The role of microRNAs in islet β-cell development

Cell Biology International

Volumn 40, Issue 12, 2016, Pages 1248-1255

  Kaviani, Maryam ^a   Azarpira, Negar ^a   Karimi, Mohammad Hossein ^a   Al Abdullah, Ismail ^b  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

diabetes mellitus; differentiation; gene expression; insulin producing cells; microRNAs

Indexed keywords

MICRORNA; MICRORNA 124A; MICRORNA 130B; MICRORNA 15; MICRORNA 16; MICRORNA 186; MICRORNA 195; MICRORNA 19B; MICRORNA 21; MICRORNA 342; MICRORNA 375; MICRORNA 382; MICRORNA 7; MICRORNA 9; UNCLASSIFIED DRUG;

CELL DIFFERENTIATION; CELL MATURATION; CELL REGENERATION; DIABETES MELLITUS; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; REVIEW; RNA ANALYSIS; UPREGULATION; ANIMAL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; HUMANS; INSULIN-SECRETING CELLS; MICRORNAS;

EID: 84996483260     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1002/cbin.10691     Document Type: Review

References (62)

1. Agulnick AD, Ambruzs DM, Moorman MA, Bhoumik A, Cesario RM, Payne JK, Kelly JR, Haakmeester C, Srijemac R, Wilson AZ (2015) Insulin-producing endocrine cells differentiated in vitro from human embryonic stem cells function in macroencapsulation devices in vivo. Stem Cells Transl Med 4: 1214–22.
2. Artner I, Blanchi B, Raum JC, Guo M, Kaneko T, Cordes S, Sieweke M, Stein R (2007) MafB is required for islet β cell maturation. Proc Natl Acad Sci USA 104(10): 3853–8.
3. Avnit-Sagi T, Kantorovich L, Kredo-Russo S, Hornstein E, Walker MD (2009) The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas. PLoS ONE 4(4): e5033.
4. Bai C, Li X, Gao Y, Wang K, Fan Y, Zhang S, Ma Y, Guan W (2016) Role of microRNA-21 in the formation of insulin-producing cells from pancreatic progenitor cells. Biochim Biophys Acta 1859(2): 280–93.
5. Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E (2007) MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic β-cell lines. J Biol Chem 282(27): 19575–88.
6. Bilotta F, Badenes R, Lolli S, Belda FJ, Einav S, Rosa G (2015) Insulin infusion therapy in critical care patients: regular insulin vs short-acting insulin. A prospective, crossover, randomized, multicenter blind study. J Crit Care 30(2): e431–6.
7. Bravo-Egana V, Rosero S, Molano RD, Pileggi A, Ricordi C, Domínguez-Bendala J, Pastori RL (2008) Quantitative differential expression analysis reveals miR-7 as major islet microRNA. Biochem Biophys Res Cummun 366(4): 922–6.
8. Cai J, Wu Z, Xu X, Liao L, Chen J, Huang L, Wu W, Luo F, Wu C, Pugliese A (2016) Umbilical cord mesenchymal stromal cell with autologous bone marrow cell transplantation in established type 1 diabetes: a pilot randomized controlled open-label clinical study to assess safety and impact on insulin secretion. Diabetes Care 39(1): 149–57.
9. Carrasco M, Rojas A, Delgado I, Vuilleumier NC, Tejedo JR, Bedoya FJ, Gauthier BR, Soria B, Martín F (2015) Regulation of pancreatic islet formation. In: Islam Md. S ed. Islets of Langerhans. Netherlands: Springer, pp. 109–28.
10. Carrington JC, Ambros V (2003) Role of microRNAs in plant and animal development. Science 301(5631): 336–8.
11. Chen J-F, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang D-Z (2006) The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38(2): 228–33.
12. Correa-Medina M, Bravo-Egana V, Rosero S, Ricordi C, Edlund H, Diez J, Pastori RL (2009) MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas. Gene Expr Patterns 9(4): 193–9.
13. Daoud J, Petropavlovskaia M, Rosenberg L, Tabrizian M (2010) The effect of extracellular matrix components on the preservation of human islet function in vitro. Biomaterials 31(7): 1676–82.
14. Dominguez-Bendala J, Klein D, Pastori R (2014) MicroRNAs in pancreas and islet development. Oxford: Academic Press.
15. Domínguez-Bendala J, Klein D, Pastori RL (2015) Chapter 16—MicroRNAs in pancreas and islet development A2—Sen. In: Chandan K ed. MicroRNA in regenerative medicine. Oxford: Academic Press, pp. 401–18.
16. Gabr MM, Zakaria MM, Refaie AF, Ismail AM, Abou-El-Mahasen MA, Ashamallah SA, Khater SM, El-Halawani SM, Ibrahim RY, Uin GS (2013) Insulin-producing cells from adult human bone marrow mesenchymal stem cells control streptozotocin-induced diabetes in nude mice. Cell Transplant 22(1): 133.
17. Gradwohl G, Dierich A, LeMeur M, Guillemot F (2000) Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci USA 97(4): 1607–11.
18. Gu G, Dubauskaite J, Melton DA (2002) Direct evidence for the pancreatic lineage: nGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129(10): 2447–57.
19. Hammar E, Parnaud G, Bosco D, Perriraz N, Maedler K, Donath M, Rouiller DG, Halban PA (2004) Extracellular matrix protects pancreatic β-cells against apoptosis role of short-and long-term signaling pathways. Diabetes 53(8): 2034–41.
20. Hanley N (2014) Closing in on pancreatic beta cells. Nat Biotechnol 32(11): 1100–2.
21. Jafarian A, Taghikani M, Abroun S, Allahverdi A, Lamei M, Lakpour N, Soleimani M (2015) The generation of insulin producing cells from human mesenchymal stem cells by MiR-375 and anti-MiR-9. PLoS ONE 10(6): e0128650.
22. Joglekar MV, Joglekar VM, Hardikar AA (2009) Expression of islet-specific microRNAs during human pancreatic development. Gene Expr Patterns 9(2): 109–13.
23. Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA (2007) MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol 311(2): 603–12.
24. Jung KH, McCarthy RL, Zhou C, Uprety N, Barton MC, Beretta L (2016) MicroRNA-194 regulates hepatocytic differentiation of progenitor cells by targeting YAP1. Stem Cells 34: 1284–96.
25. Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei F-Y, Hakim F, Kume S, Tomizawa K (2013) Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors. Stem Cells Transl Med 3: 114–27.
26. Kane NM, Howard L, Descamps B, Meloni M, McClure J, Lu R, McCahill A, Breen C, Mackenzie RM, Delles C (2012) Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells. Stem Cells 30(4): 643–54.
27. Keen H (1994) The diabetes control and complications trial (DCCT). Health Trends 26(2): 41–3.
28. Keller DM, McWeeney S, Arsenlis A, Drouin J, Wright CV, Wang H, Wollheim CB, White P, Kaestner KH, Goodman RH (2007) Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy. J Biol Chem 282(44): 32084–92.
29. Kelly WD, Lillehei RC, Merkel FK, Idezuki Y, Goetz FG (1967) Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery 61(6): 827–37.
30. Knudsen LA, Petersen N, Schwartz TW, Egerod KL (2015) The MicroRNA repertoire in enteroendocrine cells: identification of miR-375 as a potential regulator of the enteroendocrine lineage. Endocrinology 156(11): 3971–83.
31. Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E (2012a) Pancreas-enriched miRNA refines endocrine cell differentiation. Development 139(16): 3021–31.
32. Kredo-Russo S, Ness A, Mandelbaum AD, Walker MD, Hornstein E (2012b) Regulation of pancreatic microRNA-7 expression. Exp Diabetes Res 2012.
33. Kunisada Y, Tsubooka-Yamazoe N, Shoji M, Hosoya M (2012) Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells. Stem Cell Res 8(2): 274–84.
34. Lahmy R, Soleimani M, Sanati MH, Behmanesh M, Kouhkan F, Mobarra N (2013) Pancreatic islet differentiation of human embryonic stem cells by microRNA overexpression. J Tissue Eng Regen Med 10: 527–34.
35. Li T, Li H, Wang Y, Li T, Fan J, Xiao K, Zhao RC, Weng X (2016) MicroRNA-23a inhibits osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting LRP5. Int J Biochem Cell Biol 72: 55–62.
36. Lima MJ, Docherty HM, Chen Y, Docherty K (2012) Efficient differentiation of AR42J cells towards insulin-producing cells using pancreatic transcription factors in combination with growth factors. Mol Cell Endocrinol 358(1): 69–80.
37. Liu J, Liu Y, Wang H, Hao H, Han Q, Shen J, Shi J, Li C, Mu Y, Han W (2013) Direct differentiation of hepatic stem-like WB cells into insulin-producing cells using small molecules. Scientific Rep 3: 1–8.
38. Lyttle B, Li J, Krishnamurthy M, Fellows F, Wheeler M, Goodyer C, Wang R (2008) Transcription factor expression in the developing human fetal endocrine pancreas. Diabtologia 51(7): 1169–80.
39. McCall M, Shapiro J (2014) Islet cell transplantation. Semin Pediatr Surg 23(2): 83–90.
40. Moshrefi M, Yari N, Nabipour F, Bazrafshani MR, Nematollahi-mahani SN (2015) Transplantation of differentiated umbilical cord mesenchymal cells under kidney capsule for control of type I diabetes in rat. Tissue Cell 47: 395–405.
41. Murtaugh LC (2007) Pancreas and beta-cell development: from the actual to the possible. Development 134(3): 427–38.
42. Nekoei SM, Azarpira N, Sadeghi L, Kamalifar S (2015) In vitro differentiation of human umbilical cord Wharton's jelly mesenchymal stromal cells to insulin producing clusters. World J Clin Cases 3(7): 640.
43. Nieto M, Hevia P, Garcia E, Klein D, Alvarez-Cubela S, Bravo-Egana V, Rosero S, Damaris Molano R, Vargas N, Ricordi C (2012) Antisense miR-7 impairs insulin expression in developing pancreas and in cultured pancreatic buds. Cell Transplant 21(8): 1761–74.
44. Pellegrini S, Ungaro F, Mercalli A, Melzi R, Sebastiani G, Dotta F, Broccoli V, Piemonti L, Sordi V (2015) Human induced pluripotent stem cells differentiate into insulin-producing cells able to engraft in vivo. Acta Diabetol 52: 1–1.
45. Rezania A, Bruin JE, Arora P, Rubin A, Batushansky I, Asadi A, O'Dwyer S, Quiskamp N, Mojibian M, Albrecht T (2014) Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat Biotechnol 32(11): 1121–33.
46. Rosero S, Bravo-Egana V, Jiang Z, Khuri S, Tsinoremas N, Klein D, Sabates E, Correa-Medina M, Ricordi C, Domínguez-Bendala J (2010) MicroRNA signature of the human developing pancreas. BMC Genomics 11(1): 1.
47. Sambanis A (2014) Chapter 42—Bioartificial pancreas. In: Vacanti RLL ed. Principles of tissue engineering (Fourth Edition). Boston: Academic Press, pp. 849–68.
48. Sebastiani G, Po A, Miele E, Ventriglia G, Ceccarelli E, Bugliani M, Marselli L, Marchetti P, Gulino A, Ferretti E (2015) MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion. Acta Diabetol 52(3): 523–30.
49. Shaer A, Azarpira N, Karimi MH (2014a) Differentiation of human induced pluripotent stem cells into insulin-like cell clusters with miR-186 and miR-375 by using chemical transfection. Appl Biochem Biotechnol 174(1): 242–58.
50. Shaer A, Azarpira N, Vahdati A, Karimi M, Shariati M (2014b) miR-375 induces human decidua basalis-derived stromal cells to become insulin-producing cells. Cell Mol Biol Lett 19(3): 483–99.
51. Shaer A, Azarpira N, Vahdati A, Karimi MH, Shariati M (2015) Differentiation of human-induced pluripotent stem cells into insulin-producing clusters. Exp Clinical Transplant 13(1): 68–75.
52. Shi Y, Jin Y (2009) MicroRNA in cell differentiation and development. Sci China Series C: Life Sci 52(3): 205–11.
53. Soria B, Pezzolla D, López J, Rojas A, Hmadcha A (2014) Chapter 41—Generation of pancreatic islets from stem cells. In: Vacanti RLL ed. Principles of tissue engineering (Fourth Edition). Boston: Academic Press, pp. 837–47.
54. Stefani G, Slack FJ (2008) Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 9(3): 219–30.
55. Stoorvogel W (2012) Functional transfer of microRNA by exosomes. Blood 119(3): 646–8.
56. Timper K, Seboek D, Eberhardt M, Linscheid P, Christ-Crain M, Keller U, Müller B, Zulewski H (2006) Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem Biophys Res Cummun 341(4): 1135–40.
57. Van Pham P, Nguyen PT-M, Nguyen AT-Q, Pham VM, Bui AN-T, Dang LT-T, Nguyen KG, Phan NK (2014) Improved differentiation of umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells by PDX-1 mRNA transfection. Differentiation 87(5): 200–8.
58. Vanhoose AM, Samaras S, Artner I, Henderson E, Hang Y, Stein R (2008) MafA and MafB regulate Pdx1 transcription through the Area II control region in pancreatic β cells. J Biol Chem 283(33): 22612–9.
59. Wei R, Yang J, Liu G-Q, Gao M-J, Hou W-F, Zhang L, Gao H-W, Liu Y, Chen G-A, Hong T-P (2013) Dynamic expression of microRNAs during the differentiation of human embryonic stem cells into insulin-producing cells. Gene 518(2): 246–55.
60. Zhang C, Ye X, Zhang H, Ding M, Deng H (2007) GATA factors induce mouse embryonic stem cell differentiation toward extraembryonic endoderm. Stem Cells Dev 16(4): 605–14.
61. Zhang Z-W, Zhang L-Q, Ding L, Wang F, Sun Y-J, An Y, Zhao Y, Li Y-H, Teng C-B (2011) MicroRNA-19b downregulates insulin 1 through targeting transcription factor NeuroD1. FEBS Lett 585(16): 2592–8.
62. Zhang Y, Wang Z, Gemeinhart RA (2013) Progress in microRNA delivery. J Control Release 172(3): 962–74.