Mycelium differentiation and development of Streptomyces coelicolor in lab-scale bioreactors: Programmed cell death, differentiation, and lysis are closely linked to undecylprodigiosin and actinorhodin production

Bioresource Technology

Volumn 151, Issue , 2014, Pages 191-198

  Rioseras, Beatriz ^a   López García, María Teresa ^a   Yagüe, Paula ^a   Sánchez, Jesús ^a   Manteca, Ángel ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Antibiotics; Bioreactor; Differentiation; Programmed cell death; Streptomyces

Indexed keywords

ANTIBIOTICS; BIOCONVERSION; BIOREACTORS; CELL DEATH; DIFFERENTIATION (CALCULUS); FUNGI; METABOLITES; OPTIMIZATION; STRAIN;

ANTIBIOTIC PRODUCTION; BIOPHYSICAL PARAMETERS; LAB-SCALE BIOREACTORS; PROGRAMMED CELL DEATHS; SECONDARY METABOLITE PRODUCTION; SECONDARY METABOLITES; STREPTOMYCES; STREPTOMYCES COELICOLOR;

BACTERIA;

ACTINORHODINE; ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; UNDECYLPRODIGIOSIN;

ANTIBIOTICS; APOPTOSIS; BACTERIUM; BIOLOGICAL PRODUCTION; BIOPHYSICS; BIOREACTOR; FERMENTATION; LIFE CYCLE; MORPHOLOGY; OPTIMIZATION; SECONDARY METABOLITE; VIABILITY;

APOPTOSIS; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BIOREACTOR; CELL DIFFERENTIATION; CYTOLYSIS; MUTAGENESIS; MYCELIUM; NONHUMAN; PRIORITY JOURNAL; SPOROGENESIS; STREPTOMYCES COELICOLOR;

STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCINEAE;

ANTIBIOTICS; BIOREACTOR; DIFFERENTIATION; DISSOLVED OXYGEN TENSION; DOT; FIRST COMPARTMENTALIZED MYCELIUM; MI; MII; OTR; OUR; OXYGEN TRANSFER RATES; OXYGEN UPTAKE RATE; PCD; PHOTOMULTIPLIER TUBE; PI; PMT; PROGRAMMED CELL DEATH; PROPIDIUM IODIDE; SECOND MULTINUCLEATED MYCELIUM; STREPTOMYCES;

ANTHRAQUINONES; ANTI-BACTERIAL AGENTS; APOPTOSIS; BATCH CELL CULTURE TECHNIQUES; BIOREACTORS; FERMENTATION; MYCELIUM; PRODIGIOSIN; STREPTOMYCES COELICOLOR; TIME FACTORS;

EID: 84887510155     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2013.10.068     Document Type: Article

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