E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network

Hepatology

Volumn 60, Issue 3, 2014, Pages 919-930

  Zhang, Yuxia ^a   Xu, Ningyi ^b   Xu, Jun ^a,c   Kong, Bo ^d   Copple, Bryan ^e   Guo, Grace L ^d   Wang, Li ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c HENAN AGRICULTURAL UNIVERSITY   (China)

^d RUTGERS UNIVERSITY   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; 3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; BILE ACID; CELL NUCLEUS RECEPTOR; CHENDEOXYCHOLIC ACID; CHOLESTEROL; CHOLIC ACID; COLLAGEN; COLLAGEN ALPHA1 CHAIN; EARLY GROWTH RESPONSE FACTOR 1; EIA LIKE INHIBITOR OF DIFFERENTIATION 1; FATTY ACID; INHIBITOR OF DIFFERENTIATION 1; INTERCELLULAR ADHESION MOLECULE 1; LINOLEIC ACID; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NUCLEAR RECEPTOR SMALL HETERODIMER PARTNER; OLEIC ACID; PALMITIC ACID; ROSIGLITAZONE; STEARIC ACID; TRANSCRIPTION FACTOR E2F1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER CIRRHOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE ACID BLOOD LEVEL; BILE ACID METABOLISM; BILE DUCT; BILE DUCT INJURY; BILE DUCT LIGATION; CHOLESTATIC LIVER FIBROSIS; CONTROLLED STUDY; DNA FLANKING REGION; DOWN REGULATION; EARLY RESPONSE GENE; ENZYME ASSAY; EPITHELIUM CELL; FEEDING; GENE CONTROL; GENE EXPRESSION; GENE REGULATORY NETWORK; GLUTATHIONE S TRANSFERASE PULL DOWN ASSAY; HUMAN; IMMUNOHISTOCHEMISTRY; LIPID STORAGE; LIVER; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; LIVER NECROSIS; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STAINING; STELLATE CELL; UPREGULATION;

ANIMALS; CHOLESTASIS; E2F1 TRANSCRIPTION FACTOR; EARLY GROWTH RESPONSE PROTEIN 1; GENE REGULATORY NETWORKS; HEPATOCYTES; HUMANS; LIVER CIRRHOSIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PYRIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS;

EID: 84906794667     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27121     Document Type: Article

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