Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development

Blood

Volumn 125, Issue 17, 2015, Pages 2678-2688

  Bowers, Marisa ^a   Zhang, Bin ^a   Ho, Yinwei ^a   Agarwal, Puneet ^b   Chen, Ching Cheng ^a   Bhatia, Ravi ^b  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; CALCIUM BINDING PROTEIN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; SERRATE PROTEINS; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SURVIVAL; CARCINOGENESIS; CELL FUNCTION; CELL RENEWAL; CELL SUBPOPULATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; ABLATION THERAPY; ANIMAL; BONE MARROW; CANCER STEM CELL; CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CYTOLOGY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ABLATION TECHNIQUES; ANIMALS; ANTIGENS, CD; BONE MARROW; CALCIUM-BINDING PROTEINS; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; NEOPLASTIC STEM CELLS; OSTEOBLASTS;

EID: 84928485157     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-06-582924     Document Type: Article

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