메뉴 건너뛰기




Volumn 180, Issue , 2017, Pages 103-117.e4

Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; BIOLOGICAL MARKER; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN BETA; CHEMOKINE RECEPTOR CCR5; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA 1; GELATINASE A; HYDROXYPROLINE; INTERLEUKIN 1BETA; MESSENGER RNA; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN C MYB; RANTES; REGULATORY FACTOR X1; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR ETS 2; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR PAX5; TRANSCRIPTION FACTOR PEA3; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR YY1; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR 1; X BOX BINDING PROTEIN 1; TRANSCRIPTION FACTOR;

EID: 84995770325     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2016.08.006     Document Type: Article
Times cited : (47)

References (63)
  • 1
    • 84897584484 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease in mainland of China: a meta-analysis of published studies
    • 1 Li, Z., Xue, J., Chen, P., Chen, L., Yan, S., Liu, L., Prevalence of nonalcoholic fatty liver disease in mainland of China: a meta-analysis of published studies. J Gastroenterol Hepatol 29 (2014), 42–51.
    • (2014) J Gastroenterol Hepatol , vol.29 , pp. 42-51
    • Li, Z.1    Xue, J.2    Chen, P.3    Chen, L.4    Yan, S.5    Liu, L.6
  • 2
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
    • 2 Browning, J.D., Szczepaniak, L.S., Dobbins, R., et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 40 (2004), 1387–1395.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 3
    • 33947121228 scopus 로고    scopus 로고
    • High prevalence of elevated liver enzymes in blood donors: associations with male gender and central adiposity
    • 3 Papatheodoridis, G.V., Goulis, J., Christodoulou, D., et al. High prevalence of elevated liver enzymes in blood donors: associations with male gender and central adiposity. Eur J Gastroenterol Hepatol 19 (2007), 281–287.
    • (2007) Eur J Gastroenterol Hepatol , vol.19 , pp. 281-287
    • Papatheodoridis, G.V.1    Goulis, J.2    Christodoulou, D.3
  • 4
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma
    • 4 Bugianesi, E., Leone, N., Vanni, E., et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 123 (2002), 134–140.
    • (2002) Gastroenterology , vol.123 , pp. 134-140
    • Bugianesi, E.1    Leone, N.2    Vanni, E.3
  • 5
    • 44649090001 scopus 로고    scopus 로고
    • Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease
    • 5 Barshop, N.J., Sirlin, C.B., Schwimmer, J.B., Lavine, J.E., Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease. Aliment Pharmacol Ther 28 (2008), 13–24.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 13-24
    • Barshop, N.J.1    Sirlin, C.B.2    Schwimmer, J.B.3    Lavine, J.E.4
  • 6
    • 84860326669 scopus 로고    scopus 로고
    • Nash is an inflammatory Disorder: Pathogenic, Prognostic and therapeutic implications
    • 6 Farrell, G.C., van Rooyen, D., Gan, L., Chitturi, S., Nash is an inflammatory Disorder: Pathogenic, Prognostic and therapeutic implications. Gut Liver 6 (2012), 149–171.
    • (2012) Gut Liver , vol.6 , pp. 149-171
    • Farrell, G.C.1    van Rooyen, D.2    Gan, L.3    Chitturi, S.4
  • 7
    • 47649108100 scopus 로고    scopus 로고
    • Body mass index is a stronger predictor of alanine aminotransaminase levels than alcohol consumption
    • 7 Adams, L.A., Knuiman, M.W., Divitini, M.L., Olynyk, J.K., Body mass index is a stronger predictor of alanine aminotransaminase levels than alcohol consumption. J Gastroenterol Hepatol 23 (2008), 1089–1093.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 1089-1093
    • Adams, L.A.1    Knuiman, M.W.2    Divitini, M.L.3    Olynyk, J.K.4
  • 10
    • 34548819916 scopus 로고    scopus 로고
    • Present and future therapeutic strategies in non-alcoholic fatty liver disease
    • 10 Calamita, G., Portincasa, P., Present and future therapeutic strategies in non-alcoholic fatty liver disease. Expert Opin Ther Targets 11 (2007), 1231–1249.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 1231-1249
    • Calamita, G.1    Portincasa, P.2
  • 11
    • 41849123475 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment
    • 11 Carter-Kent, C., Zein, N.N., Feldstein, A.E., Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment. Am J Gastroenterol 103 (2008), 1036–1042.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1036-1042
    • Carter-Kent, C.1    Zein, N.N.2    Feldstein, A.E.3
  • 12
    • 77951539837 scopus 로고    scopus 로고
    • The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)
    • 12 Liu, Q., Bengmark, S., Qu, S., The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD). Lipids Health Dis, 9, 2010, 42.
    • (2010) Lipids Health Dis , vol.9 , pp. 42
    • Liu, Q.1    Bengmark, S.2    Qu, S.3
  • 14
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two “hits”?
    • 14 Day, C.P., James, O.F., Steatohepatitis: a tale of two “hits”?. Gastroenterology 114 (1998), 842–845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 16
    • 0023687643 scopus 로고
    • A human T cell-specific molecule is a member of a new gene family
    • 16 Schall, T.J., Jongstra, J., Dyer, B.J., et al. A human T cell-specific molecule is a member of a new gene family. J Immunol 141 (1988), 1018–1025.
    • (1988) J Immunol , vol.141 , pp. 1018-1025
    • Schall, T.J.1    Jongstra, J.2    Dyer, B.J.3
  • 18
    • 68849118799 scopus 로고    scopus 로고
    • CCR1 and CCR5 promote hepatic fibrosis in mice
    • 18 Seki, E., De Minicis, S., Gwak, G.Y., et al. CCR1 and CCR5 promote hepatic fibrosis in mice. J Clin Invest 119 (2009), 1858–1870.
    • (2009) J Clin Invest , vol.119 , pp. 1858-1870
    • Seki, E.1    De Minicis, S.2    Gwak, G.Y.3
  • 19
    • 78049415469 scopus 로고    scopus 로고
    • Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice
    • 19 Berres, M.L., Koenen, R.R., Rueland, A., et al. Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice. The J Clin Invest 120 (2010), 4129–4140.
    • (2010) The J Clin Invest , vol.120 , pp. 4129-4140
    • Berres, M.L.1    Koenen, R.R.2    Rueland, A.3
  • 20
    • 33847280286 scopus 로고    scopus 로고
    • T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity
    • 20 Wu, H., Ghosh, S., Perrard, X.D., et al. T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity. Circulation 115 (2007), 1029–1038.
    • (2007) Circulation , vol.115 , pp. 1029-1038
    • Wu, H.1    Ghosh, S.2    Perrard, X.D.3
  • 21
    • 77956093740 scopus 로고    scopus 로고
    • Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation
    • 21 Kirovski, G., Gabele, E., Dorn, C., et al. Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation. Int J Clin Exp Pathol 3 (2010), 675–680.
    • (2010) Int J Clin Exp Pathol , vol.3 , pp. 675-680
    • Kirovski, G.1    Gabele, E.2    Dorn, C.3
  • 22
    • 84861591910 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological association, American association for the study of liver diseases, and American College of Gastroenterology
    • 22 Chalasani, N., Younossi, Z., Lavine, J.E., et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological association, American association for the study of liver diseases, and American College of Gastroenterology. Gastroenterology 142 (2012), 1592–1609.
    • (2012) Gastroenterology , vol.142 , pp. 1592-1609
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3
  • 23
    • 84899431637 scopus 로고    scopus 로고
    • Effect of ambrex (a herbal formulation) on oxidative stress in hyperlipidemic rats and differentiation of 3T3-L1 preadipocytes
    • 23 Devi, A.J., Ravindran, R., Sankar, M., Rajkumar, J., Effect of ambrex (a herbal formulation) on oxidative stress in hyperlipidemic rats and differentiation of 3T3-L1 preadipocytes. Pharmacogn Mag 10 (2014), 165–171.
    • (2014) Pharmacogn Mag , vol.10 , pp. 165-171
    • Devi, A.J.1    Ravindran, R.2    Sankar, M.3    Rajkumar, J.4
  • 24
    • 0035336310 scopus 로고    scopus 로고
    • CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells
    • 24 Schwabe, R.F., Schnabl, B., Kweon, Y.O., Brenner, D.A., CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. J Immunol 166 (2001), 6812–6819.
    • (2001) J Immunol , vol.166 , pp. 6812-6819
    • Schwabe, R.F.1    Schnabl, B.2    Kweon, Y.O.3    Brenner, D.A.4
  • 25
    • 84925946791 scopus 로고    scopus 로고
    • High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers
    • 25 Mederacke, I., Dapito, D.H., Affo, S., Uchinami, H., Schwabe, R.F., High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers. Nat Protoc 10 (2015), 305–315.
    • (2015) Nat Protoc , vol.10 , pp. 305-315
    • Mederacke, I.1    Dapito, D.H.2    Affo, S.3    Uchinami, H.4    Schwabe, R.F.5
  • 26
    • 84905915688 scopus 로고    scopus 로고
    • Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica
    • 26 He, X., Pu, G., Tang, R., Zhang, D., Pan, W., Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica. PLoS One, 9, 2014, e104323.
    • (2014) PLoS One , vol.9 , pp. e104323
    • He, X.1    Pu, G.2    Tang, R.3    Zhang, D.4    Pan, W.5
  • 27
    • 0142244129 scopus 로고    scopus 로고
    • Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration
    • 27 Schwabe, R.F., Bataller, R., Brenner, D.A., Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration. Am J Physiol Gastrointest Liver Physiol 285 (2003), G949–G958.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285 , pp. G949-G958
    • Schwabe, R.F.1    Bataller, R.2    Brenner, D.A.3
  • 28
    • 0038724267 scopus 로고    scopus 로고
    • Fetal liver stroma consists of cells in epithelial-to-mesenchymal transition
    • 28 Chagraoui, J., Lepage-Noll, A., Anjo, A., Uzan, G., Charbord, P., Fetal liver stroma consists of cells in epithelial-to-mesenchymal transition. Blood 101 (2003), 2973–2982.
    • (2003) Blood , vol.101 , pp. 2973-2982
    • Chagraoui, J.1    Lepage-Noll, A.2    Anjo, A.3    Uzan, G.4    Charbord, P.5
  • 29
    • 79951964804 scopus 로고    scopus 로고
    • Acetic acid treatment for wrinkle-free oral mucosal epithelia in paraffin section preparation
    • 29 Ahsan, M.S., Maruyama, S., Cheng, J., et al. Acetic acid treatment for wrinkle-free oral mucosal epithelia in paraffin section preparation. Microsc Res Tech 74 (2011), 264–268.
    • (2011) Microsc Res Tech , vol.74 , pp. 264-268
    • Ahsan, M.S.1    Maruyama, S.2    Cheng, J.3
  • 30
    • 0034055372 scopus 로고    scopus 로고
    • Localization of enteroviral antigen in myocardium and other tissues from patients with heart muscle disease by an improved immunohistochemical technique
    • 30 Zhang, H., Li, Y., Peng, T., et al. Localization of enteroviral antigen in myocardium and other tissues from patients with heart muscle disease by an improved immunohistochemical technique. J Histochem Cytochem 48 (2000), 579–584.
    • (2000) J Histochem Cytochem , vol.48 , pp. 579-584
    • Zhang, H.1    Li, Y.2    Peng, T.3
  • 31
    • 84906794667 scopus 로고    scopus 로고
    • E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network
    • 31 Zhang, Y., Xu, N., Xu, J., et al. E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network. Hepatology 60 (2014), 919–930.
    • (2014) Hepatology , vol.60 , pp. 919-930
    • Zhang, Y.1    Xu, N.2    Xu, J.3
  • 32
    • 0022178199 scopus 로고
    • Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results
    • 32 Loizou, S., McCrea, J.D., Rudge, A.C., Reynolds, R., Boyle, C.C., Harris, E.N., Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results. Clin Exp Immunol 62 (1985), 738–745.
    • (1985) Clin Exp Immunol , vol.62 , pp. 738-745
    • Loizou, S.1    McCrea, J.D.2    Rudge, A.C.3    Reynolds, R.4    Boyle, C.C.5    Harris, E.N.6
  • 33
    • 84927616700 scopus 로고    scopus 로고
    • Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer
    • 33 Liu, H., Lu, J., Hua, Y., et al. Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer. Cell Death Dis, 6, 2015, e1595.
    • (2015) Cell Death Dis , vol.6 , pp. e1595
    • Liu, H.1    Lu, J.2    Hua, Y.3
  • 34
    • 84872869007 scopus 로고    scopus 로고
    • Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation
    • 34 Sukhanova, A., Gorin, A., Serebriiskii, I.G., et al. Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation. Cancer Discov 3 (2013), 96–111.
    • (2013) Cancer Discov , vol.3 , pp. 96-111
    • Sukhanova, A.1    Gorin, A.2    Serebriiskii, I.G.3
  • 35
    • 83555173562 scopus 로고    scopus 로고
    • Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence
    • 35 Tu, Z., Aird, K.M., Bitler, B.G., et al. Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence. Dev Cell 21 (2011), 1077–1091.
    • (2011) Dev Cell , vol.21 , pp. 1077-1091
    • Tu, Z.1    Aird, K.M.2    Bitler, B.G.3
  • 36
    • 33846458253 scopus 로고    scopus 로고
    • Induction of cytochrome P450: assessment in an immortalized human hepatocyte cell line (Fa2N4) using a novel higher throughput cocktail assay
    • 36 Youdim, K.A., Tyman, C.A., Jones, B.C., Hyland, R., Induction of cytochrome P450: assessment in an immortalized human hepatocyte cell line (Fa2N4) using a novel higher throughput cocktail assay. Drug Metab Dispos 35 (2007), 275–282.
    • (2007) Drug Metab Dispos , vol.35 , pp. 275-282
    • Youdim, K.A.1    Tyman, C.A.2    Jones, B.C.3    Hyland, R.4
  • 37
    • 84892673575 scopus 로고    scopus 로고
    • Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes
    • 37 Egnatchik, R.A., Leamy, A.K., Noguchi, Y., Shiota, M., Young, J.D., Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes. Metab Clin Exp 63 (2014), 283–295.
    • (2014) Metab Clin Exp , vol.63 , pp. 283-295
    • Egnatchik, R.A.1    Leamy, A.K.2    Noguchi, Y.3    Shiota, M.4    Young, J.D.5
  • 38
    • 84866598263 scopus 로고    scopus 로고
    • Palmitate increases the susceptibility of cells to drug-induced toxicity: an in vitro method to identify drugs with potential contraindications in patients with metabolic disease
    • 38 Luo, Y., Rana, P., Will, Y., Palmitate increases the susceptibility of cells to drug-induced toxicity: an in vitro method to identify drugs with potential contraindications in patients with metabolic disease. Toxicol Sci 129 (2012), 346–362.
    • (2012) Toxicol Sci , vol.129 , pp. 346-362
    • Luo, Y.1    Rana, P.2    Will, Y.3
  • 39
    • 84959487714 scopus 로고    scopus 로고
    • (99m)Tc-labelled anti-CD11b SPECT/CT imaging allows detection of plaque destabilization tightly linked to inflammation
    • 39 Liu, G., Hu, Y., Xiao, J., et al. (99m)Tc-labelled anti-CD11b SPECT/CT imaging allows detection of plaque destabilization tightly linked to inflammation. Sci Rep, 6, 2016, 20900.
    • (2016) Sci Rep , vol.6 , pp. 20900
    • Liu, G.1    Hu, Y.2    Xiao, J.3
  • 40
    • 84966552441 scopus 로고    scopus 로고
    • Effects of Tanshinone IIA on the modulation of miR33a and the SREBP2/Pcsk9 signaling pathway in hyperlipidemic rats
    • 40 Jia, L., Song, N., Yang, G., et al. Effects of Tanshinone IIA on the modulation of miR33a and the SREBP2/Pcsk9 signaling pathway in hyperlipidemic rats. Mol Med Rep 13 (2016), 4627–4635.
    • (2016) Mol Med Rep , vol.13 , pp. 4627-4635
    • Jia, L.1    Song, N.2    Yang, G.3
  • 41
    • 0036086409 scopus 로고    scopus 로고
    • Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases
    • 41 Muraoka, R.S., Dumont, N., Ritter, C.A., et al. Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest 109 (2002), 1551–1559.
    • (2002) J Clin Invest , vol.109 , pp. 1551-1559
    • Muraoka, R.S.1    Dumont, N.2    Ritter, C.A.3
  • 42
    • 84860217635 scopus 로고    scopus 로고
    • PDGF-induced migration of vascular smooth muscle cells is inhibited by heme oxygenase-1 via VEGFR2 upregulation and subsequent assembly of inactive VEGFR2/PDGFRbeta heterodimers
    • 42 Cheng, C., Haasdijk, R.A., Tempel, D., et al. PDGF-induced migration of vascular smooth muscle cells is inhibited by heme oxygenase-1 via VEGFR2 upregulation and subsequent assembly of inactive VEGFR2/PDGFRbeta heterodimers. Arterioscler Thromb Vasc Biol 32 (2012), 1289–1298.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1289-1298
    • Cheng, C.1    Haasdijk, R.A.2    Tempel, D.3
  • 43
    • 0030952324 scopus 로고    scopus 로고
    • Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts
    • 43 Cairns, J.A., Walls, A.F., Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J Clin Invest 99 (1997), 1313–1321.
    • (1997) J Clin Invest , vol.99 , pp. 1313-1321
    • Cairns, J.A.1    Walls, A.F.2
  • 44
    • 0032424386 scopus 로고    scopus 로고
    • Mast cell tryptase stimulates both human dermal fibroblast proliferation and type I collagen production
    • 44 Abe, M., Kurosawa, M., Ishikawa, O., Miyachi, Y., Kido, H., Mast cell tryptase stimulates both human dermal fibroblast proliferation and type I collagen production. Clin Exp Allergy 28 (1998), 1509–1517.
    • (1998) Clin Exp Allergy , vol.28 , pp. 1509-1517
    • Abe, M.1    Kurosawa, M.2    Ishikawa, O.3    Miyachi, Y.4    Kido, H.5
  • 45
    • 84866302126 scopus 로고    scopus 로고
    • Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA
    • 45 Pan, D., Coen, D.M., Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA. Proc Natl Acad Sci U S A 109 (2012), 14852–14857.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 14852-14857
    • Pan, D.1    Coen, D.M.2
  • 46
    • 84924043221 scopus 로고    scopus 로고
    • Rapid preparation of high-purity nuclear proteins from a small number of cultured cells for use in electrophoretic mobility shift assays
    • 46 Luo, Y., Hara, T., Ishido, Y., et al. Rapid preparation of high-purity nuclear proteins from a small number of cultured cells for use in electrophoretic mobility shift assays. BMC Immunol, 15, 2014, 62.
    • (2014) BMC Immunol , vol.15 , pp. 62
    • Luo, Y.1    Hara, T.2    Ishido, Y.3
  • 47
    • 84876431455 scopus 로고    scopus 로고
    • BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss
    • 47 Tu, Z., Zhuang, X., Yao, Y.G., Zhang, R., BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss. Mol Cell Biol 33 (2013), 1819–1829.
    • (2013) Mol Cell Biol , vol.33 , pp. 1819-1829
    • Tu, Z.1    Zhuang, X.2    Yao, Y.G.3    Zhang, R.4
  • 49
    • 84862832781 scopus 로고    scopus 로고
    • CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5
    • 49 Pham, K., Luo, D., Liu, C., Harrison, J.K., CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5. J Neuroimmunol 246 (2012), 10–17.
    • (2012) J Neuroimmunol , vol.246 , pp. 10-17
    • Pham, K.1    Luo, D.2    Liu, C.3    Harrison, J.K.4
  • 50
    • 46249130838 scopus 로고    scopus 로고
    • Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways
    • 50 Wu, X., Zhang, L., Gurley, E., et al. Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways. Hepatology 47 (2008), 1905–1915.
    • (2008) Hepatology , vol.47 , pp. 1905-1915
    • Wu, X.1    Zhang, L.2    Gurley, E.3
  • 51
    • 84881609950 scopus 로고    scopus 로고
    • Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity
    • 51 Geng, T., Hu, W., Broadwater, M.H., et al. Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity. Diabetologia 56 (2013), 2078–2087.
    • (2013) Diabetologia , vol.56 , pp. 2078-2087
    • Geng, T.1    Hu, W.2    Broadwater, M.H.3
  • 52
    • 35948978184 scopus 로고    scopus 로고
    • Hepatic fibrogenesis
    • 52 Guo, J., Friedman, S.L., Hepatic fibrogenesis. Semin Liver Dis 27 (2007), 413–426.
    • (2007) Semin Liver Dis , vol.27 , pp. 413-426
    • Guo, J.1    Friedman, S.L.2
  • 53
    • 17144395561 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10
    • 53 Zheng, W.D., Zhang, L.J., Shi, M.N., et al. Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10. World J Gastroenterol 11 (2005), 1753–1758.
    • (2005) World J Gastroenterol , vol.11 , pp. 1753-1758
    • Zheng, W.D.1    Zhang, L.J.2    Shi, M.N.3
  • 54
    • 33846209631 scopus 로고    scopus 로고
    • Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway
    • 54 Shi, Y.F., Fong, C.C., Zhang, Q., et al. Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway. FEBS Lett 581 (2007), 203–210.
    • (2007) FEBS Lett , vol.581 , pp. 203-210
    • Shi, Y.F.1    Fong, C.C.2    Zhang, Q.3
  • 55
    • 84885081819 scopus 로고    scopus 로고
    • Activated effects of parathyroid hormone-related protein on human hepatic stellate cells
    • 55 Liang, F.F., Liu, C.P., Li, L.X., et al. Activated effects of parathyroid hormone-related protein on human hepatic stellate cells. PLoS One, 8, 2013, e76517.
    • (2013) PLoS One , vol.8 , pp. e76517
    • Liang, F.F.1    Liu, C.P.2    Li, L.X.3
  • 57
    • 84933059655 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta in relation to ER stress, inflammation, and metabolic disturbances
    • 57 van der Krieken, S.E., Popeijus, H.E., Mensink, R.P., Plat, J., CCAAT/enhancer binding protein beta in relation to ER stress, inflammation, and metabolic disturbances. Biomed Res Int, 2015, 2015, 324815.
    • (2015) Biomed Res Int , vol.2015 , pp. 324815
    • van der Krieken, S.E.1    Popeijus, H.E.2    Mensink, R.P.3    Plat, J.4
  • 58
    • 0026501412 scopus 로고
    • Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
    • 58 Natsuka, S., Akira, S., Nishio, Y., et al. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6. Blood 79 (1992), 460–466.
    • (1992) Blood , vol.79 , pp. 460-466
    • Natsuka, S.1    Akira, S.2    Nishio, Y.3
  • 59
    • 0033982578 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins
    • 59 Greenwel, P., Tanaka, S., Penkov, D., et al. Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins. Mol Cell Biol 20 (2000), 912–918.
    • (2000) Mol Cell Biol , vol.20 , pp. 912-918
    • Greenwel, P.1    Tanaka, S.2    Penkov, D.3
  • 60
    • 0035291240 scopus 로고    scopus 로고
    • Molecular and in silico characterization of a promoter module and C/EBP element that mediate LPS-induced RANTES/CCL5 expression in monocytic cells
    • 60 Fessele, S., Boehlk, S., Mojaat, A., et al. Molecular and in silico characterization of a promoter module and C/EBP element that mediate LPS-induced RANTES/CCL5 expression in monocytic cells. FASEB J 15 (2001), 577–579.
    • (2001) FASEB J , vol.15 , pp. 577-579
    • Fessele, S.1    Boehlk, S.2    Mojaat, A.3
  • 61
    • 84902435362 scopus 로고    scopus 로고
    • Maraviroc, a CCR5 antagonist, ameliorates the development of hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD)
    • 61 Perez-Martinez, L., Perez-Matute, P., Aguilera-Lizarraga, J., et al. Maraviroc, a CCR5 antagonist, ameliorates the development of hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD). J Antimicrob Chemother 69 (2014), 1903–1910.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1903-1910
    • Perez-Martinez, L.1    Perez-Matute, P.2    Aguilera-Lizarraga, J.3
  • 62
    • 0036785289 scopus 로고    scopus 로고
    • CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor
    • 62 Honczarenko, M., Le, Y., Glodek, A.M., et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood 100 (2002), 2321–2329.
    • (2002) Blood , vol.100 , pp. 2321-2329
    • Honczarenko, M.1    Le, Y.2    Glodek, A.M.3
  • 63
    • 77954971781 scopus 로고    scopus 로고
    • Cenicriviroc, an orally active CCR5 antagonist for the potential treatment of HIV infection
    • 63 Klibanov, O.M., Williams, S.H., Iler, C.A., Cenicriviroc, an orally active CCR5 antagonist for the potential treatment of HIV infection. Curr Opin Investig Drugs 11 (2010), 940–950.
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 940-950
    • Klibanov, O.M.1    Williams, S.H.2    Iler, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.