-
1
-
-
61849153021
-
Impact of nanotechnology on drug delivery
-
Farokhzad OC, Langer R. Impact of nanotechnology on drug delivery. ACS Nano 2009;3:16-20.
-
(2009)
ACS Nano
, vol.3
, pp. 16-20
-
-
Farokhzad, O.C.1
Langer, R.2
-
2
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2007;2:751-60.
-
(2007)
Nat Nanotechnol
, vol.2
, pp. 751-760
-
-
Peer, D.1
Karp, J.M.2
Hong, S.3
Farokhzad, O.C.4
Margalit, R.5
Langer, R.6
-
3
-
-
33947525625
-
The EPR effect and polymeric drugs: A paradigm shift for cancer chemotherapy in the 21st century
-
New York: Springer
-
Maeda H, Greish K, Fang J. The EPR effect and polymeric drugs: a paradigm shift for cancer chemotherapy in the 21st century. In: Polymer Therapeutics II. New York: Springer; 2006. p. 103-21.
-
(2006)
Polymer Therapeutics II
, pp. 103-121
-
-
Maeda, H.1
Greish, K.2
Fang, J.3
-
4
-
-
43549100662
-
Concept and clinical evaluation of carrier-mediated anticancer agents
-
Zamboni WC. Concept and clinical evaluation of carrier-mediated anticancer agents. Oncologist 2008;13:248-60.
-
(2008)
Oncologist
, vol.13
, pp. 248-260
-
-
Zamboni, W.C.1
-
5
-
-
84876534007
-
Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology
-
Prabhakar U, Maeda H, Jain RK, Sevick-Muraca EM, Zamboni W, Farokhzad OC, et al. Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology. Cancer Res 2013;73:2412-7.
-
(2013)
Cancer Res
, vol.73
, pp. 2412-2417
-
-
Prabhakar, U.1
Maeda, H.2
Jain, R.K.3
Sevick-Muraca, E.M.4
Zamboni, W.5
Farokhzad, O.C.6
-
6
-
-
34547690726
-
Immunological properties of engineered nanomaterials
-
Dobrovolskaia MA, McNeil SE. Immunological properties of engineered nanomaterials. Nat Nanotechnol 2007;2:469-78.
-
(2007)
Nat Nanotechnol
, vol.2
, pp. 469-478
-
-
Dobrovolskaia, M.A.1
McNeil, S.E.2
-
8
-
-
51049104302
-
Pharmacokinetics and biodistribution of nanoparticles
-
Li S, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm 2008;5:496-504.
-
(2008)
Mol Pharm
, vol.5
, pp. 496-504
-
-
Li, S.1
Huang, L.2
-
9
-
-
84856759606
-
Factors affecting the pharmacokinetics of pegylated liposomal doxorubicin in patients
-
La-Beck NM, Zamboni BA, Gabizon A, Schmeeda H, Amantea M, Gehrig PA, et al. Factors affecting the pharmacokinetics of pegylated liposomal doxorubicin in patients. Cancer Chemother Pharmacol 2012;69:43-50.
-
(2012)
Cancer Chemother Pharmacol
, vol.69
, pp. 43-50
-
-
La-Beck, N.M.1
Zamboni, B.A.2
Gabizon, A.3
Schmeeda, H.4
Amantea, M.5
Gehrig, P.A.6
-
10
-
-
84865232192
-
Factors affecting the pharmacokinetics and pharmacodynamics of liposomal drugs
-
Song G, Wu H, Yoshino K, Zamboni WC. Factors affecting the pharmacokinetics and pharmacodynamics of liposomal drugs. J Liposome Res 2012;22:177-92.
-
(2012)
J Liposome Res
, vol.22
, pp. 177-192
-
-
Song, G.1
Wu, H.2
Yoshino, K.3
Zamboni, W.C.4
-
11
-
-
84859937689
-
Interpatient pharmacokinetic and pharmacodynamic variability of carrier-mediated anticancer agents
-
Caron W, Song G, Kumar P, Rawal S, Zamboni W. Interpatient pharmacokinetic and pharmacodynamic variability of carrier-mediated anticancer agents. Clin Pharmacol Ther 2012;91:802-12.
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 802-812
-
-
Caron, W.1
Song, G.2
Kumar, P.3
Rawal, S.4
Zamboni, W.5
-
12
-
-
79956133712
-
Bidirectional pharmacodynamic interaction between pegylated liposomal CKD-602 (S-CKD602) and monocytes in patients with refractory solid tumors
-
Zamboni WC, Maruca LJ, Strychor S, Zamboni BA, Ramalingam S, Edwards RP, et al. Bidirectional pharmacodynamic interaction between pegylated liposomal CKD-602 (S-CKD602) and monocytes in patients with refractory solid tumors. J Liposome Res 2011; 21:158-65.
-
(2011)
J Liposome Res
, vol.21
, pp. 158-165
-
-
Zamboni, W.C.1
Maruca, L.J.2
Strychor, S.3
Zamboni, B.A.4
Ramalingam, S.5
Edwards, R.P.6
-
13
-
-
20444412646
-
Therapeutic targeting of the tumor microenvironment
-
Joyce JA. Therapeutic targeting of the tumor microenvironment. Cancer Cell 2005;7:513.
-
(2005)
Cancer Cell
, vol.7
, pp. 513
-
-
Joyce, J.A.1
-
14
-
-
0038066574
-
Host microenvironment in breast cancer development: Inflammatory cells, cytokines and chemokines in breast cancer progression-reciprocal tumor-microenvironment interactions
-
Ben-Baruch A. Host microenvironment in breast cancer development: inflammatory cells, cytokines and chemokines in breast cancer progression-reciprocal tumor-microenvironment interactions. Breast Cancer Res 2002;5:31.
-
(2002)
Breast Cancer Res
, vol.5
, pp. 31
-
-
Ben-Baruch, A.1
-
15
-
-
0018141482
-
Tumor heterogeneity and the biology of cancer invasion and metastasis
-
Fidler IJ. Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res 1978;38:2651-60.
-
(1978)
Cancer Res
, vol.38
, pp. 2651-2660
-
-
Fidler, I.J.1
-
16
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, et al. Molecular portraits of human breast tumours. Nature 2000; 406:747-52.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sørlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
-
18
-
-
37249076385
-
Plasma, tumor, and tissue disposition of STEALTH liposomal CKD-602 (S-CKD602) and nonliposomal CKD-602 in mice bearing A375 human melanoma xenografts
-
Zamboni WC, Strychor S, Joseph E, Walsh DR, Zamboni BA, Parise RA, et al. Plasma, tumor, and tissue disposition of STEALTH liposomal CKD-602 (S-CKD602) and nonliposomal CKD-602 in mice bearing A375 human melanoma xenografts. Clin Cancer Res 2007;13:7217-23.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7217-7223
-
-
Zamboni, W.C.1
Strychor, S.2
Joseph, E.3
Walsh, D.R.4
Zamboni, B.A.5
Parise, R.A.6
-
19
-
-
34548863946
-
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007;8:R76.
-
(2007)
Genome Biol
, vol.8
, pp. R76
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
Mikaelian, I.4
Usary, J.5
Hu, Z.6
-
20
-
-
84883474409
-
Predicting drug responsiveness in human cancers using genetically engineered mice
-
Usary JE, Zhao W, Darr D, Roberts PJ, Liu M, Balletta L, et al. Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res 2013;19:4889-99.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4889-4899
-
-
Usary, J.E.1
Zhao, W.2
Darr, D.3
Roberts, P.J.4
Liu, M.5
Balletta, L.6
-
21
-
-
0028116952
-
Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3 (1) simian virus 40 large tumor antigen fusion gene
-
Maroulakou IG, Anver M, Garrett L, Green JE. Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3 (1) simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci 1994;91:11236-40.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 11236-11240
-
-
Maroulakou, I.G.1
Anver, M.2
Garrett, L.3
Green, J.E.4
-
22
-
-
84863116087
-
Comparative oncogenomics identifi es breast tumors enriched in functional tumor-initiating cells
-
Herschkowitz JI, Zhao W, Zhang M, Usary J, Murrow G, Edwards D, et al. Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci 2012;109: 2778-83.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 2778-2783
-
-
Herschkowitz, J.I.1
Zhao, W.2
Zhang, M.3
Usary, J.4
Murrow, G.5
Edwards, D.6
-
23
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat A, Parker JS, Karginova O, Fan C, Livasy C, Herschkowitz JI, et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 2010;12:R68.
-
(2010)
Breast Cancer Res
, vol.12
, pp. R68
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
Fan, C.4
Livasy, C.5
Herschkowitz, J.I.6
-
24
-
-
84894921345
-
Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis
-
Harrell JC, Pfefferle AD, Zalles N, Prat A, Fan C, Khramtsov A, et al. Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis. Clin Exp Metastasis 2014;31:33-45.
-
(2014)
Clin Exp Metastasis
, vol.31
, pp. 33-45
-
-
Harrell, J.C.1
Pfefferle, A.D.2
Zalles, N.3
Prat, A.4
Fan, C.5
Khramtsov, A.6
-
26
-
-
84911373932
-
The development of liposomal and nanoparticle anticancer agents: Methods to evaluate the encapsulated and released drug in plasma and tumor and phenotypic probes for pharmacokinetic (PK) and pharmacodynamic (PD) disposition
-
Florida: CRC Press
-
Zamboni W, Edwards R, Mountz J, Eiseman J, Basse P, Zamboni B, et al. The development of liposomal and nanoparticle anticancer agents: methods to evaluate the encapsulated and released drug in plasma and tumor and phenotypic probes for pharmacokinetic (PK) and pharmacodynamic (PD) disposition. Proceedings of the 2007NSTI nanotechnology conference; Florida: CRC Press; 2007.
-
(2007)
Proceedings of the 2007 NSTI Nanotechnology Conference
-
-
Zamboni, W.1
Edwards, R.2
Mountz, J.3
Eiseman, J.4
Basse, P.5
Zamboni, B.6
-
27
-
-
84863393851
-
Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis
-
Takahashi O, Komaki R, Smith PD, Jürgensmeier JM, Ryan A, Bekele BN, et al. Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis. Clin Cancer Res 2012;18:1641-54.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1641-1654
-
-
Takahashi, O.1
Komaki, R.2
Smith, P.D.3
Jürgensmeier, J.M.4
Ryan, A.5
Bekele, B.N.6
-
28
-
-
6344250782
-
Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer
-
Ohno S, Ohno Y, Suzuki N, Kamei T, Koike K, Inagawa H, et al. Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer. Anticancer Res 2004;24:3335-42.
-
(2004)
Anticancer Res
, vol.24
, pp. 3335-3342
-
-
Ohno, S.1
Ohno, Y.2
Suzuki, N.3
Kamei, T.4
Koike, K.5
Inagawa, H.6
-
29
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006;66:605-12.
-
(2006)
Cancer Res
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
30
-
-
12344293902
-
Angiogenic and lymphangiogenic microvessel density in breast carcinoma: Correlation with clinicopathologic parameters and VEGF-family gene expression
-
Choi WW, Lewis MM, Lawson D, Yin-Goen Q, Birdsong GG, Cotsonis GA, et al. Angiogenic and lymphangiogenic microvessel density in breast carcinoma: Correlation with clinicopathologic parameters and VEGF-family gene expression. Mod Pathol 2004;18:143-52.
-
(2004)
Mod Pathol
, vol.18
, pp. 143-152
-
-
Choi, W.W.1
Lewis, M.M.2
Lawson, D.3
Yin-Goen, Q.4
Birdsong, G.G.5
Cotsonis, G.A.6
-
31
-
-
0032695910
-
Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: Dynamics of receptor inhibition in situ and antitumor effects in athymic mice
-
Pollack VA, Savage DM, Baker DA, Tsaparikos KE, Sloan DE, Moyer JD, et al. Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice. J Pharmacol Exp Ther 1999;291:739-48.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 739-748
-
-
Pollack, V.A.1
Savage, D.M.2
Baker, D.A.3
Tsaparikos, K.E.4
Sloan, D.E.5
Moyer, J.D.6
-
32
-
-
0028859126
-
Applying bailer's method for AUC confidence intervals to sparse sampling
-
Nedelman JR, Gibiansky E, Lau DT. Applying bailer's method for AUC confidence intervals to sparse sampling. Pharm Res 1995;12:124-8.
-
(1995)
Pharm Res
, vol.12
, pp. 124-128
-
-
Nedelman, J.R.1
Gibiansky, E.2
Lau, D.T.3
-
33
-
-
3142543163
-
The use of percentage change from baseline as an outcome in a controlled trial is statistically inef ficient: A simulation study
-
Vickers AJ. The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study. BMC Med Res Methodol 2001;1:6.
-
(2001)
BMC Med Res Methodol
, vol.1
, pp. 6
-
-
Vickers, A.J.1
-
34
-
-
47749097074
-
The inflammatory chemokines CCL2 and CCL5 in breast cancer
-
Soria G, Ben-Baruch A. The inflammatory chemokines CCL2 and CCL5 in breast cancer. Cancer Lett 2008;267:271-85.
-
(2008)
Cancer Lett
, vol.267
, pp. 271-285
-
-
Soria, G.1
Ben-Baruch, A.2
-
35
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett CG, Boucher Y, di Tomaso E, Duda DG, Munn LL, Tong RT, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004; 10:145-7.
-
(2004)
Nat Med
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
Di Tomaso, E.3
Duda, D.G.4
Munn, L.L.5
Tong, R.T.6
-
36
-
-
77952812169
-
Guidelines for the welfare and use of animals in cancer research
-
Workman P, Aboagye E, Balkwill F, Balmain A, Bruder G, Chaplin D, et al. Guidelines for the welfare and use of animals in cancer research. Br J Cancer 2010;102:1555-77.
-
(2010)
Br J Cancer
, vol.102
, pp. 1555-1577
-
-
Workman, P.1
Aboagye, E.2
Balkwill, F.3
Balmain, A.4
Bruder, G.5
Chaplin, D.6
-
37
-
-
38049131877
-
A cellular trojan horse for delivery of therapeutic nanoparticles into tumors
-
Choi M, Stanton-Maxey KJ, Stanley JK, Levin CS, Bardhan R, Akin D, et al. A cellular trojan horse for delivery of therapeutic nanoparticles into tumors. Nano Lett 2007;7:3759-65.
-
(2007)
Nano Lett
, vol.7
, pp. 3759-3765
-
-
Choi, M.1
Stanton-Maxey, K.J.2
Stanley, J.K.3
Levin, C.S.4
Bardhan, R.5
Akin, D.6
-
38
-
-
46749088943
-
Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil
-
Banciu M, Schiffelers RM, Storm G. Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil. Pharm Res 2008;25:1948-55.
-
(2008)
Pharm Res
, vol.25
, pp. 1948-1955
-
-
Banciu, M.1
Schiffelers, R.M.2
Storm, G.3
-
39
-
-
84872300769
-
Molecular targeting of liposomal nanoparticles to tumor microenvironment
-
Zhao G, Rodriguez BL. Molecular targeting of liposomal nanoparticles to tumor microenvironment. Int J Nanomedicine 2013;8:61.
-
(2013)
Int J Nanomedicine
, vol.8
, pp. 61
-
-
Zhao, G.1
Rodriguez, B.L.2
-
40
-
-
0023933718
-
Release of doxorubicin from peritoneal macrophages exposed in vivo to doxorubicin-containing liposomes
-
Storm G, Steerenberg P, Emmen F, van Borssum Waalkes M, Crommelin D. Release of doxorubicin from peritoneal macrophages exposed in vivo to doxorubicin-containing liposomes. Biochim Biophys Acta 1988;965:136-45.
-
(1988)
Biochim Biophys Acta
, vol.965
, pp. 136-145
-
-
Storm, G.1
Steerenberg, P.2
Emmen, F.3
Van Borssum Waalkes, M.4
Crommelin, D.5
-
41
-
-
0035447414
-
Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma
-
Saji H, Koike M, Yamori T, Saji S, Seiki M, Matsushima K, et al. Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer 2001;92:1085-91.
-
(2001)
Cancer
, vol.92
, pp. 1085-1091
-
-
Saji, H.1
Koike, M.2
Yamori, T.3
Saji, S.4
Seiki, M.5
Matsushima, K.6
-
42
-
-
84867771909
-
CCL2/ CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein-and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms
-
Fang WB, Jokar I, Zou A, Lambert D, Dendukuri P, Cheng N. CCL2/ CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein-and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms. J Biol Chem 2012; 287:36593-608.
-
(2012)
J Biol Chem
, vol.287
, pp. 36593-36608
-
-
Fang, W.B.1
Jokar, I.2
Zou, A.3
Lambert, D.4
Dendukuri, P.5
Cheng, N.6
-
43
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
-
Qian B, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 2011;475:222-5.
-
(2011)
Nature
, vol.475
, pp. 222-225
-
-
Qian, B.1
Li, J.2
Zhang, H.3
Kitamura, T.4
Zhang, J.5
Campion, L.R.6
-
44
-
-
84892942936
-
CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy
-
Ma Y, Mattarollo SR, Adjemian S, Yang H, Aymeric L, Hannani D, et al. CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res 2014;74:436-45.
-
(2014)
Cancer Res
, vol.74
, pp. 436-445
-
-
Ma, Y.1
Mattarollo, S.R.2
Adjemian, S.3
Yang, H.4
Aymeric, L.5
Hannani, D.6
-
45
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 2008;8:592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
46
-
-
77951498489
-
Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis
-
Ferrara N. Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis. Curr Opin Hematol 2010;17:219-24.
-
(2010)
Curr Opin Hematol
, vol.17
, pp. 219-224
-
-
Ferrara, N.1
-
48
-
-
20444441548
-
Cancer: Inflammation by remote control
-
Mantovani A. Cancer: inflammation by remote control. Nature 2005;435:752-3.
-
(2005)
Nature
, vol.435
, pp. 752-753
-
-
Mantovani, A.1
-
49
-
-
4944266313
-
High interstitial fluid pressure - An obstacle in cancer therapy
-
Heldin C, Rubin K, Pietras K, Östman A. High interstitial fluid pressure - an obstacle in cancer therapy. Nat Rev Cancer 2004;4:806-13.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 806-813
-
-
Heldin, C.1
Rubin, K.2
Pietras, K.3
Östman, A.4
-
50
-
-
84863655863
-
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
-
Chauhan VP, Stylianopoulos T, Martin JD, Popović Z, Chen O, Kamoun WS, et al. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nat Nanotechnol 2012;7:383-8.
-
(2012)
Nat Nanotechnol
, vol.7
, pp. 383-388
-
-
Chauhan, V.P.1
Stylianopoulos, T.2
Martin, J.D.3
Popović, Z.4
Chen, O.5
Kamoun, W.S.6
|