Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae

Metabolic Engineering

Volumn 38, Issue , 2016, Pages 494-503

  Kirby, James ^b,c   Dietzel, Kevin L ^a   Wichmann, Gale ^a   Chan, Rossana ^b,c   Antipov, Eugene ^a   Moss, Nathan ^a   Baidoo, Edward E K ^c   Jackson, Peter ^a   Gaucher, Sara P ^a   Gottlieb, Shayin ^a   LaBarge, Jeremy ^a   Mahatdejkul, Tina ^a   Hawkins, Kristy M ^a   Muley, Sheela ^a   Newman, Jack D ^a   Liu, Pinghua ^d   Keasling, Jay D ^b,c,e,f,g   Zhao, Lishan ^a  

^a Amyris Inc   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JOINT BIOENERGY INSTITUTE   (United States)

^d USA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^g Chalmers University of Technology   (Denmark)

Author keywords

MEP pathway; metabolic engineering; terpene; yeast

Indexed keywords

BIOCHEMISTRY; LIPIDS; METABOLIC ENGINEERING; TERPENES;

COMMERCIAL APPLICATIONS; ENGINEERED STRAINS; EUKARYOTIC CYTOSOL; FUNCTIONAL EXPRESSION; ISOPRENOID BIOSYNTHESIS; MEP PATHWAYS; MEVALONATE PATHWAY; THEORETICAL YIELD;

YEAST;

1 DEOXY DEXTRO XYLULOSE 5 PHOSPHATE; 2 C METHYL DEXTRO ERYTHRITOL 2,4 CYCLODIPHOSPHATE REDUCTASE; 4 HYDROXYL 3 METHYLBUT 2 ENYL DIPHOSPHATE REDUCTASE; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; FLAVODOXIN; ISOPRENOID; MEVALONIC ACID; OXIDOREDUCTASE; PHOSPHATE; UNCLASSIFIED DRUG; 1-DEOXYLULOSE 5-PHOSPHATE; PENTOSE PHOSPHATE; TERPENE;

ARTICLE; BIOSYNTHESIS; FUNGAL BIOMASS; FUNGAL STRAIN; FUNGUS GROWTH; IN VITRO STUDY; METABOLIC ENGINEERING; METABOLOMICS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SYNTHETIC BIOLOGY; GENETICS; METABOLISM;

METABOLIC ENGINEERING; PENTOSEPHOSPHATES; SACCHAROMYCES CEREVISIAE; TERPENES;

EID: 84994852889     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2016.10.017     Document Type: Article

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