Enhanced ε-poly-l-lysine production by inducing double antibiotic-resistant mutations in Streptomyces albulus

Bioprocess and Biosystems Engineering

Volumn 40, Issue 2, 2017, Pages 271-283

  Wang, Liang ^a   Chen, Xusheng ^a   Wu, Guangyao ^a   Li, Shu ^b   Zeng, Xin ^a   Ren, Xidong ^a   Tang, Lei ^a   Mao, Zhonggui ^a  

^a JIANGNAN UNIVERSITY   (China)

^b Xiwang Group Company Limited   (China)

Author keywords

Double drug resistant mutation; Key enzyme activities; qRT PCR; Ribosome engineering; Streptomyces albulus FEEL 1

Indexed keywords

AMINO ACIDS; BACTERIA; BIOCHEMISTRY; ENZYMES; MACROMOLECULES; STRAIN;

BIOSYNTHESIS PATHWAYS; DOUBLE DRUG-RESISTANT MUTATION; FED-BATCH FERMENTATION; Q-RT-PCR; RESPIRATORY ACTIVITY; RIBOSOME ENGINEERING; STREPTOMYCES ALBULUS; TRANSCRIPTIONAL LEVELS;

ANTIBIOTICS;

EPSILON POLY LEVO LYSINE; GENTAMICIN; POLYLYSINE; RIFAMPICIN; STREPTOMYCIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BIOREACTOR; BREEDING METHOD; ENZYME ACTIVITY; FED BATCH FERMENTATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RPLF GENE; RPOB GENE; RPSL GENE; STREPTOMYCES ALBUS; BIOSYNTHESIS; GENETICS; METABOLISM; MUTATION; STREPTOMYCES;

DRUG RESISTANCE, BACTERIAL; GENTAMICINS; MUTATION; POLYLYSINE; RIFAMPIN; STREPTOMYCES; STREPTOMYCIN;

EID: 84994236180     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-016-1695-5     Document Type: Article

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