Cinacalcet ameliorates aortic calcification in uremic rats via suppression of endothelial-to-mesenchymal transition

Acta Pharmacologica Sinica

Volumn 37, Issue 11, 2016, Pages 1423-1431

  Wu, Min ^a   Tang, Ri Ning ^a   Liu, Hong ^a   Pan, Ming Ming ^a   Liu, Bi Cheng ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

aortic calcification; cinacalcet; endothelial cells; endothelial to mesenchymal transition; parathyroid hormone; uremia

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALCIUM; CALVASCULIN; CD31 ANTIGEN; CINACALCET; COL2A1 PROTEIN; PHOSPHORUS; PROTEIN; PROTEOGLYCAN; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; CALCIMIMETIC AGENT; PARATHYROID HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA DISEASE; AORTIC CALCIFICATION; AORTIC ENDOTHELIAL CELL; ARTICLE; CALCIFICATION; CALCIUM BLOOD LEVEL; CARTILAGE CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; NONHUMAN; PHOSPHATE BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TREATMENT DURATION; UPREGULATION; UREMIA; ANIMAL; AORTA; BLOOD; COMPLICATION; DRUG EFFECTS; ENDOTHELIUM CELL; PATHOLOGY; VASCULAR CALCIFICATION; WISTAR RAT;

ANIMALS; AORTA; CALCIMIMETIC AGENTS; ENDOTHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; MALE; PARATHYROID HORMONE; RATS, WISTAR; UREMIA; VASCULAR CALCIFICATION;

EID: 84994302360     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2016.83     Document Type: Article

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