Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions

Nature Biotechnology

Volumn 34, Issue 11, 2016, Pages 1180-1190

  Ernst, Jason ^a,b,c   Melnikov, Alexandre ^d   Zhang, Xiaolan ^d   Wang, Li ^d   Rogov, Peter ^d   Mikkelsen, Tarjei S ^d   Kellis, Manolis ^d,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Engineering IV   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CHEMICAL ACTIVATION; CHROMOSOMES; GENE EXPRESSION;

COMPUTATIONAL APPROACH; HIGH RESOLUTION ANALYSIS; HIGH-RESOLUTION MAPPING; MASSIVELY PARALLELS; PROBABILISTIC GRAPHICAL MODELS; REGULATORY FUNCTIONS; REGULATORY REGIONS; REPORTER-GENE EXPRESSION;

NUCLEOTIDES;

DEOXYRIBONUCLEASE; NUCLEOTIDE;

ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA SYNTHESIS; EMBRYO; ENHANCER REGION; EPIGENETICS; GENE EXPRESSION; GENE MAPPING; GENETIC CONSERVATION; GENOME; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; K562 CELL LINE; LONG TERMINAL REPEAT; PRIORITY JOURNAL; PROMOTER REGION; RNA INTERFERENCE; SCALE UP; UMBILICAL VEIN ENDOTHELIAL CELL; CHROMOSOMAL MAPPING; CONSERVED SEQUENCE; EPIGENETIC REPRESSION; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; PROCEDURES; REGULATORY SEQUENCE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

CHROMOSOME MAPPING; CONSERVED SEQUENCE; EPIGENETIC REPRESSION; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; NUCLEOTIDES; REGULATORY SEQUENCES, NUCLEIC ACID; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84994802525     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3678     Document Type: Article

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