Linezolid is associated with improved early outcomes of childhood tuberculous meningitis

Pediatric Infectious Disease Journal

Volumn 35, Issue 6, 2016, Pages 607-610

  Li, Huimin ^a   Lu, Jie ^a,b   Liu, Jinrong ^a   Zhao, Yuhong ^a   Ni, Xin ^a,b   Zhao, Shunying ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Pediatric Institute   (China)

Author keywords

Children; Linezolid; Treatment; Tuberculosis meningitis

Indexed keywords

ETHAMBUTOL; ISONIAZID; LINEZOLID; PYRAZINAMIDE; RIFAMPICIN; ANTIINFECTIVE AGENT;

ARTICLE; CHILD; DRUG EFFICACY; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; HUMAN; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; THROMBOCYTOPENIA; TREATMENT OUTCOME; TUBERCULOUS MENINGITIS; ADOLESCENT; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; INFANT; NEWBORN; PRESCHOOL CHILD; TUBERCULOSIS, MENINGEAL;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; LINEZOLID; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; TUBERCULOSIS, MENINGEAL;

EID: 84959172818     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0000000000001114     Document Type: Article

References (29)

1. Hosoglu S, Geyik MF, Balik I, et al. Predictors of outcome in patients with tuberculous meningitis. Int J Tuberc Lung Dis. 2002;6:64-70.
2. Thwaites GE, Nguyen DB, Nguyen HD, et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med. 2004;351:1741-1751.
3. Ho J, Marais BJ, Gilbert GL, et al. Diagnosing tuberculous meningitis-have we made any progress? Trop Med Int Health. 2013;18:783-793.
4. Thwaites GE. Advances in the diagnosis and treatment of tuberculous meningitis. Curr Opin Neurol. 2013;26:295-300.
5. Thwaites GE, van Toorn R, Schoeman J. Tuberculous meningitis: more questions, still too few answers. Lancet Neurol. 2013;12:999-1010.
6. Principi N, Esposito S. Diagnosis and therapy of tuberculous meningitis in children. Tuberculosis (Edinb). 2012;92:377-383.
7. Joint Tuberculosis Committee of the British Thoracic Society. Chemotherapy and management of tuberculosis in the United Kingdom: recommendations 1998. Thorax. 1998;53:536-548.
8. WHO Guidelines Approved by the Guidelines Review Committee. Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children. 2nd ed. Geneva: World Health Organization; 2014.
9. Zhang Z, Pang Y, Wang Y, et al. Beijing genotype of Mycobacterium tuberculosis is significantly associated with linezolid resistance in multidrug-resistant and extensively drug-resistant tuberculosis in China. Int J Antimicrob Agents. 2014;43:231-235.
10. Alcalá L, Ruiz-Serrano MJ, Pérez-Fernández Turégano C, et al. In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs. Antimicrob Agents Chemother. 2003;47:416-417.
11. Dietze R, Hadad DJ, McGee B, et al. Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis. Am J Respir Crit Care Med. 2008;178:1180-1185.
12. Cynamon MH, Klemens SP, Sharpe CA, et al. Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model. Antimicrob Agents Chemother. 1999;43:1189-1191.
13. World Health Organization. Policy Guidance on Drug-susceptibility Testing (DST) of Second-line Antituberculosis Drugs. Geneva: World Health Organization; 2006.
14. Fortún J, Martín-Dávila P, Navas E, et al. Linezolid for the treatment of multidrug-resistant tuberculosis. J Antimicrob Chemother. 2005;56:180-185.
15. Schecter GF, Scott C, True L, et al. Linezolid in the treatment of multidrugresistant tuberculosis. Clin Infect Dis. 2010;50:49-55.
16. Anger HA, Dworkin F, Sharma S, et al. Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000-06. J Antimicrob Chemother. 2010;65:775-783.
17. Sun F, Ruan Q, Wang J, et al. Linezolid manifests a rapid and dramatic therapeutic effect for patients with life-threatening tuberculous meningitis. Antimicrob Agents Chemother. 2014;58:6297-6301.
18. van Well GT, Paes BF, Terwee CB, et al. Twenty years of pediatric tuberculous meningitis: A retrospective cohort study in the western cape of South Africa. Pediatrics. 2009;123:e1-e8.
19. Thwaites GE, Nguyen DB, Nguyen HD, et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med. 2004;351:1741-1751.
20. Schaaf HS, Marais BJ. Management of multidrug-resistant tuberculosis in children: A survival guide for paediatricians. Paediatr Respir Rev. 2011;12:31-38.
21. Le J, Lieberman JM. Management of community-associated methicillinresistant Staphylococcus aureus infections in children. Pharmacotherapy. 2006;26:1758-1770.
22. Xia H, Song YY, Zhao B, et al. Multicentre evaluation of Ziehl-Neelsen and light-emitting diode fluorescence microscopy in China. Int J Tuberc Lung Dis. 2013;17:107-112.
23. Thwaites GE, Chau TT, Stepniewska K, et al. Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features. Lancet. 2002;360:1287-1292.
24. Garcia-Prats AJ, Rose PC, Hesseling AC, et al. Linezolid for the treatment of drug-resistant tuberculosis in children: A review and recommendations. Tuberculosis (Edinb). 2014;94:93-104.
25. Zhao Y, Xu S, Wang L, et al. National survey of drug-resistant tuberculosis in China. N Engl J Med. 2012;366:2161-2170.
26. Jungbluth GL, Welshman IR, Hopkins NK. Linezolid pharmacokinetics in pediatric patients: an overview. Pediatr Infect Dis J. 2003;22(9 Suppl):S153-S157.
27. Marshall GS. Prolonged and recurrent fevers in children. J Infect. 2014;68 (Suppl 1):S83-S93.
28. Vinh DC, Rubinstein E. Linezolid: A review of safety and tolerability. J Infect. 2009;59 (Suppl 1):S59-S74.
29. Lee M, Lee J, Carroll MW, et al. Linezolid for treatment of chronic extensively drug-resistant tuberculosis. N Engl J Med. 2012;367:1508-1518.