B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation

Cardiovascular Research

Volumn 111, Issue 4, 2016, Pages 385-397

  Tay, Christopher ^a,b   Liu, Yu Han ^a   Hosseini, Hamid ^a,b   Kanellakis, Peter ^a   Cao, Anh ^a,b   Peter, Karlheinz ^a   Tipping, Peter ^b   Bobik, Alex ^a   Toh, Ban Hock ^b   Kyaw, Tin ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Apoptosis; Atherosclerosis; B2 cells; Inflammation; TNF

Indexed keywords

CHLORDANE; CHOLESTEROL; COLLAGENASE 3; DNA NUCLEOTIDYLEXOTRANSFERASE; FAS ANTIGEN; GAMMA INTERFERON; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR; APOLIPOPROTEIN E;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CHIMERA; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMORAL IMMUNE DEFICIENCY; HUMORAL IMMUNITY; HYPERLIPIDEMIA; IMMUNOFLUORESCENCE; INFLAMMATION; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; SPLEEN LYMPHOCYTE; TUNEL ASSAY; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; AORTA; ATHEROSCLEROSIS; B LYMPHOCYTE; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM;

ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; B-LYMPHOCYTES; CELL DEATH; DIET, HIGH-FAT; INFLAMMATION; MACROPHAGES; MICE, KNOCKOUT; PLAQUE, ATHEROSCLEROTIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84994824076     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvw186     Document Type: Article

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