Human Serum Metabolites Associate With Severity and Patient Outcomes in Traumatic Brain Injury

EBioMedicine

Volumn 12, Issue , 2016, Pages 118-126

  Orešič, Matej ^a,b,c   Posti, Jussi P ^a,d   Kamstrup Nielsen, Maja H ^b   Takala, Riikka S K ^d   Lingsma, Hester F ^e   Mattila, Ismo ^b,c   Jäntti, Sirkku ^c   Katila, Ari J ^d   Carpenter, Keri L H ^f   Ala Seppälä, Henna ^a,d   Kyllönen, Anna ^a,d   Maanpää, Henna Riikka ^a,d   Tallus, Jussi ^a,d   Coles, Jonathan P ^f   Heino, Iiro ^a,d   Frantzén, Janek ^a,d   Hutchinson, Peter J ^f   Menon, David K ^f   Tenovuo, Olli ^a,d   Hyötyläinen, Tuulia ^a,b,c,g,h  

^a UNIVERSITY OF TURKU   (Finland)

^b STENO DIABETES CENTER   (Denmark)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^d TURKU UNIVERSITY HOSPITAL   (Finland)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^h ÖREBRO UNIVERSITY   (Sweden)

Author keywords

Biomarkers; Mass spectrometry; Metabolomics; Traumatic brain injury

Indexed keywords

2,3 DIPHOSPHOGLYCERIC ACID; 3 HYDROXYBUTYRIC ACID; CARBOHYDRATE DERIVATIVE; DECANOIC ACID; MEDIUM CHAIN FATTY ACID; OCTANOIC ACID; PROPOFOL; BIOLOGICAL MARKER;

ACCELERATION; ADULT; AREA UNDER THE CURVE; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DECELERATION; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; DOWN REGULATION; FALLING; FALSE POSITIVE RESULT; FEMALE; GLASGOW COMA SCALE; HEAD INJURY; HUMAN; MAJOR CLINICAL STUDY; MALE; MASS FRAGMENTOGRAPHY; METABOLOMICS; MICRODIALYSIS; MULTICENTER STUDY; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; TRAUMATIC BRAIN INJURY; UPREGULATION; VIOLENCE; ADOLESCENT; AGED; BLOOD; BRAIN INJURIES, TRAUMATIC; CLINICAL TRIAL; METABOLOME; MIDDLE AGED; MORTALITY; PROCEDURES; PROGNOSIS; REPRODUCIBILITY; SEVERITY OF ILLNESS INDEX; VERY ELDERLY; WORKFLOW; X-RAY COMPUTED TOMOGRAPHY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS; BRAIN INJURIES, TRAUMATIC; FEMALE; GLASGOW COMA SCALE; HUMANS; MALE; METABOLOME; METABOLOMICS; MIDDLE AGED; PATIENT OUTCOME ASSESSMENT; PROGNOSIS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; ROC CURVE; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, X-RAY COMPUTED; WORKFLOW; YOUNG ADULT;

EID: 84992650319     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2016.07.015     Document Type: Article

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