메뉴 건너뛰기




Volumn 15, Issue 11, 2016, Pages 3412-3423

Comprehensive proteomic analysis of human milk-derived extracellular vesicles unveils a novel functional proteome distinct from other milk components

Author keywords

[No Author keywords available]

Indexed keywords

CD9 ANTIGEN; FLOTILLIN 1; LIPOCORTIN 5; MILK PROTEIN; PROTEOME;

EID: 84995451818     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M116.060426     Document Type: Article
Times cited : (127)

References (45)
  • 1
    • 33846953590 scopus 로고    scopus 로고
    • Protection of the neonate by the innate immune system of developing gut and of human milk
    • Newburg, D. S., and Walker, W. A. (2007) Protection of the neonate by the innate immune system of developing gut and of human milk. Pediatr. Res. 61, 2-8
    • (2007) Pediatr. Res. , vol.61 , pp. 2-8
    • Newburg, D.S.1    Walker, W.A.2
  • 2
    • 38949191258 scopus 로고    scopus 로고
    • Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma
    • Verhasselt, V., Milcent, V., and Cazareth, J. (2008) Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma. Nat. Med. 14, 170-175
    • (2008) Nat. Med. , vol.14 , pp. 170-175
    • Verhasselt, V.1    Milcent, V.2    Cazareth, J.3
  • 3
    • 11844294971 scopus 로고    scopus 로고
    • The immunological components of human milk and their effect on immune development in infants
    • Field, C. J. (2005) The immunological components of human milk and their effect on immune development in infants. J. Nutr. 135, 1-4
    • (2005) J. Nutr. , vol.135 , pp. 1-4
    • Field, C.J.1
  • 4
    • 0042326193 scopus 로고    scopus 로고
    • Breastfeeding and allergic disease: A multidisciplinary review of the literature (1966-2001) on the mode of early feeding in infancy and its impact on later atopic manifes-tations
    • van Odijk, J., Kull, I., and Borres, M. P. (2003) Breastfeeding and allergic disease: A multidisciplinary review of the literature (1966-2001) on the mode of early feeding in infancy and its impact on later atopic manifes-tations. Allergy 58, 833-843
    • (2003) Allergy , vol.58 , pp. 833-843
    • Van Odijk, J.1    Kull, I.2    Borres, M.P.3
  • 5
    • 84876263324 scopus 로고    scopus 로고
    • Cells in human milk: State of the science
    • Hassiotou, F., Geddes, D. T., and Hartmann, P. E. (2013) Cells in human milk: State of the science. J. Hum. Lact. 29, 171-182
    • (2013) J. Hum. Lact. , vol.29 , pp. 171-182
    • Hassiotou, F.1    Geddes, D.T.2    Hartmann, P.E.3
  • 6
    • 84869801840 scopus 로고    scopus 로고
    • Human milk composition: Nutrients and bioactive factors
    • Ballard, O., and Morrow, A. L. (2013) Human milk composition: Nutrients and bioactive factors. Pediatr. Clin. North Am. 60, 49-74
    • (2013) Pediatr. Clin. North Am. , vol.60 , pp. 49-74
    • Ballard, O.1    Morrow, A.L.2
  • 7
    • 84945481976 scopus 로고    scopus 로고
    • Human breast milk: A review on its composition and bioactivity
    • Andreas, N. J., Kampmann, B., and Mehring Le-Doare, K. (2015) Human breast milk: A review on its composition and bioactivity. Early Hum. Dev. 91, 629-635
    • (2015) Early Hum. Dev. , vol.91 , pp. 629-635
    • Andreas, N.J.1    Kampmann, B.2    Mehring Le-Doare, K.3
  • 8
    • 84899767554 scopus 로고    scopus 로고
    • Milk nutritional composition and its role in human health
    • Pereira, P. C. (2014) Milk nutritional composition and its role in human health. Nutrition 30, 619-627
    • (2014) Nutrition , vol.30 , pp. 619-627
    • Pereira, P.C.1
  • 9
    • 84906078613 scopus 로고    scopus 로고
    • Nature's first functional food
    • Gura, T. (2014) Nature's first functional food. Science 345, 747-749
    • (2014) Science , vol.345 , pp. 747-749
    • Gura, T.1
  • 10
    • 85015631965 scopus 로고    scopus 로고
    • Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures
    • eCollection 2014
    • Zonneveld, M. I., Brisson, A. R., and van Herwijnen, M. J. (2014) Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures. J. Extracell. Vesicles 3, 10.3402/jev.v3.24215. eCollection 2014
    • (2014) J. Extracell. Vesicles , pp. 3
    • Zonneveld, M.I.1    Brisson, A.R.2    Van Herwijnen, M.J.3
  • 11
    • 84895550556 scopus 로고    scopus 로고
    • Differences in exosome populations in human breast milk in relation to allergic sensitization and lifestyle
    • Torregrosa Paredes, P., Gutzeit, C., and Johansson, S. (2014) Differences in exosome populations in human breast milk in relation to allergic sensitization and lifestyle. Allergy 69, 463-471
    • (2014) Allergy , vol.69 , pp. 463-471
    • Torregrosa Paredes, P.1    Gutzeit, C.2    Johansson, S.3
  • 12
    • 34548619487 scopus 로고    scopus 로고
    • Exosomes with immune modulatory features are present in human breast milk
    • Admyre, C., Johansson, S. M., and Qazi, K. R. (2007) Exosomes with immune modulatory features are present in human breast milk. J. Immunol. 179, 1969-1978
    • (2007) J. Immunol. , vol.179 , pp. 1969-1978
    • Admyre, C.1    Johansson, S.M.2    Qazi, K.R.3
  • 13
    • 78651361232 scopus 로고    scopus 로고
    • Human saliva, plasma and breast milk exosomes contain RNA: Uptake by macrophages
    • Lasser, C., Alikhani, V. S., and Ekstrom, K. (2011) Human saliva, plasma and breast milk exosomes contain RNA: Uptake by macrophages. J. Transl. Med. 9, 9-5876-9-9
    • (2011) J. Transl. Med. , vol.9 , pp. 95876-958799
    • Lasser, C.1    Alikhani, V.S.2    Ekstrom, K.3
  • 15
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • Thery, C., Ostrowski, M., and Segura, E. (2009) Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol. 9, 581-593
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 581-593
    • Thery, C.1    Ostrowski, M.2    Segura, E.3
  • 16
    • 84949934993 scopus 로고    scopus 로고
    • As we wait: Coping with an imperfect nomenclature for extracellular vesicles
    • eCollection 2013
    • Gould, S. J., and Raposo, G. (2013) As we wait: Coping with an imperfect nomenclature for extracellular vesicles. J. Extracell. Vesicles 2, 10.3402/jev.v2i0.20389. eCollection 2013
    • (2013) J. Extracell. Vesicles , pp. 2
    • Gould, S.J.1    Raposo, G.2
  • 17
    • 85016448020 scopus 로고    scopus 로고
    • Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the international society for extracellular vesicles
    • Lötvall, J., Hill, A. F., and Hochberg, F. (2014) Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the international society for extracellular vesicles. J. Extracell. Vesicles 3, 26913
    • (2014) J. Extracell. Vesicles , vol.3 , pp. 26913
    • Lötvall, J.1    Hill, A.F.2    Hochberg, F.3
  • 18
    • 84860186326 scopus 로고    scopus 로고
    • Immune cell-derived vesicles: Modulators and mediators of inflammation
    • Nolte-'t Hoen, E. N., and and Wauben, M. H. (2012) Immune cell-derived vesicles: Modulators and mediators of inflammation. Curr. Pharm. Des. 18, 2357-2368
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 2357-2368
    • Nolte-'T Hoen, E.N.1    Wauben, M.H.2
  • 19
    • 83655181807 scopus 로고    scopus 로고
    • Immune-related microRNAs are abundant in breast milk exosomes
    • Zhou, Q., Li, M., and Wang, X. (2012) Immune-related microRNAs are abundant in breast milk exosomes. Int. J. Biol. Sci. 8, 118-123
    • (2012) Int. J. Biol. Sci. , vol.8 , pp. 118-123
    • Zhou, Q.1    Li, M.2    Wang, X.3
  • 20
    • 84976871411 scopus 로고    scopus 로고
    • 2016 update of the PRIDE database and its related tools
    • Vizcaino, J. A., Csordas, A., and del-Toro, N. (2016) 2016 update of the PRIDE database and its related tools. Nucleic Acids Res. 44, D447-D56
    • (2016) Nucleic Acids Res. , vol.44 , pp. D447-D456
    • Vizcaino, J.A.1    Csordas, A.2    Del-Toro, N.3
  • 21
    • 84938748671 scopus 로고    scopus 로고
    • FunRich: An open access standalone functional enrichment and interaction network analysis tool
    • Pathan, M., Keerthikumar, S., and Ang, C. S. (2015) FunRich: An open access standalone functional enrichment and interaction network analysis tool. Proteomics 15, 2597-2601
    • (2015) Proteomics , vol.15 , pp. 2597-2601
    • Pathan, M.1    Keerthikumar, S.2    Ang, C.S.3
  • 22
    • 84929657730 scopus 로고    scopus 로고
    • Comparative proteomics of human and macaque milk reveals species-specific nutrition during postnatal development
    • Beck, K. L., Weber, D., and Phinney, B. S. (2015) Comparative proteomics of human and macaque milk reveals species-specific nutrition during postnatal development. J. Proteome Res. 14, 2143-2157
    • (2015) J. Proteome Res. , vol.14 , pp. 2143-2157
    • Beck, K.L.1    Weber, D.2    Phinney, B.S.3
  • 23
    • 77954379514 scopus 로고    scopus 로고
    • Human milk proteins: An interactomics and updated functional overview
    • D'Alessandro, A., Scaloni, A., and Zolla, L. (2010) Human milk proteins: An interactomics and updated functional overview. J. Proteome Res. 9, 3339-3373
    • (2010) J. Proteome Res. , vol.9 , pp. 3339-3373
    • D'Alessandro, A.1    Scaloni, A.2    Zolla, L.3
  • 24
    • 84942683917 scopus 로고    scopus 로고
    • Leukocyte populations in human preterm and term breast milk identified by multicolour flow cy-tometry
    • Trend, S., de Jong, E., and Lloyd, M. L. (2015) Leukocyte populations in human preterm and term breast milk identified by multicolour flow cy-tometry. PLoS ONE 10, e0135580
    • (2015) PLoS ONE , vol.10 , pp. e0135580
    • Trend, S.1    De Jong, E.2    Lloyd, M.L.3
  • 25
    • 84871702725 scopus 로고    scopus 로고
    • Vesiclepedia: A compendium for extracellular vesicles with continuous community annotation
    • Kalra, H., Simpson, R. J., and Ji, H. (2012) Vesiclepedia: A compendium for extracellular vesicles with continuous community annotation. PLos Biol. 10, e1001450
    • (2012) PLos Biol. , vol.10 , pp. e1001450
    • Kalra, H.1    Simpson, R.J.2    Ji, H.3
  • 26
    • 0025924043 scopus 로고
    • Parathyroid hormone-related protein in milk and its correlation with bovine milk calcium
    • Law, F. M., Moate, P. J., and Leaver, D. D. (1991) Parathyroid hormone-related protein in milk and its correlation with bovine milk calcium. J. Endocrinol. 128, 21-26
    • (1991) J. Endocrinol. , vol.128 , pp. 21-26
    • Law, F.M.1    Moate, P.J.2    Leaver, D.D.3
  • 27
    • 84879045334 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns
    • Chatterton, D. E., Nguyen, D. N., and Bering, S. B. (2013) Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns. Int. J. Biochem. Cell Biol. 45, 1730-1747
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , pp. 1730-1747
    • Chatterton, D.E.1    Nguyen, D.N.2    Bering, S.B.3
  • 28
    • 84877136049 scopus 로고    scopus 로고
    • Extensive in vivo human milk peptidomics reveals specific proteolysis yielding protective antimi-crobial peptides
    • Dallas, D. C., Guerrero, A., and Khaldi, N. (2013) Extensive in vivo human milk peptidomics reveals specific proteolysis yielding protective antimi-crobial peptides. J. Proteome Res. 12, 2295-2304
    • (2013) J. Proteome Res. , vol.12 , pp. 2295-2304
    • Dallas, D.C.1    Guerrero, A.2    Khaldi, N.3
  • 29
    • 84924721660 scopus 로고    scopus 로고
    • Mechanistic peptidomics: Factors that dictate specificity in the formation of endogenous peptides in human milk
    • Guerrero, A., Dallas, D. C., and Contreras, S. (2014) Mechanistic peptidomics: Factors that dictate specificity in the formation of endogenous peptides in human milk. Mol. Cell. Proteomics 13, 3343-3351
    • (2014) Mol. Cell. Proteomics , vol.13 , pp. 3343-3351
    • Guerrero, A.1    Dallas, D.C.2    Contreras, S.3
  • 30
    • 84925849995 scopus 로고    scopus 로고
    • Difference in the breast milk proteome between allergic and non-allergic mothers
    • Hettinga, K. A., Reina, F. M., and Boeren, S. (2015) Difference in the breast milk proteome between allergic and non-allergic mothers. PLoS ONE 10, e0122234
    • (2015) PLoS ONE , vol.10 , pp. e0122234
    • Hettinga, K.A.1    Reina, F.M.2    Boeren, S.3
  • 31
    • 84858040906 scopus 로고    scopus 로고
    • Proteome profile and biological activity of caprine, bovine and human milk fat globules
    • Spertino, S., Cipriani, V., and De Angelis, C. (2012) Proteome profile and biological activity of caprine, bovine and human milk fat globules. Mol. Biosyst. 8, 967-974
    • (2012) Mol. Biosyst. , vol.8 , pp. 967-974
    • Spertino, S.1    Cipriani, V.2    De Angelis, C.3
  • 32
    • 84921451922 scopus 로고    scopus 로고
    • Proteomic characterization and comparison of mammalian milk fat globule proteomes by iTRAQ analy-sis
    • Yang, Y., Zheng, N., and Zhao, X. (2015) Proteomic characterization and comparison of mammalian milk fat globule proteomes by iTRAQ analy-sis. J. Proteomics 116, 34-43
    • (2015) J. Proteomics , vol.116 , pp. 34-43
    • Yang, Y.1    Zheng, N.2    Zhao, X.3
  • 33
    • 84943557780 scopus 로고    scopus 로고
    • Comparative proteomics of milk fat globule membrane in different species reveals variations in lactation and nutrition
    • Lu, J., Wang, X., and Zhang, W. (2016) Comparative proteomics of milk fat globule membrane in different species reveals variations in lactation and nutrition. Food Chem. 196, 665-672
    • (2016) Food Chem. , vol.196 , pp. 665-672
    • Lu, J.1    Wang, X.2    Zhang, W.3
  • 34
    • 85013222187 scopus 로고    scopus 로고
    • Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
    • eCollection 2013
    • Witwer, K. W., Buzas, E. I., and Bemis, L. T. (2013) Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J. Extracell. Vesicles 2, 10.3402/jev.v2i0.20360. eCollection 2013
    • (2013) J. Extracell. Vesicles , pp. 2
    • Witwer, K.W.1    Buzas, E.I.2    Bemis, L.T.3
  • 35
    • 85015684168 scopus 로고    scopus 로고
    • The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
    • eCollection 2014
    • Van Deun, J., Mestdagh, P., and Sormunen, R. (2014) The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. J. Extracell. Vesicles 3, 10.3402/jev.v3.24858. eCollection 2014
    • (2014) J. Extracell. Vesicles , pp. 3
    • Van Deun, J.1    Mestdagh, P.2    Sormunen, R.3
  • 36
    • 84863621039 scopus 로고    scopus 로고
    • Temporal changes in milk proteomes reveal developing milk functions
    • Gao, X., McMahon, R. J., and Woo, J. G. (2012) Temporal changes in milk proteomes reveal developing milk functions. J. Proteome Res. 11, 3897-3907
    • (2012) J. Proteome Res. , vol.11 , pp. 3897-3907
    • Gao, X.1    McMahon, R.J.2    Woo, J.G.3
  • 37
    • 79961232783 scopus 로고    scopus 로고
    • Proteomic characterization of human milk fat globule membrane proteins during a 12 month lactation period
    • Liao, Y., Alvarado, R., and Phinney, B. (2011) Proteomic characterization of human milk fat globule membrane proteins during a 12 month lactation period. J. Proteome Res. 10, 3530-3541
    • (2011) J. Proteome Res. , vol.10 , pp. 3530-3541
    • Liao, Y.1    Alvarado, R.2    Phinney, B.3
  • 38
    • 79953697144 scopus 로고    scopus 로고
    • Proteomic characterization of human milk whey proteins during a twelve-month lactation period
    • Liao, Y., Alvarado, R., and Phinney, B. (2011) Proteomic characterization of human milk whey proteins during a twelve-month lactation period. J. Proteome Res. 10, 1746-1754
    • (2011) J. Proteome Res. , vol.10 , pp. 1746-1754
    • Liao, Y.1    Alvarado, R.2    Phinney, B.3
  • 39
    • 84896860378 scopus 로고    scopus 로고
    • Impact of maternal diet on human milk composition and neurological development of infants
    • Innis, S. M. (2014) Impact of maternal diet on human milk composition and neurological development of infants. Am. J. Clin. Nutr. 99:734S-41S
    • (2014) Am. J. Clin. Nutr. , vol.99 , pp. 734S
    • Innis, S.M.1
  • 40
    • 0015415502 scopus 로고
    • Lactation patterns in egyptian women. II. Chemical composition of milk during the first year of lactation
    • Kader, M. M., Bahgat, R., and Aziz, M. T. (1972) Lactation patterns in egyptian women. II. chemical composition of milk during the first year of lactation. J. Biosoc. Sci. 4, 403-409
    • (1972) J. Biosoc. Sci. , vol.4 , pp. 403-409
    • Kader, M.M.1    Bahgat, R.2    Aziz, M.T.3
  • 41
    • 80053898302 scopus 로고    scopus 로고
    • Identification of a conserved glycan signature for microvesicles
    • Batista, B. S., Eng, W. S., and Pilobello, K. T. (2011) Identification of a conserved glycan signature for microvesicles. J. Proteome Res. 10, 4624-4633
    • (2011) J. Proteome Res. , vol.10 , pp. 4624-4633
    • Batista, B.S.1    Eng, W.S.2    Pilobello, K.T.3
  • 42
    • 79955702185 scopus 로고    scopus 로고
    • The host defense proteome of human and bovine milk
    • Hettinga, K., van Valenberg, H., and de Vries, S. (2011) The host defense proteome of human and bovine milk. PLoS ONE 6, e19433
    • (2011) PLoS ONE , vol.6 , pp. e19433
    • Hettinga, K.1    Van Valenberg, H.2    De Vries, S.3
  • 43
    • 84890065017 scopus 로고    scopus 로고
    • Elevated concentrations of milk beta2-microglobulin are associated with increased risk of breastfeeding transmission of HIV-1 (vertical transmission study)
    • Mange, A., Tuaillon, E., and Viljoen, J. (2013) Elevated concentrations of milk beta2-microglobulin are associated with increased risk of breastfeeding transmission of HIV-1 (vertical transmission study). J. Proteome Res. 12, 5616-5625
    • (2013) J. Proteome Res. , vol.12 , pp. 5616-5625
    • Mange, A.1    Tuaillon, E.2    Viljoen, J.3
  • 44
    • 84857842309 scopus 로고    scopus 로고
    • Proteome mapping of human skim milk proteins in term and preterm milk
    • Molinari, C. E., Casadio, Y. S., and Hartmann, B. T. (2012) Proteome mapping of human skim milk proteins in term and preterm milk. J. Proteome Res. 11, 1696-1714
    • (2012) J. Proteome Res. , vol.11 , pp. 1696-1714
    • Molinari, C.E.1    Casadio, Y.S.2    Hartmann, B.T.3
  • 45
    • 84893863185 scopus 로고    scopus 로고
    • Quantitative analysis of the human milk whey proteome reveals developing milk and mamma-ry-gland functions across the first year of lactation
    • Zhang, Q., Cundiff, J. K., and Maria, S. D. (2013) Quantitative analysis of the human milk whey proteome reveals developing milk and mamma-ry-gland functions across the first year of lactation. Proteomes 1, 128-158
    • (2013) Proteomes , vol.1 , pp. 128-158
    • Zhang, Q.1    Cundiff, J.K.2    Maria, S.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.