Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

Nature Communications

Volumn 7, Issue , 2016, Pages

  Phoo, Wint Wint ^a,b,c   Li, Yan ^d   Zhang, Zhenzhen ^a,c   Lee, Michelle Yueqi ^d   Loh, Ying Ru ^d   Tan, Yaw Bia ^a,c   Ng, Elizabeth Yihui ^d   Lescar, Julien ^b,c   Kang, Congbao ^d   Luo, Dahai ^a,b,c  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^d Agency for Science   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTRUCTURAL PROTEIN 2B; NONSTRUCTURAL PROTEIN 3; POLYPROTEIN; PROTEASE INHIBITOR BPTI; PROTEINASE; PROTEINASE INHIBITOR; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; PEPTIDE HYDROLASE; PROTEIN BINDING; VIRAL PROTEIN;

AMINO ACID; CRYSTAL STRUCTURE; NUCLEAR MAGNETIC RESONANCE; POPULATION OUTBREAK; PROTEIN; PUBLIC HEALTH; SUBSTRATE; VIRAL DISEASE; VIRUS;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME STRUCTURE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; ZIKA VIRUS; BINDING SITE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

NORTH AMERICA; SOUTH AMERICA;

FLAVIVIRUS; ZIKA VIRUS;

BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEOLYSIS; VIRAL NONSTRUCTURAL PROTEINS; ZIKA VIRUS;

EID: 84995466578     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13410     Document Type: Article

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