-2269
    • Sacco, R.L.1    Anand, K.2    Lee, H.-S.3
  • 14
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011;7:263-269.
    • (2011) Alzheimers Dement , vol.7 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3
  • 15
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini J, Howie B, Myers S, et al. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 2007;39:906-913.
    • (2007) Nat Genet , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3
  • 16
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • Consortium 1000 Genomes Project, others.
    • Consortium 1000 Genomes Project, others. An integrated map of genetic variation from 1, 092 human genomes. Nature 2012;491:56-65.
    • (2012) Nature , vol.491 , pp. 56-65
  • 17
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
    • Skol AD, Scott LJ, Abecasis GR, Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 2006;38:209-213.
    • (2006) Nat Genet , vol.38 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 18
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006;38:904-909.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3
  • 19
    • 33846006923 scopus 로고    scopus 로고
    • Population structure and eigenanalysis
    • Patterson N, Price AL, Reich D. Population structure and eigenanalysis. PLoS Genet 2006;2:e190.
    • (2006) PLoS Genet , vol.2 , pp. e190
    • Patterson, N.1    Price, A.L.2    Reich, D.3
  • 20
    • 80054804726 scopus 로고    scopus 로고
    • Investigating population stratification and admixture using eigenanalysis of dense genotypes
    • Shriner D. Investigating population stratification and admixture using eigenanalysis of dense genotypes. Heredity 2011;107:413-420.
    • (2011) Heredity , vol.107 , pp. 413-420
    • Shriner, D.1
  • 21
    • 40749128980 scopus 로고    scopus 로고
    • A unified association analysis approach for family and unrelated samples correcting for stratification
    • Zhu X, Li S, Cooper RS, Elston RC. A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet 2008;82:352-365.
    • (2008) Am J Hum Genet , vol.82 , pp. 352-365
    • Zhu, X.1    Li, S.2    Cooper, R.S.3    Elston, R.C.4
  • 22
    • 78149265272 scopus 로고    scopus 로고
    • Robust relationship inference in genome-wide association studies
    • Manichaikul A, Mychaleckyj JC, Rich SS, et al. Robust relationship inference in genome-wide association studies. Bioinformatics 2010;26:2867-2873.
    • (2010) Bioinformatics , vol.26 , pp. 2867-2873
    • Manichaikul, A.1    Mychaleckyj, J.C.2    Rich, S.S.3
  • 23
    • 79952467494 scopus 로고    scopus 로고
    • GATES: a rapid and powerful gene-based association test using extended Simes procedure
    • Li M-X, Gui H-S, Kwan JS, Sham PC. GATES: a rapid and powerful gene-based association test using extended Simes procedure. Am J Hum Genet 2011;88:283-293.
    • (2011) Am J Hum Genet , vol.88 , pp. 283-293
    • Li, M.-X.1    Gui, H.-S.2    Kwan, J.S.3    Sham, P.C.4
  • 24
    • 69749099417 scopus 로고    scopus 로고
    • Fast model-based estimation of ancestry in unrelated individuals
    • Alexander DH, Novembre J, Lange K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res 2009;19:1655-1664.
    • (2009) Genome Res , vol.19 , pp. 1655-1664
    • Alexander, D.H.1    Novembre, J.2    Lange, K.3
  • 25
    • 79955464911 scopus 로고    scopus 로고
    • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onsheimer's disease
    • Naj AC, Jun G, Beecham GW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 2011;43:436-441.
    • (2011) Nat Genet , vol.43 , pp. 436-441
    • Naj, A.C.1    Jun, G.2    Beecham, G.W.3
  • 26
    • 77952816887 scopus 로고    scopus 로고
    • varLD: a program for quantifying variation in linkage disequilibrium patterns between populations
    • Ong RT-H, Teo Y-Y. varLD: a program for quantifying variation in linkage disequilibrium patterns between populations. Bioinformatics 2010;26:1269-1270.
    • (2010) Bioinformatics , vol.26 , pp. 1269-1270
    • Ong, R.-H.1    Teo, Y.-Y.2
  • 27
    • 0034213718 scopus 로고    scopus 로고
    • High-level neuronal expression of Abeta1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation
    • Mucke L, Masliah E, Yu G-Q, et al. High-level neuronal expression of Abeta1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci 2000;20:4050-4058.
    • (2000) J Neurosci , vol.20 , pp. 4050-4058
    • Mucke, L.1    Masliah, E.2    Yu, G.-Q.3
  • 28
    • 22344438508 scopus 로고    scopus 로고
    • Tau suppression in a neurodegenerative mouse model improves memory function
    • Santacruz K, Lewis J, Spires T, et al. Tau suppression in a neurodegenerative mouse model improves memory function. Science 2005;309:476-481.
    • (2005) Science , vol.309 , pp. 476-481
    • Santacruz, K.1    Lewis, J.2    Spires, T.3
  • 29
    • 0029807527 scopus 로고    scopus 로고
    • Control of memory formation through regulated expression of a CaMKII transgene
    • Mayford M, Bach ME, Huang Y-Y, et al. Control of memory formation through regulated expression of a CaMKII transgene. Science 1996;274:1678-1683.
    • (1996) Science , vol.274 , pp. 1678-1683
    • Mayford, M.1    Bach, M.E.2    Huang, Y.-Y.3
  • 30
    • 36549053104 scopus 로고    scopus 로고
    • A survey of genetic human cortical gene expression
    • Myers AJ, Gibbs JR, Webster JA, et al. A survey of genetic human cortical gene expression. Nat Genet 2007;39:1494-1499.
    • (2007) Nat Genet , vol.39 , pp. 1494-1499
    • Myers, A.J.1    Gibbs, J.R.2    Webster, J.A.3
  • 31
    • 41949086089 scopus 로고    scopus 로고
    • Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons
    • Liang WS, Reiman EM, Valla J, et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci USA 2008;105:4441-4446.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4441-4446
    • Liang, W.S.1    Reiman, E.M.2    Valla, J.3
  • 32
    • 84884211803 scopus 로고    scopus 로고
    • Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease
    • Lambert J-C, Grenier-Boley B, Harold D, et al. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Mol Psychiatry 2012;18:461-470.
    • (2012) Mol Psychiatry , vol.18 , pp. 461-470
    • Lambert, J.-C.1    Grenier-Boley, B.2    Harold, D.3
  • 33
    • 84908052274 scopus 로고    scopus 로고
    • The ubiquitin ligase FbxL7 regulates the Dachsous-Fat-Dachs system in Drosophila
    • Rodrigues-Campos M, Thompson BJ. The ubiquitin ligase FbxL7 regulates the Dachsous-Fat-Dachs system in Drosophila. Development 2014;141:4098-4103.
    • (2014) Development , vol.141 , pp. 4098-4103
    • Rodrigues-Campos, M.1    Thompson, B.J.2
  • 34
    • 84923171541 scopus 로고    scopus 로고
    • F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7
    • Liu Y, Lear T, Zhao Y, et al. F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7. Cell Death Dis 2015;6:e1630.
    • (2015) Cell Death Dis , vol.6 , pp. e1630
    • Liu, Y.1    Lear, T.2    Zhao, Y.3
  • 35
    • 84922430062 scopus 로고    scopus 로고
    • The Drosophila F-box protein Fbxl7 binds to the protocadherin Fat and regulates Dachs localization and Hippo signaling
    • Bosch JA, Sumabat TM, Hafezi Y, et al. The Drosophila F-box protein Fbxl7 binds to the protocadherin Fat and regulates Dachs localization and Hippo signaling. Elife 2014;3:e03383.
    • (2014) Elife , vol.3
    • Bosch, J.A.1    Sumabat, T.M.2    Hafezi, Y.3
  • 36
    • 79958171759 scopus 로고    scopus 로고
    • Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk
    • Kim M-Y, Mo J-S, Ann E-J, et al. Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk. J Cell Sci 2011;124:1831-1843.
    • (2011) J Cell Sci , vol.124 , pp. 1831-1843
    • Kim, M.-Y.1    Mo, J.-S.2    Ann, E.-J.3
  • 37
    • 84866394478 scopus 로고    scopus 로고
    • Neuronal expression of F-box and leucine-rich-repeat protein 2 decreases over Braak stages in the brains of Alzheimer's disease patients
    • Watanabe T, von der Kammer H, Wang X, et al. Neuronal expression of F-box and leucine-rich-repeat protein 2 decreases over Braak stages in the brains of Alzheimer's disease patients. Neurodegener Dis 2012;11:1-12.
    • (2012) Neurodegener Dis , vol.11 , pp. 1-12
    • Watanabe, T.1    von der Kammer, H.2    Wang, X.3
  • 38
    • 59649088353 scopus 로고    scopus 로고
    • FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome
    • Di Fonzo A, Dekker M, Montagna P, et al. FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome. Neurology 2009;72:240-245.
    • (2009) Neurology , vol.72 , pp. 240-245
    • Di Fonzo, A.1    Dekker, M.2    Montagna, P.3
  • 39
    • 84927618580 scopus 로고    scopus 로고
    • APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation
    • Shu R, Wong W, Ma Q, et al. APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation. Cell Death Dis 2015;6:e1651.
    • (2015) Cell Death Dis , vol.6 , pp. e1651
    • Shu, R.1    Wong, W.2    Ma, Q.3
  • 40
    • 84876807719 scopus 로고    scopus 로고
    • A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation
    • Zhang Y, Kent JW, Olivier M, et al. A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation. BMC Med Genomics 2013;6:14.
    • (2013) BMC Med Genomics , vol.6 , pp. 14
    • Zhang, Y.1    Kent, J.W.2    Olivier, M.3
  • 41
    • 77954646488 scopus 로고    scopus 로고
    • Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD)
    • Shi H, Medway C, Bullock J, et al. Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD). Int J Mol Epidemiol Genet 2010;1:53.
    • (2010) Int J Mol Epidemiol Genet , vol.1 , pp. 53
    • Shi, H.1    Medway, C.2    Bullock, J.3
  • 42
    • 77950343693 scopus 로고    scopus 로고
    • Transgenic mouse models of Alzheimer's disease: behavioral testing and considerations
    • Bryan KJ, Lee H, Perry G, et al. Transgenic mouse models of Alzheimer's disease: behavioral testing and considerations. 2009.
    • (2009)
    • Bryan, K.J.1    Lee, H.2    Perry, G.3
  • 43
    • 77951133654 scopus 로고    scopus 로고
    • Genome-wide association studies in diverse populations
    • Rosenberg NA, Huang L, Jewett EM, et al. Genome-wide association studies in diverse populations. Nat Rev Genet 2010;11:356-366.
    • (2010) Nat Rev Genet , vol.11 , pp. 356-366
    • Rosenberg, N.A.1    Huang, L.2    Jewett, E.M.3


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