Safflower (Catharmus tinctorius L.) oil supplementation in overnourished rats during early neonatal development: Effects on heart and liver function in the adult

Applied Physiology, Nutrition and Metabolism

Volumn 41, Issue 12, 2016, Pages 1271-1277

  Costa, Laís Ribeiro ^a   Macêdo, Patrícia Cavalcanti ^a   de Melo, Janatar Stella Vasconcelos ^a   Freitas, Cristiane Moura ^a   Alves, Aiany Simoes ^a   Barbosa, Humberto de Moura ^b   Lira, Eduardo ^b   Fernandes, Mariana Pinheiro ^a   Batista de Oliveira Hornsby, Manuella ^a   Lagranha, Claudia J ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b DEPARTAMENTO DE MICOLOGIA   (Brazil)

Author keywords

Carthamus tinctorius L. oil; Heart; Liver; Overnourishment; Oxidative status

Indexed keywords

OMEGA 6 FATTY ACID; PLANT MEDICINAL PRODUCT; SAFFLOWER OIL;

ADVERSE EFFECTS; ANIMAL; BLOOD; CARDIAC MUSCLE; CHEMISTRY; COMPARATIVE STUDY; DIET THERAPY; DIETARY SUPPLEMENT; FEMALE; HYPERGLYCEMIA; HYPERLIPIDEMIAS; LACTATION; LIVER; MALE; MATERNAL NUTRITION; METABOLISM; OBESITY; OVERNUTRITION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREGNANCY; RANDOMIZATION; SAFFLOWER; WEANING; WEIGHT GAIN; WISTAR RAT;

ANIMALS; CARTHAMUS TINCTORIUS; DIETARY SUPPLEMENTS; FATTY ACIDS, OMEGA-6; FEMALE; HYPERGLYCEMIA; HYPERLIPIDEMIAS; LACTATION; LIVER; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MYOCARDIUM; OBESITY; OVERNUTRITION; OXIDATIVE STRESS; PLANT PREPARATIONS; PREGNANCY; RANDOM ALLOCATION; RATS, WISTAR; SAFFLOWER OIL; WEANING; WEIGHT GAIN;

EID: 84996538516     PISSN: 17155312     EISSN: 17155320     Source Type: Journal    
DOI: 10.1139/apnm-2016-0191     Document Type: Article

References (49)

1. Aebi, H. 1984. Catalase in vitro. Methods Enzymol. 105: 121-126. doi:10.1016/S0076-6879(84)05016-3. PMID:6727660.
2. Aksenov, M.Y., and Markesbery, W.R. 2001. Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer’s disease. Neurosci. Lett. 302: 141-145. doi:10.1016/S0304-3940(01) 01636-6. PMID:11290407.
3. Bao, L.D., Wang, Y., Ren, X.H., Ma, R.L., Lv, H.J., and Agula, B. 2015. Hypolipidemic effect of safflower yellow and primary mechanism analysis. Genet. Mol. Res. 14: 6270-6278. doi:10.4238/2015.June.9.14. PMID:26125829.
4. Bei, F., Jia, J., Jia, Y.Q., Sun, J.H., Liang, F., Yu, Z.Y., and Cai, W. 2015. Long-term effect of early postnatal overnutrition on insulin resistance and serum fatty acid profiles in male rats. Lipids Health Dis. 14: 96. doi:10.1186/s12944-015-0094-2. PMID:26302954.
5. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254. doi:10.1016/0003-2697(76)90527-3. PMID:942051.
6. Brenna, J.T. 2011. Animal studies of the functional consequences of suboptimal polyunsaturated fatty acid status during pregnancy, lactation and early postnatal life. Matern. Child Nutr. 7(S2): 59-79. doi:10.1111/j.1740-8709.2011.00301.x. PMID:21366867.
7. Choi, Y.J., Sim, W.C., Choi, H.K., Lee, S.H., and Lee, B.H. 2013. alpha-Terpineol induces fatty liver in mice mediated by the AMP-activated kinase and sterol response element binding protein pathway. Food Chem. Toxicol. 55: 129-136. doi:10.1016/j.fct.2012.12.025. PMID:23274539.
8. Crescenzo, R., Bianco, F., Mazzoli, A., Giacco, A., Cancelliere, R., di Fabio, G., et al. 2015. Fat Quality Influences the Obesogenic Effect of High Fat Diets. Nutrients. 7: 9475-9491. doi:10.3390/nu7115480. PMID:26580650.
9. da Silva Pedroza, A.A., Lopes, A., Mendes da Silva, R.F., Braz, G.R., Nascimento, L.P., Ferreira, D.S., et al. 2015. Can fish oil supplementation and physical training improve oxidative metabolism in aged rat hearts? Life Sci. 137: 133-141. doi:10.1016/j.lfs.2015.07.021. PMID:26231695.
10. Dobiásová, M., and Frohlich, J. 2001. The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER(HDL)). Clin. Biochem. 34: 583-588. doi:10.1016/S0009-9120(01)00263-6. PMID:11738396.
11. Draper, H.H., Squires, E.J., Mahmoodi, H., Wu, J., Agarwal, S., and Hadley, M. 1993. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic. Biol. Med. 15: 353-363. doi:10.1016/0891-5849(93)90035-S. PMID:8225017.
12. Eisenberg, D.M., Davis, R.B., Ettner, S.L., Appel, S., Wilkey, S., Van Rompay, M., and Kessler, R.C. 1998. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 280: 1569-1575. PMID:9820257.
13. Ernst, E. 2002a. Herbal medicinal products during pregnancy: are they safe? BJOG 109: 227-235. PMID:11950176.
14. Ernst, E. 2002b. Herbal medicinal products during pregnancy? Phytomedicine, 9: 352-354. doi:10.1078/0944-7113-00149. PMID:12120817.
15. Fan, L., Zhao, H.Y., Xu, M., Zhou, L., Guo, H., Han, J., et al. 2009. Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector. J. Chromatogr. A. 1216: 2063-2070. PMID:18394634.
16. Gao, L.N., Cui, Y.L., Wang, Q.S., and Wang, S.X. 2013. Amelioration of Danhong injection on the lipopolysaccharide-stimulated systemic acute inflammatory reaction via multi-target strategy. J. Ethnopharmacol. 149: 772-782. doi:10. 1016/j.jep.2013.07.039. PMID:23954279.
17. Gao, L.N., Yan, K., Cui, Y.L., Fan, G.W., and Wang, Y.F. 2015. Protective effect of Slavia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharideinduced liver injury. World J. Gastroenterol. 21 (309079-9092). PMID:26290634.
18. Habig, W.H., Pabst, M.J., Fleischner, G., Gatmaitan, Z., Arias, I.M., and Jakoby, W.B. 1974. The identity of glutathione S-transferase B with ligandin, a major binding protein of liver. Proc. Natl. Acad. Sci. U. S. A. 71: 3879-3882. doi:10.1073/pnas.71.10.3879. PMID:4139704.
19. He, G.F. 1991. Resources of medicinal plants in China. Mem. Inst. Oswaldo Cruz, 86(S2): 9-12. doi:10.1590/S0074-02761991000600005. PMID:1842021.
20. Ji, C., Dai, Y., Jiang, W., Liu, J., Hou, M., Wang, J., et al. 2014. Postnatal overfeeding promotes early onset and exaggeration of high-fat diet-induced nonalcoholic fatty liver disease through disordered hepatic lipid metabolism in rats. J. Nutr. Biochem. 25: 1108-1116. doi:10.1016/j.jnutbio.2014.06.010. PMID:25154569.
21. Jurgonski, A., Juskiewicz, J., Zdunczyk, Z., and Król, B. 2012. Caffeoylquinic acid-rich extract from chicory seeds improves glycemia, atherogenic index, and antioxidant status in rats. Nutrition. 28: 300-306. doi:10.1016/j.nut.2011. 06.010. PMID:22014632.
22. Kazuma, K., Takahashi, T., Sato, K., Takeuchi, H., Matsumoto, T., and Okuno, T. 2000. Quinochalcones and flavonoids from fresh florets in different cultivars of Carthamus tinctorius L. Biosci. Biotechnol. Biochem. 64: 1588-1599. doi: 10.1271/bbb.64.1588. PMID:10993143.
23. Kim, M.N., Scao-Bogaert, F.L., and Paris, M. 1992. Flavonoids from Carthamus tinctorius Flowers. Planta Med. 58: 285-286. doi:10.1055/s-2006-961460. PMID:17226471.
24. Koyama, N., Suzuki, K., Furukawa, Y., Arisaka, H., Seki, T., Kuribayashi, K., et al. 2009. Effects of safflower seed extract supplementation on oxidation and cardiovascular risk markers in healthy human volunteers. Br. J. Nutr. 101: 568-575. PMID:18590590.
25. Lee, J.Y., Chang, E.J., Kim, H.J., Park, J.H., and Choi, S.W. 2002. Antioxidative flavonoids from leaves of Carthamus tinctorius. Arch. Pharm. Res. 25: 313-319. doi:10.1007/BF02976632. PMID:12135103.
26. Li, L., Yang, Y., Hou, X., Gu, D., Hang, B., Abdulla, R., et al. 2013. Bioassay-guided separation and purification of water-soluble antioxidants from Carthamus tinctorius L. by combination of chromatographic techniques. Sep. Purif. Technol. 104: 200-207. doi:10.1016/j.seppur.2012.11.027.
27. Liu, Z., Li, C., Li, M., Li, D., and Liu, K. 2004. The subchronic toxicity of hydroxysafflor yellow A of 90 days repeatedly intraperitoneal injections in rats. Toxicology. 203: 139-143. doi:10.1016/j.tox.2004.06.007. PMID:15363589.
28. Louei Monfared, A., and Salati, A.P. 2012. The effects of Carthamus tinctorius L. on placental histomorphology and survival of the neonates in mice. Avicenna J. Phytomed. 2: 146-152. PMID:25050244.
29. Misra, H.P., and Fridovich, I. 1972. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247: 3170-3175. PMID:4623845.
30. Nascimento, L., Freitas, C.M., Silva-Filho, R., Leite, A.C., Silva, A.B., da Silva, A.I., et al. 2014. The effect of maternal low-protein diet on the heart of adult offspring: role of mitochondria and oxidative stress. Appl. Physiol. Nutr. Metab. 39: 880-887. doi:10.1139/apnm-2013-0452. PMID:24905448.
31. Nie, P.H., Zhang, L., Zhang, W.H., Rong, W.F., and Zhi, J.M. 2012. The effects of hydroxysafflor yellow A on blood pressure and cardiac function. J. Ethnopharmacol. 139: 746-750. doi:10.1016/j.jep.2011.11.054. PMID:22197825.
32. NIH. 1985. Principles of Laboratory Animal Care, NIH publication 85-23. National Institutes of Health, Bethesda, MD. USA.
33. Nobakht, M., Fattahi, M., Hoormand, M., Milanian, I., Rahbar, N., and Mahmoudian, M. 2000. A study on the teratogenic and cytotoxic effects of safflower extract. J. Ethnopharmacol. 73: 453-459. doi:10.1016/S0378-8741(00) 00324-X. PMID:11090999.
34. Novelli, E.L., Diniz, Y.S., Galhardi, C.M., Ebaid, G.M., Rodrigues, H.G., Mani, F., et al. 2007. Anthropometrical parameters and markers of obesity in rats. Lab. Anim. 41: 111-119. doi:10.1258/002367707779399518. PMID:17234057.
35. Reznick, A.Z., and Packer, L. 1994. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol. 233: 357-363. PMID: 8015470.
36. Roh, J.S., Han, J.Y., Kim, J.H., and Hwang, J.K. 2004. Inhibitory effects of active compounds isolated from safflower (Carthamus tinctorius L.) seeds for melanogenesis. Biol. Pharm. Bull. 27: 1976-1978. doi:10.1248/bpb.27.1976. PMID: 15577216.
37. Sato, H., Kawagishi, H., Nishimura, T., Yoneyama, S., Yoshimoto, Y., Sakamura, S., et al. 1985. Serotobenine, a novel phenolic amide from safflower seeds (Carthamus tinctorius L.). Agric. Biol. Chem. 49: 2969-2974. doi: 10.1080/00021369.1985.10867182.
38. Smart, J.L., Adlard, B.P., and Dobbing, J. 1974. Further studies of body growth and brain development in "small-for-dates" rats. Biol. Neonate. 25: 135-150. doi: 10.1159/000240686. PMID:4451688.
39. Srivastava, J.K., Shankar, E., and Gupta, S. 2010. Chamomile: A herbal medicine of the past with bright future. Mol. Med. Rep. 3 (6895-901). PMID:21132119.
40. Tien, Y.C., Lin, J.Y., Lai, C.H., Kuo, C.H., Lin, W.Y., Tsai, C.H., et al. 2010. Carthamus tinctorius L. prevents LPS-induced TNFalpha signaling activation and cell apoptosis through JNK1/2-NFkappaB pathway inhibition in H9c2 cardiomyoblast cells. J. Ethnopharmacol. 130: 505-513. PMID:20538053.
41. Upadya, H., Devaraju, C.J., and Joshi, S.R. 2015. Anti-inflammatory properties of blended edible oil with synergistic antioxidants. Indian J. Endocrinol. Metab. 19: 511-519. doi:10.4103/2230-8210.159063. PMID:26180768.
42. Wang, C., Zhang, D., Li, G., Liu, J., Tian, J., Fu, F., and Liu, K. 2007. Neuroprotective effects of safflor yellow B on brain ischemic injury. Exp. Brain Res. 177: 533-539. doi:10.1007/s00221-006-0705-2. PMID:17006684.
43. Wang, C.Y., Liu, Q., Huang, Q.X., Liu, J.T., He, Y.H., Lu, J.J., and Bai, X.Y. 2013. Activation of PPARgamma is required for hydroxysafflor yellow A of Carthamus tinctorius to attenuate hepatic fibrosis induced by oxidative stress. Phytomedicine. 20: 592-599. doi:10.1016/j.phymed.2013.02.001. PMID:23523101.
44. Wang, Y., Chen, P., Tang, C., Wang, Y., Li, Y., and Zhang, H. 2014. Antinociceptive and anti-inflammatory activities of extract and two isolated flavonoids of Carthamus tinctorius L. J. Ethnopharmacol. 151: 944-950. doi:10.1016/j.jep.2013. 12.003. PMID:24333963.
45. Wei, X., Liu, H., Sun, X., Fu, F., Zhang, X., Wang, J., et al. 2005. Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action. Neurosci. Lett. 386: 58-62. doi:10.1016/j.neulet.2005.05.069. PMID:16002219.
46. Yang, M., Orgah, J., Zhu, J., Fan, G., Han, J., Wang, X., et al. 2016. Danhong injection attenuates cardiac injury induced by ischemic and reperfused neuronal cells through regulating arginine vasopressin expression and secretion. Brain Res. 1643: 516-523. PMID:27107944.
47. Zhang, Z., Li, Q., Liu, F., Sun, Y., and Zhang, J. 2010. Prevention of diet-induced obesity by safflower oil: insights at the levels of PPARalpha, orexin, and ghrelin gene expression of adipocytes in mice. Acta Biochim. Biophys. Sin. (Shanghai) 42: 202-208. PMID:20213045.
48. Zhao, G., Zheng, X.W., Gai, Y., Chu, W.J., Qin, G.W., and Guo, L.H. 2009. Safflower extracts functionally regulate monoamine transporters. J. Ethnopharmacol. 124: 116-124. doi:10.1016/j.jep.2009.04.002. PMID:19527825.
49. Zhu, H., Wang, Z., Ma, C., Tian, J., Fu, F., Li, C., et al. 2003. Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies. Planta Med. 69: 429-433. doi:10.1055/s-2003-39714. PMID:12802724.