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Volumn 538, Issue 7626, 2016, Pages 518-522

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

(21)  Hawkins, Edwin D a,b,c   Duarte, Delfim a,d   Akinduro, Olufolake a   Khorshed, Reema A a   Passaro, Diana d   Nowicka, Malgorzata e   Straszkowski, Lenny f   Scott, Mark K a,b   Rothery, Steve a   Ruivo, Nicola a   Foster, Katie d   Waibel, Michaela c,g   Johnstone, Ricky W c,g   Harrison, Simon J c,g   Westerman, David A c,g   Quach, Hang c,h   Gribben, John i   Robinson, Mark D e   Purton, Louise E c,f   Bonnet, Dominique d   more..


Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINASE; CHEMOKINE RECEPTOR CXCR4; DEXAMETHASONE; GREEN FLUORESCENT PROTEIN; NESTIN; NOTCH RECEPTOR; VINCRISTINE;

EID: 84994005268     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19801     Document Type: Article
Times cited : (154)

References (36)
  • 1
    • 84928485157 scopus 로고    scopus 로고
    • Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development
    • Bowers, M. et al. Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development. Blood 125, 2678-2688 (2015).
    • (2015) Blood , vol.125 , pp. 2678-2688
    • Bowers, M.1
  • 2
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone, A. et al. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science 322, 1861-1865 (2008).
    • (2008) Science , vol.322 , pp. 1861-1865
    • Colmone, A.1
  • 3
    • 84902508035 scopus 로고    scopus 로고
    • Leukemia propagating cells rebuild an evolving niche in response to therapy
    • Duan, C. W. et al. Leukemia propagating cells rebuild an evolving niche in response to therapy. Cancer Cell 25, 778-793 (2014).
    • (2014) Cancer Cell , vol.25 , pp. 778-793
    • Duan, C.W.1
  • 4
    • 84905741878 scopus 로고    scopus 로고
    • Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche
    • Hanoun, M. et al. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. Cell Stem Cell 15, 365-375 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 365-375
    • Hanoun, M.1
  • 5
    • 35948984135 scopus 로고    scopus 로고
    • Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
    • Ishikawa, F. et al. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region. Nature Biotechnol. 25, 1315-1321 (2007).
    • (2007) Nature Biotechnol. , vol.25 , pp. 1315-1321
    • Ishikawa, F.1
  • 6
    • 77749317560 scopus 로고    scopus 로고
    • Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML
    • Saito, Y. et al. Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML. Nature Biotechnol. 28, 275-280 (2010).
    • (2010) Nature Biotechnol. , vol.28 , pp. 275-280
    • Saito, Y.1
  • 7
    • 84884164883 scopus 로고    scopus 로고
    • Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
    • Schepers, K. et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell 13, 285-299 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 285-299
    • Schepers, K.1
  • 8
    • 84859832491 scopus 로고    scopus 로고
    • Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia
    • Zhang, B. et al. Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia. Cancer Cell 21, 577-592 (2012).
    • (2012) Cancer Cell , vol.21 , pp. 577-592
    • Zhang, B.1
  • 9
    • 38349086394 scopus 로고    scopus 로고
    • CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells
    • Jin, L. et al. CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells. Mol. Cancer Ther. 7, 48-58 (2008).
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 48-58
    • Jin, L.1
  • 10
    • 84860767803 scopus 로고    scopus 로고
    • Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib
    • Weisberg, E. et al. Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib. Leukemia 26, 985-990 (2012).
    • (2012) Leukemia , vol.26 , pp. 985-990
    • Weisberg, E.1
  • 11
    • 77950356588 scopus 로고    scopus 로고
    • Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
    • Sanda, T. et al. Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia. Blood 115, 1735-1745 (2010).
    • (2010) Blood , vol.115 , pp. 1735-1745
    • Sanda, T.1
  • 12
    • 5044225888 scopus 로고    scopus 로고
    • Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
    • Weng, A. P. et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306, 269-271 (2004).
    • (2004) Science , vol.306 , pp. 269-271
    • Weng, A.P.1
  • 13
    • 40749150603 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • Pui, C. H., Robison, L. L. & Look, A. T. Acute lymphoblastic leukaemia. Lancet 371, 1030-1043 (2008).
    • (2008) Lancet , vol.371 , pp. 1030-1043
    • Pui, C.H.1    Robison, L.L.2    Look, A.T.3
  • 14
    • 58149260269 scopus 로고    scopus 로고
    • Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
    • Lo Celso, C. et al. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature 457, 92-96 (2009).
    • (2009) Nature , vol.457 , pp. 92-96
    • Lo Celso, C.1
  • 15
    • 84903999646 scopus 로고    scopus 로고
    • In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells
    • Rashidi, N. M. et al. In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells. Blood 124, 79-83 (2014).
    • (2014) Blood , vol.124 , pp. 79-83
    • Rashidi, N.M.1
  • 16
    • 84908294364 scopus 로고    scopus 로고
    • In vivo 4-dimensional tracking of hematopoietic stem and progenitor cells in adult mouse calvarial bone marrow
    • Scott, M. K., Akinduro, O. & Lo Celso, C. In vivo 4-dimensional tracking of hematopoietic stem and progenitor cells in adult mouse calvarial bone marrow. J. Vis. Exp. 91, e51683 (2014).
    • (2014) J. Vis. Exp. , vol.91 , pp. e51683
    • Scott, M.K.1    Akinduro, O.2    Lo Celso, C.3
  • 17
    • 0036133690 scopus 로고    scopus 로고
    • Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage
    • Kalajzic, I. et al. Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage. J. Bone Miner. Res. 17, 15-25 (2002).
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 15-25
    • Kalajzic, I.1
  • 18
    • 68849117424 scopus 로고    scopus 로고
    • Identification of differentially expressed genes between osteoblasts and osteocytes
    • Paic, F. et al. Identification of differentially expressed genes between osteoblasts and osteocytes. Bone 45, 682-692 (2009).
    • (2009) Bone , vol.45 , pp. 682-692
    • Paic, F.1
  • 19
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • Méndez-Ferrer, S. et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466, 829-834 (2010).
    • (2010) Nature , vol.466 , pp. 829-834
    • Méndez-Ferrer, S.1
  • 20
    • 78049529488 scopus 로고    scopus 로고
    • Glucocorticoid use in acute lymphoblastic leukaemia
    • Inaba, H. & Pui, C. H. Glucocorticoid use in acute lymphoblastic leukaemia. Lancet Oncol. 11, 1096-1106 (2010).
    • (2010) Lancet Oncol. , vol.11 , pp. 1096-1106
    • Inaba, H.1    Pui, C.H.2
  • 21
    • 57149118627 scopus 로고    scopus 로고
    • Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia
    • Mullighan, C. G. et al. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science 322, 1377-1380 (2008).
    • (2008) Science , vol.322 , pp. 1377-1380
    • Mullighan, C.G.1
  • 22
    • 84886509253 scopus 로고    scopus 로고
    • Multimodal imaging reveals structural and functional heterogeneity in different bone marrow compartments: Functional implications on hematopoietic stem cells
    • Lassailly, F., Foster, K., Lopez-Onieva, L., Currie, E. & Bonnet, D. Multimodal imaging reveals structural and functional heterogeneity in different bone marrow compartments: functional implications on hematopoietic stem cells. Blood 122, 1730-1740 (2013).
    • (2013) Blood , vol.122 , pp. 1730-1740
    • Lassailly, F.1    Foster, K.2    Lopez-Onieva, L.3    Currie, E.4    Bonnet, D.5
  • 23
    • 1942457308 scopus 로고    scopus 로고
    • Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
    • Visnjic, D. et al. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood 103, 3258-3264 (2004).
    • (2004) Blood , vol.103 , pp. 3258-3264
    • Visnjic, D.1
  • 24
    • 84908587480 scopus 로고    scopus 로고
    • Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts
    • Krevvata, M. et al. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts. Blood 124, 2834-2846 (2014).
    • (2014) Blood , vol.124 , pp. 2834-2846
    • Krevvata, M.1
  • 25
    • 35548932872 scopus 로고    scopus 로고
    • A global doublefluorescent cre reporter mouse
    • Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L. & Luo, L. A global doublefluorescent Cre reporter mouse. Genesis 45, 593-605 (2007).
    • (2007) Genesis , vol.45 , pp. 593-605
    • Muzumdar, M.D.1    Tasic, B.2    Miyamichi, K.3    Li, L.4    Luo, L.5
  • 26
    • 33748768971 scopus 로고    scopus 로고
    • Distinct roles for hedgehog and canonical wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
    • Rodda, S. J. & McMahon, A. P. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development 133, 3231-3244 (2006).
    • (2006) Development , vol.133 , pp. 3231-3244
    • Rodda, S.J.1    McMahon, A.P.2
  • 27
    • 84900297489 scopus 로고    scopus 로고
    • Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia
    • Hawkins, E. D. et al. Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia. PLoS ONE 9, e87376 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e87376
    • Hawkins, E.D.1
  • 28
    • 0033796150 scopus 로고    scopus 로고
    • Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1
    • Aster, J. C. et al. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. Mol. Cell. Biol. 20, 7505-7515 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7505-7515
    • Aster, J.C.1
  • 29
    • 58149336788 scopus 로고    scopus 로고
    • Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
    • Real, P. J. et al. Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia. Nature Med. 15, 50-58 (2009).
    • (2009) Nature Med. , vol.15 , pp. 50-58
    • Real, P.J.1
  • 30
    • 78650068497 scopus 로고    scopus 로고
    • Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance
    • Chiu, P. P., Jiang, H. & Dick, J. E. Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance. Blood 116, 5268-5279 (2010).
    • (2010) Blood , vol.116 , pp. 5268-5279
    • Chiu, P.P.1    Jiang, H.2    Dick, J.E.3
  • 31
    • 78651092929 scopus 로고    scopus 로고
    • In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow
    • Lo Celso, C., Lin, C. P. & Scadden, D. T. In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow. Nature Protocols 6, 1-14 (2011).
    • (2011) Nature Protocols , vol.6 , pp. 1-14
    • Lo Celso, C.1    Lin, C.P.2    Scadden, D.T.3
  • 32
    • 84937523490 scopus 로고    scopus 로고
    • Automated identification and localization of hematopoietic stem cells in 3D intravital microscopy data
    • Khorshed, R. A. et al. Automated identification and localization of hematopoietic stem cells in 3D intravital microscopy data. Stem Cell Reports 5, 139-153 (2015).
    • (2015) Stem Cell Reports , vol.5 , pp. 139-153
    • Khorshed, R.A.1
  • 33
    • 77952987028 scopus 로고    scopus 로고
    • Software for beadbased registration of selective plane illumination microscopy data
    • Preibisch, S., Saalfeld, S., Schindelin, J. & Tomancak, P. Software for beadbased registration of selective plane illumination microscopy data. Nature Methods 7, 418-419 (2010).
    • (2010) Nature Methods , vol.7 , pp. 418-419
    • Preibisch, S.1    Saalfeld, S.2    Schindelin, J.3    Tomancak, P.4
  • 34
    • 77957230671 scopus 로고    scopus 로고
    • A framework for oligonucleotide microarray preprocessing
    • Carvalho, B. S. & Irizarry, R. A. A framework for oligonucleotide microarray preprocessing. Bioinformatics 26, 2363-2367 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 2363-2367
    • Carvalho, B.S.1    Irizarry, R.A.2
  • 35
    • 84926507971 scopus 로고    scopus 로고
    • Limma powers differential expression analyses for RNA-sequencing and microarray studies
    • Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. e47
    • Ritchie, M.E.1
  • 36
    • 37649019847 scopus 로고    scopus 로고
    • Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data
    • Hawkins, E. D. et al. Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data. Nature Protocols 2, 2057-2067 (2007).
    • (2007) Nature Protocols , vol.2 , pp. 2057-2067
    • Hawkins, E.D.1


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