SCOPUS 정보 검색 플랫폼

Volumn 11, Issue 22, 2016, Pages 2501-2505

Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody–Drug Conjugation Chemistry

(7) Ekholm, Filip S a,b Pynnönen, Henna a Vilkman, Anja a Pitkänen, Virve a Helin, Jari a Saarinen, Juhani a Satomaa, Tero a

a GLYKOS FINLAND LTD (Finland)

b UNIVERSITY OF HELSINKI (Finland)

Author keywords

antibody drug conjugates; bioconjugation; carbohydrates; cytotoxic activity; structural characterization

Indexed keywords

ANTIBODY CONJUGATE; ANTIBODY DRUG CONJUGATE; BRENTUXIMAB VEDOTIN; CARBOHYDRATE DERIVATIVE; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; OLIGOPEPTIDE; VEDOTIN;

ARTICLE; CANCER CELL; CLINICAL TRIAL (TOPIC); CYTOTOXICITY; DERIVATIZATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; HUMAN; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SYNTHESIS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOCONJUGATES; MOLECULAR CONFORMATION; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84995773250 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201600372 Document Type: Article

Times cited : (17)

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