Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: From specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study

BMJ Open

Volumn 3, Issue 2, 2013, Pages

  Lo Tam Loi, Adéle T ^a   Hoonhorst, Susan J M ^b   Franciosi, Lorenza ^b,c   Bischoff, Rainer ^b,c   Hoffmann, Roland F ^b   Heijink, Irene ^b   Van Oosterhout, Antoon J M ^b   Boezen, H Marike ^b   Timens, Wim ^b   Postma, Dirkje S ^b   Lammers, Jan Willem ^a   Koenderman, Leo ^a   Ten Hacken, Nick H T ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD11B ANTIGEN; CD14 ANTIGEN; CD18 ANTIGEN; CD63 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 1BETA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD SAMPLING; BODY COMPOSITION; BRONCHUS BIOPSY; CHRONIC INFLAMMATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL PROTOCOL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; DISEASE SEVERITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; LUNG FUNCTION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PREVALENCE; PROTEIN EXPRESSION; PROTEOMICS; QUESTIONNAIRE; SMOKING; SPUTUM; URINALYSIS; WALKING;

EID: 84875130751     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2012-002178     Document Type: Article

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