Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41

Physiological Genomics

Volumn 48, Issue 11, 2016, Pages 826-834

  Natarajan, Niranjana ^a   Hori, Daijiro ^a   Flavahan, Sheila ^a   Steppan, Jochen ^a   Flavahan, Nicholas A ^a   Berkowitz, Dan E ^a   Pluznick, Jennifer L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetate; Endothelium; GPCR; Hypertension; Microbiota; Propionate

Indexed keywords

ACETIC ACID; COLLAGEN; ELASTIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 41; PROPIONIC ACID; RENIN; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG; GPCR41 PROTEIN, MOUSE; VOLATILE FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL STIFFNESS; ARTICLE; BLOOD PRESSURE REGULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EX VIVO STUDY; FEMALE; MALE; MEAN ARTERIAL PRESSURE; METABOLITE; MICROBIAL METABOLISM; MOUSE; MYOGRAPHY; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PULSE WAVE; RESISTANCE BLOOD VESSEL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; SYSTOLIC HYPERTENSION; VASCULAR ENDOTHELIUM; ANIMAL; BACTERIUM; BLOOD; BLOOD PRESSURE; C57BL MOUSE; DRUG EFFECTS; HYPERTENSION; KNOCKOUT MOUSE; METABOLISM; METABOLOME; PATHOPHYSIOLOGY; PIG; SALT INTAKE; SYSTOLE; VASODILATATION;

ANIMALS; BACTERIA; BLOOD PRESSURE; ENDOTHELIUM, VASCULAR; FATTY ACIDS, VOLATILE; FEMALE; HYPERTENSION; MALE; METABOLOME; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; RENIN; SODIUM CHLORIDE, DIETARY; SUS SCROFA; SYSTOLE; VASODILATION;

EID: 84995579577     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00089.2016     Document Type: Article

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