Antidiabetic effects of Mangifera indica Kernel Flour-supplemented diet in streptozotocin-induced type 2 diabetes in rats

Food Science and Nutrition

Volumn 4, Issue 6, 2016, Pages 828-839

  Irondi, Emmanuel A ^a,b   Oboh, Ganiyu ^a   Akindahunsi, Afolabi A ^a  

^a FEDERAL UNIVERSITY OF TECHNOLOGY   (Nigeria)

^b KWARA STATE UNIVERSITY   (Nigeria)

Author keywords

Hyperglycemia; hyperlipidemia; Mangifera indica kernel; plasma electrolytes; type 2 diabetes

Indexed keywords

EID: 84994048845     PISSN: None     EISSN: 20487177     Source Type: Journal    
DOI: 10.1002/fsn3.348     Document Type: Article

References (73)

1. Ahmed, I., and B. Goldstein. 2006. Diabetes mellitus. Clin. Dermatol. 24:237–246.
2. Ahmed, O. M., A. Abdel-Moneim, I. Abulyazid, and A. M. Mahmoud. 2010. Antihyperglycemic, anti-hyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens and rutin in nicotinamide/streptozotocin diabetic albino rats. Diabetolo. Croat. 39:15–32.
3. Annadurai, T., A. Vasanthakumar, P. Geraldine, and P. A. Thomas. 2014. Variations in erythrocyte antioxidant levels and lipid peroxidation status and in serum lipid profile parameters in relation to blood haemoglobin A1c values in individuals with type 2 diabetes mellitus. Diabetes Res. Clin. Pract. 105:58–69.
4. Arts, I. C. W., and P. C. H. Hollman. 2005. Polyphenols and disease risk in epidemiologic studies. Am. J. Clin. Nutr. 81:317–325.
5. Association of Official Analytical Chemists, AOAC. 2005. Official methods of analysis of association of analytical chemists international. Pp.152–154 252 in Horwitz, W. ed. 18th ed. AOAC International, Washington D.C.
6. Bernadette, B. A., C. Sam, J. Chong, C. U. Culing, W. Clinton, R. Tatjana, S. V. Mitchell, et al. 2008. Diabetes, fasting glucose levels and risk ischaemic and vascular events. Diab. Care 31:1132–1137.
7. Bhowmik, A., L. A. Khan, M. Akhter, and B. Rokeya. 2009. Studies on the antidiabetic effects of Mangifera indica stem-barks and leaves on nondiabetic, type 1 and type 2 diabetic model rats. Bangladesh J Pharmacol. 4:110–114.
8. Cabrera, C., R. Artacho, and R. Giménez. 2006. Beneficial effects of green tea - a review. J. Am. Coll. Nutr. 25:79–99.
9. Chahil, T. J., and H. N. Ginsberg. 2006. Diabetic dyslipidaemia. Endocrinol. Metab. Clin. North Am. 35:491–510.
10. Chehade, J. M., M. Gladysz, and A. D. Mooradian. 2013. Dyslipidaemia in type 2 diabetes: prevalence, pathophysiology, and management. Drugs 73:327–339.
11. Clegg, M. S., C. L. Keen, B. Lonnerdal, and L. S. Hurley. 1981. Influence of ashing techniques on the analysis of trace elements in animal tissue. Biol. Trace Elem. Res. 3:107–115.
12. Collier, C. A., C. R. Bruce, A. C. Smith, G. Lopaschuk, and D. J. Dyck. 2006. Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 291:E182–E189.
13. Danaei, G., M. Finucane, Y. Lu, G. M. Singh, M. J. Cowan, C. J. Paciorek, et al. 2011. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378:31–40.
14. Diwan, A. G., A. B. Pradhan, D. Lingojwar, K. K. Krishna, P. Singh, and S. I. Almelkar. 2006. Serum zinc, chromium and magnesium levels in type-2 diabetes. Int. J. Diab. Dev. Ctries. 26:122–123.
15. Eddy, N. O., and C. L. Udoh. 2005. Proximate evaluation of nutritional value of some soup thickeners. ChemClass J. 2:12–14.
16. Ene, A. C., E. A. Nwankwo, and L. M. Samdi. 2007. Alloxan-induced diabetes in arts and the effects of black caraway (Caramcarvi L.) oil on their body weight. Res. J. Med. Sci. 2:48–52.
17. Food Agriculture Organization FAO. 2010. Statistical database. Rome, Italy. http://faostat.fao.org (accessed 15 December 2011).
18. Friedewald, W. T., R. I. Levy, and D. S. Fredrickson. 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18:499–502.
19. Garcia, D., J. Leiro, R. Delgado, et al. 2003. Mango L. extract (Vimang) and mangiferin modulate mouse humoral immune response. Phytother. Res. 17:1182–1187.
20. ®). Pharmacol. Res. 50:143–149.
21. Gray, S. P., and M. E. Cooper. 2011. Diabetic nephropathy in 2010: alleviating the burden of diabetic nephropathy. Nat. Rev. Nephrol. 7:71–73.
22. Grover, J. K., S. Yadav, and V. Vats. 2002. Medicinal plants of India with antidiabetic potential. J. Ethnopharmacol. 81:81–100.
23. Guerrero-Romero, F., and M. Rodríguez-Morán. 2006. Hypomagnesemia, oxidative stress, inflammation and metabolic syndrome. Diab/Metab. Res. Rev. 22:471–476.
24. Idris, A. S., K. F. H. Mekky, B. E. E. Abdalla, and K. A. Ali. 2011. Liver function tests in type 2 Sudanese diabetic patients. Int. J. Nutr. Metab. 3:17–21.
25. International Diabetes Federation. 2009. The diabetes atlas, 4th ed. Brussels, International Diabetes Federation.
26. Irondi, A. E., G. Oboh, A. A. Akindahunsi, A. A. Boligon, and M. L. Athayde. 2014. Phenolic composition and inhibitory activity of Mango and Horse-eye bean seeds extracts against key enzymes linked to the pathology and complications of type 2 diabetes. Asian Pac. J. Trop. Biomed. 4:903–910.
27. Iwai, K., M. Y. Kim, A. Onodera, and H. Matsue. 2006. Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum Thunb. J. Agric. Food Chem. 54:4588–4592.
28. Iwalokun, B. I., J. A. Alibi-Sofunde, T. Odunala, O. A. Magbagbeola, and A. I. Akinwande. 2006. Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice. J. Med. Foods 9:526–530.
29. Jain, C., A. Singh, P. Kumar, and K. Gautam. 2014. Anti-diabetic potential of flavonoids and other crude extracts of stem bark of Mango Linn: a comparative study. J. Sci. Innovative Res. 3:21–27.
30. Jayasri, M. A., S. Gunasekaran, A. Radha, and T. L. Mathew. 2008. Antidiabetic effect of Costus pictus leaves in normal and streptozotocin-induced diabetic rats. Int. J. Diab. Metab. 16:117–122.
31. Kaur, G., P. Kamboj, and A. N. Kalia. 2011. Antidiabetic and anti-hypercholesterolemic effects of aerial parts of Sida cordifolia Linn. on Streptozotocin-induced diabetic rats. Indian J. Nat. Prod. Resour. 2: 428–434.
32. Kirpichnikov, D., S. I. McFarlane, and J. R. Sowers. 2002. Metformin: an update. Ann. Intern. Med. 137:25–33.
33. Kumar, S., D. K. Das, and U. S. Prasad. 1991. Free amino acid composition in fruit of two mango cultivars during maturation and ripening. Indian J. Plant Physiol. 34:1–6.
34. Kundu, D., A. Roy, T. Mandal, U. Bandyopadhyay, E. Ghosh, and D. Ray. 2013. Relation of microalbuminuria to glycosylated haemoglobin and duration of type 2 diabetes. Nig. J. Clin. Pract. 16:216–220.
35. Laakso, M. 2001. Insulin resistance and its impact on the approach to therapy of T2D. Int. J. Clin. Pract. (Suppl. 121): 8–12.
36. Lenzen, S. 2008. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetol 51:216–226.
37. Li, G., P. Zhang, J. Wang, E. W. Gregg, W. Yang, Q. Gong, et al. 2008. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing diabetes prevention study: a 20-year follow-up study. Lancet 371:1783–1789.
38. Lowry, O. H., N. J. Rosenbrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with folin phenol reagent. J. Biol. Chem. 193:265–270.
39. Maisuthisakul, P., and M. H. Gordon. 2009. Antioxidant and tyrosinase inhibitory activity of mango seed kernel by product. Food Chem. 117:332–341.
40. Mansour, H. A., A. Newairy, S. A. Yousef, and M. I. Sheweita. 2002. Biochemical study on the effects of some Egyptian herbs in alloxan-induced diabetic rats. Toxicology 170:221–228.
41. Marianna, M., D. Chaonan, H. QingPing, L. Yanling, and L. Ping-A. 2006. Streptozotocin-induced diabetes causes astrocyte death after ischemia and reperfusion injury. Diabetes 55:349–355.
42. Masood, N., G. H. Baloch, R. A. Ghori, I. A. Memon, M. A. Memon, and M. S. Memon 2009. Serum zinc and magnesium in type-2 diabetic patients. J. Coll. Physicians Surg. Pak. 19:483–486.
43. Murray, R. K., D. K. Granner, and P. A. Mayesa. 2000. Harper's biochemistry, 25th ed. Appleton and Lange, Stamford, CT.
44. Murugan, P., and L. Pari. 2007. Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats. Basic Clin. Pharmacol. Toxicol. 101:241–245.
45. Muruganandan, S., K. Scrinivasan, S. Gupta, P. K. Gupta, and J. Lal. 2005. Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats. J. Ethnopharmacol. 97:497–501.
46. Nwanjo, H. U. 2007. Studies on the effect of aqueous extract of Phyllanthus niruri on plasma glucose level and some hepatospecific markers in diabetic Wistar rats. Int. J. Lab. Med. 2:1–18.
47. Oboh, G., A. J. Akinyemi, A. O. Ademiluyi, and S. A. Adefegha. 2010. Inhibitory effects of aqueous extract of two varieties of ginger on some key enzymes linked to type-2 diabetes in vitro. J. Food Nutr. Res. 49:14–20.
48. Ohkawa, H., N. Ohishi, and K. Yagi. 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analy. Biochem. 95:351–358.
49. Ojewole, J. A. O. 2005. Antiinflammatory, analgesic and hypoglycemic effects of Mangifera indica Linn. (Anacardiaceae) stem-bark aqueous extract. Methods Find. Exp. Clin. Pharmacol. 27:547–554.
50. Ong, K. C., and H. E. Khoo. 2000. Effects of myricetin on glycemia and glycogen metabolism in diabetic rats. Life Sci. 67:1695–1705.
51. Orhan, N., A. Berkkan, D. D. Orhan, M. Aslan, and F. Ergun. 2011. Effects of Juniperus oxycedrus ssp. oxycedrus on tissue lipid peroxidation, trace elements (Cu, Zn, Fe) and blood glucose levels in experimental diabetes. J. Ethnopharmacol. 133:759–764.
52. Parveen, K., R. Khan, and W. A. Siddiqui. 2011. Antidiabetic effects afforded by Terminalia arjuna in high fat-fed and streptozotocin-induced type 2 diabetic rats. Int. J. Diab. Metab. 19:23–33.
53. Pedersen, T. R. 2001. Low density lipoprotein cholesterol lowering is and will be the key to the future of lipid management. Am. J. Cardiol. 87:8B–12B.
54. Perez-Gutierrez, R. M., and J. M. Mota Flores. 2010. Attenuation of hyperglycaemia and hyperlipidemia in streptozotocin-induced diabetic rats by chloroform extract of fruits of Ferocactus latispinus and Ferocactus histrix. Bol. Latinoam. Caribe Plant. Med. Aromat. 9:475–484.
55. Prabhu, K. S., R. Lobo, and A. Shirwaikar. 2008. Antidiabetic properties of the alcoholic extract of Sphaeranthus indicus in streptozotocin-nicotinamide diabetic rats. J. Pharm. Pharmacol. 60:909–916.
56. Purseglove, J. W. 1991. P. 29Tropical crops: dicotyledons. Harlow, Longman Scientific and Technical Publishers, Harlow.
57. Rahman, I. 2003. Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases. J. Biochem. Mol. Biol. 36:95–109.
58. Reed, M. J., K. Meszaros, L. J. Entes, M. D. Claypool, J. G. Pinkett, T. M. Gadbois, et al. 2000. A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat. Metabolism 49:1390–1394.
59. Ribeiro, S. M. R., L. C. A. Barbosa, J. Queiroz, H. M. Knodler, and A. Schieber. 2008. Phenolic compounds and antioxidant capacity of Brazilian mango (Mango L.) varieties. Food Chem. 110:620–626.
60. Rohlfing, C. L., R. R. Little, H. Wiedmeyer, J. D. England, R. Madsen, M. I. Harris, et al. 2000. Use of GHb (HbA1c) in screening for undiagnosed diabetes in the U.S. population. Diab. Care 23:187–191.
61. Saudek, C. D., R. R. Kalyani, and R. L. Derr. 2005. Assessment of glycemia in diabetes mellitus: haemoglobin A1c. J. Assoc. Physicians India 53:299–305.
62. Selvan, V. T., L. Manikandan, K. G. P. Senthil, R. Suresh, and B. Kakoti. 2008. Antidiabetic and antioxidant effect of methanol extract of Artanema sesamoides in streptatozocin-induced diabetic rats. Int. J. Appl. Res. Nat. Prod. 1:25–33.
63. Shalaby, E. A., and S. M. M. Shanab. 2013. Antioxidant compounds, assays of determination and mode of action. Afr. J. Pharm. Pharmacol. 7:528–539.
64. Shivanna, N., M. Naika, F. Khanum, and V. K. Kaul. 2013. Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana. J. Diab. Complications 27:103–113.
65. Singh, N. S., P. Vats, S. Suri, R. Shyam, M. M. L. Kumria, S. Ranganathan, et al. 2001. Effect of an antidiabetic extract of Catharanthus roseus on enzymic activities in streptozotocin induced diabetic rats. J. Ethnopharmacol. 76:269–277.
66. Srinivasan, K., B. Viswanad, L. Asrat, C. L. Kaul, and P. Ramarao. 2005. Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacol. Res. 52:313–320.
67. Standefer, C. J., and P. R. Eaton. 1983. Evaluation of a colourimetric method for determination of glycosylated hemoglobin. Clin. Chem. 29:135–140.
68. Szkudelski, T. 2001. The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas. Physiol. Res. 50:537–546.
69. Viktorínová, A., E. Tošerová, M. Križko, and Z. Dˇuracˇková. 2009. Altered metabolism of copper, zinc, and magnesium is associated with increased levels of glycated haemoglobin in patients with diabetes mellitus. Metab. Clin. Exp. 58:1477–1482.
70. Wälti, M. K., M. B. Zimmermann, G. A. Spinas, and R. F. Hurrell. 2003. Low plasma magnesium in type 2 diabetes. Swiss Med. Wkly 133:289–292.
71. Xu, Y., Z. He, and G. L. King. 2005. Introduction of hyperglycaemia and dyslipidaemia in the pathogenesis of diabetic vascular complications. Curr. Diab. Rep. 5:91–97.
72. Zhang, W., J. Zhao, J. Wang, X. Pang, X. Zhuang, X. Zhu, et al. 2010. Hypoglycemic effect of aqueous extract of sea buckthorn (Hippophae rhamnoides L.) seed residues in streptozotocin-induced diabetic rats. Phytother. Res. 24:228–232.
73. Zia, T., S. N. Hasnain, and S. K. Hasan. 2001. Evaluation of the oral hypoglycemic effect of Trigonella foenum-graecum in normal mice. J. Ethanopharmacol. 75:191–195.