Persistent Microvascular Obstruction after Myocardial Infarction Culminates in the Confluence of Ferric Iron Oxide Crystals, Proinflammatory Burden, and Adverse Remodeling

Circulation: Cardiovascular Imaging

Volumn 9, Issue 11, 2016, Pages

  Kali, Avinash ^a,b   Cokic, Ivan ^a   Tang, Richard ^a   Dohnalkova, Alice ^c   Kovarik, Libor ^c   Yang, Hsin Jung ^a,b   Kumar, Andreas ^a   Prato, Frank S ^d   Wood, John C ^e   Underhill, David ^a,b   Marbán, Eduardo ^a,b   Dharmakumar, Rohan ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

Cytokines; hemorrhage; inflammation; iron ischemia reperfusion injury; myocardial infarction

Indexed keywords

CYTOKINE; FERRIC OXIDE; GELATINASE B; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; NANOCRYSTAL; TUMOR NECROSIS FACTOR; AUTACOID; FERRIC ION;

ADVERSE OUTCOME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL OCCLUSION; CARDIOVASCULAR MAGNETIC RESONANCE; CELL INFILTRATION; CHEMICAL COMPOSITION; COLLAGEN DEGRADATION; CONTROLLED STUDY; CRYSTAL; CRYSTALLIZATION; CYTOKINE PRODUCTION; DOG; ENERGY DISPERSIVE X RAY SPECTROSCOPY; ENZYME ACTIVATION; HEART INFARCTION; HEART VENTRICLE REMODELING; HISTOPATHOLOGY; INFLAMMATION; MACROPHAGE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; PARTICLE SIZE; PERSISTENT MICROVASCULAR OBSTRUCTION; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CARDIAC MUSCLE; COMPLICATION; CORONARY ARTERY BLOOD FLOW; DISEASE MODEL; HEART LEFT VENTRICLE FUNCTION; METABOLISM; MICROCIRCULATION; MYOCARDIAL REPERFUSION INJURY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; SPECTROMETRY; TIME FACTOR;

ANIMALS; CORONARY CIRCULATION; CRYSTALLIZATION; DISEASE MODELS, ANIMAL; DOGS; FERRIC COMPOUNDS; INFLAMMATION MEDIATORS; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MICROCIRCULATION; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; SPECTROMETRY, X-RAY EMISSION; TIME FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84995743487     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.115.004996     Document Type: Article

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