Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study

PLoS Medicine

Volumn 13, Issue 10, 2016, Pages

  Casali, Nicola ^a,b   Broda, Agnieszka ^a   Harris, Simon R ^c   Parkhill, Julian ^c   Brown, Timothy ^d   Drobniewski, Francis ^a,d,e  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

^e BARTS HEALTH NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ISONIAZID; RIFAMPICIN; BACTERIAL DNA;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DISEASE TRANSMISSION; DRUG RESISTANT TUBERCULOSIS; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; NONHUMAN; OBSERVATIONAL STUDY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RETROSPECTIVE STUDY; RPOB GENE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM; WHOLE GENOME SEQUENCING; ADULT; BACTERIAL GENOME; CHILD; DNA SEQUENCE; ENGLAND; EPIDEMIC; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MYCOBACTERIUM TUBERCULOSIS; TRANSMISSION; TUBERCULOSIS; TUBERCULOSIS, PULMONARY; VARIABLE NUMBER OF TANDEM REPEAT;

ADULT; CHILD; DISEASE OUTBREAKS; DNA, BACTERIAL; GENOME, BACTERIAL; HUMANS; ISONIAZID; LONDON; MINISATELLITE REPEATS; MYCOBACTERIUM TUBERCULOSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA; TUBERCULOSIS; TUBERCULOSIS, PULMONARY;

EID: 84994382251     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1002137     Document Type: Article

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