The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors

ACS Nano

Volumn 10, Issue 10, 2016, Pages 9243-9258

  Miao, Lei ^a   Newby, Jay M ^b   Lin, C Michael ^a   Zhang, Lu ^a   Xu, Feifei ^b   Kim, William Y ^b   Forest, M Gregory ^b   Lai, Samuel K ^a   Milowsky, Matthew I ^c   Wobker, Sara E ^c   Huang, Leaf ^a  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

binding site barrier; desmoplastic tumor; nanoparticle; stroma vessel type tumor; tumor associated fibroblast

Indexed keywords

BINDING ENERGY; BINS; CELL CULTURE; CELLS; CYTOLOGY; FIBROBLASTS; NANOPARTICLES; PARTICLE SIZE; TUMORS;

BINDING AFFINITIES; BINDING BEHAVIORS; EXTRACELLULAR MATRICES; INTRAVENOUS INJECTIONS; NANOPARTICLE (NPS); PHYSICAL BARRIERS; RECEPTOR PROTEINS; THERAPEUTIC OUTCOMES;

BLOOD VESSELS;

EID: 84993940075     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.6b02776     Document Type: Article

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