메뉴 건너뛰기




Volumn 18, Issue 11, 2016, Pages 1422-1434

Expanded and armed natural killer cells for cancer treatment

Author keywords

cell therapy; chimeric antigen receptors; immunotherapy; NK cells; NKG2D

Indexed keywords

ANTIBODY; CHIMERIC ANTIGEN RECEPTOR; CYTOKINE; MESSENGER RNA;

EID: 84993969535     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2016.06.013     Document Type: Review
Times cited : (63)

References (92)
  • 1
    • 84951310757 scopus 로고    scopus 로고
    • NK cells and cancer: you can teach innate cells new tricks
    • [1] Morvan, M.G., Lanier, L.L., NK cells and cancer: you can teach innate cells new tricks. Nat Rev Cancer 16:1 (2015), 7–19.
    • (2015) Nat Rev Cancer , vol.16 , Issue.1 , pp. 7-19
    • Morvan, M.G.1    Lanier, L.L.2
  • 2
    • 78650970845 scopus 로고    scopus 로고
    • Innate or adaptive immunity? The example of natural killer cells
    • [2] Vivier, E., Raulet, D.H., Moretta, A., Caligiuri, M.A., Zitvogel, L., Lanier, L.L., et al. Innate or adaptive immunity? The example of natural killer cells. Science 331:6013 (2011), 44–49.
    • (2011) Science , vol.331 , Issue.6013 , pp. 44-49
    • Vivier, E.1    Raulet, D.H.2    Moretta, A.3    Caligiuri, M.A.4    Zitvogel, L.5    Lanier, L.L.6
  • 3
    • 84875469893 scopus 로고    scopus 로고
    • A chimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells
    • [3] Chang, Y.H., Connolly, J., Shimasaki, N., Mimura, K., Kono, K., Campana, D., A chimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells. Cancer Res 73:6 (2013), 1777–1786.
    • (2013) Cancer Res , vol.73 , Issue.6 , pp. 1777-1786
    • Chang, Y.H.1    Connolly, J.2    Shimasaki, N.3    Mimura, K.4    Kono, K.5    Campana, D.6
  • 4
    • 50249184550 scopus 로고    scopus 로고
    • Formation and function of the lytic NK-cell immunological synapse
    • [4] Orange, J.S., Formation and function of the lytic NK-cell immunological synapse. Nat Rev Immunol 8:9 (2008), 713–725.
    • (2008) Nat Rev Immunol , vol.8 , Issue.9 , pp. 713-725
    • Orange, J.S.1
  • 5
    • 42449102990 scopus 로고    scopus 로고
    • Up on the tightrope: natural killer cell activation and inhibition
    • [5] Lanier, L.L., Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol 9:5 (2008), 495–502.
    • (2008) Nat Immunol , vol.9 , Issue.5 , pp. 495-502
    • Lanier, L.L.1
  • 6
    • 84925743331 scopus 로고    scopus 로고
    • Balancing natural killer cell activation through paired receptors
    • [6] Martinet, L., Smyth, M.J., Balancing natural killer cell activation through paired receptors. Nat Rev Immunol 15:4 (2015), 243–254.
    • (2015) Nat Rev Immunol , vol.15 , Issue.4 , pp. 243-254
    • Martinet, L.1    Smyth, M.J.2
  • 7
    • 33750730609 scopus 로고    scopus 로고
    • Activation and self-tolerance of natural killer cells
    • [7] Gasser, S., Raulet, D.H., Activation and self-tolerance of natural killer cells. Immunol Rev 214 (2006), 130–142.
    • (2006) Immunol Rev , vol.214 , pp. 130-142
    • Gasser, S.1    Raulet, D.H.2
  • 8
    • 78049427830 scopus 로고    scopus 로고
    • Tumor antigen-targeted, monoclonal antibody-based immunotherapy: clinical response, cellular immunity, and immunoescape
    • [8] Ferris, R.L., Jaffee, E.M., Ferrone, S., Tumor antigen-targeted, monoclonal antibody-based immunotherapy: clinical response, cellular immunity, and immunoescape. J Clin Oncol 28:28 (2010), 4390–4399.
    • (2010) J Clin Oncol , vol.28 , Issue.28 , pp. 4390-4399
    • Ferris, R.L.1    Jaffee, E.M.2    Ferrone, S.3
  • 9
    • 0030728995 scopus 로고    scopus 로고
    • Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations
    • [9] Comans-Bitter, W.M., de Groot, R., van den Beemd, R., Neijens, H.J., Hop, W.C., Groeneveld, K., et al. Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations. J Pediatr 130:3 (1997), 388–393.
    • (1997) J Pediatr , vol.130 , Issue.3 , pp. 388-393
    • Comans-Bitter, W.M.1    de Groot, R.2    van den Beemd, R.3    Neijens, H.J.4    Hop, W.C.5    Groeneveld, K.6
  • 10
    • 84897965451 scopus 로고    scopus 로고
    • Clinical utility of natural killer cells in cancer therapy and transplantation
    • [10] Knorr, D.A., Bachanova, V., Verneris, M.R., Miller, J.S., Clinical utility of natural killer cells in cancer therapy and transplantation. Semin Immunol 26:2 (2014), 161–172.
    • (2014) Semin Immunol , vol.26 , Issue.2 , pp. 161-172
    • Knorr, D.A.1    Bachanova, V.2    Verneris, M.R.3    Miller, J.S.4
  • 11
    • 23644458333 scopus 로고    scopus 로고
    • Licensing of natural killer cells by host major histocompatibility complex class I molecules
    • [11] Kim, S., Poursine-Laurent, J., Truscott, S.M., Lybarger, L., Song, Y.J., Yang, L., et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436:7051 (2005), 709–713.
    • (2005) Nature , vol.436 , Issue.7051 , pp. 709-713
    • Kim, S.1    Poursine-Laurent, J.2    Truscott, S.M.3    Lybarger, L.4    Song, Y.J.5    Yang, L.6
  • 12
    • 18844365992 scopus 로고    scopus 로고
    • A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
    • [12] Fernandez, N.C., Treiner, E., Vance, R.E., Jamieson, A.M., Lemieux, S., Raulet, D.H., A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 105:11 (2005), 4416–4423.
    • (2005) Blood , vol.105 , Issue.11 , pp. 4416-4423
    • Fernandez, N.C.1    Treiner, E.2    Vance, R.E.3    Jamieson, A.M.4    Lemieux, S.5    Raulet, D.H.6
  • 13
    • 33745567831 scopus 로고    scopus 로고
    • Self-tolerance of natural killer cells
    • [13] Raulet, D.H., Vance, R.E., Self-tolerance of natural killer cells. Nat Rev Immunol 6:7 (2006), 520–531.
    • (2006) Nat Rev Immunol , vol.6 , Issue.7 , pp. 520-531
    • Raulet, D.H.1    Vance, R.E.2
  • 14
    • 79960914933 scopus 로고    scopus 로고
    • Unifying concepts of MHC-dependent natural killer cell education
    • [14] Elliott, J.M., Yokoyama, W.M., Unifying concepts of MHC-dependent natural killer cell education. Trends Immunol 32:8 (2011), 364–372.
    • (2011) Trends Immunol , vol.32 , Issue.8 , pp. 364-372
    • Elliott, J.M.1    Yokoyama, W.M.2
  • 15
    • 34547109885 scopus 로고    scopus 로고
    • A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature
    • [15] Cooley, S., Xiao, F., Pitt, M., Gleason, M., McCullar, V., Bergemann, T.L., et al. A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature. Blood 110:2 (2007), 578–586.
    • (2007) Blood , vol.110 , Issue.2 , pp. 578-586
    • Cooley, S.1    Xiao, F.2    Pitt, M.3    Gleason, M.4    McCullar, V.5    Bergemann, T.L.6
  • 16
    • 22044456688 scopus 로고    scopus 로고
    • Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
    • [16] Imai, C., Iwamoto, S., Campana, D., Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells. Blood 106 (2005), 376–383.
    • (2005) Blood , vol.106 , pp. 376-383
    • Imai, C.1    Iwamoto, S.2    Campana, D.3
  • 17
    • 84938493857 scopus 로고    scopus 로고
    • NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
    • [17] Wang, W., Erbe, A.K., Hank, J.A., Morris, Z.S., Sondel, P.M., NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy. Front Immunol, 6, 2015, 368.
    • (2015) Front Immunol , vol.6 , pp. 368
    • Wang, W.1    Erbe, A.K.2    Hank, J.A.3    Morris, Z.S.4    Sondel, P.M.5
  • 18
    • 0022589079 scopus 로고
    • The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes
    • [18] Lanier, L.L., Le, A.M., Civin, C.I., Loken, M.R., Phillips, J.H., The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol 136:12 (1986), 4480–4486.
    • (1986) J Immunol , vol.136 , Issue.12 , pp. 4480-4486
    • Lanier, L.L.1    Le, A.M.2    Civin, C.I.3    Loken, M.R.4    Phillips, J.H.5
  • 19
    • 0024329022 scopus 로고
    • Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule
    • [19] Lanier, L.L., Testi, R., Bindl, J., Phillips, J.H., Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. J Exp Med 169:6 (1989), 2233–2238.
    • (1989) J Exp Med , vol.169 , Issue.6 , pp. 2233-2238
    • Lanier, L.L.1    Testi, R.2    Bindl, J.3    Phillips, J.H.4
  • 20
    • 79958118266 scopus 로고    scopus 로고
    • Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors
    • [20] Delahaye, N.F., Rusakiewicz, S., Martins, I., Menard, C., Roux, S., Lyonnet, L., et al. Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med 17:6 (2011), 700–707.
    • (2011) Nat Med , vol.17 , Issue.6 , pp. 700-707
    • Delahaye, N.F.1    Rusakiewicz, S.2    Martins, I.3    Menard, C.4    Roux, S.5    Lyonnet, L.6
  • 21
    • 84941777829 scopus 로고    scopus 로고
    • Natural killer cell mediated immunosurveillance of pediatric neuroblastoma
    • [21] Semeraro, M., Rusakiewicz, S., Zitvogel, L., Kroemer, G., Natural killer cell mediated immunosurveillance of pediatric neuroblastoma. Oncoimmunology, 4(11), 2015, e1042202.
    • (2015) Oncoimmunology , vol.4 , Issue.11 , pp. e1042202
    • Semeraro, M.1    Rusakiewicz, S.2    Zitvogel, L.3    Kroemer, G.4
  • 22
    • 0242302582 scopus 로고    scopus 로고
    • NK cells and the tumour microenvironment: implications for NK-cell function and anti-tumour activity
    • [22] Albertsson, P.A., Basse, P.H., Hokland, M., Goldfarb, R.H., Nagelkerke, J.F., Nannmark, U., et al. NK cells and the tumour microenvironment: implications for NK-cell function and anti-tumour activity. Trends Immunol 24:11 (2003), 603–609.
    • (2003) Trends Immunol , vol.24 , Issue.11 , pp. 603-609
    • Albertsson, P.A.1    Basse, P.H.2    Hokland, M.3    Goldfarb, R.H.4    Nagelkerke, J.F.5    Nannmark, U.6
  • 23
    • 0037126310 scopus 로고    scopus 로고
    • Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • [23] Groh, V., Wu, J., Yee, C., Spies, T., Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419:6908 (2002), 734–738.
    • (2002) Nature , vol.419 , Issue.6908 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 24
    • 0037108517 scopus 로고    scopus 로고
    • Cutting edge: down-regulation of MICA on human tumors by proteolytic shedding
    • [24] Salih, H.R., Rammensee, H.G., Steinle, A., Cutting edge: down-regulation of MICA on human tumors by proteolytic shedding. J Immunol 169:8 (2002), 4098–4102.
    • (2002) J Immunol , vol.169 , Issue.8 , pp. 4098-4102
    • Salih, H.R.1    Rammensee, H.G.2    Steinle, A.3
  • 25
    • 84907227971 scopus 로고    scopus 로고
    • Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients
    • [25] Crane, C.A., Austgen, K., Haberthur, K., Hofmann, C., Moyes, K.W., Avanesyan, L., et al. Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients. Proc Natl Acad Sci USA 111:35 (2014), 12823–12828.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.35 , pp. 12823-12828
    • Crane, C.A.1    Austgen, K.2    Haberthur, K.3    Hofmann, C.4    Moyes, K.W.5    Avanesyan, L.6
  • 26
    • 0034782592 scopus 로고    scopus 로고
    • Synergistic effect of IFN-gamma and human cytomegalovirus protein UL40 in the HLA-E-dependent protection from NK cell-mediated cytotoxicity
    • [26] Cerboni, C., Mousavi-Jazi, M., Wakiguchi, H., Carbone, E., Karre, K., Soderstrom, K., Synergistic effect of IFN-gamma and human cytomegalovirus protein UL40 in the HLA-E-dependent protection from NK cell-mediated cytotoxicity. Eur J Immunol 31:10 (2001), 2926–2935.
    • (2001) Eur J Immunol , vol.31 , Issue.10 , pp. 2926-2935
    • Cerboni, C.1    Mousavi-Jazi, M.2    Wakiguchi, H.3    Carbone, E.4    Karre, K.5    Soderstrom, K.6
  • 27
    • 0036855636 scopus 로고    scopus 로고
    • IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism
    • [27] Malmberg, K.J., Levitsky, V., Norell, H., de Matos, C.T., Carlsten, M., Schedvins, K., et al. IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism. J Clin Invest 110:10 (2002), 1515–1523.
    • (2002) J Clin Invest , vol.110 , Issue.10 , pp. 1515-1523
    • Malmberg, K.J.1    Levitsky, V.2    Norell, H.3    de Matos, C.T.4    Carlsten, M.5    Schedvins, K.6
  • 28
    • 0036183321 scopus 로고    scopus 로고
    • Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells
    • [28] Borrego, F., Kabat, J., Kim, D.K., Lieto, L., Maasho, K., Pena, J., et al. Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. Mol Immunol 38:9 (2002), 637–660.
    • (2002) Mol Immunol , vol.38 , Issue.9 , pp. 637-660
    • Borrego, F.1    Kabat, J.2    Kim, D.K.3    Lieto, L.4    Maasho, K.5    Pena, J.6
  • 29
    • 80052434130 scopus 로고    scopus 로고
    • Human tumour immune evasion via TGF-beta blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity
    • [29] Wilson, E.B., El-Jawhari, J.J., Neilson, A.L., Hall, G.D., Melcher, A.A., Meade, J.L., et al. Human tumour immune evasion via TGF-beta blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity. PLoS ONE, 6(9), 2011, e22842.
    • (2011) PLoS ONE , vol.6 , Issue.9 , pp. e22842
    • Wilson, E.B.1    El-Jawhari, J.J.2    Neilson, A.L.3    Hall, G.D.4    Melcher, A.A.5    Meade, J.L.6
  • 30
    • 84959134520 scopus 로고    scopus 로고
    • TGF-beta inhibits the activation and functions of NK cells by repressing the mTOR pathway
    • [30] Viel, S., Marcais, A., Guimaraes, F.S., Loftus, R., Rabilloud, J., Grau, M., et al. TGF-beta inhibits the activation and functions of NK cells by repressing the mTOR pathway. Sci Signal, 9(415), 2016, ra19.
    • (2016) Sci Signal , vol.9 , Issue.415 , pp. ra19
    • Viel, S.1    Marcais, A.2    Guimaraes, F.S.3    Loftus, R.4    Rabilloud, J.5    Grau, M.6
  • 31
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • [31] Ruggeri, L., Capanni, M., Urbani, E., Perruccio, K., Shlomchik, W.D., Tosti, A., et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295:5562 (2002), 2097–2100.
    • (2002) Science , vol.295 , Issue.5562 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3    Perruccio, K.4    Shlomchik, W.D.5    Tosti, A.6
  • 32
    • 10744230735 scopus 로고    scopus 로고
    • Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors
    • [32] Giebel, S., Locatelli, F., Lamparelli, T., Velardi, A., Davies, S., Frumento, G., et al. Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors. Blood 102:3 (2003), 814–819.
    • (2003) Blood , vol.102 , Issue.3 , pp. 814-819
    • Giebel, S.1    Locatelli, F.2    Lamparelli, T.3    Velardi, A.4    Davies, S.5    Frumento, G.6
  • 33
    • 0347994940 scopus 로고    scopus 로고
    • Determinants of antileukemia effects of allogeneic NK cells
    • [33] Leung, W., Iyengar, R., Turner, V., Lang, P., Bader, P., Conn, P., et al. Determinants of antileukemia effects of allogeneic NK cells. J Immunol 172:1 (2004), 644–650.
    • (2004) J Immunol , vol.172 , Issue.1 , pp. 644-650
    • Leung, W.1    Iyengar, R.2    Turner, V.3    Lang, P.4    Bader, P.5    Conn, P.6
  • 34
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes
    • [34] Hsu, K.C., Keever-Taylor, C.A., Wilton, A., Pinto, C., Heller, G., Arkun, K., et al. Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes. Blood 105:12 (2005), 4878–4884.
    • (2005) Blood , vol.105 , Issue.12 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3    Pinto, C.4    Heller, G.5    Arkun, K.6
  • 35
    • 77957734984 scopus 로고    scopus 로고
    • Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
    • [35] Cooley, S., Weisdorf, D.J., Guethlein, L.A., Klein, J.P., Wang, T., Le, C.T., et al. Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood 116:14 (2010), 2411–2419.
    • (2010) Blood , vol.116 , Issue.14 , pp. 2411-2419
    • Cooley, S.1    Weisdorf, D.J.2    Guethlein, L.A.3    Klein, J.P.4    Wang, T.5    Le, C.T.6
  • 36
    • 84905970560 scopus 로고    scopus 로고
    • Therapeutic applications: natural killer cells in the clinic
    • [36] Miller, J.S., Therapeutic applications: natural killer cells in the clinic. Hematology Am Soc Hematol Educ Program 2013 (2013), 247–253.
    • (2013) Hematology Am Soc Hematol Educ Program , vol.2013 , pp. 247-253
    • Miller, J.S.1
  • 37
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in cancer patients
    • [37] Miller, J.S., Soignier, Y., Panoskaltsis-Mortari, A., McNearney, S.A., Yun, G.H., Fautsch, S.K., et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in cancer patients. Blood 105 (2005), 3051–3057.
    • (2005) Blood , vol.105 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3    McNearney, S.A.4    Yun, G.H.5    Fautsch, S.K.6
  • 38
    • 0346339806 scopus 로고    scopus 로고
    • Purification of human natural killer cells using a clinical-scale immunomagnetic method
    • [38] Iyengar, R., Handgretinger, R., Babarin-Dorner, A., Leimig, T., Otto, M., Geiger, T.L., et al. Purification of human natural killer cells using a clinical-scale immunomagnetic method. Cytotherapy 5:6 (2003), 479–484.
    • (2003) Cytotherapy , vol.5 , Issue.6 , pp. 479-484
    • Iyengar, R.1    Handgretinger, R.2    Babarin-Dorner, A.3    Leimig, T.4    Otto, M.5    Geiger, T.L.6
  • 39
    • 78149253287 scopus 로고    scopus 로고
    • Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy
    • [39] Lee, D.A., Verneris, M.R., Campana, D., Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy. Methods Mol Biol 651 (2010), 61–77.
    • (2010) Methods Mol Biol , vol.651 , pp. 61-77
    • Lee, D.A.1    Verneris, M.R.2    Campana, D.3
  • 40
    • 84927154659 scopus 로고    scopus 로고
    • Enhanced cytotoxic function of natural killer and CD3+CD56+ cells in cord blood after culture
    • [40] Tomchuck, S.L., Leung, W.H., Dallas, M.H., Enhanced cytotoxic function of natural killer and CD3+CD56+ cells in cord blood after culture. Biol Blood Marrow Transplant 21:1 (2015), 39–49.
    • (2015) Biol Blood Marrow Transplant , vol.21 , Issue.1 , pp. 39-49
    • Tomchuck, S.L.1    Leung, W.H.2    Dallas, M.H.3
  • 41
    • 84954209229 scopus 로고    scopus 로고
    • Induced pluripotent stem cell-derived natural killer cells for treatment of ovarian cancer
    • [41] Hermanson, D.L., Bendzick, L., Pribyl, L., McCullar, V., Vogel, R.I., Miller, J.S., et al. Induced pluripotent stem cell-derived natural killer cells for treatment of ovarian cancer. Stem Cells 34:1 (2016), 93–101.
    • (2016) Stem Cells , vol.34 , Issue.1 , pp. 93-101
    • Hermanson, D.L.1    Bendzick, L.2    Pribyl, L.3    McCullar, V.4    Vogel, R.I.5    Miller, J.S.6
  • 42
    • 84878250013 scopus 로고    scopus 로고
    • Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling
    • [42] James, A.M., Hsu, H.T., Dongre, P., Uzel, G., Mace, E.M., Banerjee, P.P., et al. Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling. Blood 121:14 (2013), 2627–2637.
    • (2013) Blood , vol.121 , Issue.14 , pp. 2627-2637
    • James, A.M.1    Hsu, H.T.2    Dongre, P.3    Uzel, G.4    Mace, E.M.5    Banerjee, P.P.6
  • 44
    • 84872225254 scopus 로고    scopus 로고
    • Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors
    • [44] Ni, J., Miller, M., Stojanovic, A., Garbi, N., Cerwenka, A., Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J Exp Med 209:13 (2012), 2351–2365.
    • (2012) J Exp Med , vol.209 , Issue.13 , pp. 2351-2365
    • Ni, J.1    Miller, M.2    Stojanovic, A.3    Garbi, N.4    Cerwenka, A.5
  • 45
    • 0023035619 scopus 로고
    • Induction of proliferation in vitro of resting human natural killer cells: IL 2 induces into cell cycle most peripheral blood NK cells, but only a minor subset of low density T cells
    • [45] London, L., Perussia, B., Trinchieri, G., Induction of proliferation in vitro of resting human natural killer cells: IL 2 induces into cell cycle most peripheral blood NK cells, but only a minor subset of low density T cells. J Immunol 137:12 (1986), 3845–3854.
    • (1986) J Immunol , vol.137 , Issue.12 , pp. 3845-3854
    • London, L.1    Perussia, B.2    Trinchieri, G.3
  • 46
    • 42449160619 scopus 로고    scopus 로고
    • Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components
    • [46] Alici, E., Sutlu, T., Bjorkstrand, B., Gilljam, M., Stellan, B., Nahi, H., et al. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood 111:6 (2008), 3155–3162.
    • (2008) Blood , vol.111 , Issue.6 , pp. 3155-3162
    • Alici, E.1    Sutlu, T.2    Bjorkstrand, B.3    Gilljam, M.4    Stellan, B.5    Nahi, H.6
  • 47
    • 79959241846 scopus 로고    scopus 로고
    • Interleukin (IL)-15 in combination with IL-2, fms-like tyrosine kinase-3 ligand and anti-CD3 significantly enhances umbilical cord blood natural killer (NK) cell and NK-cell subset expansion and NK function
    • [47] Satwani, P., van de Ven, C., Ayello, J., Cairo, D., Simpson, L.L., Baxi, L., et al. Interleukin (IL)-15 in combination with IL-2, fms-like tyrosine kinase-3 ligand and anti-CD3 significantly enhances umbilical cord blood natural killer (NK) cell and NK-cell subset expansion and NK function. Cytotherapy 13:6 (2011), 730–738.
    • (2011) Cytotherapy , vol.13 , Issue.6 , pp. 730-738
    • Satwani, P.1    van de Ven, C.2    Ayello, J.3    Cairo, D.4    Simpson, L.L.5    Baxi, L.6
  • 48
    • 65949111530 scopus 로고    scopus 로고
    • Expansion of highly cytotoxic human natural killer cells for cancer cell therapy
    • [48] Fujisaki, H., Kakuda, H., Shimasaki, N., Imai, C., Ma, J., Lockey, T., et al. Expansion of highly cytotoxic human natural killer cells for cancer cell therapy. Cancer Res 69:9 (2009), 4010–4017.
    • (2009) Cancer Res , vol.69 , Issue.9 , pp. 4010-4017
    • Fujisaki, H.1    Kakuda, H.2    Shimasaki, N.3    Imai, C.4    Ma, J.5    Lockey, T.6
  • 49
    • 68049132603 scopus 로고    scopus 로고
    • Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells
    • [49] Berg, M., Lundqvist, A., McCoy, P. Jr, Samsel, L., Fan, Y., Tawab, A., et al. Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells. Cytotherapy 11:3 (2009), 341–355.
    • (2009) Cytotherapy , vol.11 , Issue.3 , pp. 341-355
    • Berg, M.1    Lundqvist, A.2    McCoy, P.3    Samsel, L.4    Fan, Y.5    Tawab, A.6
  • 50
    • 3042837951 scopus 로고    scopus 로고
    • A Wilms tumor cell line, HFWT, can greatly stimulate proliferation of CD56+ human natural killer cells and their novel precursors in blood mononuclear cells
    • [50] Harada, H., Watanabe, S., Saijo, K., Ishiwata, I., Ohno, T., A Wilms tumor cell line, HFWT, can greatly stimulate proliferation of CD56+ human natural killer cells and their novel precursors in blood mononuclear cells. Exp Hematol 32:7 (2004), 614–621.
    • (2004) Exp Hematol , vol.32 , Issue.7 , pp. 614-621
    • Harada, H.1    Watanabe, S.2    Saijo, K.3    Ishiwata, I.4    Ohno, T.5
  • 51
    • 84936088673 scopus 로고    scopus 로고
    • Two-stage priming of allogeneic natural killer cells for the treatment of patients with acute myeloid leukemia: a phase i trial
    • [51] Kottaridis, P.D., North, J., Tsirogianni, M., Marden, C., Samuel, E.R., Jide-Banwo, S., et al. Two-stage priming of allogeneic natural killer cells for the treatment of patients with acute myeloid leukemia: a phase i trial. PLoS ONE, 10(6), 2015, e0123416.
    • (2015) PLoS ONE , vol.10 , Issue.6 , pp. e0123416
    • Kottaridis, P.D.1    North, J.2    Tsirogianni, M.3    Marden, C.4    Samuel, E.R.5    Jide-Banwo, S.6
  • 52
    • 0021815642 scopus 로고
    • A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562
    • [52] Phillips, J.H., Lanier, L.L., A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562. J Exp Med 161:6 (1985), 1464–1482.
    • (1985) J Exp Med , vol.161 , Issue.6 , pp. 1464-1482
    • Phillips, J.H.1    Lanier, L.L.2
  • 53
    • 11244255868 scopus 로고    scopus 로고
    • Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance
    • [53] Kobayashi, H., Dubois, S., Sato, N., Sabzevari, H., Sakai, Y., Waldmann, T.A., et al. Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance. Blood 105:2 (2005), 721–727.
    • (2005) Blood , vol.105 , Issue.2 , pp. 721-727
    • Kobayashi, H.1    Dubois, S.2    Sato, N.3    Sabzevari, H.4    Sakai, Y.5    Waldmann, T.A.6
  • 54
    • 0032535119 scopus 로고    scopus 로고
    • NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
    • [54] Melero, I., Johnston, J.V., Shufford, W.W., Mittler, R.S., Chen, L., NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol 190:2 (1998), 167–172.
    • (1998) Cell Immunol , vol.190 , Issue.2 , pp. 167-172
    • Melero, I.1    Johnston, J.V.2    Shufford, W.W.3    Mittler, R.S.4    Chen, L.5
  • 56
    • 84866501841 scopus 로고    scopus 로고
    • Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications
    • [56] Lapteva, N., Durett, A.G., Sun, J., Rollins, L.A., Huye, L.L., Fang, J., et al. Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications. Cytotherapy 14:9 (2012), 1131–1143.
    • (2012) Cytotherapy , vol.14 , Issue.9 , pp. 1131-1143
    • Lapteva, N.1    Durett, A.G.2    Sun, J.3    Rollins, L.A.4    Huye, L.L.5    Fang, J.6
  • 57
    • 34247212403 scopus 로고    scopus 로고
    • Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules
    • [57] Suhoski, M.M., Golovina, T.N., Aqui, N.A., Tai, V.C., Varela-Rohena, A., Milone, M.C., et al. Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. Mol Ther 15:5 (2007), 981–988.
    • (2007) Mol Ther , vol.15 , Issue.5 , pp. 981-988
    • Suhoski, M.M.1    Golovina, T.N.2    Aqui, N.A.3    Tai, V.C.4    Varela-Rohena, A.5    Milone, M.C.6
  • 58
    • 79953062729 scopus 로고    scopus 로고
    • Activating signals dominate inhibitory signals in CD137L/IL-15 activated natural killer cells
    • [58] Zhang, H., Cui, Y., Voong, N., Sabatino, M., Stroncek, D.F., Morisot, S., et al. Activating signals dominate inhibitory signals in CD137L/IL-15 activated natural killer cells. J Immunother 34:2 (2011), 187–195.
    • (2011) J Immunother , vol.34 , Issue.2 , pp. 187-195
    • Zhang, H.1    Cui, Y.2    Voong, N.3    Sabatino, M.4    Stroncek, D.F.5    Morisot, S.6
  • 59
    • 84921805688 scopus 로고    scopus 로고
    • Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation
    • [59] Shah, N.N., Baird, K., Delbrook, C.P., Fleisher, T.A., Kohler, M.E., Rampertaap, S., et al. Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation. Blood 125:5 (2015), 784–792.
    • (2015) Blood , vol.125 , Issue.5 , pp. 784-792
    • Shah, N.N.1    Baird, K.2    Delbrook, C.P.3    Fleisher, T.A.4    Kohler, M.E.5    Rampertaap, S.6
  • 60
    • 84862908673 scopus 로고    scopus 로고
    • Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
    • [60] Denman, C.J., Senyukov, V.V., Somanchi, S.S., Phatarpekar, P.V., Kopp, L.M., Johnson, J.L., et al. Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells. PLoS ONE, 7(1), 2012, e30264.
    • (2012) PLoS ONE , vol.7 , Issue.1 , pp. e30264
    • Denman, C.J.1    Senyukov, V.V.2    Somanchi, S.S.3    Phatarpekar, P.V.4    Kopp, L.M.5    Johnson, J.L.6
  • 61
    • 0042194439 scopus 로고    scopus 로고
    • Ex vivo expansion of the highly cytotoxic human natural killer-92 cell-line under current good manufacturing practice conditions for clinical adoptive cellular immunotherapy
    • [61] Tam, Y.K., Martinson, J.A., Doligosa, K., Klingemann, H.G., Ex vivo expansion of the highly cytotoxic human natural killer-92 cell-line under current good manufacturing practice conditions for clinical adoptive cellular immunotherapy. Cytotherapy 5:3 (2003), 259–272.
    • (2003) Cytotherapy , vol.5 , Issue.3 , pp. 259-272
    • Tam, Y.K.1    Martinson, J.A.2    Doligosa, K.3    Klingemann, H.G.4
  • 62
    • 77955119958 scopus 로고    scopus 로고
    • Cytotoxicity of activated natural killer cells against pediatric solid tumors
    • [62] Cho, D., Shook, D.R., Shimasaki, N., Chang, Y.H., Fujisaki, H., Campana, D., Cytotoxicity of activated natural killer cells against pediatric solid tumors. Clin Cancer Res 16:15 (2010), 3901–3909.
    • (2010) Clin Cancer Res , vol.16 , Issue.15 , pp. 3901-3909
    • Cho, D.1    Shook, D.R.2    Shimasaki, N.3    Chang, Y.H.4    Fujisaki, H.5    Campana, D.6
  • 63
    • 84904052770 scopus 로고    scopus 로고
    • Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer
    • [63] Mimura, K., Kamiya, T., Shiraishi, K., Kua, L.F., Shabbir, A., So, J., et al. Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer. Int J Cancer 135:6 (2014), 1390–1398.
    • (2014) Int J Cancer , vol.135 , Issue.6 , pp. 1390-1398
    • Mimura, K.1    Kamiya, T.2    Shiraishi, K.3    Kua, L.F.4    Shabbir, A.5    So, J.6
  • 64
    • 84979771531 scopus 로고    scopus 로고
    • Expanded and activated natural killer cells for immunotherapy of hepatocellular carcinoma
    • [64] Kamiya, T., Chang, Y.H., Campana, D., Expanded and activated natural killer cells for immunotherapy of hepatocellular carcinoma. Cancer Immunol Res 4:7 (2016), 574–581.
    • (2016) Cancer Immunol Res , vol.4 , Issue.7 , pp. 574-581
    • Kamiya, T.1    Chang, Y.H.2    Campana, D.3
  • 65
    • 0032568520 scopus 로고    scopus 로고
    • Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells
    • [65] Ho, E.L., Heusel, J.W., Brown, M.G., Matsumoto, K., Scalzo, A.A., Yokoyama, W.M., Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells. Proc Natl Acad Sci USA 95:11 (1998), 6320–6325.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.11 , pp. 6320-6325
    • Ho, E.L.1    Heusel, J.W.2    Brown, M.G.3    Matsumoto, K.4    Scalzo, A.A.5    Yokoyama, W.M.6
  • 66
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • [66] Bauer, S., Groh, V., Wu, J., Steinle, A., Phillips, J.H., Lanier, L.L., et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285:5428 (1999), 727–729.
    • (1999) Science , vol.285 , Issue.5428 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3    Steinle, A.4    Phillips, J.H.5    Lanier, L.L.6
  • 67
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • [67] Gasser, S., Orsulic, S., Brown, E.J., Raulet, D.H., The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 436:7054 (2005), 1186–1190.
    • (2005) Nature , vol.436 , Issue.7054 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 68
    • 77951683908 scopus 로고    scopus 로고
    • Effect of NKG2D ligand expression on host immune responses
    • [68] Champsaur, M., Lanier, L.L., Effect of NKG2D ligand expression on host immune responses. Immunol Rev 235:1 (2010), 267–285.
    • (2010) Immunol Rev , vol.235 , Issue.1 , pp. 267-285
    • Champsaur, M.1    Lanier, L.L.2
  • 69
    • 0033618624 scopus 로고    scopus 로고
    • An activating immunoreceptor complex formed by NKG2D and DAP10
    • [69] Wu, J., Song, Y., Bakker, A.B., Bauer, S., Spies, T., Lanier, L.L., et al. An activating immunoreceptor complex formed by NKG2D and DAP10. Science 285:5428 (1999), 730–732.
    • (1999) Science , vol.285 , Issue.5428 , pp. 730-732
    • Wu, J.1    Song, Y.2    Bakker, A.B.3    Bauer, S.4    Spies, T.5    Lanier, L.L.6
  • 70
    • 0036915968 scopus 로고    scopus 로고
    • Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
    • [70] Diefenbach, A., Tomasello, E., Lucas, M., Jamieson, A.M., Hsia, J.K., Vivier, E., et al. Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol 3:12 (2002), 1142–1149.
    • (2002) Nat Immunol , vol.3 , Issue.12 , pp. 1142-1149
    • Diefenbach, A.1    Tomasello, E.2    Lucas, M.3    Jamieson, A.M.4    Hsia, J.K.5    Vivier, E.6
  • 71
    • 19644365065 scopus 로고    scopus 로고
    • The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure
    • [71] Garrity, D., Call, M.E., Feng, J., Wucherpfennig, K.W., The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure. Proc Natl Acad Sci USA 102:21 (2005), 7641–7646.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.21 , pp. 7641-7646
    • Garrity, D.1    Call, M.E.2    Feng, J.3    Wucherpfennig, K.W.4
  • 73
    • 0142197631 scopus 로고    scopus 로고
    • Roles of the NKG2D immunoreceptor and its ligands
    • [73] Raulet, D.H., Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 3:10 (2003), 781–790.
    • (2003) Nat Rev Immunol , vol.3 , Issue.10 , pp. 781-790
    • Raulet, D.H.1
  • 74
    • 69249108787 scopus 로고    scopus 로고
    • Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells
    • [74] Romagne, F., Andre, P., Spee, P., Zahn, S., Anfossi, N., Gauthier, L., et al. Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood 114:13 (2009), 2667–2677.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2667-2677
    • Romagne, F.1    Andre, P.2    Spee, P.3    Zahn, S.4    Anfossi, N.5    Gauthier, L.6
  • 75
    • 83455220035 scopus 로고    scopus 로고
    • IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect
    • [75] Benson, D.M. Jr, Bakan, C.E., Zhang, S., Collins, S.M., Liang, J., Srivastava, S., et al. IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect. Blood 118:24 (2011), 6387–6391.
    • (2011) Blood , vol.118 , Issue.24 , pp. 6387-6391
    • Benson, D.M.1    Bakan, C.E.2    Zhang, S.3    Collins, S.M.4    Liang, J.5    Srivastava, S.6
  • 76
    • 84964787439 scopus 로고    scopus 로고
    • Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells
    • [76] Ruggeri, L., Urbani, E., Andre, P., Mancusi, A., Tosti, A., Topini, F., et al. Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells. Haematologica 101:5 (2016), 626–633.
    • (2016) Haematologica , vol.101 , Issue.5 , pp. 626-633
    • Ruggeri, L.1    Urbani, E.2    Andre, P.3    Mancusi, A.4    Tosti, A.5    Topini, F.6
  • 77
    • 84905989882 scopus 로고    scopus 로고
    • Autonomous growth and increased cytotoxicity of natural killer cells expressing membrane-bound interleukin-15
    • [77] Imamura, M., Shook, D., Kamiya, T., Shimasaki, N., Chai, S.M., Coustan-Smith, E., et al. Autonomous growth and increased cytotoxicity of natural killer cells expressing membrane-bound interleukin-15. Blood 124:7 (2014), 1081–1088.
    • (2014) Blood , vol.124 , Issue.7 , pp. 1081-1088
    • Imamura, M.1    Shook, D.2    Kamiya, T.3    Shimasaki, N.4    Chai, S.M.5    Coustan-Smith, E.6
  • 78
    • 77949898005 scopus 로고    scopus 로고
    • NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia
    • [78] Rubnitz, J.E., Inaba, H., Ribeiro, R.C., Pounds, S., Rooney, B., Bell, T., et al. NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia. J Clin Oncol 28:6 (2010), 955–959.
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 955-959
    • Rubnitz, J.E.1    Inaba, H.2    Ribeiro, R.C.3    Pounds, S.4    Rooney, B.5    Bell, T.6
  • 79
    • 84886849781 scopus 로고    scopus 로고
    • Toward eliminating HLA class I expression to generate universal cells from allogeneic donors
    • [79] Torikai, H., Reik, A., Soldner, F., Warren, E.H., Yuen, C., Zhou, Y., et al. Toward eliminating HLA class I expression to generate universal cells from allogeneic donors. Blood 122:8 (2013), 1341–1349.
    • (2013) Blood , vol.122 , Issue.8 , pp. 1341-1349
    • Torikai, H.1    Reik, A.2    Soldner, F.3    Warren, E.H.4    Yuen, C.5    Zhou, Y.6
  • 80
    • 84940718499 scopus 로고    scopus 로고
    • A multidrug-resistant engineered CAR T cell for allogeneic combination immunotherapy
    • [80] Valton, J., Guyot, V., Marechal, A., Filhol, J.M., Juillerat, A., Duclert, A., et al. A multidrug-resistant engineered CAR T cell for allogeneic combination immunotherapy. Mol Ther 23:9 (2015), 1507–1518.
    • (2015) Mol Ther , vol.23 , Issue.9 , pp. 1507-1518
    • Valton, J.1    Guyot, V.2    Marechal, A.3    Filhol, J.M.4    Juillerat, A.5    Duclert, A.6
  • 81
    • 84863915982 scopus 로고    scopus 로고
    • A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies
    • [81] Shimasaki, N., Fujisaki, H., Cho, D., Masselli, M., Lockey, T., Eldridge, P., et al. A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies. Cytotherapy 14:7 (2012), 830–840.
    • (2012) Cytotherapy , vol.14 , Issue.7 , pp. 830-840
    • Shimasaki, N.1    Fujisaki, H.2    Cho, D.3    Masselli, M.4    Lockey, T.5    Eldridge, P.6
  • 82
    • 76749149456 scopus 로고    scopus 로고
    • Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method
    • [82] Li, L., Liu, L.N., Feller, S., Allen, C., Shivakumar, R., Fratantoni, J., et al. Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method. Cancer Gene Ther 17:3 (2010), 147–154.
    • (2010) Cancer Gene Ther , vol.17 , Issue.3 , pp. 147-154
    • Li, L.1    Liu, L.N.2    Feller, S.3    Allen, C.4    Shivakumar, R.5    Fratantoni, J.6
  • 83
    • 84878642671 scopus 로고    scopus 로고
    • Natural killer cell reprogramming with chimeric immune receptors
    • [83] Shimasaki, N., Campana, D., Natural killer cell reprogramming with chimeric immune receptors. Methods Mol Biol 969 (2013), 203–220.
    • (2013) Methods Mol Biol , vol.969 , pp. 203-220
    • Shimasaki, N.1    Campana, D.2
  • 84
    • 56249128626 scopus 로고    scopus 로고
    • Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
    • [84] Kruschinski, A., Moosmann, A., Poschke, I., Norell, H., Chmielewski, M., Seliger, B., et al. Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas. Proc Natl Acad Sci USA 105:45 (2008), 17481–17486.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.45 , pp. 17481-17486
    • Kruschinski, A.1    Moosmann, A.2    Poschke, I.3    Norell, H.4    Chmielewski, M.5    Seliger, B.6
  • 85
    • 68049142423 scopus 로고    scopus 로고
    • 2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells
    • [85] Altvater, B., Landmeier, S., Pscherer, S., Temme, J., Schweer, K., Kailayangiri, S., et al. 2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells. Clin Cancer Res 15:15 (2009), 4857–4866.
    • (2009) Clin Cancer Res , vol.15 , Issue.15 , pp. 4857-4866
    • Altvater, B.1    Landmeier, S.2    Pscherer, S.3    Temme, J.4    Schweer, K.5    Kailayangiri, S.6
  • 86
    • 84881169028 scopus 로고    scopus 로고
    • Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition
    • [86] Wiernik, A., Foley, B., Zhang, B., Verneris, M.R., Warlick, E., Gleason, M.K., et al. Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition. Clin Cancer Res 19:14 (2013), 3844–3855.
    • (2013) Clin Cancer Res , vol.19 , Issue.14 , pp. 3844-3855
    • Wiernik, A.1    Foley, B.2    Zhang, B.3    Verneris, M.R.4    Warlick, E.5    Gleason, M.K.6
  • 87
    • 84877872803 scopus 로고    scopus 로고
    • Heterodimeric bispecific single-chain variable-fragment antibodies against EpCAM and CD16 induce effective antibody-dependent cellular cytotoxicity against human carcinoma cells
    • [87] Vallera, D.A., Zhang, B., Gleason, M.K., Oh, S., Weiner, L.M., Kaufman, D.S., et al. Heterodimeric bispecific single-chain variable-fragment antibodies against EpCAM and CD16 induce effective antibody-dependent cellular cytotoxicity against human carcinoma cells. Cancer Biother Radiopharm 28:4 (2013), 274–282.
    • (2013) Cancer Biother Radiopharm , vol.28 , Issue.4 , pp. 274-282
    • Vallera, D.A.1    Zhang, B.2    Gleason, M.K.3    Oh, S.4    Weiner, L.M.5    Kaufman, D.S.6
  • 88
    • 84917708726 scopus 로고    scopus 로고
    • Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients
    • [88] Szmania, S., Lapteva, N., Garg, T., Greenway, A., Lingo, J., Nair, B., et al. Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients. J Immunother 38:1 (2015), 24–36.
    • (2015) J Immunother , vol.38 , Issue.1 , pp. 24-36
    • Szmania, S.1    Lapteva, N.2    Garg, T.3    Greenway, A.4    Lingo, J.5    Nair, B.6
  • 89
    • 84865841809 scopus 로고    scopus 로고
    • Highly activated and expanded natural killer cells for multiple myeloma immunotherapy
    • [89] Garg, T.K., Szmania, S.M., Khan, J.A., Hoering, A., Malbrough, P.A., Moreno-Bost, A., et al. Highly activated and expanded natural killer cells for multiple myeloma immunotherapy. Haematologica 97:9 (2012), 1348–1356.
    • (2012) Haematologica , vol.97 , Issue.9 , pp. 1348-1356
    • Garg, T.K.1    Szmania, S.M.2    Khan, J.A.3    Hoering, A.4    Malbrough, P.A.5    Moreno-Bost, A.6
  • 90
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • [90] Dudley, M.E., Wunderlich, J.R., Robbins, P.F., Yang, J.C., Hwu, P., Schwartzentruber, D.J., et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298:5594 (2002), 850–854.
    • (2002) Science , vol.298 , Issue.5594 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3    Yang, J.C.4    Hwu, P.5    Schwartzentruber, D.J.6
  • 91
    • 70349482341 scopus 로고    scopus 로고
    • Click-iT assay with improved DNA distribution histograms
    • [91] Hamelik, R.M., Krishan, A., Click-iT assay with improved DNA distribution histograms. Cytometry A 75:10 (2009), 862–865.
    • (2009) Cytometry A , vol.75 , Issue.10 , pp. 862-865
    • Hamelik, R.M.1    Krishan, A.2
  • 92
    • 0033011520 scopus 로고    scopus 로고
    • Distinct clinical and laboratory activity of two recombinant interleukin-2 preparations
    • [92] Hank, J.A., Surfus, J., Gan, J., Albertini, M., Lindstrom, M., Schiller, J.H., et al. Distinct clinical and laboratory activity of two recombinant interleukin-2 preparations. Clin Cancer Res 5:2 (1999), 281–289.
    • (1999) Clin Cancer Res , vol.5 , Issue.2 , pp. 281-289
    • Hank, J.A.1    Surfus, J.2    Gan, J.3    Albertini, M.4    Lindstrom, M.5    Schiller, J.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.