Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 311, Issue 5, 2016, Pages L881-L892

  Pouwels, Simon D ^a   Hesse, Laura ^a   Faiz, Alen ^a   Lubbers, Jaap ^a   Bodha, Priya K ^a   ten Hacken, Nick H T ^a   van Oosterhout, Antoon J M ^a   Nawijn, Martijn C ^a   Heijink, Irene H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Airway inflammation; COPD; DAMP; LL 37; Mitochondrial damps

Indexed keywords

CALGRANULIN B; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CIGARETTE SMOKE; DAMAGE ASSOCIATED MOLECULAR PATTERN; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 2; GALECTIN 3; HIGH MOBILITY GROUP B1 PROTEIN; HYALURON SYNTHASE 2; IMMUNOLOGIC FACTOR; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; ALARMIN; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE;

ADULT; AIRWAY EPITHELIAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS BIOPSY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE PREDISPOSITION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; MALE; MIDDLE AGED; MITOCHONDRION; MOUSE; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFLAMMATION; SMOKING; ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; CELL DEATH; COMPLICATION; DBA MOUSE; EPITHELIUM; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; INFLAMMATION; INTRANASAL DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; PNEUMONIA;

ADMINISTRATION, INTRANASAL; ADULT; ALARMINS; ANIMALS; CATHELICIDINS; CELL DEATH; EPITHELIAL CELLS; EPITHELIUM; GALECTIN 3; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION; INTERLEUKIN-8; MICE, INBRED C57BL; MICE, INBRED DBA; MITOCHONDRIA; NEUTROPHILS; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING;

EID: 84994571977     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00135.2016     Document Type: Article

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