Efficient differentiation of AR42J cells towards insulin-producing cells using pancreatic transcription factors in combination with growth factors

Molecular and Cellular Endocrinology

Volumn 358, Issue 1, 2012, Pages 69-80

  Lima, Maria João ^a   Docherty, Hilary M ^a   Chen, Yuanxiao ^a,b   Docherty, Kevin ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Diabetes; Endocrine pancreas; Islets of langerhans; Pdx1; Stem cells

Indexed keywords

AMYLASE; BETACELLULIN; C PEPTIDE; GLUCAGON; GLUCOSE; GROWTH FACTOR; INSULIN; INSULIN 1; INSULIN 2; NEUROGENIN 3; NICOTINAMIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PAX4; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; EXOCRINE CELL; INSULIN RELEASE; INSULIN SENSITIVITY; NONHUMAN; NUCLEAR REPROGRAMMING; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINE; GLUCAGON; HOMEODOMAIN PROTEINS; INSULIN; INSULIN-SECRETING CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; NIACINAMIDE; PAIRED BOX TRANSCRIPTION FACTORS; PANCREAS; RATS; TRANS-ACTIVATORS;

EID: 84862782026     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.02.024     Document Type: Article

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