Recent advances in the diagnosis and management of tuberculous meningitis

Current Opinion in Infectious Diseases

Volumn 30, Issue 1, 2017, Pages 123-128

  Mai, Nguyen T H ^a   Thwaites, Guy E ^b,c  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^b OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Critical care; Diagnosis; Management; Tuberculous meningitis

Indexed keywords

TUBERCULOSTATIC AGENT;

BACTERIUM CULTURE; BRAIN INFARCTION; CEREBROSPINAL FLUID ANALYSIS; CLINICAL DECISION MAKING; DIAGNOSTIC TEST; HUMAN; HYDROCEPHALUS; HYPONATREMIA; INFARCTION; INTRACRANIAL PRESSURE; LOOP MEDIATED ISOTHERMAL AMPLIFICATION; MOLECULAR DIAGNOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEIC ACID AMPLIFICATION; OUTCOME ASSESSMENT; REVIEW; TUBERCULOUS MENINGITIS; COMPLICATION; SENSITIVITY AND SPECIFICITY; STANDARDS;

ANTITUBERCULAR AGENTS; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; SENSITIVITY AND SPECIFICITY; TUBERCULOSIS, MENINGEAL;

EID: 84992735652     PISSN: 09517375     EISSN: 14736527     Source Type: Journal    
DOI: 10.1097/QCO.0000000000000331     Document Type: Review

References (36)

1. Thwaites GE, van Toorn R, Schoeman J. Tuberculous meningitis: more questions, still too few answers. Lancet Neurol 2013; 12:999-1010.
2. Thwaites GE, Chau TT, Farrar JJ. Improving the bacteriological diagnosis of tuberculous meningitis. J Clin Microbiol 2004; 42:378-379.
3. Patel VB, Theron G, Lenders L, et al. Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study. PLoS Med 2013; 10:e1001536.
4. Nhu NT, Heemskerk D, Thu do DA, et al. Evaluation ofGeneXpert MTB/RIF for diagnosis of tuberculous meningitis. J Clin Microbiol 2014; 52:226-233.
5. Bahr NC, Tugume L, Rajasingham R, et al. Improved diagnostic sensitivity for tuberculous meningitis with Xpert((R)) MTB/RIF of centrifuged CSF. Int J Tuberc Lung Dis 2015; 19:1209-1215.
6. Boyles TH, Thwaites GE. Appropriate use of the Xpert(R) MTB/RIF assay in suspected tuberculous meningitis. Int J Tuberc Lung Dis 2015; 19: 276-277.
7. Bahr NC, Marais S, Caws M, et al. Tuberculous Meningitis International Research C: GeneXpert MTB/Rif to diagnose tuberculous meningitis: perhaps the first test but not the last. Clin Infect Dis 2016; 62:1133-1135.
8. Modi M, Sharma K, Sharma M, et al. Multitargeted loop-mediated isothermal amplification for rapid diagnosis of tuberculous meningitis. Int J Tuberc Lung Dis 2016; 20:625-630.
9. Cox JA, Lukande RL, Kalungi S, et al. Accuracy of lipoarabinomannan and Xpert MTB/RIF testing in cerebrospinal fluid to diagnose tuberculous meningitis in an autopsy cohort of HIV-infected adults. J Clin Microbiol 2015; 53:2667-2673.
10. Bahr NC, Tugume L, Boulware DR. A word of caution in considering the use of the lipoarabinomannan lateral flow assay on cerebrospinal fluid for detection of tuberculous meningitis. J Clin Microbiol 2016; 54:241-242.
11. Patel VB, Bhigjee AI, Paruk HF, et al. Utility of a novel lipoarabinomannan assay for the diagnosis of tuberculous meningitis in a resource-poor high-HIV prevalence setting. Cerebrospinal Fluid Res 2009; 6:13.
12. Yu J, Wang ZJ, Chen LH, Li HH. Diagnostic accuracy of interferon-gamma release assays for tuberculous meningitis: a meta-analysis. Int J Tuberc Lung Dis 2016; 20:494-499.
13. Nguyen TH, Thwaites GE. The current pharmacological landscape of tuberculous meningitis: where to next? Expert Rev Clin Pharmacol 2016; 9:625-627.
14. Ruslami R, Ganiem AR, Dian S, et al. Intensified regimen containing rifampicin and moxifloxacin for tuberculous meningitis: an open-label, randomised controlled phase 2 trial. Lancet Infect Dis 2013; 13:27-35.
15. Te Brake L, Dian S, Ganiem AR, et al. Pharmacokinetic/pharmacodynamic analysis of an intensified regimen containing rifampicin and moxifloxacin for tuberculous meningitis. Int J Antimicrob Agents 2015; 45:496-503.
16. Yunivita V, Dian S, Ganiem AR, et al. Pharmacokinetics and safety/tolerability of higher oral and intravenous doses of rifampicin in adult tuberculous meningitis patients. Int J Antimicrob Agents 2016; 48:415-421.
17. Heemskerk AD, Bang ND, Mai NT, et al. Intensified antituberculosis therapy in adults with tuberculous meningitis. N Engl J Med 2016; 374:124-134.
18. van Crevel R, Ruslami R, Aarnoutse R. Therapy for tuberculous meningitis. N Engl J Med 2016; 374:2187.
19. Boeree MJ, Gillespie SH, Hoelscher M; Pan Act. Therapy for tuberculous meningitis. N Engl J Med 2016; 374:2187-2188.
20. Heemskerk AD, Bang ND, Thwaites GE. Therapy for tuberculous meningitis. N Engl J Med 2016; 374:2188-2189.
21. World Health Organization. Guidance for national tuberculosis programmes on the management of tuberculosis in children. 2nd ed. Geneva: WHO; 2014.
22. van Toorn R, Schaaf HS, Laubscher JA, et al. Short intensified treatment in children with drug-susceptible tuberculous meningitis. Pediatr Infect Dis J 2014; 33:248-252.
23. Savic RM, Ruslami R, Hibma JE, et al. Pediatric tuberculous meningitis: model-based approach to determining optimal doses of the antituberculosis drugs rifampicin and levofloxacin for children. Clin Pharmacol Ther 2015; 98:622-629.
24. Li H, Lu J, Liu J, et al. Linezolid is associated with improved early outcomes of childhood tuberculous meningitis. Pediatr Infect Dis J 2016; 35:607-610.
25. Akkerman OW,Odish OF, Bolhuis MS, et al. Pharmacokinetics of bedaquiline in cerebrospinal fluid and serum in multidrug-resistant tuberculous meningitis. Clin Infect Dis 2016; 62:523-524.
26. Prasad K, Singh MB, Ryan H. Corticosteroids for managing tuberculous meningitis. Cochrane Database Syst Rev 2016; 4:CD002244.
27. Lu TT, Lin XQ, Zhang L, et al. Magnetic resonance angiography manifestations and prognostic significance in HIV-negative tuberculosis meningitis. Int J Tuberc Lung Dis 2015; 19:1448-1454.
28. Chatterjee D, Radotra BD, Vasishta RK, Sharma K. Vascular complications of tuberculous meningitis: an autopsy study. Neurol India 2015; 63:926-932.
29. Singh AK, Malhotra HS, Garg RK, et al. Paradoxical reaction in tuberculous meningitis: presentation, predictors and impact on prognosis. BMC Infect Dis 2016; 16:306.
30. Marais S, Wilkinson KA, Lesosky M, et al. Neutrophil-associated central nervous system inflammation in tuberculous meningitis immune reconstitution inflammatory syndrome. Clin Infect Dis 2014; 59:1638-1647.
31. Misra UK, Kalita J, Bhoi SK, Singh RK. A study of hyponatremia in tuberculous meningitis. J Neurol Sci 2016; 367:152-157.
32. Figaji AA, Fieggen AG. The neurosurgical and acute care management of tuberculous meningitis: evidence and current practice. Tuberculosis (Edinb) 2010; 90:393-400.
33. Whitson MR, Mayo PH. Ultrasonography in the emergency department. Crit Care 2016; 20:227.
34. Kelly N, Esteve R, Papadimos TJ, et al. Clinician-performed ultrasound in hemodynamic and cardiac assessment: a synopsis of current indications and limitations. Eur J Trauma Emerg Surg 2015; 41:469-480.
35. Ohle R, McIsaac SM, Woo MY, Perry JJ. Sonography of the optic nerve sheath diameter for detection of raised intracranial pressure compared to computed tomography: a systematic review and meta-analysis. J Ultrasound Med 2015; 34:1285-1294.
36. Sangani SV, Parikh S. Can sonographic measurement of optic nerve sheath diameter be used to detect raised intracranial pressure in patients with tuberculous meningitis? A prospective observational study. Indian J Radiol Imaging 2015; 25:173-176.