Tenuifolide B from Cinnamomum tenuifolium stem selectively inhibits proliferation of oral cancer cells via apoptosis, ROS generation, mitochondrial depolarization, and DNA damage

Toxins

Volumn 8, Issue 11, 2016, Pages

  Chen, Chung Yi ^a   Yen, Ching Yu ^b,c   Wang, Hui Ru ^d   Yang, Hui Ping ^e   Tang, Jen Yang ^e,f,g   Huang, Hurng Wern ^h   Hsu, Shih Hsien ^e   Chang, Hsueh Wei ^d,f,h  

^a FOOYIN UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^f KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g KAOHSIUNG MUNICIPAL TA TUNG HOSPITAL   (Taiwan)

^h NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; DNA damage; Natural product; Oral cancer; ROS; Selective killing

Indexed keywords

CASPASE; CINNAMOMUM TENUIFOLIUM EXTRACT; LIPOCORTIN 5; PLANT EXTRACT; TENUIFOLIDE B; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; GAMMA BUTYROLACTONE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL VIABILITY; DNA DAMAGE; FLOW CYTOMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUTH CANCER; NONHUMAN; OXIDATIVE STRESS; PLANT STEM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; CINNAMOMUM; DRUG EFFECTS; HUMAN; METABOLISM; MOUTH NEOPLASMS; TUMOR CELL LINE;

4-BUTYROLACTONE; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CINNAMOMUM; DNA DAMAGE; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOUTH NEOPLASMS; PLANT STEMS; REACTIVE OXYGEN SPECIES;

EID: 84995611269     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins8110319     Document Type: Article

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