Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity

Journal of Clinical Investigation

Volumn 126, Issue 11, 2016, Pages 4219-4236

  Massaad, Michel J ^a   Zhou, Jia ^b   Tsuchimoto, Daisuke ^c   Chou, Janet ^a   Jabara, Haifa ^a   Janssen, Erin ^a   Glauzy, Salomé ^d   Olson, Brennan G ^d   Morbach, Henner ^d   Ohsumi, Toshiro K ^e   Schmitz, Klaus ^a   Kyriacos, Markianos ^a   Kane, Jennifer ^a   Torisu, Kumiko ^c   Nakabeppu, Yusaku ^c   Notarangelo, Luigi D ^a   Chouery, Eliane ^f   Megarbane, Andre ^f   Kang, Peter B ^a   Al Idrissi, Eman ^g   Aldhekri, Hasan ^h   Meffre, Eric ^d   Mizui, Masayuki ⁱ   Tsokos, George C ⁱ   Manis, John P ^a   Al Herz, Waleed ^j,k   Wallace, Susan S ^b   Geha, Raif S ^a   more..

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c KYUSHU UNIVERSITY   (Japan)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f SAINT JOSEPH UNIVERSITY   (Lebanon)

^g KING FAHAD MEDICAL CITY   (Saudi Arabia)

^h KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j KUWAIT UNIVERSITY   (Kuwait)

^k AL SABAH HOSPITAL   (Kuwait)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN; PROTEIN LRBA; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE; FLJ10858 PROTEIN, HUMAN; GLYCOSIDASE; LRBA PROTEIN, HUMAN; LRBA PROTEIN, MOUSE; NEIL3 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELL DEATH; CHILD; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVITY; FEMALE; GENE; GERMINAL CENTER; HOMOZYGOSITY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN DEFICIENCY; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE FUNCTION; MALE; MISSENSE MUTATION; MOUSE; NEIL3 GENE; NEPHRITIS; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENT INFECTION; SCHOOL CHILD; SPLENIC B CELL; SPLENIC T CELL; YOUNG ADULT; ANIMAL; AUTOIMMUNE DISEASE; DEFICIENCY; DRUG EFFECTS; GENETIC PREDISPOSITION; GENETICS; HELA CELL LINE; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; B-LYMPHOCYTES; ENDODEOXYRIBONUCLEASES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HELA CELLS; HUMANS; MALE; MICE; MICE, KNOCKOUT; N-GLYCOSYL HYDROLASES; POLY I-C; T-LYMPHOCYTES;

EID: 84994626504     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI85647     Document Type: Article

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