Transcriptional profiling of foam cells reveals induction of guanylate-binding proteins following western diet acceleration of atherosclerosis in the absence of global changes in inflammation

Journal of the American Heart Association

Volumn 5, Issue 4, 2016, Pages

  Goo, Young Hwa ^a   Son, Se Hee ^a   Yechoor, Vijay K ^b   Paul, Antoni ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Cholesterol; Gene expression; Inflammation; Macrophages

Indexed keywords

CXCL13 CHEMOKINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN 3; GUANINE NUCLEOTIDE BINDING PROTEIN 6; UNCLASSIFIED DRUG; LIPID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOAM CELL; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYPERCHOLESTEROLEMIA; IMMUNE RESPONSE; IN VIVO STUDY; LASER MICRODISSECTION; LIPID STORAGE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; WESTERN DIET; ADVERSE EFFECTS; ANIMAL; AORTIC SINUS; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INFLAMMATION; KNOCKOUT MOUSE; LASER CAPTURE MICRODISSECTION; PATHOPHYSIOLOGY;

ANIMALS; ATHEROSCLEROSIS; DIET, WESTERN; FEMALE; FOAM CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; INFLAMMATION; LASER CAPTURE MICRODISSECTION; LIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SINUS OF VALSALVA;

EID: 84995607515     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.002663     Document Type: Article

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