메뉴 건너뛰기




Volumn 11, Issue 11, 2016, Pages

Intracellular iron chelation modulates the macrophage iron phenotype with consequences on tumor progression

Author keywords

[No Author keywords available]

Indexed keywords

IRON; IRON CHELATING AGENT; MESSENGER RNA;

EID: 84994386042     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0166164     Document Type: Article
Times cited : (72)

References (56)
  • 1
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • PMID: 19029990
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008; 8(12):958-69. doi: 10.1038/nri2448 PMID: 19029990
    • (2008) Nat Rev Immunol , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 2
    • 84901393470 scopus 로고    scopus 로고
    • The role of macrophage polarization in infectious and inflammatory diseases
    • PMID: 24625576
    • Labonte AC, Tosello-Trampont AC, Hahn YS. The role of macrophage polarization in infectious and inflammatory diseases. Mol Cells. 2014; 37(4):275-85. doi: 10.14348/molcells.2014.2374 PMID: 24625576
    • (2014) Mol Cells , vol.37 , Issue.4 , pp. 275-285
    • Labonte, A.C.1    Tosello-Trampont, A.C.2    Hahn, Y.S.3
  • 3
    • 84860381134 scopus 로고    scopus 로고
    • Infusion of IL-10-expressing cells protects against renal ischemia through induction of lipocalin-2
    • PMID: 22278021
    • Jung M, Sola A, Hughes J, Kluth DC, Vinuesa E, Vinas JL, et al. Infusion of IL-10-expressing cells protects against renal ischemia through induction of lipocalin-2. Kidney Int. 2012; 81(10):969-82. doi: 10. 1038/ki.2011.446 PMID: 22278021
    • (2012) Kidney Int , vol.81 , Issue.10 , pp. 969-982
    • Jung, M.1    Sola, A.2    Hughes, J.3    Kluth, D.C.4    Vinuesa, E.5    Vinas, J.L.6
  • 4
    • 81355151367 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate signalling induces the production of Lcn-2 by macrophages to promote kidney regeneration
    • PMID: 22025214
    • Sola A, Weigert A, Jung M, Vinuesa E, Brecht K, Weis N, et al. Sphingosine-1-phosphate signalling induces the production of Lcn-2 by macrophages to promote kidney regeneration. J Pathol. 2011; 225 (4):597-608. doi: 10.1002/path.2982 PMID: 22025214
    • (2011) J Pathol , vol.225 , Issue.4 , pp. 597-608
    • Sola, A.1    Weigert, A.2    Jung, M.3    Vinuesa, E.4    Brecht, K.5    Weis, N.6
  • 5
    • 84959387195 scopus 로고    scopus 로고
    • Macrophage-derived Lipocalin-2 contributes to ischemic resistance mechanisms by protecting from renal injury
    • PMID: 26911537
    • Jung M, Brune B, Hotter G, Sola A. Macrophage-derived Lipocalin-2 contributes to ischemic resistance mechanisms by protecting from renal injury. Sci Rep. 2016; 6:21950. doi: 10.1038/srep21950 PMID: 26911537
    • (2016) Sci Rep. , vol.6 , pp. 21950
    • Jung, M.1    Brune, B.2    Hotter, G.3    Sola, A.4
  • 6
    • 77749260592 scopus 로고    scopus 로고
    • Differential regulation of iron homeostasis during human macrophage polarized activation
    • PMID: 20039303
    • Recalcati S, Locati M, Marini A, Santambrogio P, Zaninotto F, De Pizzol M, et al. Differential regulation of iron homeostasis during human macrophage polarized activation. Eur J Immunol. 2010; 40(3):824-35. doi: 10.1002/eji.200939889 PMID: 20039303
    • (2010) Eur J Immunol , vol.40 , Issue.3 , pp. 824-835
    • Recalcati, S.1    Locati, M.2    Marini, A.3    Santambrogio, P.4    Zaninotto, F.5    De Pizzol, M.6
  • 7
    • 79957723868 scopus 로고    scopus 로고
    • Iron trafficking and metabolism in macrophages: Contribution to the polarized phenotype
    • PMID: 21514223
    • Cairo G, Recalcati S, Mantovani A, Locati M. Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype. Trends Immunol. 2011; 32(6):241-7. doi: 10.1016/j.it.2011.03.007 PMID: 21514223
    • (2011) Trends Immunol , vol.32 , Issue.6 , pp. 241-247
    • Cairo, G.1    Recalcati, S.2    Mantovani, A.3    Locati, M.4
  • 8
    • 78449290415 scopus 로고    scopus 로고
    • The struggle for iron-a metal at the host-pathogen interface
    • PMID: 20964797
    • Nairz M, Schroll A, Sonnweber T, Weiss G. The struggle for iron-a metal at the host-pathogen interface. Cell Microbiol. 2010; 12(12):1691-702. doi: 10.1111/j.1462-5822.2010.01529.x PMID: 20964797
    • (2010) Cell Microbiol , vol.12 , Issue.12 , pp. 1691-1702
    • Nairz, M.1    Schroll, A.2    Sonnweber, T.3    Weiss, G.4
  • 9
    • 14544294358 scopus 로고    scopus 로고
    • Modification of iron regulation by the inflammatory response
    • PMID: 15737884
    • Weiss G. Modification of iron regulation by the inflammatory response. Best Pract Res Clin Haematol. 2005; 18(2):183-201. doi: 10.1016/j.beha.2004.09.001 PMID: 15737884
    • (2005) Best Pract Res Clin Haematol , vol.18 , Issue.2 , pp. 183-201
    • Weiss, G.1
  • 10
    • 84951566859 scopus 로고    scopus 로고
    • Lipocalin-2 ensures host defense against Salmonella Typhimurium by controlling macrophage iron homeostasis and immune response
    • PMID: 26332507
    • Nairz M, Schroll A, Haschka D, Dichtl S, Sonnweber T, Theurl I, et al. Lipocalin-2 ensures host defense against Salmonella Typhimurium by controlling macrophage iron homeostasis and immune response. Eur J Immunol. 2015; 45(11):3073-86. doi: 10.1002/eji.201545569 PMID: 26332507
    • (2015) Eur J Immunol , vol.45 , Issue.11 , pp. 3073-3086
    • Nairz, M.1    Schroll, A.2    Haschka, D.3    Dichtl, S.4    Sonnweber, T.5    Theurl, I.6
  • 11
    • 84874284249 scopus 로고    scopus 로고
    • Systemic and cellular consequences of macrophage control of iron metabolism
    • PMID: 23375134
    • Recalcati S, Locati M, Cairo G. Systemic and cellular consequences of macrophage control of iron metabolism. Semin Immunol. 2012; 24(6):393-8. doi: 10.1016/j.smim.2013.01.001 PMID: 23375134
    • (2012) Semin Immunol , vol.24 , Issue.6 , pp. 393-398
    • Recalcati, S.1    Locati, M.2    Cairo, G.3
  • 12
    • 84884755261 scopus 로고    scopus 로고
    • High-infiltration of tumor-associated macrophages predicts unfavorable clinical outcome for node-negative breast cancer
    • PMID: 24098773
    • Zhang Y, Cheng S, Zhang M, Zhen L, Pang D, Zhang Q, et al. High-infiltration of tumor-associated macrophages predicts unfavorable clinical outcome for node-negative breast cancer. PLoS One. 2013; 8(9):e76147. doi: 10.1371/journal.pone.0076147 PMID: 24098773
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e76147
    • Zhang, Y.1    Cheng, S.2    Zhang, M.3    Zhen, L.4    Pang, D.5    Zhang, Q.6
  • 13
    • 67349137868 scopus 로고    scopus 로고
    • Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents
    • PMID: 18485918
    • Richardson DR, Kalinowski DS, Lau S, Jansson PJ, Lovejoy DB. Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents. Biochim Biophys Acta. 2009; 1790 (7):702-17. doi: 10.1016/j.bbagen.2008.04.003 PMID: 18485918
    • (2009) Biochim Biophys Acta , vol.1790 , Issue.7 , pp. 702-717
    • Richardson, D.R.1    Kalinowski, D.S.2    Lau, S.3    Jansson, P.J.4    Lovejoy, D.B.5
  • 14
    • 0036731351 scopus 로고    scopus 로고
    • Anemia in cancer patients: Significance, epidemiology, and current therapy
    • PMID: 12380951
    • Tchekmedyian NS. Anemia in cancer patients: significance, epidemiology, and current therapy. Oncology. 2002; 16(9 Suppl 10):17-24. PMID: 12380951
    • (2002) Oncology , vol.16 , Issue.9 , pp. 17-24
    • Tchekmedyian, N.S.1
  • 15
    • 74849109475 scopus 로고    scopus 로고
    • Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen
    • PMID: 19238537
    • Habashy HO, Powe DG, Staka CM, Rakha EA, Ball G, Green AR, et al. Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast Cancer Res Treat. 2010; 119(2):283-93. doi: 10.1007/s10549-009-0345-x PMID: 19238537
    • (2010) Breast Cancer Res Treat , vol.119 , Issue.2 , pp. 283-293
    • Habashy, H.O.1    Powe, D.G.2    Staka, C.M.3    Rakha, E.A.4    Ball, G.5    Green, A.R.6
  • 16
    • 0021329517 scopus 로고
    • Distribution of ferritin, transferrin and lactoferrin in breast carcinoma tissue
    • PMID: 6323544
    • Rossiello R, Carriero MV, Giordano GG. Distribution of ferritin, transferrin and lactoferrin in breast carcinoma tissue. J Clin Pathol. 1984; 37(1):51-5. PMID: 6323544
    • (1984) J Clin Pathol , vol.37 , Issue.1 , pp. 51-55
    • Rossiello, R.1    Carriero, M.V.2    Giordano, G.G.3
  • 17
    • 84892915910 scopus 로고    scopus 로고
    • IRP2 regulates breast tumor growth
    • PMID: 24285726
    • Wang W, Deng Z, Hatcher H, Miller LD, Di X, Tesfay L, et al. IRP2 regulates breast tumor growth. Cancer Res. 2014; 74(2):497-507. doi: 10.1158/0008-5472.CAN-13-1224 PMID: 24285726
    • (2014) Cancer Res , vol.74 , Issue.2 , pp. 497-507
    • Wang, W.1    Deng, Z.2    Hatcher, H.3    Miller, L.D.4    Di, X.5    Tesfay, L.6
  • 18
    • 77951037271 scopus 로고    scopus 로고
    • Manipulation of iron transporter genes results in the suppression of human and mouse mammary adenocarcinomas
    • PMID: 20392994
    • Jiang XP, Elliott RL, Head JF. Manipulation of iron transporter genes results in the suppression of human and mouse mammary adenocarcinomas. Anticancer Res. 2010; 30(3):759-65. PMID: 20392994
    • (2010) Anticancer Res , vol.30 , Issue.3 , pp. 759-765
    • Jiang, X.P.1    Elliott, R.L.2    Head, J.F.3
  • 19
    • 84876009407 scopus 로고    scopus 로고
    • Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents
    • PMID: 23483119
    • Pogribny IP, Tryndyak VP, Pogribna M, Shpyleva S, Surratt G, Gamboa da Costa G, et al. Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents. Int J Oncol. 2013; 42(5):1822-32. doi: 10.3892/ijo.2013.1855 PMID: 23483119
    • (2013) Int J Oncol , vol.42 , Issue.5 , pp. 1822-1832
    • Pogribny, I.P.1    Tryndyak, V.P.2    Pogribna, M.3    Shpyleva, S.4    Surratt, G.5    Gamboa da Costa, G.6
  • 20
    • 84855758079 scopus 로고    scopus 로고
    • Modulation of Wnt/beta-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer
    • PMID: 21666721
    • Coombs GS, Schmitt AA, Canning CA, Alok A, Low IC, Banerjee N, et al. Modulation of Wnt/beta-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer. Oncogene. 2012; 31(2):213-25. doi: 10.1038/onc.2011.228 PMID: 21666721
    • (2012) Oncogene , vol.31 , Issue.2 , pp. 213-225
    • Coombs, G.S.1    Schmitt, A.A.2    Canning, C.A.3    Alok, A.4    Low, I.C.5    Banerjee, N.6
  • 21
    • 84879229020 scopus 로고    scopus 로고
    • A link between premenopausal iron deficiency and breast cancer malignancy
    • PMID: 23800380
    • Jian J, Yang Q, Shao Y, Axelrod D, Smith J, Singh B, et al. A link between premenopausal iron deficiency and breast cancer malignancy. BMC Cancer. 2013; 13:307. doi: 10.1186/1471-2407-13-307 PMID: 23800380
    • (2013) BMC Cancer , vol.13 , pp. 307
    • Jian, J.1    Yang, Q.2    Shao, Y.3    Axelrod, D.4    Smith, J.5    Singh, B.6
  • 22
    • 35349008009 scopus 로고    scopus 로고
    • Iron accumulation in mammary tumor suggests a tug of war between tumor and host for the microelement
    • PMID: 17970045
    • Freitas I, Boncompagni E, Vaccarone R, Fenoglio C, Barni S, Baronzio GF. Iron accumulation in mammary tumor suggests a tug of war between tumor and host for the microelement. Anticancer Res. 2007; 27(5A):3059-65. PMID: 17970045
    • (2007) Anticancer Res , vol.27 , Issue.5 A , pp. 3059-3065
    • Freitas, I.1    Boncompagni, E.2    Vaccarone, R.3    Fenoglio, C.4    Barni, S.5    Baronzio, G.F.6
  • 23
    • 77955607931 scopus 로고    scopus 로고
    • Ferroportin and iron regulation in breast cancer progression and prognosis
    • PMID: 20686179
    • Pinnix ZK, Miller LD, Wang W, D'Agostino R Jr, Kute T, Willingham MC, et al. Ferroportin and iron regulation in breast cancer progression and prognosis. Sci Transl Med. 2010; 2(43):43ra56. doi: 10.1126/ scisignal.3001127 PMID: 20686179
    • (2010) Sci Transl Med , vol.2 , Issue.43 , pp. 43ra56
    • Pinnix, Z.K.1    Miller, L.D.2    Wang, W.3    D'Agostino, R.4    Kute, T.5    Willingham, M.C.6
  • 24
    • 29844457587 scopus 로고    scopus 로고
    • The evolution of iron chelators for the treatment of iron overload disease and cancer
    • PMID: 16382108
    • Kalinowski DS, Richardson DR. The evolution of iron chelators for the treatment of iron overload disease and cancer. Pharmacol Rev. 2005; 57(4):547-83. doi: 10.1124/pr.57.4.2 PMID: 16382108
    • (2005) Pharmacol Rev , vol.57 , Issue.4 , pp. 547-583
    • Kalinowski, D.S.1    Richardson, D.R.2
  • 25
    • 77953412928 scopus 로고    scopus 로고
    • Synthetic and natural iron chelators: Therapeutic potential and clinical use
    • PMID: 21425984
    • Hatcher HC, Singh RN, Torti FM, Torti SV. Synthetic and natural iron chelators: therapeutic potential and clinical use. Future Med Chem. 2009; 1(9):1643-70. doi: 10.4155/fmc.09.121 PMID: 21425984
    • (2009) Future Med Chem , vol.1 , Issue.9 , pp. 1643-1670
    • Hatcher, H.C.1    Singh, R.N.2    Torti, F.M.3    Torti, S.V.4
  • 26
    • 0025726827 scopus 로고
    • Failure to alter the course of acute myelogenous leukemia in the rat with subcutaneous deferoxamine
    • PMID: 2046391
    • Blatt J, Boegel F, Hedlund BE, Arena VC, Shadduck RK. Failure to alter the course of acute myelogenous leukemia in the rat with subcutaneous deferoxamine. Leuk Res. 1991; 15(5):391-4. PMID: 2046391
    • (1991) Leuk Res , vol.15 , Issue.5 , pp. 391-394
    • Blatt, J.1    Boegel, F.2    Hedlund, B.E.3    Arena, V.C.4    Shadduck, R.K.5
  • 27
    • 84907618316 scopus 로고    scopus 로고
    • Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators
    • PMID: 25100578
    • Akam EA, Chang TM, Astashkin AV, Tomat E. Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators. Metallomics. 2014; 6(10):1905-12. doi: 10.1039/c4mt00153b PMID: 25100578
    • (2014) Metallomics , vol.6 , Issue.10 , pp. 1905-1912
    • Akam, E.A.1    Chang, T.M.2    Astashkin, A.V.3    Tomat, E.4
  • 28
    • 84878038782 scopus 로고    scopus 로고
    • Disulfide/thiol switches in thiosemicarbazone ligands for redox-directed iron chelation
    • PMID: 23591852
    • Chang TM, Tomat E. Disulfide/thiol switches in thiosemicarbazone ligands for redox-directed iron chelation. Dalton Trans. 2013; 42(22):7846-9. doi: 10.1039/c3dt50824b PMID: 23591852
    • (2013) Dalton Trans , vol.42 , Issue.22 , pp. 7846-7849
    • Chang, T.M.1    Tomat, E.2
  • 29
    • 0026520603 scopus 로고
    • PCNA and Ki67 expression in breast carcinoma: Correlations with clinical and biological variables
    • PMID: 1350788
    • Leonardi E, Girlando S, Serio G, Mauri FA, Perrone G, Scampini S, et al. PCNA and Ki67 expression in breast carcinoma: correlations with clinical and biological variables. J Clin Pathol. 1992; 45(5):416-9. PMID: 1350788
    • (1992) J Clin Pathol , vol.45 , Issue.5 , pp. 416-419
    • Leonardi, E.1    Girlando, S.2    Serio, G.3    Mauri, F.A.4    Perrone, G.5    Scampini, S.6
  • 30
    • 0032432051 scopus 로고    scopus 로고
    • The expression of the proliferating antigen Ki67, PCNA and products of suppressor gene p53 in primary invasive ductal breast carcinoma
    • PMID: 10089075
    • Niewiadomska H, Jeziorski A, Olborski B. The expression of the proliferating antigen Ki67, PCNA and products of suppressor gene p53 in primary invasive ductal breast carcinoma. J Exp Clin Cancer Res. 1998; 17(4):503-10. PMID: 10089075
    • (1998) J Exp Clin Cancer Res , vol.17 , Issue.4 , pp. 503-510
    • Niewiadomska, H.1    Jeziorski, A.2    Olborski, B.3
  • 31
    • 84888131588 scopus 로고    scopus 로고
    • Liver X receptor activation stimulates iron export in human alternative macrophages
    • PMID: 24036496
    • Bories G, Colin S, Vanhoutte J, Derudas B, Copin C, Fanchon M, et al. Liver X receptor activation stimulates iron export in human alternative macrophages. Circ Res. 2013; 113(11):1196-205. doi: 10. 1161/CIRCRESAHA.113.301656 PMID: 24036496
    • (2013) Circ Res , vol.113 , Issue.11 , pp. 1196-1205
    • Bories, G.1    Colin, S.2    Vanhoutte, J.3    Derudas, B.4    Copin, C.5    Fanchon, M.6
  • 32
    • 77954271890 scopus 로고    scopus 로고
    • Iron regulatory proteins: From molecular mechanisms to drug development
    • PMID: 20214491
    • Recalcati S, Minotti G, Cairo G. Iron regulatory proteins: from molecular mechanisms to drug development. Antioxid Redox Signal. 2010; 13(10):1593-616. doi: 10.1089/ars.2009.2983 PMID: 20214491
    • (2010) Antioxid Redox Signal , vol.13 , Issue.10 , pp. 1593-1616
    • Recalcati, S.1    Minotti, G.2    Cairo, G.3
  • 33
    • 0346216146 scopus 로고    scopus 로고
    • Effects of hypoxia and intracellular iron chelation on hypoxiainducible factor-1alpha and -1beta in the rat carotid body and glomus cells
    • PMID: 14600837
    • Baby SM, Roy A, Mokashi AM, Lahiri S. Effects of hypoxia and intracellular iron chelation on hypoxiainducible factor-1alpha and -1beta in the rat carotid body and glomus cells. Histochem Cell Biol. 2003; 120(5):343-52. doi: 10.1007/s00418-003-0588-2 PMID: 14600837
    • (2003) Histochem Cell Biol , vol.120 , Issue.5 , pp. 343-352
    • Baby, S.M.1    Roy, A.2    Mokashi, A.M.3    Lahiri, S.4
  • 34
    • 33947581110 scopus 로고    scopus 로고
    • Hypoxia inducible factor prolyl 4-hydroxylase enzymes: Center stage in the battle against hypoxia, metabolic compromise and oxidative stress
    • PMID: 17342411
    • Siddiq A, Aminova LR, Ratan RR. Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. Neurochem Res. 2007; 32 (4-5):931-46. doi: 10.1007/s11064-006-9268-7 PMID: 17342411
    • (2007) Neurochem Res , vol.32 , Issue.4-5 , pp. 931-946
    • Siddiq, A.1    Aminova, L.R.2    Ratan, R.R.3
  • 35
    • 84880585829 scopus 로고    scopus 로고
    • Cellular iron metabolism in prognosis and therapy of breast cancer
    • PMID: 23879588
    • Torti SV, Torti FM. Cellular iron metabolism in prognosis and therapy of breast cancer. Crit Rev Oncog. 2013; 18(5):435-48. PMID: 23879588
    • (2013) Crit Rev Oncog , vol.18 , Issue.5 , pp. 435-448
    • Torti, S.V.1    Torti, F.M.2
  • 36
    • 84876854791 scopus 로고    scopus 로고
    • Iron and cancer: More ore to be mined
    • PMID: 23594855
    • Torti SV, Torti FM. Iron and cancer: more ore to be mined. Nat Rev Cancer. 2013; 13(5):342-55. doi: 10.1038/nrc3495 PMID: 23594855
    • (2013) Nat Rev Cancer , vol.13 , Issue.5 , pp. 342-355
    • Torti, S.V.1    Torti, F.M.2
  • 37
    • 80155131215 scopus 로고    scopus 로고
    • An iron regulatory gene signature predicts outcome in breast cancer
    • PMID: 21875943
    • Miller LD, Coffman LG, Chou JW, Black MA, Bergh J, D'Agostino R Jr, et al. An iron regulatory gene signature predicts outcome in breast cancer. Cancer Res. 2011; 71(21):6728-37. doi: 10.1158/0008-5472.CAN-11-1870 PMID: 21875943
    • (2011) Cancer Res , vol.71 , Issue.21 , pp. 6728-6737
    • Miller, L.D.1    Coffman, L.G.2    Chou, J.W.3    Black, M.A.4    Bergh, J.5    D'Agostino, R.6
  • 38
    • 78149234350 scopus 로고    scopus 로고
    • Control of iron homeostasis as a key component of macrophage polarization
    • PMID: 21037324
    • Gaetano C, Massimo L, Alberto M. Control of iron homeostasis as a key component of macrophage polarization. Haematologica. 2010; 95(11):1801-3. doi: 10.3324/haematol.2010.030239 PMID: 21037324
    • (2010) Haematologica , vol.95 , Issue.11 , pp. 1801-1803
    • Gaetano, C.1    Massimo, L.2    Alberto, M.3
  • 39
    • 84861598906 scopus 로고    scopus 로고
    • Validation of tumor-associated macrophage ferritin light chain as a prognostic biomarker in node-negative breast cancer tumors: A multicentric 2004 national PHRC study
    • PMID: 21898387
    • Jezequel P, Campion L, Spyratos F, Loussouarn D, Campone M, Guerin-Charbonnel C, et al. Validation of tumor-associated macrophage ferritin light chain as a prognostic biomarker in node-negative breast cancer tumors: A multicentric 2004 national PHRC study. Int J Cancer. 2012; 131(2):426-37. doi: 10.1002/ijc.26397 PMID: 21898387
    • (2012) Int J Cancer , vol.131 , Issue.2 , pp. 426-437
    • Jezequel, P.1    Campion, L.2    Spyratos, F.3    Loussouarn, D.4    Campone, M.5    Guerin-Charbonnel, C.6
  • 40
    • 34548286520 scopus 로고    scopus 로고
    • Tuning cell cycle regulation with an iron key
    • PMID: 17721086
    • Yu Y, Kovacevic Z, Richardson DR. Tuning cell cycle regulation with an iron key. Cell Cycle. 2007; 6 (16):1982-94. doi: 10.4161/cc.6.16.4603 PMID: 17721086
    • (2007) Cell Cycle , vol.6 , Issue.16 , pp. 1982-1994
    • Yu, Y.1    Kovacevic, Z.2    Richardson, D.R.3
  • 41
    • 84861212961 scopus 로고    scopus 로고
    • The iron chelators Dp44mT and DFO inhibit TGF-beta-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1)
    • PMID: 22453918
    • Chen Z, Zhang D, Yue F, Zheng M, Kovacevic Z, Richardson DR. The iron chelators Dp44mT and DFO inhibit TGF-beta-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1). J Biol Chem. 2012; 287(21):17016-28. doi: 10.1074/jbc.M112. 350470 PMID: 22453918
    • (2012) J Biol Chem , vol.287 , Issue.21 , pp. 17016-17028
    • Chen, Z.1    Zhang, D.2    Yue, F.3    Zheng, M.4    Kovacevic, Z.5    Richardson, D.R.6
  • 42
    • 84926372869 scopus 로고    scopus 로고
    • Macrophage iron homeostasis and polarization in the context of cancer
    • PMID: 25260218
    • Jung M, Mertens C, Brune B. Macrophage iron homeostasis and polarization in the context of cancer. Immunobiology. 2015; 220(2):295-304. doi: 10.1016/j.imbio.2014.09.011 PMID: 25260218
    • (2015) Immunobiology , vol.220 , Issue.2 , pp. 295-304
    • Jung, M.1    Mertens, C.2    Brune, B.3
  • 43
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • PMID: 16423985
    • Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006; 66(2):605-12. doi: 10.1158/0008-5472.CAN-05-4005 PMID: 16423985
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 44
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • PMID: 16520032
    • Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer. 2006; 42(6):717-27. doi: 10.1016/j.ejca.2006.01.003 PMID: 16520032
    • (2006) Eur J Cancer , vol.42 , Issue.6 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 45
    • 33845524204 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in tumor progression and invasion
    • PMID: 16967326
    • Mantovani A, Schioppa T, Porta C, Allavena P, Sica A. Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev. 2006; 25(3):315-22. doi: 10.1007/s10555-006-9001-7 PMID: 16967326
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.3 , pp. 315-322
    • Mantovani, A.1    Schioppa, T.2    Porta, C.3    Allavena, P.4    Sica, A.5
  • 46
    • 78149250305 scopus 로고    scopus 로고
    • Polarization dictates iron handling by inflammatory and alternatively activated macrophages
    • PMID: 20511666
    • Corna G, Campana L, Pignatti E, Castiglioni A, Tagliafico E, Bosurgi L, et al. Polarization dictates iron handling by inflammatory and alternatively activated macrophages. Haematologica. 2010; 95 (11):1814-22. doi: 10.3324/haematol.2010.023879 PMID: 20511666
    • (2010) Haematologica , vol.95 , Issue.11 , pp. 1814-1822
    • Corna, G.1    Campana, L.2    Pignatti, E.3    Castiglioni, A.4    Tagliafico, E.5    Bosurgi, L.6
  • 47
    • 0037926880 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of iron transport in human monocytic cells
    • PMID: 12522003
    • Ludwiczek S, Aigner E, Theurl I, Weiss G. Cytokine-mediated regulation of iron transport in human monocytic cells. Blood. 2003; 101(10):4148-54. doi: 10.1182/blood-2002-08-2459 PMID: 12522003
    • (2003) Blood , vol.101 , Issue.10 , pp. 4148-4154
    • Ludwiczek, S.1    Aigner, E.2    Theurl, I.3    Weiss, G.4
  • 48
    • 84879571563 scopus 로고    scopus 로고
    • Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection
    • PMID: 23630227
    • Nairz M, Schleicher U, Schroll A, Sonnweber T, Theurl I, Ludwiczek S, et al. Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J Exp Med. 2013; 210(5):855-73. doi: 10.1084/jem.20121946 PMID: 23630227
    • (2013) J Exp Med , vol.210 , Issue.5 , pp. 855-873
    • Nairz, M.1    Schleicher, U.2    Schroll, A.3    Sonnweber, T.4    Theurl, I.5    Ludwiczek, S.6
  • 49
    • 50549086197 scopus 로고    scopus 로고
    • Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium
    • PMID: 18581323
    • Nairz M, Fritsche G, Brunner P, Talasz H, Hantke K, Weiss G. Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium. Eur J Immunol. 2008; 38(7):1923-36. doi: 10. 1002/eji.200738056 PMID: 18581323
    • (2008) Eur J Immunol , vol.38 , Issue.7 , pp. 1923-1936
    • Nairz, M.1    Fritsche, G.2    Brunner, P.3    Talasz, H.4    Hantke, K.5    Weiss, G.6
  • 50
    • 50849090319 scopus 로고    scopus 로고
    • Macrophages define the invasive microenvironment in breast cancer
    • PMID: 18467655
    • Pollard JW. Macrophages define the invasive microenvironment in breast cancer. J Leukoc Biol. 2008; 84(3):623-30. doi: 10.1189/jlb.1107762 PMID: 18467655
    • (2008) J Leukoc Biol , vol.84 , Issue.3 , pp. 623-630
    • Pollard, J.W.1
  • 51
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • PMID: 17705880
    • DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res. 2007; 9(4):212. doi: 10.1186/bcr1746 PMID: 17705880
    • (2007) Breast Cancer Res , vol.9 , Issue.4 , pp. 212
    • DeNardo, D.G.1    Coussens, L.M.2
  • 53
    • 84879334969 scopus 로고    scopus 로고
    • Ferritin stimulates breast cancer cells through an iron-independent mechanism and is localized within tumor-associated macrophages
    • PMID: 23306463
    • Alkhateeb AA, Han B, Connor JR. Ferritin stimulates breast cancer cells through an iron-independent mechanism and is localized within tumor-associated macrophages. Breast Cancer Res Treat. 2013; 137(3):733-44. doi: 10.1007/s10549-012-2405-x PMID: 23306463
    • (2013) Breast Cancer Res Treat , vol.137 , Issue.3 , pp. 733-744
    • Alkhateeb, A.A.1    Han, B.2    Connor, J.R.3
  • 56
    • 84866531103 scopus 로고    scopus 로고
    • Iron levels in polarized macrophages: Regulation of immunity and autoimmunity
    • Recalcati S, Locati M, Gammella E, Invernizzi P, Cairo G. Iron levels in polarized macrophages: regulation of immunity and autoimmunity. Autoimmun Rev. 2012; 11(12):883-9. doi: 10.1016/j.autrev. 2012.03.003 PMID: 22449938
    • (2012) Autoimmun Rev , vol.11 , Issue.12 , pp. 883-889
    • Recalcati, S.1    Locati, M.2    Gammella, E.3    Invernizzi, P.4    Cairo, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.