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Volumn 307, Issue 8, 2014, Pages F891-F900

A current understanding of vascular calcification in CKD

Author keywords

Calciprotein particles; Chronic kidney disease; MicroRNA; Vascular calcification; Vesicles

Indexed keywords

BIOLOGICAL MARKER; CALCIPROTEIN; CALCIUM; ELASTIN; MICRORNA; PHOSPHORUS; UNCLASSIFIED DRUG;

EID: 84908061325     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00163.2014     Document Type: Review
Times cited : (266)

References (127)
  • 3
    • 84863657415 scopus 로고    scopus 로고
    • Predictive value of circulating endothelial microparticles for cardiovascular mortality in end-stage renal failure: A pilot study
    • Amabile N, Guerin AP, Tedgui A, Boulanger CM, London GM. Predictive value of circulating endothelial microparticles for cardiovascular mortality in end-stage renal failure: a pilot study. Nephrol Dial Transplant 27: 1873-1880, 2012.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 1873-1880
    • Amabile, N.1    Guerin, A.P.2    Tedgui, A.3    Boulanger, C.M.4    London, G.M.5
  • 4
    • 0014141377 scopus 로고
    • Electron microscopic studies of induced cartilage development and calcification
    • Anderson HC. Electron microscopic studies of induced cartilage development and calcification. J Cell Biol 35: 81-101, 1967.
    • (1967) J Cell Biol , vol.35 , pp. 81-101
    • Anderson, H.C.1
  • 8
    • 0027474492 scopus 로고
    • Contribution of platelet microparticle formation and granule secretion to the transmembrane migration of phosphatidylserine
    • Chang CP, Zhao J, Wiedmer T, Sims PJ. Contribution of platelet microparticle formation and granule secretion to the transmembrane migration of phosphatidylserine. J Biol Chem 268: 7171-7178, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 7171-7178
    • Chang, C.P.1    Zhao, J.2    Wiedmer, T.3    Sims, P.J.4
  • 10
    • 76749098069 scopus 로고    scopus 로고
    • Verapamil inhibits calcification and matrix vesicle activity of bovine vascular smooth muscle cells
    • Chen NX, Kircelli F, O'Neill KD, Chen X, Moe SM. Verapamil inhibits calcification and matrix vesicle activity of bovine vascular smooth muscle cells. Kidney Int 77: 436-442, 2010.
    • (2010) Kidney Int , vol.77 , pp. 436-442
    • Chen, N.X.1    Kircelli, F.2    O'neill, K.D.3    Chen, X.4    Moe, S.M.5
  • 12
    • 54249105344 scopus 로고    scopus 로고
    • Annexin-mediated matrix vesicle calcification in vascular smooth muscle cells
    • Chen NX, O'Neill KD, Chen X, Moe SM. Annexin-mediated matrix vesicle calcification in vascular smooth muscle cells. J Bone Miner Res 23: 1798-1805, 2008.
    • (2008) J Bone Miner Res , vol.23 , pp. 1798-1805
    • Chen, N.X.1    O'neill, K.D.2    Chen, X.3    Moe, S.M.4
  • 18
  • 19
    • 84865593466 scopus 로고    scopus 로고
    • RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: Dependence on IL-6 and TNF-a
    • Deuell KA, Callegari A, Giachelli CM, Rosenfeld ME, Scatena M. RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-a. J Vasc Res 49: 510-521, 2012.
    • (2012) J Vasc Res , vol.49 , pp. 510-521
    • Deuell, K.A.1    Callegari, A.2    Giachelli, C.M.3    Rosenfeld, M.E.4    Scatena, M.5
  • 22
    • 78649297306 scopus 로고    scopus 로고
    • Association of fetuin-A and cardiac calcification and inflammation levels in hemodial-ysis patients
    • El-Shehaby AM, Zakaria A, El-Khatib M, Mostafa N. Association of fetuin-A and cardiac calcification and inflammation levels in hemodial-ysis patients. Scand J Clin Lab Invest 70: 575-582, 2010.
    • (2010) Scand J Clin Lab Invest , vol.70 , pp. 575-582
    • El-Shehaby, A.M.1    Zakaria, A.2    El-Khatib, M.3    Mostafa, N.4
  • 25
    • 0032494113 scopus 로고    scopus 로고
    • TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
    • Fuller K, Wong B, Fox S, Choi Y, Chambers TJ. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. J Exp Med 188: 997-1001, 1998.
    • (1998) J Exp Med , vol.188 , pp. 997-1001
    • Fuller, K.1    Wong, B.2    Fox, S.3    Choi, Y.4    Chambers, T.J.5
  • 27
    • 17644398457 scopus 로고    scopus 로고
    • Regulation of vascular calcification: Roles of phosphate and osteopontin
    • Giachelli CM, Speer MY, Li X, Rajachar RM, Yang H. Regulation of vascular calcification: roles of phosphate and osteopontin. Circ Res 96: 717-722, 2005.
    • (2005) Circ Res , vol.96 , pp. 717-722
    • Giachelli, C.M.1    Speer, M.Y.2    Li, X.3    Rajachar, R.M.4    Yang, H.5
  • 28
    • 9644276844 scopus 로고    scopus 로고
    • Vascular calcification mechanisms
    • Giachelli CM. Vascular calcification mechanisms. J Am Soc Nephrol 15: 2959-2964, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2959-2964
    • Giachelli, C.M.1
  • 29
    • 64949130692 scopus 로고    scopus 로고
    • The emerging role of phosphate in vascular calcification
    • Giachelli CM. The emerging role of phosphate in vascular calcification. Kidney Int 75: 890-897, 2009.
    • (2009) Kidney Int , vol.75 , pp. 890-897
    • Giachelli, C.M.1
  • 30
    • 33645102836 scopus 로고    scopus 로고
    • Idiopathic infantile arterial calcification: Two case reports, a review of the literature and a role for cardiac transplantation
    • Glatz AC, Pawel BR, Hsu DT, Weinberg P, Chrisant MRK. Idiopathic infantile arterial calcification: two case reports, a review of the literature and a role for cardiac transplantation. Pediatr Transplant 10: 225-233, 2006.
    • (2006) Pediatr Transplant , vol.10 , pp. 225-233
    • Glatz, A.C.1    Pawel, B.R.2    Hsu, D.T.3    Weinberg, P.4    Chrisant, R.K.5
  • 32
    • 4644323860 scopus 로고    scopus 로고
    • Vascular calcification: A stiff challenge for the nephrologist: Does preventing bone disease cause arterial disease?
    • Goldsmith D, Ritz E, Covic A. Vascular calcification: a stiff challenge for the nephrologist: does preventing bone disease cause arterial disease? Kidney Int 66: 1315-1333, 2004.
    • (2004) Kidney Int , vol.66 , pp. 1315-1333
    • Goldsmith, D.1    Ritz, E.2    Covic, A.3
  • 34
    • 84865639209 scopus 로고    scopus 로고
    • MicroRNAs that target Ca2+ transporters are involved in vascular smooth muscle cell calcification
    • Gui T, Zhou G, Sun Y, Shimokado A, Itoh S, Oikawa K, Muragaki Y. MicroRNAs that target Ca2+ transporters are involved in vascular smooth muscle cell calcification. Lab Invest 92: 1250-1259, 2012.
    • (2012) Lab Invest , vol.92 , pp. 1250-1259
    • Gui, T.1    Zhou, G.2    Sun, Y.3    Shimokado, A.4    Itoh, S.5    Oikawa, K.6    Muragaki, Y.7
  • 36
    • 0038645812 scopus 로고    scopus 로고
    • Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles
    • Heiss A, DuChesne A, Denecke B, Grotzinger J, Yamamoto K, Renne T, Jahnen-Dechent W. Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. J Biol Chem 278: 13333-13341, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 13333-13341
    • Heiss, A.1    Duchesne, A.2    Denecke, B.3    Grotzinger, J.4    Yamamoto, K.5    Renne, T.6    Jahnen-Dechent, W.7
  • 37
    • 47249089087 scopus 로고    scopus 로고
    • Hierarchical role of fetuin-A and acidic serum proteins in the formation and stabilization of calcium phosphate particles
    • Heiss A, Eckert T, Aretz A, Richtering W, van Dorp W, Schafer C, Jahnen-Dechent W. Hierarchical role of fetuin-A and acidic serum proteins in the formation and stabilization of calcium phosphate particles. J Biol Chem 283: 14815-14825, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 14815-14825
    • Heiss, A.1    Eckert, T.2    Aretz, A.3    Richtering, W.4    Van Dorp, W.5    Schafer, C.6    Jahnen-Dechent, W.7
  • 38
    • 41949085260 scopus 로고    scopus 로고
    • Structural dynamics of a colloidal protein-mineral complex bestowing on calcium phosphate a high solubility in biological fluids
    • Heiss A, Jahnen-Dechent W, Endo H, Schwahn D. Structural dynamics of a colloidal protein-mineral complex bestowing on calcium phosphate a high solubility in biological fluids. Biointerphases 2: 16-20, 2007.
    • (2007) Biointerphases , vol.2 , pp. 16-20
    • Heiss, A.1    Jahnen-Dechent, W.2    Endo, H.3    Schwahn, D.4
  • 47
    • 84860805316 scopus 로고    scopus 로고
    • Increased levels of serum parathyroid hormone and fibroblast growth factor-23 are the main factors associated with the progression of vascular calcification in long-hour hemodialysis patients
    • Jean G, Bresson E, Lorriaux C, Mayor B, Hurot JM, Deleaval P, Chazot C. Increased levels of serum parathyroid hormone and fibroblast growth factor-23 are the main factors associated with the progression of vascular calcification in long-hour hemodialysis patients. Nephron Clin Pract 120: c132-c138, 2012.
    • (2012) Nephron Clin Pract , vol.120 , pp. c138-c138
    • Jean, G.1    Bresson, E.2    Lorriaux, C.3    Mayor, B.4    Hurot, J.M.5    Deleaval, P.6    Chazot, C.7
  • 49
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
    • Ji R, Cheng Y, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res 100: 1579-1588, 2007.
    • (2007) Circ Res , vol.100 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 50
    • 33745609766 scopus 로고    scopus 로고
    • Inflammation, mineral metabolism and progressive coronary artery calcification in patients on haemodialysis
    • Jung HH, Kim SW, Han H. Inflammation, mineral metabolism and progressive coronary artery calcification in patients on haemodialysis. Nephrol Dial Transplant 21: 1915-1920, 2006.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1915-1920
    • Jung, H.H.1    Kim, S.W.2    Han, H.3
  • 51
    • 33947598333 scopus 로고    scopus 로고
    • Osteopontin upregulation and polymerization by transglutaminase 2 in calcified arteries of Matrix Gla protein-deficient mice
    • Kaartinen MT, Murshed M, Karsenty G, McKee MD. Osteopontin upregulation and polymerization by transglutaminase 2 in calcified arteries of Matrix Gla protein-deficient mice. J Histochem Cytochem 55: 375-386, 2007.
    • (2007) J Histochem Cytochem , vol.55 , pp. 375-386
    • Kaartinen, M.T.1    Murshed, M.2    Karsenty, G.3    McKee, M.D.4
  • 55
    • 77956633892 scopus 로고    scopus 로고
    • Phosphate and vascular calcification: Emerging role of the sodium-dependent phosphate co-transporter PiT-1
    • Lau WL, Festing MH, Giachelli CM. Phosphate and vascular calcification: emerging role of the sodium-dependent phosphate co-transporter PiT-1. Thromb Haemost 104: 464-470, 2010.
    • (2010) Thromb Haemost , vol.104 , pp. 464-470
    • Lau, W.L.1    Festing, M.H.2    Giachelli, C.M.3
  • 57
    • 84879292196 scopus 로고    scopus 로고
    • Vascular calcification: An age-old problem of old age
    • Leopold JA. Vascular calcification: an age-old problem of old age. Circulation 127: 2380-2382, 2013.
    • (2013) Circulation , vol.127 , pp. 2380-2382
    • Leopold, J.A.1
  • 59
    • 34250613172 scopus 로고    scopus 로고
    • Sodium-dependent phosphate cotransporters and vascular calcification
    • Li X, Giachelli CM. Sodium-dependent phosphate cotransporters and vascular calcification. Curr Opin Nephrol Hypertens 16: 325-328, 2007.
    • (2007) Curr Opin Nephrol Hypertens , vol.16 , pp. 325-328
    • Li, X.1    Giachelli, C.M.2
  • 60
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X, Yang H., Giachelli CM. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 98: 905-912, 2006.
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.2    Giachelli, C.M.3
  • 62
    • 27444443362 scopus 로고    scopus 로고
    • Reduced plasma pyro-phosphate levels in hemodialysis patients
    • Lomashvili KA, Khawandi W, O'Neill WC. Reduced plasma pyro-phosphate levels in hemodialysis patients. J Am Soc Nephrol 16: 24952500, 2005.
    • (2005) J Am Soc Nephrol , vol.16
    • Lomashvili, K.A.1    Khawandi, W.2    O'neill, W.C.3
  • 63
    • 84901924453 scopus 로고    scopus 로고
    • Vascular calcification is dependent on plasma levels of pyrophosphate
    • Lomashvili KA, Narisawa S, Millan JL, O'Neill WC. Vascular calcification is dependent on plasma levels of pyrophosphate. Kidney Int 85: 1351-1356, 2014.
    • (2014) Kidney Int , vol.85 , pp. 1351-1356
    • Lomashvili, K.A.1    Narisawa, S.2    Millan, J.L.3    O'neill, W.C.4
  • 64
    • 0042885985 scopus 로고    scopus 로고
    • Arterial media calcification in end-stage renal disease: Impact on all-cause and cardiovascular mortality
    • London GM, Guerin AP, Marchais SJ, Metivier F, Pannier B, Adda H. Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 18: 1731-1740, 2003.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1731-1740
    • London, G.M.1    Guerin, A.P.2    Marchais, S.J.3    Metivier, F.4    Pannier, B.5    Adda, H.6
  • 65
    • 0041318888 scopus 로고    scopus 로고
    • Cardiovascular calcifications in uremic patients: Clinical impact on cardiovascular function
    • London GM. Cardiovascular calcifications in uremic patients: clinical impact on cardiovascular function. J Am Soc Nephrol 14: S305-S309, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. S305-S309
    • London, G.M.1
  • 67
    • 0032891440 scopus 로고    scopus 로고
    • Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: A role for apoptosis in plaque thrombogenicity
    • Mallat Z, Hugel B, Ohan J, Leseche G, Freyssinet JM, Tedgui A. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation 99: 348-353, 1999.
    • (1999) Circulation , vol.99 , pp. 348-353
    • Mallat, Z.1    Hugel, B.2    Ohan, J.3    Leseche, G.4    Freyssinet, J.M.5    Tedgui, A.6
  • 69
    • 84877054086 scopus 로고    scopus 로고
    • Dietary vitamin K and therapeutic warfarin alter the susceptibility to vascular calcification in experimental chronic kidney disease
    • McCabe KM, Booth SL, Fu X, Shobeiri N, Pang JJ, Adams MA, Holden RM. Dietary vitamin K and therapeutic warfarin alter the susceptibility to vascular calcification in experimental chronic kidney disease. Kidney Int 83: 835-844, 2013.
    • (2013) Kidney Int , vol.83 , pp. 835-844
    • McCabe, K.M.1    Booth, S.L.2    Fu, X.3    Shobeiri, N.4    Pang, J.J.5    Adams, M.A.6    Holden, R.M.7
  • 71
    • 63849210529 scopus 로고    scopus 로고
    • Plasma osteoprotegerin is an independent risk factor for mortality and an early biomarker of coronary vascular calcification in chronic kidney disease
    • Mesquita M, Demulder A, Damry N, Melot C, Wittersheim E, Willems D, Dratwa M, Bergmann P. Plasma osteoprotegerin is an independent risk factor for mortality and an early biomarker of coronary vascular calcification in chronic kidney disease. Clin Chem Lab Med 47: 339-346, 2009.
    • (2009) Clin Chem Lab Med , vol.47 , pp. 339-346
    • Mesquita, M.1    Demulder, A.2    Damry, N.3    Melot, C.4    Wittersheim, E.5    Willems, D.6    Dratwa, M.7    Bergmann, P.8
  • 72
    • 67649678424 scopus 로고    scopus 로고
    • Vascular calcification: The killer of patients with chronic kidney disease
    • Mizobuchi M, Towler D, Slatopolsky E. Vascular calcification: the killer of patients with chronic kidney disease. J Am Soc Nephrol 20: 1453-1464, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1453-1464
    • Mizobuchi, M.1    Towler, D.2    Slatopolsky, E.3
  • 75
    • 84881024473 scopus 로고    scopus 로고
    • Role of extracellular vesicles in de novo mineralization: An additional novel mechanism of cardiovascular calcification
    • New SEP, Aikawa E. Role of extracellular vesicles in de novo mineralization: an additional novel mechanism of cardiovascular calcification. Arterioscler Thromb Vasc Biol 33: 1753-1758, 2013.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1753-1758
    • New, S.E.P.1    Aikawa, E.2
  • 78
    • 79951823118 scopus 로고    scopus 로고
    • Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease
    • Pai A, Leaf EM, El-Abbadi M, Giachelli CM. Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease. Am J Pathol 178: 764-773, 2011.
    • (2011) Am J Pathol , vol.178 , pp. 764-773
    • Pai, A.1    Leaf, E.M.2    El-Abbadi, M.3    Giachelli, C.M.4
  • 79
    • 77957884403 scopus 로고    scopus 로고
    • Matrix remodeling in vascular calcification associated with chronic kidney disease
    • Pai AS, Giachelli CM. Matrix remodeling in vascular calcification associated with chronic kidney disease. J Am Soc Nephrol 21: 16371640, 2010.
    • (2010) J Am Soc Nephrol , vol.21
    • Pai, A.S.1    Giachelli, C.M.2
  • 82
    • 70149123804 scopus 로고    scopus 로고
    • Vascular calcification and bone disease: The calcification paradox
    • Persy V, D'Haese P. Vascular calcification and bone disease: the calcification paradox. Trends Mol Med 15: 405-416, 2009.
    • (2009) Trends Mol Med , vol.15 , pp. 405-416
    • Persy, V.1    D'haese, P.2
  • 83
    • 0038422941 scopus 로고    scopus 로고
    • The inhibition of calcium phosphate precipitation by fetuin is accompanied by the formation of a fetuin-mineral complex
    • Price PA, Lim JE. The inhibition of calcium phosphate precipitation by fetuin is accompanied by the formation of a fetuin-mineral complex. J Biol Chem 278: 22144-22152, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 22144-22152
    • Price, P.A.1    Lim, J.E.2
  • 84
    • 0037483052 scopus 로고    scopus 로고
    • Biochemical characterization of the serum fetuin-mineral complex
    • Price PA, Nguyen TMT, Williamson MK. Biochemical characterization of the serum fetuin-mineral complex. J Biol Chem 278: 22153-22160, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 22153-22160
    • Price, P.A.1    Nguyen, T.M.T.2    Williamson, M.K.3
  • 85
    • 0037040254 scopus 로고    scopus 로고
    • Discovery of a high molecular weight complex of calcium, phosphate, fetuin, and matrix gamma-carboxyglutamic acid protein in the serum of etidronate-treated rats
    • Price PA, Thomas GR, Pardini AW, Figueira WF, Caputo JM, Williamson MK. Discovery of a high molecular weight complex of calcium, phosphate, fetuin, and matrix gamma-carboxyglutamic acid protein in the serum of etidronate-treated rats. J Biol Chem 277: 3926-3934, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 3926-3934
    • Price, P.A.1    Thomas, G.R.2    Pardini, A.W.3    Figueira, W.F.4    Caputo, J.M.5    Williamson, M.K.6
  • 86
    • 0021114588 scopus 로고
    • Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone
    • Price PA, Urist MR, Otawara Y. Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone. Biochem Biophys Res Commun 117: 765-771, 1983.
    • (1983) Biochem Biophys Res Commun , vol.117 , pp. 765-771
    • Price, P.A.1    Urist, M.R.2    Otawara, Y.3
  • 87
    • 0347717867 scopus 로고    scopus 로고
    • Serum levels of the fetuin-mineral complex correlate with artery calcification in the rat
    • Price PA, Williamson MK, Nguyen TMT, Than TN. Serum levels of the fetuin-mineral complex correlate with artery calcification in the rat. J Biol Chem 279: 1594-1600, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 1594-1600
    • Price, P.A.1    Williamson, M.K.2    Nguyen, T.M.T.3    Than, T.N.4
  • 88
    • 33749132161 scopus 로고    scopus 로고
    • Molecular mechanisms mediating vascular calcification: Role of matrix Gla protein
    • Proudfoot D, Shanahan CM. Molecular mechanisms mediating vascular calcification: role of matrix Gla protein. Nephrology (Carlton) 11: 455-461, 2006.
    • (2006) Nephrology (Carlton) , vol.11 , pp. 455-461
    • Proudfoot, D.1    Shanahan, C.M.2
  • 89
    • 0034711505 scopus 로고    scopus 로고
    • Apoptosis regulates human vascular calcification in vitro: Evidence for initiation of vascular calcification by apoptotic bodies
    • Proudfoot D, Skepper JN, Hegyi L, Bennett MR, Shanahan CM, Weissberg PL. Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies. Circ Res 87: 1055-1062, 2000.
    • (2000) Circ Res , vol.87 , pp. 1055-1062
    • Proudfoot, D.1    Skepper, J.N.2    Hegyi, L.3    Bennett, M.R.4    Shanahan, C.M.5    Weissberg, P.L.6
  • 92
    • 14544283020 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD
    • Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol 15: 2857-2867, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2857-2867
    • Reynolds, J.L.1    Joannides, A.J.2    Skepper, J.N.3    McNair, R.4    Schurgers, L.J.5    Proudfoot, D.6    Jahnen-Dechent, W.7    Weissberg, P.L.8    Shanahan, C.M.9
  • 94
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis—an inflammatory disease
    • Ross R. Atherosclerosis—an inflammatory disease. N Engl J Med 340: 115-126, 1999.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 95
    • 0036021056 scopus 로고    scopus 로고
    • Matrix Gla protein binding to hydroxyapatite is dependent on the ionic environment: Calcium enhances binding affinity but phosphate and magnesium decrease affinity
    • Roy ME, Nishimoto SK. Matrix Gla protein binding to hydroxyapatite is dependent on the ionic environment: calcium enhances binding affinity but phosphate and magnesium decrease affinity. Bone 31: 296-302, 2002.
    • (2002) Bone , vol.31 , pp. 296-302
    • Roy, M.E.1    Nishimoto, S.K.2
  • 97
    • 36048959129 scopus 로고    scopus 로고
    • Osteopontin: A multifunctional molecule regulating chronic inflammation and vascular disease
    • Scatena M, Liaw L, Giachelli CM. Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease. Arterioscler Thromb Vasc Biol 27: 2302-2309, 2007.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2302-2309
    • Scatena, M.1    Liaw, L.2    Giachelli, C.M.3
  • 98
    • 0029664962 scopus 로고    scopus 로고
    • The serum protein alpha2-HS glycoprotein/fetuin inhibits apatite formation in vitro and in mineralizing calvaria cells. A possible role in mineralization and calcium homeostasis
    • Schinke T, Amendt C, Trindl A, Poschke O, Miller-Esterl W, Jahnen-Dechent W. The serum protein alpha2-HS glycoprotein/fetuin inhibits apatite formation in vitro and in mineralizing calvaria cells. A possible role in mineralization and calcium homeostasis. J Biol Chem 271: 20789-20796, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 20789-20796
    • Schinke, T.1    Amendt, C.2    Trindl, A.3    Poschke, O.4    Miller-Esterl, W.5    Jahnen-Dechent, W.6
  • 102
    • 80052561697 scopus 로고    scopus 로고
    • Arterial calcification in chronic kidney disease: Key roles for calcium and phosphate
    • Shanahan CM, Crouthamel MH, Kapustin A, Giachelli CM. Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circ Res 109: 697-711, 2011.
    • (2011) Circ Res , vol.109 , pp. 697-711
    • Shanahan, C.M.1    Crouthamel, M.H.2    Kapustin, A.3    Giachelli, C.M.4
  • 103
    • 84882242928 scopus 로고    scopus 로고
    • Autophagy and matrix vesicles: New partners in vascular calcification
    • Shanahan CM. Autophagy and matrix vesicles: new partners in vascular calcification. Kidney Int 83: 984-986, 2013.
    • (2013) Kidney Int , vol.83 , pp. 984-986
    • Shanahan, C.M.1
  • 104
    • 84881167256 scopus 로고    scopus 로고
    • Phosphate: An old bone molecule but new cardiovascular risk factor
    • Shobeiri N, Adams MA, Holden RM. Phosphate: an old bone molecule but new cardiovascular risk factor. Br J Clin Pharmacol 77: 39-54, 2014.
    • (2014) Br J Clin Pharmacol , vol.77 , pp. 39-54
    • Shobeiri, N.1    Adams, M.A.2    Holden, R.M.3
  • 105
    • 84879961870 scopus 로고    scopus 로고
    • Phosphate is a vascular toxin
    • Shroff R. Phosphate is a vascular toxin. Pediatr Nephrol 28: 583-593, 2013.
    • (2013) Pediatr Nephrol , vol.28 , pp. 583-593
    • Shroff, R.1
  • 108
    • 38449092429 scopus 로고    scopus 로고
    • Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney disease
    • Sigrist MK, Taal MW, Bungay P, McIntyre CW. Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney disease. Clin J Am Soc Nephrol 2: 1241-1248, 2007.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 1241-1248
    • Sigrist, M.K.1    Taal, M.W.2    Bungay, P.3    McIntyre, C.W.4
  • 109
    • 84874459691 scopus 로고    scopus 로고
    • Serum fetuin-A concentration and fetuin-A-containing calciprotein particles in patients with chronic inflammatory disease and renal failure
    • Smith ER, Cai MM, McMahon LP, Pedagogos E, Toussaint ND, Brumby C, Holt SG. Serum fetuin-A concentration and fetuin-A-containing calciprotein particles in patients with chronic inflammatory disease and renal failure. Nephrology (Carlton) 18: 215-221, 2013.
    • (2013) Nephrology (Carlton) , vol.18 , pp. 215-221
    • Smith, E.R.1    Cai, M.M.2    McMahon, L.P.3    Pedagogos, E.4    Toussaint, N.D.5    Brumby, C.6    Holt, S.G.7
  • 111
    • 84875969761 scopus 로고    scopus 로고
    • Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage
    • Smith ER, Hanssen E, McMahon LP, Holt SG. Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage. PLoS ONE 8: e60904, 2013.
    • (2013) PLoS ONE , vol.8
    • Smith, E.R.1    Hanssen, E.2    McMahon, L.P.3    Holt, S.G.4
  • 112
    • 33846103421 scopus 로고    scopus 로고
    • Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells
    • Son BK, Kozaki K, Iijima K, Eto M, Nakano T, Akishita M, Ouchi Y. Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. Eur J Pharmacol 556: 1-8, 2007.
    • (2007) Eur J Pharmacol , vol.556 , pp. 1-8
    • Son, B.K.1    Kozaki, K.2    Iijima, K.3    Eto, M.4    Nakano, T.5    Akishita, M.6    Ouchi, Y.7
  • 114
    • 1642284407 scopus 로고    scopus 로고
    • Regulation of cardiovascular calcification
    • Speer MY, Giachelli CM. Regulation of cardiovascular calcification. Cardiovasc Pathol 13: 63-70, 2004.
    • (2004) Cardiovasc Pathol , vol.13 , pp. 63-70
    • Speer, M.Y.1    Giachelli, C.M.2
  • 115
    • 77954105508 scopus 로고    scopus 로고
    • Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogram-ming toward osteochondrogenesis
    • Speer MY, Li X, Hiremath PG, Giachelli CM. Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogram-ming toward osteochondrogenesis. J Cell Biochem 110: 935-947, 2010.
    • (2010) J Cell Biochem , vol.110 , pp. 935-947
    • Speer, M.Y.1    Li, X.2    Hiremath, P.G.3    Giachelli, C.M.4
  • 116
    • 84961040256 scopus 로고
    • Studies on fetuin, a glycoprotein of fetal serum. I. Isolation, chemical composition, and physiochemical properties
    • Spiro RG. Studies on fetuin, a glycoprotein of fetal serum. I. Isolation, chemical composition, and physiochemical properties. J Biol Chem 235: 2860-2869, 1960.
    • (1960) J Biol Chem , vol.235 , pp. 2860-2869
    • Spiro, R.G.1
  • 120
    • 0032546449 scopus 로고    scopus 로고
    • Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone
    • Tsukii K, Shima N, Mochizuki S, Yamaguchi K, Kinosaki M, Yano K, Shibata O, Udagawa N, Yasuda H, Suda T, Higashio K. Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone. Biochem Biophys Res Commun 246: 337-341, 1998.
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 337-341
    • Tsukii, K.1    Shima, N.2    Mochizuki, S.3    Yamaguchi, K.4    Kinosaki, M.5    Yano, K.6    Shibata, O.7    Udagawa, N.8    Yasuda, H.9    Suda, T.10    Higashio, K.11
  • 122
    • 0037341318 scopus 로고    scopus 로고
    • Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification
    • Tyson KL, Reynolds JL, McNair R, Zhang Q, Weissberg PL, Shanahan CM. Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification. Arterioscler Thromb Vasc Biol 23: 489-494, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 489-494
    • Tyson, K.L.1    Reynolds, J.L.2    McNair, R.3    Zhang, Q.4    Weissberg, P.L.5    Shanahan, C.M.6
  • 123
    • 0030116175 scopus 로고    scopus 로고
    • Angiographic study of stenosis and calcification of coronary vessels in long-term dialysis patients: Examination of risk factors for coronary calcification]
    • Utsunomiya M. [Angiographic study of stenosis and calcification of coronary vessels in long-term dialysis patients: examination of risk factors for coronary calcification]. Nihon Jinzo Gakkai Shi 38: 155-163,1996.
    • (1996) Nihon Jinzo Gakkai Shi , vol.38 , pp. 155-163
    • Utsunomiya, M.1
  • 124
    • 84896041322 scopus 로고    scopus 로고
    • MiR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment
    • Wen P, Cao H, Fang L, Ye H, Zhou Y, Jiang L, Su W, Xu H, He W, Dai C, Yang J. miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment. Exp Cell Res 322: 302-312, 2014.
    • (2014) Exp Cell Res , vol.322 , pp. 302-312
    • Wen, P.1    Cao, H.2    Fang, L.3    Ye, H.4    Zhou, Y.5    Jiang, L.6    Su, W.7    Xu, H.8    He, W.9    Dai, C.10    Yang, J.11
  • 125
    • 0032446940 scopus 로고    scopus 로고
    • Na+-dependent phosphate cotrans-porters: The NaPi protein families
    • Werner A, Dehmelt L, Nalbant P. Na+-dependent phosphate cotrans-porters: the NaPi protein families. J Exp Biol 201: 3135-3142, 1998.
    • (1998) J Exp Biol , vol.201 , pp. 3135-3142
    • Werner, A.1    Dehmelt, L.2    Nalbant, P.3
  • 126
    • 9644298257 scopus 로고    scopus 로고
    • Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro
    • Yang H, Curinga G, Giachelli CM. Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney Int 66: 2293-2299, 2004.
    • (2004) Kidney Int , vol.66 , pp. 2293-2299
    • Yang, H.1    Curinga, G.2    Giachelli, C.M.3


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