The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6

Molecular Cell

Volumn 64, Issue 4, 2016, Pages 815-825

  Van Oss, S Branden ^a   Shirra, Margaret K ^a   Bataille, Alain R ^b   Wier, Adam D ^a   Yen, Kuangyu ^b,c   Vinayachandran, Vinesh ^b   Byeon, In Ja L ^d   Cucinotta, Christine E ^a   Héroux, Annie ^e   Jeon, Jongcheol ^f   Kim, Jaehoon ^f   VanDemark, Andrew P ^a   Pugh, B Franklin ^b   Arndt, Karen M ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e BROOKHAVEN NATIONAL LABORATORY   (United States)

^f Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Bre1; chromatin; H2B ubiquitylation; histone modifications; Paf1 complex; Rad6; RNA Polymerase II; Rtf1; transcription elongation

Indexed keywords

FUNGAL PROTEIN; HISTONE H2B; PAF1 COMPLEX SUBUNIT RTF1; UBIQUITIN CONJUGASE RAD6; UNCLASSIFIED DRUG; BRE1 PROTEIN, S CEREVISIAE; CROSS LINKING REAGENT; FORMALDEHYDE; HISTONE; NONHISTONE PROTEIN; NUCLEAR PROTEIN; PROTEIN BINDING; RAD6 PROTEIN, S CEREVISIAE; RECOMBINANT PROTEIN; RNA POLYMERASE II; RTF1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SPT4 PROTEIN, S CEREVISIAE; SPT5 TRANSCRIPTIONAL ELONGATION FACTOR; TATA BINDING PROTEIN; TRANSCRIPTION ELONGATION FACTOR; UBIQUITIN CONJUGATING ENZYME;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HISTONE UBIQUITINATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; ALPHA HELIX; BINDING SITE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; UBIQUITINATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; BINDING SITES; CHROMOSOMAL PROTEINS, NON-HISTONE; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; FORMALDEHYDE; GENE EXPRESSION REGULATION, FUNGAL; HISTONES; MODELS, MOLECULAR; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TATA-BOX BINDING PROTEIN; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ELONGATION FACTORS; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84995646150     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.10.008     Document Type: Article

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