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Volumn 139, Issue , 2016, Pages 253-270

The impact of fraudulent and irreproducible data to the translational research crisis – solutions and implementation

Author keywords

60th Anniversary Journal of Neurochemistry; clinical trials; data reproducibility; scholarly publishing; statistics

Indexed keywords

ALTEPLASE; MEASLES MUMPS RUBELLA VACCINE; TAR DNA BINDING PROTEIN;

EID: 84993990232     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13844     Document Type: Article
Times cited : (35)

References (64)
  • 3
    • 84975246894 scopus 로고    scopus 로고
    • 1,500 scientists lift the lid on reproducibility
    • Baker M. (2016) 1,500 scientists lift the lid on reproducibility. Nature News 533, 452–454.
    • (2016) Nature News , vol.533 , pp. 452-454
    • Baker, M.1
  • 4
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
    • Bensimon G., Lacomblez L. and Meininger V. (1994) A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N. Engl. J. Med. 330, 585–591.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 5
    • 84920502575 scopus 로고    scopus 로고
    • A randomized trial of intraarterial treatment for acute ischemic stroke
    • Berkhemer O. A., Fransen P. S., Beumer D. et al. (2015) A randomized trial of intraarterial treatment for acute ischemic stroke. N. Engl. J. Med. 372, 11–20.
    • (2015) N. Engl. J. Med. , vol.372 , pp. 11-20
    • Berkhemer, O.A.1    Fransen, P.S.2    Beumer, D.3
  • 6
    • 84867089591 scopus 로고    scopus 로고
    • Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial
    • Bustamante A., Giralt D., García-Bonilla L., Campos M., Rosell A. and Montaner J. (2012) Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial. J. Neurochem. 123, 217–225.
    • (2012) J. Neurochem. , vol.123 , pp. 217-225
    • Bustamante, A.1    Giralt, D.2    García-Bonilla, L.3    Campos, M.4    Rosell, A.5    Montaner, J.6
  • 7
    • 84993979084 scopus 로고    scopus 로고
    • Statistical rigor and the perils of chance
    • Button K. S. (2016) Statistical rigor and the perils of chance. eNeuro, 3, 1–4.
    • (2016) eNeuro , vol.3 , pp. 1-4
    • Button, K.S.1
  • 9
    • 84924663845 scopus 로고    scopus 로고
    • Endovascular therapy for ischemic stroke with perfusion-imaging selection
    • Campbell B. C., Mitchell P. J., Kleinig T. J. et al. (2015) Endovascular therapy for ischemic stroke with perfusion-imaging selection. N. Engl. J. Med. 372, 1009–1018.
    • (2015) N. Engl. J. Med. , vol.372 , pp. 1009-1018
    • Campbell, B.C.1    Mitchell, P.J.2    Kleinig, T.J.3
  • 10
    • 67649649676 scopus 로고    scopus 로고
    • Avoidable waste in the production and reporting of research evidence
    • Chalmers I. and Glasziou P. (2009) Avoidable waste in the production and reporting of research evidence. The Lancet 374, 86–89.
    • (2009) The Lancet , vol.374 , pp. 86-89
    • Chalmers, I.1    Glasziou, P.2
  • 13
    • 78651383689 scopus 로고    scopus 로고
    • How the case against the MMR vaccine was fixed
    • Deer B. (2011a) How the case against the MMR vaccine was fixed. BMJ 342, c5347.
    • (2011) BMJ , vol.342 , pp. c5347
    • Deer, B.1
  • 14
    • 81055138923 scopus 로고    scopus 로고
    • Pathology reports solve “new bowel disease” riddle
    • Deer B. (2011b) Pathology reports solve “new bowel disease” riddle. BMJ 343, d6823.
    • (2011) BMJ , vol.343 , pp. d6823
    • Deer, B.1
  • 15
    • 78751687890 scopus 로고    scopus 로고
    • Secrets of the MMR scare. How the vaccine crisis was meant to make money
    • Deer B. (2011c) Secrets of the MMR scare. How the vaccine crisis was meant to make money. BMJ 342, c5258.
    • (2011) BMJ , vol.342 , pp. c5258
    • Deer, B.1
  • 16
    • 78751684917 scopus 로고    scopus 로고
    • Secrets of the MMR scare. The Lancet's two days to bury bad news
    • Deer B. (2011d) Secrets of the MMR scare. The Lancet's two days to bury bad news. BMJ 342, c7001.
    • (2011) BMJ , vol.342 , pp. c7001
    • Deer, B.1
  • 17
    • 60549106857 scopus 로고    scopus 로고
    • Identity crisis
    • Editorial (2009) Identity crisis. Nature 457, 935–936.
    • (2009) Nature , vol.457 , pp. 935-936
  • 18
    • 84867637990 scopus 로고    scopus 로고
    • Misconduct accounts for the majority of retracted scientific publications
    • Fang F. C., Steen R. G. and Casadevall A. (2012) Misconduct accounts for the majority of retracted scientific publications. Proc. Natl Acad. Sci. 109, 17028–17033.
    • (2012) Proc. Natl Acad. Sci. , vol.109 , pp. 17028-17033
    • Fang, F.C.1    Steen, R.G.2    Casadevall, A.3
  • 19
    • 80053933087 scopus 로고    scopus 로고
    • The vaccine-autism connection: a public health crisis caused by unethical medical practices and fraudulent science
    • Flaherty D. K. (2011) The vaccine-autism connection: a public health crisis caused by unethical medical practices and fraudulent science. Ann. Pharmacother. 45, 1302–1304.
    • (2011) Ann. Pharmacother. , vol.45 , pp. 1302-1304
    • Flaherty, D.K.1
  • 22
    • 84924691962 scopus 로고    scopus 로고
    • Randomized assessment of rapid endovascular treatment of ischemic stroke
    • Goyal M., Demchuk A. M., Menon B. K. et al. (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N. Engl. J. Med. 372, 1019–1030.
    • (2015) N. Engl. J. Med. , vol.372 , pp. 1019-1030
    • Goyal, M.1    Demchuk, A.M.2    Menon, B.K.3
  • 23
    • 84964412178 scopus 로고    scopus 로고
    • Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
    • Goyal M., Menon B. K., van Zwam W. H. et al. (2016) Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. The Lancet 387, 1723–1731.
    • (2016) The Lancet , vol.387 , pp. 1723-1731
    • Goyal, M.1    Menon, B.K.2    van Zwam, W.H.3
  • 24
    • 84993925011 scopus 로고    scopus 로고
    • The challenges for scientific publishing, 60 years on
    • Hausmann L., Murphy S. and on behalf of the Publication Committee of the ISN (2016) The challenges for scientific publishing, 60 years on. J. Neurochem. 139 (Suppl. 2), 280–287.
    • (2016) J. Neurochem. , vol.139 , Issue.2 , pp. 280-287
    • Hausmann, L.1    Murphy, S.2
  • 27
    • 84905816851 scopus 로고    scopus 로고
    • Measles-mumps-rubella vaccination timing and autism among young African American boys: a reanalysis of CDC data
    • Hooker B. S. (2014) Measles-mumps-rubella vaccination timing and autism among young African American boys: a reanalysis of CDC data. Transl. Neurodegener 3, 16.
    • (2014) Transl. Neurodegener , vol.3 , pp. 16
    • Hooker, B.S.1
  • 28
    • 1542345667 scopus 로고    scopus 로고
    • A statement by the editors of The Lancet
    • Horton R. (2004) A statement by the editors of The Lancet. Lancet 363, 820–821.
    • (2004) Lancet , vol.363 , pp. 820-821
    • Horton, R.1
  • 30
    • 84961317148 scopus 로고    scopus 로고
    • Reproducible Research Practices and Transparency across the Biomedical Literature
    • Iqbal S. A., Wallach J. D., Khoury M. J., Schully S. D. and Ioannidis J. P. A. (2016) Reproducible Research Practices and Transparency across the Biomedical Literature. PLoS Biol. 14, e1002333–1002313.
    • (2016) PLoS Biol. , vol.14 , pp. e1002313-e1002333
    • Iqbal, S.A.1    Wallach, J.D.2    Khoury, M.J.3    Schully, S.D.4    Ioannidis, J.P.A.5
  • 31
    • 84928385276 scopus 로고    scopus 로고
    • Autism occurrence by MMR vaccine status among US children with older siblings with and without autism
    • Jain A., Marshall J., Buikema A., Bancroft T., Kelly J. P. and Newschaffer C. J. (2015) Autism occurrence by MMR vaccine status among US children with older siblings with and without autism. JAMA 313, 1534–1540.
    • (2015) JAMA , vol.313 , pp. 1534-1540
    • Jain, A.1    Marshall, J.2    Buikema, A.3    Bancroft, T.4    Kelly, J.P.5    Newschaffer, C.J.6
  • 32
    • 84929454086 scopus 로고    scopus 로고
    • Thrombectomy within 8 hours after symptom onset in ischemic stroke
    • Jovin T. G., Chamorro A., Cobo E. et al. (2015) Thrombectomy within 8 hours after symptom onset in ischemic stroke. N. Engl. J. Med. 372, 2296–2306.
    • (2015) N. Engl. J. Med. , vol.372 , pp. 2296-2306
    • Jovin, T.G.1    Chamorro, A.2    Cobo, E.3
  • 33
    • 77953028624 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form
    • Kerman A., Liu H.-N., Croul S., Bilbao J., Rogaeva E., Zinman L., Robertson J. and Chakrabartty A. (2010) Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form. Acta Neuropathol. 119, 335–344.
    • (2010) Acta Neuropathol. , vol.119 , pp. 335-344
    • Kerman, A.1    Liu, H.-N.2    Croul, S.3    Bilbao, J.4    Rogaeva, E.5    Zinman, L.6    Robertson, J.7    Chakrabartty, A.8
  • 34
    • 85041813459 scopus 로고    scopus 로고
    • Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research
    • Kilkenny C., Browne W. J., Cuthill I. C., Emerson M. and Altman D. G. (2010) Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol. 8, e1000412.
    • (2010) PLoS Biol. , vol.8
    • Kilkenny, C.1    Browne, W.J.2    Cuthill, I.C.3    Emerson, M.4    Altman, D.G.5
  • 35
    • 84867302438 scopus 로고    scopus 로고
    • A call for transparent reporting to optimize the predictive value of preclinical research
    • Landis S. C., Amara S. G., Asadullah K. et al. (2012) A call for transparent reporting to optimize the predictive value of preclinical research. Nature 490, 187–191.
    • (2012) Nature , vol.490 , pp. 187-191
    • Landis, S.C.1    Amara, S.G.2    Asadullah, K.3
  • 36
    • 84960539638 scopus 로고    scopus 로고
    • The next step in translational research: lessons learned from the first preclinical randomized controlled trial
    • Llovera G. and Liesz A. (2016) The next step in translational research: lessons learned from the first preclinical randomized controlled trial. J. Neurochem. 139(Suppl. 2), 271–279.
    • (2016) J. Neurochem. , vol.139 , Issue.2 , pp. 271-279
    • Llovera, G.1    Liesz, A.2
  • 37
    • 84904689427 scopus 로고    scopus 로고
    • Modeling stroke in mice: permanent coagulation of the distal middle cerebral artery
    • Llovera G., Roth S., Plesnila N., Veltkamp R. and Liesz A. (2014) Modeling stroke in mice: permanent coagulation of the distal middle cerebral artery. J. Vis. Exp. (89): e51729. DOI: 10.3791/51729.
    • (2014) J. Vis. Exp. , Issue.89
    • Llovera, G.1    Roth, S.2    Plesnila, N.3    Veltkamp, R.4    Liesz, A.5
  • 38
    • 84938704875 scopus 로고    scopus 로고
    • Results of a preclinical randomized controlled multicenter trial (pRCT): anti-CD49d treatment for acute brain ischemia
    • Llovera G., Hofmann K., Roth S. et al. (2015) Results of a preclinical randomized controlled multicenter trial (pRCT): anti-CD49d treatment for acute brain ischemia. Sci. Transl. Med. 7, 299ra121.
    • (2015) Sci. Transl. Med. , vol.7 , pp. 299ra121
    • Llovera, G.1    Hofmann, K.2    Roth, S.3
  • 39
    • 77649285022 scopus 로고    scopus 로고
    • Guidelines for preclinical animal research in ALS/MND: a consensus meeting
    • Ludolph A. C., Bendotti C., Blaugrund E. et al. (2010) Guidelines for preclinical animal research in ALS/MND: a consensus meeting. Amyotrophic Lateral Sclerosis 11, 38–45.
    • (2010) Amyotrophic Lateral Sclerosis , vol.11 , pp. 38-45
    • Ludolph, A.C.1    Bendotti, C.2    Blaugrund, E.3
  • 40
    • 34249946466 scopus 로고    scopus 로고
    • Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
    • Mackenzie I. R. A., Bigio E. H., Ince P. G. et al. (2007) Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann. Neurol. 61, 427–434.
    • (2007) Ann. Neurol. , vol.61 , pp. 427-434
    • Mackenzie, I.R.A.1    Bigio, E.H.2    Ince, P.G.3
  • 42
    • 77957245642 scopus 로고    scopus 로고
    • Genetic mouse models of Parkinson's disease The state of the art
    • Magen I. and Chesselet M. F. (2010) Genetic mouse models of Parkinson's disease The state of the art. Prog. Brain Res. 184, 53–87.
    • (2010) Prog. Brain Res. , vol.184 , pp. 53-87
    • Magen, I.1    Chesselet, M.F.2
  • 43
    • 84871022718 scopus 로고    scopus 로고
    • Cell-line authentication: end the scandal of false cell lines
    • Masters J. R. (2012) Cell-line authentication: end the scandal of false cell lines. Nature 492, 186.
    • (2012) Nature , vol.492 , pp. 186
    • Masters, J.R.1
  • 45
    • 12144290507 scopus 로고    scopus 로고
    • Retraction of an interpretation
    • Murch S. H., Anthony A., Casson D. H. et al. (2004) Retraction of an interpretation. The Lancet 363, 750–751.
    • (2004) The Lancet , vol.363 , pp. 750-751
    • Murch, S.H.1    Anthony, A.2    Casson, D.H.3
  • 46
    • 77958591504 scopus 로고    scopus 로고
    • Pre-clinical systematic review
    • Murphy S. P. and Murphy A. N. (2010) Pre-clinical systematic review. J. Neurochem. 115, 805.
    • (2010) J. Neurochem. , vol.115 , pp. 805
    • Murphy, S.P.1    Murphy, A.N.2
  • 47
    • 80052226783 scopus 로고    scopus 로고
    • Erroneous analyses of interactions in neuroscience: a problem of significance
    • Nieuwenhuis S., Forstmann B. U. and Wagenmakers E.-J. (2011) Erroneous analyses of interactions in neuroscience: a problem of significance. Nature Publishing Group 14, 1105–1107.
    • (2011) Nature Publishing Group , vol.14 , pp. 1105-1107
    • Nieuwenhuis, S.1    Forstmann, B.U.2    Wagenmakers, E.-J.3
  • 49
    • 84897434559 scopus 로고    scopus 로고
    • Bidirectional developmental potential in reprogrammed cells with acquired pluripotency
    • Obokata H., Sasai Y., Niwa H. et al. (2014a) Bidirectional developmental potential in reprogrammed cells with acquired pluripotency. Nature 505, 676–680.
    • (2014) Nature , vol.505 , pp. 676-680
    • Obokata, H.1    Sasai, Y.2    Niwa, H.3
  • 50
    • 84903742665 scopus 로고    scopus 로고
    • Retraction: bidirectional developmental potential in reprogrammed cells with acquired pluripotency
    • Obokata H., Sasai Y., Niwa H. et al. (2014b) Retraction: bidirectional developmental potential in reprogrammed cells with acquired pluripotency. Nature 511, 112.
    • (2014) Nature , vol.511 , pp. 112
    • Obokata, H.1    Sasai, Y.2    Niwa, H.3
  • 51
    • 84963594931 scopus 로고    scopus 로고
    • ɑ-Synuclein strains and the variable pathologies of synucleinopathies
    • Peelaerts W. and Baekelandt V. (2016) ɑ-Synuclein strains and the variable pathologies of synucleinopathies. J. Neurochem. 139 (Suppl. 1), 256–274.
    • (2016) J. Neurochem. , vol.139 , pp. 256-274
    • Peelaerts, W.1    Baekelandt, V.2
  • 52
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen D. R., Siddique T., Patterson D. et al. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59–62.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3
  • 53
    • 84930814840 scopus 로고    scopus 로고
    • Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke
    • Saver J. L., Goyal M., Bonafe A. et al. (2015) Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N. Engl. J. Med. 372, 2285–2295.
    • (2015) N. Engl. J. Med. , vol.372 , pp. 2285-2295
    • Saver, J.L.1    Goyal, M.2    Bonafe, A.3
  • 54
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D., Barbour R., Dunn W. et al. (1999) Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400, 173–177.
    • (1999) Nature , vol.400 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3
  • 55
    • 84879948774 scopus 로고    scopus 로고
    • Epidemiology of subacute sclerosing panencephalitis (SSPE) in Germany from 2003 to 2009: a risk estimation
    • Schonberger K., Ludwig M. S., Wildner M. and Weissbrich B. (2013) Epidemiology of subacute sclerosing panencephalitis (SSPE) in Germany from 2003 to 2009: a risk estimation. PLoS ONE 8, e68909.
    • (2013) PLoS ONE , vol.8
    • Schonberger, K.1    Ludwig, M.S.2    Wildner, M.3    Weissbrich, B.4
  • 56
    • 39349107014 scopus 로고    scopus 로고
    • Design, power, and interpretation of studies in the standard murine model of ALS
    • Scott S., Kranz J. E., Cole J. et al. (2009) Design, power, and interpretation of studies in the standard murine model of ALS. Amyotrophic Lateral Sclerosis 9, 4–15.
    • (2009) Amyotrophic Lateral Sclerosis , vol.9 , pp. 4-15
    • Scott, S.1    Kranz, J.E.2    Cole, J.3
  • 57
    • 84985896386 scopus 로고    scopus 로고
    • The antibody aducanumab reduces Aβ plaques in Alzheimer's disease
    • Sevigny J., Chiao P., Bussière T. et al. (2016) The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature 537, 50–56.
    • (2016) Nature , vol.537 , pp. 50-56
    • Sevigny, J.1    Chiao, P.2    Bussière, T.3
  • 58
    • 84901636483 scopus 로고    scopus 로고
    • Vaccines are not associated with autism: an evidence-based meta-analysis of case-control and cohort studies
    • Taylor L. E., Swerdfeger A. L. and Eslick G. D. (2014) Vaccines are not associated with autism: an evidence-based meta-analysis of case-control and cohort studies. Vaccine 32, 3623–3629.
    • (2014) Vaccine , vol.32 , pp. 3623-3629
    • Taylor, L.E.1    Swerdfeger, A.L.2    Eslick, G.D.3
  • 59
    • 85053216755 scopus 로고    scopus 로고
    • RetractionöIleal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
    • The Editors of the Lancet. (2010) RetractionöIleal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. The Lancet, 375, 445.
    • (2010) The Lancet , vol.375 , pp. 445
  • 60
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group (1995) Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med. 333, 1581–1587.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1581-1587
  • 61
    • 84875713751 scopus 로고    scopus 로고
    • Mandated data archiving greatly improves access to research data
    • Vines T. H., Andrew R. L., Bock D. G. et al. (2013) Mandated data archiving greatly improves access to research data. FASEB J. 27, 1304–1308.
    • (2013) FASEB J. , vol.27 , pp. 1304-1308
    • Vines, T.H.1    Andrew, R.L.2    Bock, D.G.3
  • 62
    • 85027934032 scopus 로고    scopus 로고
    • How can rAAV-α -synuclein and the fibril a-synuclein `models advance our understanding of Parkinson’s disease?
    • Volpicelli-Daley L. A., Kirik D., Stoyka L. E., Standaert D. G. and Harms A. S. (2016) How can rAAV-α -synuclein and the fibril a-synuclein `models advance our understanding of Parkinson’s disease? J. Neurochem. 139 (Suppl. 1), 131–155.
    • (2016) J. Neurochem. , vol.139 , pp. 131-155
    • Volpicelli-Daley, L.A.1    Kirik, D.2    Stoyka, L.E.3    Standaert, D.G.4    Harms, A.S.5
  • 63
    • 77958610176 scopus 로고    scopus 로고
    • Administration of thiazolidinediones for neuroprotection in ischemic stroke: a pre-clinical systematic review
    • White A. T. and Murphy A. N. (2010) Administration of thiazolidinediones for neuroprotection in ischemic stroke: a pre-clinical systematic review. J. Neurochem. 115, 845–853.
    • (2010) J. Neurochem. , vol.115 , pp. 845-853
    • White, A.T.1    Murphy, A.N.2
  • 64
    • 84928389546 scopus 로고    scopus 로고
    • A resource for cell line authentication, annotation and quality control
    • Yu M., Selvaraj S. K., Liang-Chu M. M. Y. et al. (2015) A resource for cell line authentication, annotation and quality control. Nature 520, 307–311.
    • (2015) Nature , vol.520 , pp. 307-311
    • Yu, M.1    Selvaraj, S.K.2    Liang-Chu, M.M.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.